KEGG   Lemur catta (Ring-tailed lemur): 123650624
Entry
123650624         CDS       T08326                                 
Symbol
MAP2K6
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6
  KO
K04433  mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
lcat  Lemur catta (Ring-tailed lemur)
Pathway
lcat04010  MAPK signaling pathway
lcat04015  Rap1 signaling pathway
lcat04218  Cellular senescence
lcat04380  Osteoclast differentiation
lcat04620  Toll-like receptor signaling pathway
lcat04664  Fc epsilon RI signaling pathway
lcat04668  TNF signaling pathway
lcat04750  Inflammatory mediator regulation of TRP channels
lcat04912  GnRH signaling pathway
lcat04935  Growth hormone synthesis, secretion and action
lcat04936  Alcoholic liver disease
lcat05014  Amyotrophic lateral sclerosis
lcat05022  Pathways of neurodegeneration - multiple diseases
lcat05132  Salmonella infection
lcat05135  Yersinia infection
lcat05145  Toxoplasmosis
lcat05161  Hepatitis B
lcat05163  Human cytomegalovirus infection
lcat05167  Kaposi sarcoma-associated herpesvirus infection
lcat05169  Epstein-Barr virus infection
lcat05170  Human immunodeficiency virus 1 infection
lcat05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
lcat05417  Lipid and atherosclerosis
lcat05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:lcat00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    123650624 (MAP2K6)
   04015 Rap1 signaling pathway
    123650624 (MAP2K6)
   04668 TNF signaling pathway
    123650624 (MAP2K6)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    123650624 (MAP2K6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    123650624 (MAP2K6)
   04664 Fc epsilon RI signaling pathway
    123650624 (MAP2K6)
  09152 Endocrine system
   04912 GnRH signaling pathway
    123650624 (MAP2K6)
   04935 Growth hormone synthesis, secretion and action
    123650624 (MAP2K6)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    123650624 (MAP2K6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    123650624 (MAP2K6)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    123650624 (MAP2K6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    123650624 (MAP2K6)
   05161 Hepatitis B
    123650624 (MAP2K6)
   05163 Human cytomegalovirus infection
    123650624 (MAP2K6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    123650624 (MAP2K6)
   05169 Epstein-Barr virus infection
    123650624 (MAP2K6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    123650624 (MAP2K6)
   05135 Yersinia infection
    123650624 (MAP2K6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    123650624 (MAP2K6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    123650624 (MAP2K6)
   05022 Pathways of neurodegeneration - multiple diseases
    123650624 (MAP2K6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    123650624 (MAP2K6)
   05418 Fluid shear stress and atherosclerosis
    123650624 (MAP2K6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    123650624 (MAP2K6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:lcat01001]
    123650624 (MAP2K6)
Enzymes [BR:lcat01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     123650624 (MAP2K6)
Protein kinases [BR:lcat01001]
 Serine/threonine kinases: STE group
  STE7 family
   123650624 (MAP2K6)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_fungal Seadorna_VP7 Haspin_kinase Choline_kinase DUF4344 APH
Other DBs
NCBI-GeneID: 123650624
NCBI-ProteinID: XP_045425484
LinkDB
Position
15:47932687..47977291
AA seq 278 aa
MELGRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFY
GALFREGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVI
HRDVKPSNVLINALGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSV
KSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSAEFVDFTSQCLK
KNSKERPTYPELMQHPFFTLHESKATDVASFVKLILGD
NT seq 837 nt   +upstreamnt  +downstreamnt
atggaactgggacgaggtgcgtacggggtggtggagaagatgcggcacgtacccagcggg
cagatcatggcagtgaagcggattcgggccacagtaaatagccaggagcagaaacggcta
ctgatggatttggatatttccatgaggacagtggattgtccatttaccgtcaccttttat
ggcgcactcttccgggagggtgatgtgtggatctgcatggagctcatggatacatcacta
gacaaattctacaaacaagttattgataaaggccaaacgattccagaggacatcttaggg
aaaatagcagtttctattgtaaaagcattagaacatttacacagtaagctctctgtcatt
catcgagacgtgaagccttccaatgtgctcattaatgctctgggccaagtgaagatgtgc
gattttggaatcagtggctacctggtggactctgttgctaaaacaattgatgcaggttgc
aaaccatacatggccccggaaagaataaacccagagctcaaccagaagggatacagtgtg
aagtctgacatttggagtctgggcatcacaatgattgagttggccatccttcggtttccc
tatgattcgtggggaactccatttcagcagctcaaacaggtggtagaggagccatcgcca
caactcccggcagacaagttctctgcagagtttgttgactttacctcacagtgcttgaag
aagaattccaaagaacggcctacgtatccagagcttatgcaacatccgtttttcacccta
catgaatccaaagcaacagacgtggcatcttttgtaaaactgattcttggagactaa

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