KEGG   Lemur catta (Ring-tailed lemur): 123635081
Entry
123635081         CDS       T08326                                 
Symbol
NRAS
Name
(RefSeq) GTPase NRas
  KO
K07828  GTPase NRas
Organism
lcat  Lemur catta (Ring-tailed lemur)
Pathway
lcat01521  EGFR tyrosine kinase inhibitor resistance
lcat01522  Endocrine resistance
lcat04010  MAPK signaling pathway
lcat04012  ErbB signaling pathway
lcat04014  Ras signaling pathway
lcat04015  Rap1 signaling pathway
lcat04062  Chemokine signaling pathway
lcat04068  FoxO signaling pathway
lcat04071  Sphingolipid signaling pathway
lcat04072  Phospholipase D signaling pathway
lcat04137  Mitophagy - animal
lcat04140  Autophagy - animal
lcat04150  mTOR signaling pathway
lcat04151  PI3K-Akt signaling pathway
lcat04210  Apoptosis
lcat04211  Longevity regulating pathway
lcat04213  Longevity regulating pathway - multiple species
lcat04218  Cellular senescence
lcat04360  Axon guidance
lcat04370  VEGF signaling pathway
lcat04371  Apelin signaling pathway
lcat04540  Gap junction
lcat04550  Signaling pathways regulating pluripotency of stem cells
lcat04625  C-type lectin receptor signaling pathway
lcat04650  Natural killer cell mediated cytotoxicity
lcat04660  T cell receptor signaling pathway
lcat04662  B cell receptor signaling pathway
lcat04664  Fc epsilon RI signaling pathway
lcat04714  Thermogenesis
lcat04720  Long-term potentiation
lcat04722  Neurotrophin signaling pathway
lcat04725  Cholinergic synapse
lcat04726  Serotonergic synapse
lcat04730  Long-term depression
lcat04810  Regulation of actin cytoskeleton
lcat04910  Insulin signaling pathway
lcat04912  GnRH signaling pathway
lcat04915  Estrogen signaling pathway
lcat04916  Melanogenesis
lcat04917  Prolactin signaling pathway
lcat04919  Thyroid hormone signaling pathway
lcat04921  Oxytocin signaling pathway
lcat04926  Relaxin signaling pathway
lcat04929  GnRH secretion
lcat04933  AGE-RAGE signaling pathway in diabetic complications
lcat04935  Growth hormone synthesis, secretion and action
lcat05010  Alzheimer disease
lcat05022  Pathways of neurodegeneration - multiple diseases
lcat05034  Alcoholism
lcat05160  Hepatitis C
lcat05161  Hepatitis B
lcat05163  Human cytomegalovirus infection
lcat05165  Human papillomavirus infection
lcat05166  Human T-cell leukemia virus 1 infection
lcat05167  Kaposi sarcoma-associated herpesvirus infection
lcat05170  Human immunodeficiency virus 1 infection
lcat05200  Pathways in cancer
lcat05203  Viral carcinogenesis
lcat05205  Proteoglycans in cancer
lcat05206  MicroRNAs in cancer
lcat05207  Chemical carcinogenesis - receptor activation
lcat05208  Chemical carcinogenesis - reactive oxygen species
lcat05210  Colorectal cancer
lcat05211  Renal cell carcinoma
lcat05213  Endometrial cancer
lcat05214  Glioma
lcat05215  Prostate cancer
lcat05216  Thyroid cancer
lcat05218  Melanoma
lcat05219  Bladder cancer
lcat05220  Chronic myeloid leukemia
lcat05221  Acute myeloid leukemia
lcat05223  Non-small cell lung cancer
lcat05224  Breast cancer
lcat05225  Hepatocellular carcinoma
lcat05226  Gastric cancer
lcat05230  Central carbon metabolism in cancer
lcat05231  Choline metabolism in cancer
lcat05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
lcat05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:lcat00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    123635081 (NRAS)
   04012 ErbB signaling pathway
