Lemur catta (Ring-tailed lemur): 123628224
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Entry
123628224 CDS
T08326
Symbol
TOP2B
Name
(RefSeq) DNA topoisomerase 2-beta isoform X1
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
lcat
Lemur catta (Ring-tailed lemur)
Pathway
lcat01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
lcat00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
123628224 (TOP2B)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
lcat03032
]
123628224 (TOP2B)
03036 Chromosome and associated proteins [BR:
lcat03036
]
123628224 (TOP2B)
Enzymes [BR:
lcat01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
123628224 (TOP2B)
DNA replication proteins [BR:
lcat03032
]
Eukaryotic type
DNA Topoisomerases
123628224 (TOP2B)
Chromosome and associated proteins [BR:
lcat03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
123628224 (TOP2B)
Centrosome formation proteins
Centriole proteins
123628224 (TOP2B)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
Toprim
HATPase_c
DUF7180
Motif
Other DBs
NCBI-GeneID:
123628224
NCBI-ProteinID:
XP_045393813
LinkDB
All DBs
Position
1:155063136..155126871
Genome browser
AA seq
1623 aa
AA seq
DB search
MAKSGGGGVGASAGGNGALTWVTLFDQNNAAKNEESETANKNDSSKKLSVERVYQKKTQL
EHILLRPDTYIGSVEPLTQVMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDK
NMTCIKVSIDPESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTG
GRNGYGAKLCNIFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQ
PDLPKFKMEKLDKDIVALMTKRAYDLAGSCKGVKVMFNGKKLPVNGFRSYVDLYVKDKLD
ETGVALKVIHELANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEV
VKKKNKAGVSVKPFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFK
AASNCGIVESILNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILT
EGDSAKSLAVSGLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKK
SYDDAESLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKA
SKNKQELSFYSIPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRY
AGPEDDAAITLAFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFIN
KELILFSNSDNERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHG
EQALMMTIVNLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSSLARLLFPA
VDDNLLKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRML
DGLDPHPMLPNYKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVL
EPMLNGTDKTPALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSM
VLFDHMGCLKKYETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQ
GKITIENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEEETQNQHDDSSSDSGTPSGP
DFNYILNMSLWSLTKEKVEELIKQRDSKGREVNDLKRKSPSDLWKEDLAAFVEELDKVEA
QEREDVLAGMSGKAIKGKVGKPKVKKLQLEETMPSPYGRRIIPEITAMKADASKKLLKRK
KGDLDTTVVKVEFDEEFGGTPVGGAGEEALTPSVPLNRGPKPKRERKEPGTRVRKTPTSS
GKPSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDD
ADDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSSHDKKSQ
DFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKLPSKTVAAKKGKPSSD
TASKPKRAPKQKKIVETVNSDSDSEFGIPKKTAAPKGKGRGAKKRKASGSENEADYNPAR
KIPKTTSKKPKKTSFDQDSDVDIFPSDFTSEPPSLPRTGRARKEVKYFTESDEEEDVDFA
MFN
NT seq
4872 nt
NT seq
+upstream
nt +downstream
nt
atggccaagtcgggtggcggcggcgtgggagccagcgcgggcggcaacggggcgctgacc
tgggtgactctttttgatcagaacaatgctgcaaaaaatgaagagtcggagaccgcaaac
aaaaatgattcttcaaagaagttgtctgttgagagagtgtatcagaagaagacacaactt
gaacacattcttcttcgtcccgatacatacattgggtcagtggagccattgacccaggta
atgtgggtgtatgatgaagatgtagggatgaattgcagagaggttacctttgtgccaggt
ttatacaagatctttgatgaaattttggttaatgctgcagacaataaacagagggataag
aacatgacctgtattaaagtttctattgatcctgaatctaacattataagcatttggaat
aatgggaaaggcattccagtagtagaacacaaagtagagaaagtttatgttcctgcttta
atttttggacagcttttaacatctagtaactatgatgatgatgagaaaaaagttacaggt
ggtcgcaatggttatggtgcaaaactttgtaatattttcagtacaaagtttacagtagaa
acagcttgcaaagagtacaaacacagttttaagcagacatggatgaataatatgatgaag
acttctgaagccaaaattaaacattttgatggtgaagattacacatgcataacattccaa
ccagatcttcccaaatttaagatggaaaaacttgacaaggacattgtggccctcatgacc
aaaagagcatatgatttggctggttcatgtaaaggggtcaaggtcatgtttaatggaaag
aaattgcctgtaaatggatttcgaagttatgtagatctttatgtgaaagacaaattggat
gaaactggggtggcactgaaagttattcatgaacttgcaaatgaaagatgggatgtttgt
