KEGG   Lemur catta (Ring-tailed lemur): 123640339
Entry
123640339         CDS       T08326                                 
Symbol
ATF4
Name
(RefSeq) cyclic AMP-dependent transcription factor ATF-4
  KO
K04374  cyclic AMP-dependent transcription factor ATF-4
Organism
lcat  Lemur catta (Ring-tailed lemur)
Pathway
lcat04010  MAPK signaling pathway
lcat04022  cGMP-PKG signaling pathway
lcat04137  Mitophagy - animal
lcat04141  Protein processing in endoplasmic reticulum
lcat04151  PI3K-Akt signaling pathway
lcat04210  Apoptosis
lcat04211  Longevity regulating pathway
lcat04261  Adrenergic signaling in cardiomyocytes
lcat04668  TNF signaling pathway
lcat04720  Long-term potentiation
lcat04722  Neurotrophin signaling pathway
lcat04725  Cholinergic synapse
lcat04728  Dopaminergic synapse
lcat04911  Insulin secretion
lcat04912  GnRH signaling pathway
lcat04915  Estrogen signaling pathway
lcat04918  Thyroid hormone synthesis
lcat04922  Glucagon signaling pathway
lcat04925  Aldosterone synthesis and secretion
lcat04926  Relaxin signaling pathway
lcat04927  Cortisol synthesis and secretion
lcat04928  Parathyroid hormone synthesis, secretion and action
lcat04932  Non-alcoholic fatty liver disease
lcat04934  Cushing syndrome
lcat04935  Growth hormone synthesis, secretion and action
lcat05010  Alzheimer disease
lcat05012  Parkinson disease
lcat05014  Amyotrophic lateral sclerosis
lcat05020  Prion disease
lcat05022  Pathways of neurodegeneration - multiple diseases
lcat05030  Cocaine addiction
lcat05031  Amphetamine addiction
lcat05034  Alcoholism
lcat05161  Hepatitis B
lcat05163  Human cytomegalovirus infection
lcat05166  Human T-cell leukemia virus 1 infection
lcat05203  Viral carcinogenesis
lcat05207  Chemical carcinogenesis - receptor activation
lcat05215  Prostate cancer
lcat05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:lcat00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    123640339 (ATF4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    123640339 (ATF4)
   04668 TNF signaling pathway
    123640339 (ATF4)
   04022 cGMP-PKG signaling pathway
    123640339 (ATF4)
   04151 PI3K-Akt signaling pathway
    123640339 (ATF4)
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    123640339 (ATF4)
  09143 Cell growth and death
   04210 Apoptosis
    123640339 (ATF4)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    123640339 (ATF4)
   04922 Glucagon signaling pathway
    123640339 (ATF4)
   04912 GnRH signaling pathway
    123640339 (ATF4)
   04915 Estrogen signaling pathway
    123640339 (ATF4)
   04926 Relaxin signaling pathway
    123640339 (ATF4)
   04935 Growth hormone synthesis, secretion and action
    123640339 (ATF4)
   04918 Thyroid hormone synthesis
    123640339 (ATF4)
   04928 Parathyroid hormone synthesis, secretion and action
    123640339 (ATF4)
   04925 Aldosterone synthesis and secretion
    123640339 (ATF4)
   04927 Cortisol synthesis and secretion
    123640339 (ATF4)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    123640339 (ATF4)
  09156 Nervous system
   04725 Cholinergic synapse
    123640339 (ATF4)
   04728 Dopaminergic synapse
    123640339 (ATF4)
   04720 Long-term potentiation
