KEGG   Lemur catta (Ring-tailed lemur): 123631548
Entry
123631548         CDS       T08326                                 
Symbol
RAC1
Name
(RefSeq) ras-related C3 botulinum toxin substrate 1
  KO
K04392  Ras-related C3 botulinum toxin substrate 1
Organism
lcat  Lemur catta (Ring-tailed lemur)
Pathway
lcat04010  MAPK signaling pathway
lcat04014  Ras signaling pathway
lcat04015  Rap1 signaling pathway
lcat04024  cAMP signaling pathway
lcat04062  Chemokine signaling pathway
lcat04071  Sphingolipid signaling pathway
lcat04145  Phagosome
lcat04148  Efferocytosis
lcat04151  PI3K-Akt signaling pathway
lcat04310  Wnt signaling pathway
lcat04360  Axon guidance
lcat04370  VEGF signaling pathway
lcat04380  Osteoclast differentiation
lcat04510  Focal adhesion
lcat04520  Adherens junction
lcat04530  Tight junction
lcat04613  Neutrophil extracellular trap formation
lcat04620  Toll-like receptor signaling pathway
lcat04650  Natural killer cell mediated cytotoxicity
lcat04662  B cell receptor signaling pathway
lcat04664  Fc epsilon RI signaling pathway
lcat04666  Fc gamma R-mediated phagocytosis
lcat04670  Leukocyte transendothelial migration
lcat04722  Neurotrophin signaling pathway
lcat04810  Regulation of actin cytoskeleton
lcat04932  Non-alcoholic fatty liver disease
lcat04933  AGE-RAGE signaling pathway in diabetic complications
lcat04972  Pancreatic secretion
lcat05014  Amyotrophic lateral sclerosis
lcat05020  Prion disease
lcat05022  Pathways of neurodegeneration - multiple diseases
lcat05100  Bacterial invasion of epithelial cells
lcat05132  Salmonella infection
lcat05135  Yersinia infection
lcat05163  Human cytomegalovirus infection
lcat05167  Kaposi sarcoma-associated herpesvirus infection
lcat05169  Epstein-Barr virus infection
lcat05170  Human immunodeficiency virus 1 infection
lcat05200  Pathways in cancer
lcat05203  Viral carcinogenesis
lcat05205  Proteoglycans in cancer
lcat05208  Chemical carcinogenesis - reactive oxygen species
lcat05210  Colorectal cancer
lcat05211  Renal cell carcinoma
lcat05212  Pancreatic cancer
lcat05231  Choline metabolism in cancer
lcat05415  Diabetic cardiomyopathy
lcat05416  Viral myocarditis
lcat05417  Lipid and atherosclerosis
lcat05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:lcat00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    123631548 (RAC1)
   04014 Ras signaling pathway
    123631548 (RAC1)
   04015 Rap1 signaling pathway
    123631548 (RAC1)
   04310 Wnt signaling pathway
    123631548 (RAC1)
   04370 VEGF signaling pathway
    123631548 (RAC1)
   04071 Sphingolipid signaling pathway
    123631548 (RAC1)
   04024 cAMP signaling pathway
    123631548 (RAC1)
   04151 PI3K-Akt signaling pathway
    123631548 (RAC1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    123631548 (RAC1)
   04148 Efferocytosis
    123631548 (RAC1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    123631548 (RAC1)
   04520 Adherens junction
    123631548 (RAC1)
   04530 Tight junction
    123631548 (RAC1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    123631548 (RAC1)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    123631548 (RAC1)
   04620 Toll-like receptor signaling pathway
    123631548 (RAC1)
   04650 Natural killer cell mediated cytotoxicity
    123631548 (RAC1)
   04662 B cell receptor signaling pathway
    123631548 (RAC1)
   04664 Fc epsilon RI signaling pathway
    123631548 (RAC1)
   04666 Fc gamma R-mediated phagocytosis
    123631548 (RAC1)
   04670 Leukocyte transendothelial migration
    123631548 (RAC1)
   04062 Chemokine signaling pathway
    123631548 (RAC1)
  09154 Digestive system
   04972 Pancreatic secretion
    123631548 (RAC1)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    123631548 (RAC1)