ctcacattgagtgaaaaaggattccagcaaatcagctttgtaaatagtattgcaactaca
aaaggtggacggcatgtggattatgtagtcgatcaggttgtcggtaaattgattgaagta
gttaagaaaaagaacaaagctggtgtatcggtgaaaccatttcaagtaaaaaaccacata
tgggtttttattaattgccttattgaaaatccaacatttgattctcagaccaaggaaaac
atgactctgcagcccaaaagttttgggtccaaatgtcaactgtcagaaaaattttttaaa
gcagcctctaattgtggcattgtagaaagtatcctgaactgggtgaaatttaaggctcag
actcagctgaacaagaagtgttcctcagtaaaatacagtaaaatcaaaggtattcccaaa
ttggatgatgctaatgatgctggtggcaaacattccctggagtgtacactgatattaaca
gagggagactctgccaaatcactggctgtgtctggattaggtgtgattgggcgggacaga
tacggagttttcccactcaggggtaaaattcttaatgtacgggaagcttctcataaacag
atcatggaaaatgcagaaataaacaatattattaaaatagttggtctacaatataagaag
agttatgatgatgcagaatctttgaaaaccttacgttatggaaagattatgattatgact
gatcaggatcaagatggttctcacataaaaggcctgcttattaatttcatccatcacaat
tggccatcgcttttgaagcatggttttcttgaagagttcattactcctattgtaaaggca
agcaaaaataagcaggaactttccttctacagtattcctgaatttgatgagtggaaaaaa
catatagaaaaccagaaagcctggaaaataaaatactacaaaggtttgggtaccagtaca
gctaaagaagcaaaggaatattttgctgatatggaaaggcatcgtatcttgtttagatac
gctggtcctgaagatgatgctgccattaccttggcattcagtaagaagaagattgatgac
agaaaagaatggttaacaaatttcatggaagatcggagacagcgtaggttacatggcttg
ccagagcaatttttatatggtacagcaacaaagcatttgacttacaatgatttcatcaac
aaggaattgattctcttctcaaactcagacaatgaaagatctataccatctcttgttgat
ggctttaaacctgggcaacgaaaagttttatttacctgtttcaagaggaatgataaacgt
gaggtaaaagttgcccagttggctggatctgttgctgaaatgtctgcttatcatcatgga
gaacaagcattgatgatgactattgtcaatttggctcagaactttgtgggaagtaacaac
attaacttgcttcagcctattggtcagtttggaactcggcttcatggtggcaaagatgct
gcaagccctcgttatattttcacaatgttaagctctttagcaagactgctttttcctgct
gtggatgataacttgcttaagttcctttatgatgataatcagcgtgtagagcctgagtgg
tatattcccataattcccatggttttaataaatggtgctgagggcattggtactggatgg
gcttgtaagctacctaactatgatgctagggaaattgtgaacaatgtcagacgaatgcta
gatggcttggatcctcatcccatgcttccaaactacaaaaactttaaaggcacgatccaa
gaacttggtcaaaaccagtatgcagtcagtggtgaaatatttgtagtggatagaaacaca
gtagaaattacagagcttccagttagaacttggacacaggtatacaaagaacaggtttta
gaacctatgctaaatggaacagacaaaacaccagcattaatttctgattataaagaatat
catactgatacaactgtgaagtttgtggtaaaaatgactgaagagaaactagcacaagca
gaagctgctggattgcataaagtttttaaacttcaaactactcttacttgtaattccatg
gtactctttgatcatatgggatgtctgaagaagtatgaaactgtgcaagacattctgaaa
gaattctttgatttacgattaagttattacggtttacgtaaggagtggcttgtaggaatg
ttgggagcagaatctacaaagcttaataatcaagcccgtttcattttagagaagatacaa
gggaaaattactatagagaataggtcaaagaaagatttgattcaaatgttagtccagaga
ggttatgaatctgacccagtgaaagcctggaaagaagcacaagaaaaggcagcagaagag
gaagaaacacaaaaccagcatgatgatagttcctccgattcaggaactccttcaggccct
gattttaattatattttaaatatgtctctgtggtctcttactaaagaaaaagttgaagaa
ctgattaaacaaagagattcaaaagggcgagaggtcaatgatcttaaaagaaaatctcct
tcagatctttggaaagaagatttagcagcatttgttgaagaactggataaagttgaagcg
caagaacgagaagatgttctggctggaatgtcaggaaaagcaataaaaggtaaagttggt
aagcctaaggtgaagaaacttcagttggaagagacaatgccctcaccttatgggagaaga
ataattcctgaaattactgctatgaaagcagatgccagcaaaaagttgctgaagaggaag
aagggtgaccttgataccacagtagtgaaagtggaatttgatgaagaattcggtgggacg
ccggtaggaggcgcaggagaggaggcgttgactccatcagtgcctctaaacagaggtccc
aagcccaaaagggagagaaaggagcctggtaccagggtgagaaaaacacctacatcatct
ggtaaacccagtgcaaagaaagtgaagaaacggaatccttggtcagatgatgaatccaag
tcggaaagtgatttggaagaaacagaacctgtggttattccaagagattctttgcttagg
agagcagctgctgaaagacctaagtacacatttgatttctcagaagaagaggatgatgat
gctgatgatgatgatgacaataatgatttagaggaattgaaagttaaagcatctcccata
acaaatgatggggaagatgaatttgttccttcagatggcttagataaagatgaatataca
ttttcaccaggcaaatcaaaagctactccagaaaaatcttcgcatgacaaaaaaagtcag
gattttggaaatctcttctcatttccttcatattctcagaagtcagaagatgattcagct
aaattcgacagtaatgaagaagattctgcttcggttttttcaccatcatttggtctgaaa
caaacagataaacttccaagtaaaacagtagctgctaaaaagggaaaaccatcttcagat
acagcctctaagcctaagagagcccccaaacagaagaaaatagtagagactgtaaactct
gactcagattcagaatttggcattccaaagaagactgcagcgccaaaaggtaaaggccga
ggggcaaagaaaaggaaagcatctggctctgaaaatgaagctgattataaccctgccagg
aaaatacccaaaacaacaagcaagaaaccgaagaaaacatcatttgatcaggattcggat
gtggacatcttcccctcagacttcacttctgaaccaccttctctgccacggactggtcga
gctaggaaagaagtaaaatattttacagagtctgatgaagaagaagatgttgattttgca
atgtttaattaa
DBGET
integrated database retrieval system