    123640339 (ATF4)
   04722 Neurotrophin signaling pathway
    123640339 (ATF4)
  09149 Aging
   04211 Longevity regulating pathway
    123640339 (ATF4)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    123640339 (ATF4)
   05203 Viral carcinogenesis
    123640339 (ATF4)
  09162 Cancer: specific types
   05215 Prostate cancer
    123640339 (ATF4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    123640339 (ATF4)
   05161 Hepatitis B
    123640339 (ATF4)
   05163 Human cytomegalovirus infection
    123640339 (ATF4)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    123640339 (ATF4)
   05012 Parkinson disease
    123640339 (ATF4)
   05014 Amyotrophic lateral sclerosis
    123640339 (ATF4)
   05020 Prion disease
    123640339 (ATF4)
   05022 Pathways of neurodegeneration - multiple diseases
    123640339 (ATF4)
  09165 Substance dependence
   05030 Cocaine addiction
    123640339 (ATF4)
   05031 Amphetamine addiction
    123640339 (ATF4)
   05034 Alcoholism
    123640339 (ATF4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    123640339 (ATF4)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    123640339 (ATF4)
   04934 Cushing syndrome
    123640339 (ATF4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:lcat03000]
    123640339 (ATF4)
Transcription factors [BR:lcat03000]
 Eukaryotic type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, CRE-BP/ATF
    123640339 (ATF4)
SSDB
Motif
Pfam: bZIP_1 bZIP_2 KIF21A bZIP_Maf OVT1 DUF4407 Asd-4 ERM_helical
Other DBs
NCBI-GeneID: 123640339
NCBI-ProteinID: XP_045410824
LinkDB
Position
6:complement(8429221..8431457)
AA seq 351 aa
MTEMSFLSSEVLGGDLMSPFDQSGLGAEESLDLLDDYLEVAKHFKPHGFSSDKAKAGSSG
WLAVDGLVSASNNGKEDAFSGTDWMLEKMDLKEFDFDALLNLDDLETMPDELLATLDDTG
DLFAPLVQQTNKEPPQTVNPIGHLPESLTKADQVAPFTFLQPLPLLPGVLSSTPDHSFSL
ELGSEVDISEGDRKSDSSAYITLIPQCVKEEDTPSDNDSGVCMSPESYLGSPQHSPSTAS
GSPNSLPSPGVLCGSARPKPYNRPGEKMVVAKVKGEKLDKKLKKMEQNKTAATRYRQKKR
AEQEALAGECKELEKKNESLKEKADALAKEIQYLKDLIEEVRKARGKKRVS
NT seq 1056 nt   +upstreamnt  +downstreamnt
atgaccgagatgagcttcctgagcagcgaggtgttggggggggacttgatgtcccccttc
gaccagtcgggtttgggggctgaagaaagtctagatctcttagatgattacctggaggtg
gccaagcacttcaaacctcatgggttctccagcgacaaggctaaggcgggctcctccgga
tggctggctgtggatgggttggtcagtgcctccaacaatggcaaggaggatgccttctcg
gggacagattggatgttggagaaaatggatttgaaggagtttgactttgatgccctgttg
aatttagatgacctggaaaccatgccagatgagcttttggccacgttggatgacacgggt
gatctctttgcccccctagtccagcagactaataaggagcccccccagacagtgaaccca
attggccatctcccagaaagtttaacaaaagctgaccaggttgcccctttcaccttcctg
cagcctcttccccttctcccaggggtcctgtcctccactccagatcattcctttagttta
gagctgggcagtgaagtggatatctctgaaggagataggaagtcagactccagtgcttac
attaccctgattcctcagtgtgtaaaggaggaagacaccccctcagataatgacagtggt
gtctgtatgagccctgagtcctatctgggctctccccagcatagcccttctaccgccagt
ggctctccaaacagcctgccatctccaggtgtcctctgtggctctgcccgccccaaaccg
tacaatcgtcctggagagaagatggtagtagcaaaagtaaagggtgagaagctggataag
aagctgaaaaaaatggagcaaaacaagactgcggccactagatatcgccagaagaagagg
gcagagcaggaagcccttgctggcgagtgcaaagagctggagaagaagaatgagtctctg
aaagagaaggcggatgccctggccaaggagatccaatacctgaaagatttgattgaagag
gtccgcaaggcaagggggaaaaaaagggtctcctag

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