Lemur catta (Ring-tailed lemur): 123646570
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Entry
123646570 CDS
T08326
Symbol
SETX
Name
(RefSeq) probable helicase senataxin isoform X1
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
lcat
Lemur catta (Ring-tailed lemur)
Pathway
lcat05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
lcat00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
123646570 (SETX)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
lcat03021
]
123646570 (SETX)
Enzymes [BR:
lcat01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
123646570 (SETX)
5.6.2.5 RNA 5'-3' helicase
123646570 (SETX)
Transcription machinery [BR:
lcat03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
123646570 (SETX)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AAA_11
AAA_12
AAA_19
AAA_30
UvrD-helicase
AAA_22
nSTAND3
ResIII
Helicase_RecD
AAA_16
UvrD_C_2
Motif
Other DBs
NCBI-GeneID:
123646570
NCBI-ProteinID:
XP_045419649
LinkDB
All DBs
Position
10:4271538..4340817
Genome browser
AA seq
2675 aa
AA seq
DB search
MTTCCWCTPGGGSTVDFLKCYVSKTQSSEFQTADEDLCYCLECVTEYHKARDELPFLHEV
LWELETSRLINHFEKSMKAEIGDDDELYIVDNNGEAQLFDFTGQDFENKLRVPLLEILKY
PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK
VDRDDYYDLQDVLTCLFKVIELGLLESPDIYTSSVLEKGKLILLPSHMYDTTNYKNYWLG
ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMERQSDDDSVDPFWPALHCFMVILDRL
GSKVWGQLIDPIEALQTIINNVSYNREIQHIRNSSVRTKLEPESYSDDMVTCSQIVYNYN
PEKTKKDSGWRSAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIPFVQSLMD
LKDLGVAYIAEVIHHLHSEVKDVLNQTDAVCDKVTEFFLLILVSVIELHRSKKCLHLLWI
SSQQWVEVVVKCAKLPTTAFARSSEKSSGNCSKGTAMISSLSLHSMPSNSVQLACVQLIR
SLLKEGYQLGQQTICKRFWDKLNLFLRGNLSLGWQLTSQETHELQTCLKQIIRNIKSKIP
PCSTLVDLTPACKTPPASCDKEESEQIEKKSIKDMHCLENSSPTFSKELMKGDIYQVPES
ISIKASNTVKEADNEENYRKDLKLEDHRSVESCLKQDNKSLFIEKAQDQIKISTRKQKSV
KENSSVTPQNCTSRNGQGRGSDRKIISTESLEKVSTSNAGLSSKDDALGKTSKPKTKTQK
KDDICTKLSHVIKKQHKKRTLVHNAINLEENLTTSDTESFYSGKATEVQKGDGFIHNLSS
DPDGIPGANKNGEQKSQNSLLLKKKQVKNEELDIFCSHENNYKIQERHPDQDLVSFTEMT
DILVKKMSPFKAPVTVVESREKEMSKSTLVSSNLTIEQAPGISPKSETLTDSQIDRDLHK
LSLMAQASVTKFPSDSTQKSSSQLQRKVKDEKRCFTANQNNVGDTGCGQVIIISDSDDED
EGILGGEKHTKQDKACTEKQCPEQHVSAVTSNVEKKPVKKEQTKSLLQFEDSDSQFFEFE
SPSEVFSVWQDHKLDSSVREDEKNSCLTHMTNTTNIWDDDTDYVSEEVIKKVAEDIEGHT
EAQSSSISVEEFRETEGKKPKRKRFRKKPTVEDPVSPSSSVRSEDQSHILNKRDIPENDL
KKSRDIKTITPNSSIQRATVVSPRKSSPKLCTCPEPVRRVPLSKTKKAHSDTKKGQTKNS
NYIRCRTSPAIVPPKKFRQCPEPTSTAEKLGLKKAPRKAFDLSQRSLESLVQLRDYGKTV
