Lemur catta (Ring-tailed lemur): 123644088
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Entry
123644088 CDS
T08326
Symbol
NDUFS1
Name
(RefSeq) NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
KO
K03934
NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:
7.1.1.2
]
Organism
lcat
Lemur catta (Ring-tailed lemur)
Pathway
lcat00190
Oxidative phosphorylation
lcat01100
Metabolic pathways
lcat04714
Thermogenesis
lcat04723
Retrograde endocannabinoid signaling
lcat04932
Non-alcoholic fatty liver disease
lcat05010
Alzheimer disease
lcat05012
Parkinson disease
lcat05014
Amyotrophic lateral sclerosis
lcat05016
Huntington disease
lcat05020
Prion disease
lcat05022
Pathways of neurodegeneration - multiple diseases
lcat05208
Chemical carcinogenesis - reactive oxygen species
lcat05415
Diabetic cardiomyopathy
Module
lcat_M00143
NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria
Brite
KEGG Orthology (KO) [BR:
lcat00001
]
09100 Metabolism
09102 Energy metabolism
00190 Oxidative phosphorylation
123644088 (NDUFS1)
09150 Organismal Systems
09156 Nervous system
04723 Retrograde endocannabinoid signaling
123644088 (NDUFS1)
09159 Environmental adaptation
04714 Thermogenesis
123644088 (NDUFS1)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
123644088 (NDUFS1)
09164 Neurodegenerative disease
05010 Alzheimer disease
123644088 (NDUFS1)
05012 Parkinson disease
123644088 (NDUFS1)
05014 Amyotrophic lateral sclerosis
123644088 (NDUFS1)
05016 Huntington disease
123644088 (NDUFS1)
05020 Prion disease
123644088 (NDUFS1)
05022 Pathways of neurodegeneration - multiple diseases
123644088 (NDUFS1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
123644088 (NDUFS1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
123644088 (NDUFS1)
Enzymes [BR:
lcat01000
]
7. Translocases
7.1 Catalysing the translocation of protons
7.1.1 Linked to oxidoreductase reactions
7.1.1.2 NADH:ubiquinone reductase (H+-translocating)
123644088 (NDUFS1)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Molybdopterin
Fer4_Nqo3
Fer4_NDSU1
Fer2_4
NADH-G_4Fe-4S_3
NADH_dhqG_C
Fer2
Motif
Other DBs
NCBI-GeneID:
123644088
NCBI-ProteinID:
XP_045416219
LinkDB
All DBs
Position
8:26766830..26807054
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AA seq
727 aa
AA seq
DB search
MLRIPVRRALIGLSKSPKGCVRTAATAASNLIEVFVDGQSVMVEPGTTVLQACEKVGMQI
PRFCYHERLSVAGNCRMCLVEIEKAPKVVAACAMPVMKGWNILTNSEKSKKAREGVMEFL
LANHPLDCPICDQGGECDLQDQSMMFGSDRSRFLEGKRAVEDKNIGPLVKTIMTRCIQCT
RCIRFASEIAGVDDLGTTGRGNDMQVGTYIEKMFMSELSGNIIDICPVGALTSKPYAFTA
RPWETRKTESIDVMDAVGSNIVVSTRTGEVMRILPRMHEDINEEWISDKTRFAYDGLKRQ
RLTEPMVRNEKGLLTYTSWEDALSRVAGMLQSFQGKDVAAIAGGLVDAEALVALKDLLNR
