KEGG   Lemur catta (Ring-tailed lemur): 123632869
Entry
123632869         CDS       T08326                                 
Symbol
MAPK14
Name
(RefSeq) mitogen-activated protein kinase 14 isoform X1
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
lcat  Lemur catta (Ring-tailed lemur)
Pathway
lcat01522  Endocrine resistance
lcat04010  MAPK signaling pathway
lcat04015  Rap1 signaling pathway
lcat04068  FoxO signaling pathway
lcat04071  Sphingolipid signaling pathway
lcat04114  Oocyte meiosis
lcat04148  Efferocytosis
lcat04218  Cellular senescence
lcat04261  Adrenergic signaling in cardiomyocytes
lcat04370  VEGF signaling pathway
lcat04380  Osteoclast differentiation
lcat04517  IgSF CAM signaling
lcat04550  Signaling pathways regulating pluripotency of stem cells
lcat04611  Platelet activation
lcat04613  Neutrophil extracellular trap formation
lcat04620  Toll-like receptor signaling pathway
lcat04621  NOD-like receptor signaling pathway
lcat04622  RIG-I-like receptor signaling pathway
lcat04625  C-type lectin receptor signaling pathway
lcat04657  IL-17 signaling pathway
lcat04658  Th1 and Th2 cell differentiation
lcat04659  Th17 cell differentiation
lcat04660  T cell receptor signaling pathway
lcat04664  Fc epsilon RI signaling pathway
lcat04668  TNF signaling pathway
lcat04670  Leukocyte transendothelial migration
lcat04714  Thermogenesis
lcat04722  Neurotrophin signaling pathway
lcat04723  Retrograde endocannabinoid signaling
lcat04728  Dopaminergic synapse
lcat04750  Inflammatory mediator regulation of TRP channels
lcat04912  GnRH signaling pathway
lcat04914  Progesterone-mediated oocyte maturation
lcat04917  Prolactin signaling pathway
lcat04926  Relaxin signaling pathway
lcat04932  Non-alcoholic fatty liver disease
lcat04933  AGE-RAGE signaling pathway in diabetic complications
lcat04935  Growth hormone synthesis, secretion and action
lcat04936  Alcoholic liver disease
lcat05014  Amyotrophic lateral sclerosis
lcat05020  Prion disease
lcat05022  Pathways of neurodegeneration - multiple diseases
lcat05132  Salmonella infection
lcat05133  Pertussis
lcat05135  Yersinia infection
lcat05140  Leishmaniasis
lcat05142  Chagas disease
lcat05145  Toxoplasmosis
lcat05152  Tuberculosis
lcat05161  Hepatitis B
lcat05163  Human cytomegalovirus infection
lcat05167  Kaposi sarcoma-associated herpesvirus infection
lcat05169  Epstein-Barr virus infection
lcat05170  Human immunodeficiency virus 1 infection
lcat05171  Coronavirus disease - COVID-19
lcat05205  Proteoglycans in cancer
lcat05208  Chemical carcinogenesis - reactive oxygen species
lcat05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
lcat05415  Diabetic cardiomyopathy
lcat05417  Lipid and atherosclerosis
lcat05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:lcat00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    123632869 (MAPK14)
   04015 Rap1 signaling pathway
    123632869 (MAPK14)
   04370 VEGF signaling pathway
    123632869 (MAPK14)
   04668 TNF signaling pathway
    123632869 (MAPK14)
   04068 FoxO signaling pathway
    123632869 (MAPK14)
   04071 Sphingolipid signaling pathway
    123632869 (MAPK14)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    123632869 (MAPK14)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    123632869 (MAPK14)
  09143 Cell growth and death
   04114 Oocyte meiosis
    123632869 (MAPK14)
   04218 Cellular senescence
    123632869 (MAPK14)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    123632869 (MAPK14)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    123632869 (MAPK14)
   04613 Neutrophil extracellular trap formation
    123632869 (MAPK14)
   04620 Toll-like receptor signaling pathway
    123632869 (MAPK14)
   04621 NOD-like receptor signaling pathway
    123632869 (MAPK14)
   04622 RIG-I-like receptor signaling pathway
    123632869 (MAPK14)
   04625 C-type lectin receptor signaling pathway
    123632869 (MAPK14)
   04660 T cell receptor signaling pathway
    123632869 (MAPK14)
   04658 Th1 and Th2 cell differentiation
    123632869 (MAPK14)
   04659 Th17 cell differentiation
    123632869 (MAPK14)
   04657 IL-17 signaling pathway
    123632869 (MAPK14)
   04664 Fc epsilon RI signaling pathway
    123632869 (MAPK14)
   04670 Leukocyte transendothelial migration
    123632869 (MAPK14)
  09152 Endocrine system
   04912 GnRH signaling pathway
    123632869 (MAPK14)
   04914 Progesterone-mediated oocyte maturation