  09158 Development and regeneration
   04360 Axon guidance
    123631548 (RAC1)
   04380 Osteoclast differentiation
    123631548 (RAC1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    123631548 (RAC1)
   05205 Proteoglycans in cancer
    123631548 (RAC1)
   05208 Chemical carcinogenesis - reactive oxygen species
    123631548 (RAC1)
   05203 Viral carcinogenesis
    123631548 (RAC1)
   05231 Choline metabolism in cancer
    123631548 (RAC1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    123631548 (RAC1)
   05212 Pancreatic cancer
    123631548 (RAC1)
   05211 Renal cell carcinoma
    123631548 (RAC1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    123631548 (RAC1)
   05163 Human cytomegalovirus infection
    123631548 (RAC1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    123631548 (RAC1)
   05169 Epstein-Barr virus infection
    123631548 (RAC1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    123631548 (RAC1)
   05135 Yersinia infection
    123631548 (RAC1)
   05100 Bacterial invasion of epithelial cells
    123631548 (RAC1)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    123631548 (RAC1)
   05020 Prion disease
    123631548 (RAC1)
   05022 Pathways of neurodegeneration - multiple diseases
    123631548 (RAC1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    123631548 (RAC1)
   05418 Fluid shear stress and atherosclerosis
    123631548 (RAC1)
   05415 Diabetic cardiomyopathy
    123631548 (RAC1)
   05416 Viral myocarditis
    123631548 (RAC1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    123631548 (RAC1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    123631548 (RAC1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:lcat04131]
    123631548 (RAC1)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:lcat04147]
    123631548 (RAC1)
   04031 GTP-binding proteins [BR:lcat04031]
    123631548 (RAC1)
Membrane trafficking [BR:lcat04131]
 Exocytosis
  Small GTPases and associated proteins
   Rho GTPases
    123631548 (RAC1)
 Endocytosis
  Lipid raft mediated endocytosis
   Arf6-dependent endocytosis
    123631548 (RAC1)
  Macropinocytosis
   Ras GTPases
    123631548 (RAC1)
 Others
  NADPH oxidases (Nox) and associated proteins
   Nox associated proteins
    123631548 (RAC1)
Exosome [BR:lcat04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   123631548 (RAC1)
  Exosomal proteins of other body fluids (saliva and urine)
   123631548 (RAC1)
  Exosomal proteins of colorectal cancer cells
   123631548 (RAC1)
  Exosomal proteins of bladder cancer cells
   123631548 (RAC1)
GTP-binding proteins [BR:lcat04031]
 Small (monomeric) G-proteins
  Rho Family
   Rac/Cdc42 [OT]
    123631548 (RAC1)
SSDB
Motif
Pfam: Ras Roc Arf GTP_EFTU CagD
Other DBs
NCBI-GeneID: 123631548
NCBI-ProteinID: XP_045397261
LinkDB
Position
2:complement(23391459..23412633)
AA seq 192 aa
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG
QEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLR
DDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPP
PVKKRKRKCLLL
NT seq 579 nt   +upstreamnt  +downstreamnt
atgcaggccatcaagtgtgtggtggtcggagacggagctgtaggtaaaacttgcctactg
atcagttatacaaccaatgcatttcctggagaatatatccctactgtctttgacaattat
tctgccaatgttatggtagatggaaaaccggtgaatctgggcttatgggatacggctgga
caagaagattatgacagattacgccccctatcctatccacagacagatgtattcttaatt
tgcttttcccttgtgagtcctgcatcatttgaaaatgtccgagcaaagtggtatcctgaa
gtgcgacaccattgtcccaacactcccatcatccttgtgggaaccaaacttgatcttagg
gatgataaggacacgattgagaaactgaaggagaagaagctgactcccatcacctatccg
cagggtttagccatggctaaagagatcggtgctgtaaaatacctggagtgctcggctctc
acacagcgaggcctcaagacagtgtttgacgaagctatccgagcagttctctgcccacca
cctgtcaagaagaggaagagaaaatgcctgctgttgtaa

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