VDSDTLCTEEVFPTAGAGTDLRSNYLLNTTIAGMEEADVVLLVGTNPRFEAPLFNARIRK
SWLHNDLKVALIGSPVDLTYTYDHLGDSPKILQDIASDSHSFSQVLKEAKKPMVVLGSSA
LQRNDGAAILAAVSSIAQKIRMTSGVTEDWKVMNILHRIASQVAALDLGYKPGVEAIRKN
PPKVLFLLGADGGCITRQDLPKDCFIIYQGHHGDVGAPIADVILPGAAYTEKSATYVNTE
GRAQQTKVAVTPPGLAREDWKIIRALSEIVGITLPYDTLDQVRNRLEEVSPNLVRYDDVE
GANYFQQANELSKLVNQQLLADPLVPPQLTIKDFYMTDSISRASQTMAKCVKAVTEGAHA
VEEPSIC
NT seq
2184 nt
NT seq
+upstream
nt +downstream
nt
atgttaaggatacctgtaagaagggccttaataggcctttctaagtctcccaaaggatgt
gttcgaacagctgcaacagcagcaagcaacttgattgaagtgtttgttgatggtcagtct
gtcatggtggaaccaggaactactgtcctccaggcttgtgagaaagttggcatgcagatc
ccccgattctgttatcatgaaaggttgtctgttgctggaaactgcaggatgtgccttgtt
gaaattgagaaagctcctaaggttgtagctgcctgtgccatgccagtaatgaagggttgg
aatatcttgacaaactcagaaaaatccaagaaagccagagaaggtgtgatggagttctta
ttagcaaatcacccactggactgccctatttgtgaccagggaggtgaatgtgatctgcaa
gaccagtccatgatgtttggaagtgataggagtcgatttttagaaggaaaacgtgctgtg
gaggacaagaacattgggccattggtaaagaccatcatgactagatgtatacagtgcact
cgctgcatcaggtttgcaagtgagattgcaggagtagatgatttgggaactacaggcaga
ggaaatgatatgcaagttggcacctatattgaaaagatgttcatgtccgaactgtctggg
aatatcattgatatctgccctgtaggtgccctaacctctaagccttacgcctttactgcc
cggccttgggaaacaagaaagacagaatccattgatgtaatggatgcagtaggaagtaat
atcgtggttagcacaagaactggagaagtaatgagaatcttgccacgtatgcatgaagac
atcaatgaagagtggatctctgataaaaccagatttgcctatgatgggctaaaacgtcag
agacttacagagccgatggtcagaaacgaaaaggggcttttaacctatacctcctgggag
gatgcactctctcgtgtagctggaatgttgcagagttttcaaggcaaggatgtggcagca
attgcaggtggcctggtggatgctgaagccctagtagctctcaaagatttgcttaataga
gtggactctgacaccttatgcactgaagaggtcttccccactgcaggagctggcacagat
ttacgttccaattatcttcttaatactacaattgctggcatggaagaggctgatgttgtc
cttctggttggtacgaatccacgttttgaggcaccactatttaatgctagaattcgaaag
agctggcttcataatgacttaaaagtggcccttataggtagtccagtggacctcacttac
acatatgaccacctgggagactcccccaaaattctacaagacattgcttcggatagccat
tcatttagccaggtcctaaaggaagctaaaaaaccaatggtggttttaggcagttctgca
ctccaaagaaatgatggagcagcaattcttgcagctgtttccagcattgcacaaaagatt
cggatgactagtggtgttactgaagattggaaagttatgaatatccttcataggattgca
agtcaagtagctgctttggatcttggctataaacctggagtggaagcaattcgcaagaac
cctcccaaagtgctgtttctcctgggagcagatggaggttgtatcacacgacaggatttg
cccaaggattgttttattatttatcaaggacatcatggtgatgttggagcacccatagct
gatgttattctcccaggagctgcttatacagagaaatctgctacttatgtcaatacggag
ggcagagctcagcagactaaagtagcagtaacacctcccggcttggcaagagaagactgg
aaaattataagagccctgtctgagattgtgggtataactcttccatatgatactctggat
caagtgagaaacagattggaagaagtctctcctaatcttgttcgatatgatgatgttgaa
ggagctaattacttccagcaagcaaatgagctctccaagctagtgaaccagcaacttctt
gctgacccacttgttccacctcagctaactataaaagacttctacatgacagattcaatt
agcagagcctcacagacaatggccaagtgtgtcaaagctgtcacagagggtgcgcatgca
gtagaagagccatccatttgctga
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