    123632869 (MAPK14)
   04917 Prolactin signaling pathway
    123632869 (MAPK14)
   04926 Relaxin signaling pathway
    123632869 (MAPK14)
   04935 Growth hormone synthesis, secretion and action
    123632869 (MAPK14)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    123632869 (MAPK14)
  09156 Nervous system
   04728 Dopaminergic synapse
    123632869 (MAPK14)
   04723 Retrograde endocannabinoid signaling
    123632869 (MAPK14)
   04722 Neurotrophin signaling pathway
    123632869 (MAPK14)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    123632869 (MAPK14)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    123632869 (MAPK14)
  09159 Environmental adaptation
   04714 Thermogenesis
    123632869 (MAPK14)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    123632869 (MAPK14)
   05208 Chemical carcinogenesis - reactive oxygen species
    123632869 (MAPK14)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    123632869 (MAPK14)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    123632869 (MAPK14)
   05161 Hepatitis B
    123632869 (MAPK14)
   05171 Coronavirus disease - COVID-19
    123632869 (MAPK14)
   05163 Human cytomegalovirus infection
    123632869 (MAPK14)
   05167 Kaposi sarcoma-associated herpesvirus infection
    123632869 (MAPK14)
   05169 Epstein-Barr virus infection
    123632869 (MAPK14)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    123632869 (MAPK14)
   05135 Yersinia infection
    123632869 (MAPK14)
   05133 Pertussis
    123632869 (MAPK14)
   05152 Tuberculosis
    123632869 (MAPK14)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    123632869 (MAPK14)
   05140 Leishmaniasis
    123632869 (MAPK14)
   05142 Chagas disease
    123632869 (MAPK14)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    123632869 (MAPK14)
   05020 Prion disease
    123632869 (MAPK14)
   05022 Pathways of neurodegeneration - multiple diseases
    123632869 (MAPK14)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    123632869 (MAPK14)
   05418 Fluid shear stress and atherosclerosis
    123632869 (MAPK14)
   05415 Diabetic cardiomyopathy
    123632869 (MAPK14)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    123632869 (MAPK14)
   04932 Non-alcoholic fatty liver disease
    123632869 (MAPK14)
   04933 AGE-RAGE signaling pathway in diabetic complications
    123632869 (MAPK14)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    123632869 (MAPK14)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:lcat01001]
    123632869 (MAPK14)
Enzymes [BR:lcat01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     123632869 (MAPK14)
Protein kinases [BR:lcat01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   123632869 (MAPK14)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo APH NAD_binding_8
Other DBs
NCBI-GeneID: 123632869
NCBI-ProteinID: XP_045399552
LinkDB
Position
2:45637155..45710010
AA seq 360 aa
MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ
SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ
KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTG
TPPAYLINRMPSHEARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAA
QALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES
NT seq 1083 nt   +upstreamnt  +downstreamnt
atgtctcaggagaggcccacgttctaccggcaggagctgaacaagacaatctgggaggtg
cccgagcgttaccagaatctgtccccggtgggctccggcgcctatggctcggtgtgtgct
gcttttgacacaaaaactgggttacgtgtggcagtgaagaagctatccagaccatttcag
tccatcattcatgccaaaagaacctacagagaactgcggttacttaaacatatgaaacat
gaaaatgtgattggtctgttggacgtttttacacctgcaaggtctctggaggaattcaat
gatgtgtatctggtgacccatctcatgggggcagatctgaacaacattgtgaaatgtcag
aagcttaccgatgaccatgttcagttccttatctaccaaattctccgaggtctaaagtat
atacattcagctgacataattcacagggacctaaaacctagtaatctagctgtgaacgaa
gactgtgagctgaagatcctggactttggactggctcggcatacagatgatgaaatgaca
ggctacgtggccactaggtggtacagggcacctgagatcatgctgaactggatgcattac
aaccagacagttgatatttggtcagtgggatgcataatggcggagctgttgactggaaga
acattgtttcctggtacagaccatattaaccagcttcagcagattatgcgtctgacgggg
acaccccctgcttatctcattaacaggatgccaagccatgaggcaagaaactatattcag
tctttgacccagatgccgaagatgaactttgcaaacgtatttattggtgccaatcctttg
gctgtcgacttgctggagaagatgcttgtactggactcagataagagaattacagcagcc
caagccctcgcacatgcctactttgctcagtaccatgaccctgatgatgagccagtggcc
gacccttacgatcagtcctttgaaagcagggaccttctcatagatgagtggaaaagcctg
acctacgatgaagtcatcagctttgtgccgccaccccttgaccaagaagagatggagtcc
tga

DBGET integrated database retrieval system