GVVDTGKKTKLIPPQALSVKNNKKLLTSQDLQFQRQIRHKSQQNRQGLFDYGSTDATRAG
PHTAQNSDTFVPESDRSDYNYTGGTKALANSNGKQLIKCMSAEPETVKEKYVSQATDDAC
LLNQCDSVVLNGTPTNEIIVSASEDPLAGGDPIIPPIELATLKEGESESNSDIEEDNLFL
TQNDPEDMDLCSQVENNVKLIEVVHGKDTVQVEVPVSWPQLESLSGTKCKYKDCVETMKN
QSEYCSKHSEAKAADEDVFRKPGLPLSASKPSRPSTTKIFSSKSTSRIANLSKSLENATA
LSPALKNKPNGVQSILKVPQTAPIVSQKPVEEMKSLCNILHPQTPNNSNRQGYKLLFGEN
KSFSTSSPVNILLSSQSISDTFVKEVLKWKYEMFLNFDHCGPPASLCQSISRPVPVRFQD
CGDYFNVFFPLMILNTFETVAQEWLSSPNKENFYQLHLRKFPADYKNCWEFMVYLEECEL
AKQLHPKENDLVFLVTERQNGEKKDIERNCMQDLHEYHCGYVHKFRRTSVMRNGKSECSL
SIQTQDNLPANLNELVKCIVISSLVTTQRKLKAMSLLNGRNQLARAVLNPNPMDFCTKDL
LTTTSERIIAYLKDFNEDQKKAIETAYAMVKQSPSVAKICLIHGPPGTGKSKTIVGLLYR
LLTENQRKGSSDENFNAKIKQNRVLVCAPSNAAVDELMKKIILGFKEKCKDKKNPLGNCG
DINLVRLGPEKSINNEVLKFSLDSQVNHRMKKDLPSHVQDMHRKKDSLDHQLDELSRQRA
LCRGGREIQRQELDEKIAEVSKERQELASKIKEVQGRPQKTQSIIILESHVICCTLSTSG
GLLLESAFRGQGGVPFSCVIVDEAGQSCEVETLTPLIHRCNKLVLVGDPKQLPPTVISMK
AQEYGYDQSMMARFYKLLEDNVEHNMIGRLPIVQLTIQYRMHPDICLFPSNYIYNRSLKT
NRQTETFRCSSDWPFQPYLVFDVGDGSERRDNDSYVNVQEIKLVMEIIKLIKDKRKDVTF
RNIGIITHYKAQKTMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANAMQGSI
GFLASLQRLNVTITRAKYSLFILGHLRTLMENQHWNHLIQDAQKRGAIIKTCDKNYRHDA
MKILKLKPILQRSLTHPPTIAPEVSRPQGGLPSNKLDSGFAKTSFVSPLYHTPPDCSEAA
VTSKDPERSPVQDLLRDPRLLRRMGADANGKFLRDPQSLSPQHSGATPPAGEPSFPVPQQ
DLGSVVQQSAVTAPSTHKPHVQCEPPAASADASNSKRKCSDLEEGLSHRRETRTLSEGEQ
EKHGSVPHHADRNSGWDKKRLEREEDSSFKKRKLS
NT seq
8028 nt
NT seq
+upstream
nt +downstream
nt
atgaccacatgttgttggtgtacaccaggtggtggttccaccgttgacttcttaaagtgc
tatgtgtctaagacccaatccagtgaatttcaaacagctgatgaagacctctgctactgc
ttagagtgtgtgactgagtaccacaaagcaagagatgaattgccattcttgcatgaggtt
ttatgggaattagaaacctcacgtctcataaatcactttgaaaaatccatgaaagcagaa
attggagatgatgatgaattatatatagtggacaacaatggagaggcacaactgtttgac
tttactggccaagactttgaaaataagcttcgagttcctcttcttgaaatactcaaatat
ccttacctgcttctacatgaacgtgttaatgaattatgtgttgaagcactttgtcggatg
gaacaagccaattgctcctttcaggtgtttgacaaacatccagggatctatctgttcttg
gtccatcccaatgaaatggttcgacgctgggctatcctgactgcaagaaacttgggaaaa
gtggacagagatgattattatgacttacaagatgttttaacttgcctttttaaagtcatc
gagttggggcttttagaaagtccagacatttatacttcttctgtccttgagaagggtaaa
ctgattcttctgccctcacacatgtatgatactaccaactacaaaaactattggttaggt
atttgcatgttgctgaccattcttgaggagcaagccatggattctctgttgttgggctca
gacaagcaaaatgattttatgcagtcaatacttcacaccatggagaggcaatcagatgat
gatagtgtggatcctttctggccagcattacattgtttcatggtgattctggatcgcctg
ggatccaaggtctggggtcaacttattgaccccattgaggcattgcaaaccattataaac