    123635081 (NRAS)
   04014 Ras signaling pathway
    123635081 (NRAS)
   04015 Rap1 signaling pathway
    123635081 (NRAS)
   04370 VEGF signaling pathway
    123635081 (NRAS)
   04371 Apelin signaling pathway
    123635081 (NRAS)
   04068 FoxO signaling pathway
    123635081 (NRAS)
   04072 Phospholipase D signaling pathway
    123635081 (NRAS)
   04071 Sphingolipid signaling pathway
    123635081 (NRAS)
   04151 PI3K-Akt signaling pathway
    123635081 (NRAS)
   04150 mTOR signaling pathway
    123635081 (NRAS)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    123635081 (NRAS)
   04137 Mitophagy - animal
    123635081 (NRAS)
  09143 Cell growth and death
   04210 Apoptosis
    123635081 (NRAS)
   04218 Cellular senescence
    123635081 (NRAS)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    123635081 (NRAS)
   04550 Signaling pathways regulating pluripotency of stem cells
    123635081 (NRAS)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    123635081 (NRAS)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    123635081 (NRAS)
   04650 Natural killer cell mediated cytotoxicity
    123635081 (NRAS)
   04660 T cell receptor signaling pathway
    123635081 (NRAS)
   04662 B cell receptor signaling pathway
    123635081 (NRAS)
   04664 Fc epsilon RI signaling pathway
    123635081 (NRAS)
   04062 Chemokine signaling pathway
    123635081 (NRAS)
  09152 Endocrine system
   04910 Insulin signaling pathway
    123635081 (NRAS)
   04929 GnRH secretion
    123635081 (NRAS)
   04912 GnRH signaling pathway
    123635081 (NRAS)
   04915 Estrogen signaling pathway
    123635081 (NRAS)
   04917 Prolactin signaling pathway
    123635081 (NRAS)
   04921 Oxytocin signaling pathway
    123635081 (NRAS)
   04926 Relaxin signaling pathway
    123635081 (NRAS)
   04935 Growth hormone synthesis, secretion and action
    123635081 (NRAS)
   04919 Thyroid hormone signaling pathway
    123635081 (NRAS)
   04916 Melanogenesis
    123635081 (NRAS)
  09156 Nervous system
   04725 Cholinergic synapse
    123635081 (NRAS)
   04726 Serotonergic synapse
    123635081 (NRAS)
   04720 Long-term potentiation
    123635081 (NRAS)
   04730 Long-term depression
    123635081 (NRAS)
   04722 Neurotrophin signaling pathway
    123635081 (NRAS)
  09158 Development and regeneration
   04360 Axon guidance
    123635081 (NRAS)
  09149 Aging
   04211 Longevity regulating pathway
    123635081 (NRAS)
   04213 Longevity regulating pathway - multiple species
    123635081 (NRAS)
  09159 Environmental adaptation
   04714 Thermogenesis
    123635081 (NRAS)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    123635081 (NRAS)
   05206 MicroRNAs in cancer
    123635081 (NRAS)
   05205 Proteoglycans in cancer
    123635081 (NRAS)
   05207 Chemical carcinogenesis - receptor activation
    123635081 (NRAS)
   05208 Chemical carcinogenesis - reactive oxygen species
    123635081 (NRAS)
   05203 Viral carcinogenesis
    123635081 (NRAS)
   05230 Central carbon metabolism in cancer
    123635081 (NRAS)
   05231 Choline metabolism in cancer
    123635081 (NRAS)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    123635081 (NRAS)
  09162 Cancer: specific types
   05210 Colorectal cancer
    123635081 (NRAS)
   05225 Hepatocellular carcinoma
    123635081 (NRAS)
   05226 Gastric cancer
    123635081 (NRAS)
   05214 Glioma
