Lemur catta (Ring-tailed lemur): 123646130
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Entry
123646130 CDS
T08326
Symbol
GNE
Name
(RefSeq) bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase isoform X1
KO
K12409
bifunctional UDP-N-acetylglucosamine 2-epimerase / N-acetylmannosamine kinase [EC:
3.2.1.183
2.7.1.60
]
Organism
lcat
Lemur catta (Ring-tailed lemur)
Pathway
lcat00520
Amino sugar and nucleotide sugar metabolism
lcat00541
Biosynthesis of various nucleotide sugars
lcat01100
Metabolic pathways
lcat01250
Biosynthesis of nucleotide sugars
Module
lcat_M00955
CMP-Neu5Ac/Neu5Gc biosynthesis, animals, UDP-GlcNAc => CMP-Neu5Ac => CMP-Neu5Gc
Brite
KEGG Orthology (KO) [BR:
lcat00001
]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00520 Amino sugar and nucleotide sugar metabolism
123646130 (GNE)
00541 Biosynthesis of various nucleotide sugars
123646130 (GNE)
Enzymes [BR:
lcat01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.60 N-acylmannosamine kinase
123646130 (GNE)
3. Hydrolases
3.2 Glycosylases
3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
3.2.1.183 UDP-N-acetylglucosamine 2-epimerase (hydrolysing)
123646130 (GNE)
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GFIT
Motif
Pfam:
Epimerase_2
ROK
Hexokinase_1
DRTGG
FGGY_N
Glucokinase
Motif
Other DBs
NCBI-GeneID:
123646130
NCBI-ProteinID:
XP_045418765
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All DBs
Position
10:35884126..35921730
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AA seq
678 aa
AA seq
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MEKNGNNRKLRVCVATCNRADYSKLAPIMFGIKTEPEFFELDVVVLGSHLIDDYGNTYRM
IEQDDFDINTRLHTIVRGEDEAAMVESVGLALVKLPDVLNRLKPDIMIVHGDRFDALALA
TSAALMNIRILHIEGGEVSGTIDDSIRHAITKLAHYHVCCTRSAEQHLISMCEDHDRILL
AGCPSYDKLLSAKNKDYMSIIRMWLGDDVKSKDYIVALQHPVTTDIKHSIKMFELTLDAL
ISFNKRTLVLFPNIDAGSKEMVRVMRKKGIEHHPNFRAVKHVPFDQFIQLVAHAGCMIGN
SSCGVREVGAFGTPVINLGTRQIGRETGENVLHVRDADTQDKILQALHLQFGKQYPCSKI
YGDGNAVPRILKFLKSIDLQEPLQKKFCFPPVKENISQDIDHILETLSALAVDLGGTNLR
VAIVSMKGEIVKKYTQFNPKTYEERINLILQMCVEAAAEAVKLNCRILGVDNDGNCAALA
ERKFGQGKGLENFVTLITGTGIGGGIIHQHELIHGSSFCAAELGHLVVSLDGPDCSCGSH
GCIEAYASGMALQREAKKLHDEDLLLVEGMSVPKDEAVGALHLIQAAKLGNAKAQSILRT
AGTALGLGVVNILHTMNPSLVILSGVLASHYIHIVKDVIRQQALSSVQDVDVVVSDLVDP
ALLGAASMVLDYTTRRIY
NT seq
2037 nt
NT seq
+upstream
nt +downstream
nt
atggagaagaatgggaataaccgaaagcttcgggtttgtgttgctacttgcaaccgcgca
gattattctaaacttgcccctatcatgtttggcattaaaacggaacctgaattctttgaa
cttgatgtggtggttcttggctctcacctgatagatgactatggaaatacgtaccgcatg
attgaacaagacgactttgacattaacaccaggctgcacactattgttagaggagaagat
gaggcagccatggtggagtcagtaggcctggccctagtgaagctaccagatgtccttaat
cgcctgaagcctgatatcatgattgttcatggagacaggtttgatgccctggctctggct
acatctgctgccttaatgaatatccgaatccttcacattgaaggtggggaagtcagtggg
accattgatgactctatcagacatgccataacaaaactggctcactatcacgtgtgctgc
acccgaagtgcagagcaacacctgatatccatgtgtgaggaccatgatcgcatccttttg
gcaggctgcccttcctatgacaaacttctctcagccaagaacaaagactatatgagcatc
attcggatgtggttaggtgatgatgtaaaatctaaagattacattgttgcactgcagcac
cctgtgaccactgacattaagcattccataaaaatgtttgagttaacactggatgcactt
atctcatttaacaagcggaccctagttctatttccaaatattgatgcagggagcaaggag
atggtccgagtgatgcggaagaagggcattgagcatcatcccaattttcgtgcggttaaa
catgtcccatttgaccagtttatacagttggttgcccatgctggttgtatgattgggaac
agcagctgtggggtacgagaggttggagcttttggaacacccgtgatcaacctgggaacc
cgtcagattggaagagaaacaggggagaatgtccttcatgtccgggatgctgacacccaa
gacaaaatattgcaggcgctgcaccttcagtttggtaaacagtacccttgttcaaagata
tatggggatggaaatgctgttccaaggattttgaagtttctcaaatctattgatcttcaa
gagccattgcaaaagaaattctgctttcctcctgtgaaggagaatatctctcaagatatt
gaccatattcttgaaactctaagtgccttggctgttgatctcggcggaacaaatctacga
gttgcaattgtcagcatgaagggtgaaatagttaagaagtatactcagttcaatcctaaa
acctatgaagagaggattaatttaatcctacagatgtgtgtggaagctgccgcagaagct
gtaaaactgaattgcagaattttgggagtagacaatgacggcaactgtgctgccctcgca
gaaaggaaatttggccaaggaaagggactggaaaactttgtaacacttatcacaggcaca
ggaattggtggtgggatcatccatcagcatgaattgatccatggaagctccttctgtgct
gcagaacttggccaccttgttgtgtctctagatgggcctgactgttcctgtggaagccat
gggtgtatcgaagcatatgcctcaggaatggccttgcagagggaagcaaaaaagctgcat
gatgaggacctgctcttggtggaagggatgtcagtgccaaaagacgaagctgtgggtgca
ctccatctcatccaggctgcaaaacttggcaatgccaaggcccagagcatcttaagaaca
gctggaacggctttgggtcttggggttgtgaacatcctccacaccatgaatccttccctt
gtgatcctctctggagtcctggccagtcactatatccacattgtcaaagacgtcatccgc
cagcaggccttgtcctcggtgcaagacgtggacgtggtggtttcggacttggttgacccc
gccctgctaggagctgccagcatggttctggactacacaactcgcaggatctactaa
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