aatgtgagctacaatcgagagatccaacacatacggaacagttctgtgaggaccaagtta
gaaccagaatcatattcggatgatatggtgacttgcagccagattgtatacaattataat
cctgaaaagaccaaaaaggattctggatggagatcagccatttgcccagattattgtcct
aacatgtatgaagaaatggaaacgttagccagtgtacttcagtcagatattggtcaagac
atgcgtgttcataacagcacatttttgtggttcataccttttgttcagtccctcatggat
cttaaggatttgggtgtggcttacatagcagaggttattcatcatctgcactccgaagtc
aaagatgtcctcaaccaaacagatgctgtgtgtgacaaagtcactgaattttttcttcta
attttggtatcagtgattgaactgcatagaagtaaaaaatgtttacatttgctatggatt
agttcccaacaatgggtggaagtcgtcgtgaaatgtgccaagcttcctaccacagcattt
gcacggagttctgagaagtcatctggaaattgctccaaaggaacagcaatgatatcatca
ctgtcattgcattcaatgccatctaactctgtacagcttgcttgtgtgcagctgattaga
agtctccttaaagaaggttatcagcttgggcagcagactatttgcaagagattttgggat
aagcttaacttattccttcggggaaatttatctctaggttggcagttgactagtcaggaa
acccatgagttacaaacttgtttaaagcaaattattagaaacataaaatcaaaaatacct
ccatgtagcactttagtggatctgactcctgcatgtaaaacccctcctgcatcttgtgat
aaagaagaaagtgaacaaatagagaagaagtctataaaagacatgcattgtctagaaaac
tccagcccaacattttctaaagaactgatgaaaggtgacatatatcaagtaccagaaagt
atatcgatcaaagcaagtaacactgtaaaagaagcggataatgaggaaaattataggaag
gatttgaaattagaagatcatcggtcagttgagtcatgcttaaagcaggataataaaagc
ctttttattgaaaaagctcaggatcaaattaaaataagtacaaggaagcagaagtctgta
aaagagaactcctcagttaccccacagaattgtacttcaagaaatggtcaaggaagagga
agtgacagaaaaataatatcaactgaatctctggaaaaagtgtccacatcaaatgcaggt
ttatcttccaaggatgatgcccttggtaaaacctcaaaaccaaaaaccaagacacagaag
aaagatgacatctgtacaaagttatcacatgtaataaagaagcaacataagaaaagaact
ttggtccataatgctatcaatttagaggaaaacctgactacatctgacactgagagtttc
tattcagggaaagctacagaagttcagaaaggggatggctttatacacaatctatcttca
gaccctgatggtattccaggtgctaataaaaatggagaacaaaaatctcaaaatagctta
ttactgaaaaagaaacaagtaaaaaatgaagagttagatattttctgttcccatgaaaac
aattataaaatccaggaacgtcatcctgatcaagatttggtctcatttacagaaatgacc
gatattttagtgaagaaaatgtctccctttaaagctccggtgactgtagttgaatcgaga
gagaaggaaatgagtaagagtactctggtttcttctaacttgacaatagagcaggcccct
ggcatcagtcctaagtctgaaaccttaacagattctcagatagacagagatctccacaaa
ttatctttaatggctcaagccagtgttactaagtttccatcagattcaactcaaaaaagc
tcatcccagctccaaagaaaagtgaaagatgaaaaaagatgttttacagctaaccaaaat
aatgttggagacactggctgtggacaggttattattatttcagattctgatgatgaagat
gaaggaattctgggtggtgaaaaacacacgaaacaggacaaagcatgcacggagaaacaa
tgtccagagcagcatgtttcagcagttactagtaatgtggaaaagaagccagtaaagaaa
gaacaaacaaagtctcttctgcagtttgaggattctgattctcagttttttgagtttgaa
agtccatctgaagtgttttcagtttggcaagatcataaactagacagttcggttcgagag
