Lemur catta (Ring-tailed lemur): 123645128
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Entry
123645128 CDS
T08326
Symbol
IDH2
Name
(RefSeq) isocitrate dehydrogenase [NADP], mitochondrial
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
lcat
Lemur catta (Ring-tailed lemur)
Pathway
lcat00020
Citrate cycle (TCA cycle)
lcat00480
Glutathione metabolism
lcat01100
Metabolic pathways
lcat01200
Carbon metabolism
lcat01210
2-Oxocarboxylic acid metabolism
lcat01230
Biosynthesis of amino acids
lcat04146
Peroxisome
lcat05230
Central carbon metabolism in cancer
Module
lcat_M00009
Citrate cycle (TCA cycle, Krebs cycle)
lcat_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
lcat00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
123645128 (IDH2)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
123645128 (IDH2)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
123645128 (IDH2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
123645128 (IDH2)
Enzymes [BR:
lcat01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
123645128 (IDH2)
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GFIT
Motif
Pfam:
Iso_dh
Motif
Other DBs
NCBI-GeneID:
123645128
NCBI-ProteinID:
XP_045417657
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Position
9:4934748..4949007
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AA seq
497 aa
AA seq
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MGGGAGGPAPAGSRPAPARPSCSPRPGAQGAARARISPARPPARLLGMAGYLRAARSLCR
APGPAWAPAALTAPAAREQPRRHYADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHV
DVQLKYFDLGLPNRDQTNDQVTIDSALATQKYHVAVKCATITPDEARVEEFKLKKMWKSP
NGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMV
FTPKDGSSAKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTIL
KAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKSAGGFVWACKNYDGDV
QSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAW
TRGLEHRGKLDGSQDLIRFAQTLEKVCVETVESGAMTKDLAGCIHGLSNVRLNEHFLNTT
DFLDTIKSNLDRALGKP
NT seq
1494 nt
NT seq
+upstream
nt +downstream
nt
atgggcggcggcgctggcggccccgccccggcggggtcccggccggcgcccgcccggccc
agctgcagcccgcggccaggcgcccagggagcggcccgcgctcggatctctcccgcccgc
ccgcccgctcgcctcctcgggatggccggctacctgcgggccgcgcgctcgctctgcaga
gccccgggcccggcctgggcgccggcggccctgacagcccccgccgcgcgggagcagccg
cggcgccactatgctgacaagaggatcaaagtagcaaagccagtggtggagatggacggt
gatgagatgacccggatcatctggcagttcatcaaggagaagctcatcctgccccacgtg
gacgtccagctcaagtattttgaccttgggctcccaaaccgtgaccagaccaacgaccag
gtcaccattgactctgcattggccacccagaagtaccacgtggctgtcaagtgtgccacc
atcacccccgatgaggcccgcgtggaagagttcaaactgaagaagatgtggaaaagtccc
aatggaaccatccggaacatccttggggggactgtcttccgggagcccatcatctgcaag
aacatcccacgcctcgtgcctggctggaccaagcctatcaccattggcaggcatgcccac
ggcgaccagtacaaggccacagacttcgtggcggatcgcgctggcacgttcaagatggtc
ttcaccccgaaggacggcagcagtgccaaggagtgggaggtgtacaacttccccgcgggc
ggcgtgggcatgggcatgtacaacaccgacgagtccatctcgggctttgcgcacagctgt
ttccagtatgccatccagaagaagtggccgctgtacatgagcaccaagaacacgattctg
aaagcctacgacgggcgtttcaaagacatcttccaggagatctttgacaagcattataag
acagacttcgacaagaataagatctggtatgagcaccggctcattgacgacatggtggct
caggtcctcaagtctgcgggcggcttcgtgtgggcttgcaagaactacgacggagacgtg
cagtcagatatcctggcccagggcttcggctccctgggcctgatgacatccgtgctggtc
tgcccggatgggaagaccattgaggccgaggcagctcacgggacggtcacccgccactat
cgggagcaccagaagggccggccaaccagcaccaaccccatcgccagcatcttcgcctgg
acgcgcggcctggagcaccggggcaagctggacgggagccaggacctcatcaggtttgcc
cagaccctggagaaggtgtgcgtggagacggtggagagtggggccatgaccaaggacctg
gcaggctgcatccacggcctcagcaacgtgaggctgaacgagcacttcctgaacaccacg
gacttcctggacaccatcaagagcaacctggacagagccctgggcaagccgtag
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