    123635081 (NRAS)
   05216 Thyroid cancer
    123635081 (NRAS)
   05221 Acute myeloid leukemia
    123635081 (NRAS)
   05220 Chronic myeloid leukemia
    123635081 (NRAS)
   05218 Melanoma
    123635081 (NRAS)
   05211 Renal cell carcinoma
    123635081 (NRAS)
   05219 Bladder cancer
    123635081 (NRAS)
   05215 Prostate cancer
    123635081 (NRAS)
   05213 Endometrial cancer
    123635081 (NRAS)
   05224 Breast cancer
    123635081 (NRAS)
   05223 Non-small cell lung cancer
    123635081 (NRAS)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    123635081 (NRAS)
   05170 Human immunodeficiency virus 1 infection
    123635081 (NRAS)
   05161 Hepatitis B
    123635081 (NRAS)
   05160 Hepatitis C
    123635081 (NRAS)
   05163 Human cytomegalovirus infection
    123635081 (NRAS)
   05167 Kaposi sarcoma-associated herpesvirus infection
    123635081 (NRAS)
   05165 Human papillomavirus infection
    123635081 (NRAS)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    123635081 (NRAS)
   05022 Pathways of neurodegeneration - multiple diseases
    123635081 (NRAS)
  09165 Substance dependence
   05034 Alcoholism
    123635081 (NRAS)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    123635081 (NRAS)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    123635081 (NRAS)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    123635081 (NRAS)
   01522 Endocrine resistance
    123635081 (NRAS)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:lcat04131]
    123635081 (NRAS)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:lcat04147]
    123635081 (NRAS)
   04031 GTP-binding proteins [BR:lcat04031]
    123635081 (NRAS)
Membrane trafficking [BR:lcat04131]
 Exocytosis
  Small GTPases and associated proteins
   Other small GTPases and associated proteins
    123635081 (NRAS)
 Endocytosis
  Macropinocytosis
   Ras GTPases
    123635081 (NRAS)
Exosome [BR:lcat04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   123635081 (NRAS)
  Exosomal proteins of other body fluids (saliva and urine)
   123635081 (NRAS)
  Exosomal proteins of breast cancer cells
   123635081 (NRAS)
  Exosomal proteins of colorectal cancer cells
   123635081 (NRAS)
GTP-binding proteins [BR:lcat04031]
 Small (monomeric) G-proteins
  Ras Family
   Ras [OT]
    123635081 (NRAS)
SSDB
Motif
Pfam: Ras Roc Arf GTP_EFTU MMR_HSR1 RsgA_GTPase FeoB_N Septin Ldh_1_N ParA
Other DBs
NCBI-GeneID: 123635081
NCBI-ProteinID: XP_045402841
LinkDB
Position
3:complement(18464359..18474633)
AA seq 189 aa
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
QEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDL
PTRTVDTKQAHELAKSYGIPFIETSAKTRQGVEDAFYTLVREIRQYRMKKLNSSDDGTQG
CMGLPCVVM
NT seq 570 nt   +upstreamnt  +downstreamnt
atgactgagtacaaactggtggtggttggagcaggtggtgttgggaaaagcgcactgaca
atccagctaatccagaaccactttgtagatgaatatgatcccaccatagaggattcttac
cgaaaacaggtggttatagatggtgaaacctgtctgttggacatactggatacagctgga
caagaggagtacagtgccatgagagaccaatacatgaggacaggcgaaggcttcctctgt
gtatttgccatcaataatagcaagtcatttgcagatattaacctctacagggagcagatt
aaacgagtaaaggattcagatgatgtacctatggtgctggtaggaaacaagtgtgatttg
ccaacaaggacagttgacacaaaacaagcccacgagctggccaagagttacgggattcca
tttattgaaacctcagccaagaccagacagggtgtcgaagatgccttttacacactggta
agagaaatacgccagtaccgaatgaaaaaactcaacagcagtgatgatgggactcaaggt
tgtatggggttgccatgtgtggtgatgtaa

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