gatgagaaaaattcatgtttgactcacatgactaataccacaaatatttgggatgatgat
acagattatgtatctgaagaggttattaaaaaagtagcagaagacattgaaggacacaca
gaagcacagagtagtagtatttctgttgaggaatttcgtgaaactgaagggaaaaaacct
aagagaaaacgatttagaaaaaaaccaacggttgaagatcctgtaagcccttcatcatct
gtcagaagtgaggaccagtctcatattcttaataagagagacattcctgaaaatgattta
aaaaaaagtagagacataaagactataactcccaactcaagtattcagagagccactgtg
gtttccccaaggaaatcttctccaaagctttgtacttgtccagaacccgttaggagagtc
ccactttctaaaactaagaaagcacattcagataccaaaaaaggacagactaaaaattca
aattacatacgttgtaggacatctcctgcaatagtgccaccaaagaaatttcgccagtgt
cctgagccaacctcaacagctgagaaacttggtctgaaaaaggctcctcgtaaggcattt
gacttgtcccagcgatctttagagtctttagttcaattacgtgattatggcaaaactgtt
ggtgtagttgatactggaaaaaagactaaattaattcctcctcaggctctttctgtcaaa
aataataagaaactcctaaccagtcaagatcttcaatttcaaaggcagataagacacaaa
tcacaacaaaatagacaagggctctttgattatggaagtacggatgctacaagagcaggg
ccacatacagcacagaattctgacacatttgtgccagaatctgataggtcagattataat
tatacaggaggaactaaggcacttgctaacagtaatggaaaacagttaataaaatgcatg
tctgctgaaccagaaaccgtaaaagaaaaatatgtttctcaggcaactgatgatgcttgt
cttttgaaccagtgtgattctgtagtgttaaatggaacaccaacaaatgaaataatagtc
tctgcttcagaggaccctttagctggaggggatccaataatacctcctatagagctggca
actttgaaagagggagaatctgaatccaatagtgacatagaggaagataatttattttta
acacaaaatgatcctgaagatatggatttgtgttcacaagtggagaataatgttaaactc
attgaagtagttcatggaaaagatacagttcaggtagaagttcctgtaagttggcctcag
ttggaatctttgagtggcacaaagtgtaaatacaaagattgtgtcgaaaccatgaaaaac
cagagtgaatactgctcaaagcactctgaagccaaagcagcagatgaagatgtatttcgt
aaacctggcctgcctctttctgcatctaaaccttcaagaccttccactactaagattttt
agctcaaaaagtacttcacgaattgctaatctttccaagtctttggaaaatgctacagca
ctttcaccagctctaaaaaataagccaaatggggtacaatctattttgaaagtaccacag
acagctcccatagtatctcagaagccagtggaggaaatgaagagtttgtgcaatattctt
catcctcagactccaaataattctaacaggcaaggttacaaacttctgtttggtgagaac
aaatctttttcaacttcctctccagtaaacattctgttatcatctcagtctatctctgac
acctttgttaaagaggtcttaaaatggaagtatgaaatgtttttgaactttgatcattgt
gggccgcctgcaagtctttgtcagtccatctcaagacctgtgcctgtcagatttcaagat
tgtggagattattttaatgtctttttccctttgatgatattgaatacttttgaaacagtg
gctcaggaatggctcagctctccaaataaagagaatttctatcagttgcatttacgaaaa
tttcctgctgattataaaaattgctgggagtttatggtttatttggaggaatgtgaactg
gctaaacagctacatccaaaggaaaatgatttggtgtttttggttactgagagacagaat
ggagagaagaaagatatagagagaaattgcatgcaagatctccatgaatatcattgtggt
tatgttcacaagtttcgccgcacttcagtcatgcgtaatgggaagtctgagtgttccctt
tccatccaaactcaggataacttgccagccaatttaaatgagcttgtgaagtgtattgta
atcagttctctggtaactacacaaaggaaattgaaagccatgtctctcttgaatggtcgg
