KEGG   Lemur catta (Ring-tailed lemur): 123642855
Entry
123642855         CDS       T08326                                 
Symbol
PPP1CA
Name
(RefSeq) serine/threonine-protein phosphatase PP1-alpha catalytic subunit
  KO
K06269  serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
Organism
lcat  Lemur catta (Ring-tailed lemur)
Pathway
lcat03015  mRNA surveillance pathway
lcat04022  cGMP-PKG signaling pathway
lcat04024  cAMP signaling pathway
lcat04114  Oocyte meiosis
lcat04218  Cellular senescence
lcat04261  Adrenergic signaling in cardiomyocytes
lcat04270  Vascular smooth muscle contraction
lcat04390  Hippo signaling pathway
lcat04510  Focal adhesion
lcat04611  Platelet activation
lcat04720  Long-term potentiation
lcat04728  Dopaminergic synapse
lcat04750  Inflammatory mediator regulation of TRP channels
lcat04810  Regulation of actin cytoskeleton
lcat04910  Insulin signaling pathway
lcat04921  Oxytocin signaling pathway
lcat04931  Insulin resistance
lcat05031  Amphetamine addiction
lcat05034  Alcoholism
lcat05168  Herpes simplex virus 1 infection
lcat05205  Proteoglycans in cancer
lcat05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:lcat00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    123642855 (PPP1CA)
 09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    123642855 (PPP1CA)
   04024 cAMP signaling pathway
    123642855 (PPP1CA)
   04022 cGMP-PKG signaling pathway
    123642855 (PPP1CA)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    123642855 (PPP1CA)
   04218 Cellular senescence
    123642855 (PPP1CA)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    123642855 (PPP1CA)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    123642855 (PPP1CA)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    123642855 (PPP1CA)
  09152 Endocrine system
   04910 Insulin signaling pathway
    123642855 (PPP1CA)
   04921 Oxytocin signaling pathway
    123642855 (PPP1CA)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    123642855 (PPP1CA)
   04270 Vascular smooth muscle contraction
    123642855 (PPP1CA)
  09156 Nervous system
   04728 Dopaminergic synapse
    123642855 (PPP1CA)
   04720 Long-term potentiation
    123642855 (PPP1CA)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    123642855 (PPP1CA)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    123642855 (PPP1CA)
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    123642855 (PPP1CA)
  09165 Substance dependence
   05031 Amphetamine addiction
    123642855 (PPP1CA)
   05034 Alcoholism
    123642855 (PPP1CA)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    123642855 (PPP1CA)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    123642855 (PPP1CA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:lcat01009]
    123642855 (PPP1CA)
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:lcat03021]
    123642855 (PPP1CA)
   03019 Messenger RNA biogenesis [BR:lcat03019]
    123642855 (PPP1CA)
   03041 Spliceosome [BR:lcat03041]
    123642855 (PPP1CA)
Enzymes [BR:lcat01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     123642855 (PPP1CA)
Protein phosphatases and associated proteins [BR:lcat01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    Catalytic subunits
     123642855 (PPP1CA)
Transcription machinery [BR:lcat03021]
 Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Transcription termination factor
     123642855 (PPP1CA)
Messenger RNA biogenesis [BR:lcat03019]
 Eukaryotic type
  mRNA processing factors
   3' end processing
    Cleavage and polyadenylation specificity factor (CPSF) complex
     123642855 (PPP1CA)
Spliceosome [BR:lcat03041]
 Other splicing related proteins
  Spliceosome associated proteins (SAPs)
   Other SAPs
    123642855 (PPP1CA)
SSDB
Motif
Pfam: Metallophos STPPase_N
Other DBs
NCBI-GeneID: 123642855
NCBI-ProteinID: XP_045414308
LinkDB
Position
7:104831867..104835202
AA seq 330 aa
MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLK
ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL
LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL
QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHD
LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAD
KNKGKYGQFSGLNPGGRPITPPRNSAKAKK
NT seq 993 nt   +upstreamnt  +downstreamnt
atgtccgacagcgagaagctcaacctggactctatcatcgggcgcctgctggaagtgcag
ggctcacggcctggaaagaatgtacagctgacagaaaatgagatccgtggtctgtgcctc
aaatcccgggagattttcctgagccagcccattcttttggagctggaggcacccctcaag
atctgcggtgacatccatggccagtactatgaccttctgcggctgtttgagtatggcggc
ttccctccagagagcaactacctcttcctgggggactatgtggaccggggcaagcagtct
ctggagactatctgcctgctgctggcctataagatcaagtaccctgagaatttcttcctg
ctccgtgggaaccatgagtgtgccagcatcaaccgtatctacggtttctacgatgagtgt
aagagacgctacaacatcaaactgtggaaaaccttcactgactgcttcaattgcctgccc
atcgcagccattgtagatgagaagatcttctgctgccacggaggcctgtccccggacctg
cagtccatggagcagatacgacgcatcatgcggcccacagatgtgcctgaccagggcctg
ctgtgtgacctgctgtggtctgaccctgacaaggatgtgcagggctggggtgagaacgac
cgtggcgtctcctttaccttcggagctgaggtggttgccaagttcctgcacaagcacgac
ttggacctcatctgccgagcgcaccaggtagtagaagatggctatgagttctttgccaaa
cggcagctggtgacacttttctcagctcccaactactgtggcgagtttgacaacgctggt
gccatgatgagtgtggatgagaccctcatgtgctccttccagatcctcaagcccgctgac
aagaacaaggggaaatacgggcagttcagtggcctgaaccccgggggccgacctatcacc
ccaccccgcaattctgccaaagccaagaaatag

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