aaccaactggctagagctgttctaaatccaaaccccatggacttctgtacaaaagattta
ctgactacaacgtctgagagaattattgcctacttaaaagatttcaatgaagaccaaaag
aaagcgatagaaaccgcatatgccatggtgaaacagtcaccatcagttgccaaaatatgc
ctaattcatggaccacctggaacaggaaaatcaaaaactattgttggcctcctgtaccgc
ttgctgacagagaaccagaggaaggggtcttcagatgaaaacttcaatgccaaaatcaaa
caaaaccgtgtccttgtgtgcgcaccttccaatgcagctgtggatgaacttatgaaaaaa
attatccttggattcaaagaaaagtgtaaagacaagaagaatcctttgggaaactgtgga
gatataaatttagtgcgactgggtccagaaaagtctattaataatgaggttctaaaattc
agtttggacagccaagttaaccacagaatgaaaaaagacttaccttctcatgttcaggat
atgcatagaaaaaaggattctctagatcatcaactagatgagctttcccgtcagcgagct
ttatgcagaggtgggcgggaaatacagaggcaagaattagatgaaaaaattgccgaagtt
tctaaagaaaggcaggaacttgcttctaaaattaaggaggttcaaggacgcccacagaaa
acacagagtatcatcatcttagagtcccatgtcatctgctgcacattgagcacaagtggt
ggtttactattagagtctgcttttcgtgggcaagggggtgttcccttcagttgtgtcatt
gttgatgaggctgggcagtcgtgtgaagttgagactcttactccactcatccatcgctgc
aacaagcttgttctggtaggagatcctaaacagctccctcccactgtcatttctatgaaa
gcacaggaatatggctacgaccaatcaatgatggctcgcttctacaaactactggaagac
aacgtagaacacaacatgattggcagactacctattgtacagcttactattcagtacagg
atgcatccagacatatgtctcttcccttctaattatatttataacagaagcttgaaaaca
aatagacagacagaaacctttcgatgttcatcagactggccgtttcaaccttaccttgtg
tttgatgtcggagatggttcagaaagacgggataatgactcatatgtaaatgttcaagaa
ataaaactggtgatggaaataattaagcttattaaagacaaaagaaaggatgttactttt
cgaaacattggcataataacccattacaaggcccagaagacaatgattcagaaggatttg
gacaaagagtttgatagaaaaggaccagcggaagtagatactgtggatgctttccagggt
cgtcagaaggattgtgttattgttacctgcgttagagcaaatgccatgcaaggctcaatt
ggattcctggcaagtttgcagaggttgaatgtcaccattacacgagcgaagtacagcctc
ttcatccttggacatttaaggaccctgatggaaaatcagcattggaatcacctgattcag
gacgctcagaagcgtggtgccattattaagacctgtgacaaaaactatagacatgatgca
atgaaaattctgaaactcaagcctatactacagagaagtctgactcacccccctaccata
gccccagaggtgtccagaccacagggtggcttgcccagcaacaagctagacagtggattt
gcaaaaacgtcttttgtttctcctctataccacacacctcctgactgcagtgaagctgct
gttacttcaaaggaccctgaaaggtcacctgttcaggacttacttcgggacccacgactg
ctcaggaggatgggtgctgatgccaatggaaaattcctaagggatccacaatccttgagc
ccccagcattctggagcaacacctcctgcgggggagccaagctttcctgtccctcagcag
gatctgggtagtgttgtgcagcagtccgcggtgactgctccgagcacccacaagcctcac
gtgcagtgtgaacctccagctgccagtgctgatgcttccaatagtaagagaaagtgtagt
gacctggaagaggggctcagtcacaggagagagaccaggactctcagtgaaggagagcag
gagaagcatggctctgtgccccatcatgccgacaggaactctggctgggacaagaagaga
ctagagagggaggaggacagcagtttcaagaaaagaaaactttcatag
DBGET
integrated database retrieval system
