Lemur catta (Ring-tailed lemur): 123650680
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Entry
123650680 CDS
T08326
Symbol
ADCY4
Name
(RefSeq) adenylate cyclase type 4 isoform X1
KO
K08044
adenylate cyclase 4 [EC:
4.6.1.1
]
Organism
lcat
Lemur catta (Ring-tailed lemur)
Pathway
lcat00230
Purine metabolism
lcat01100
Metabolic pathways
lcat01522
Endocrine resistance
lcat04015
Rap1 signaling pathway
lcat04020
Calcium signaling pathway
lcat04022
cGMP-PKG signaling pathway
lcat04024
cAMP signaling pathway
lcat04062
Chemokine signaling pathway
lcat04072
Phospholipase D signaling pathway
lcat04081
Hormone signaling
lcat04082
Neuroactive ligand signaling
lcat04114
Oocyte meiosis
lcat04211
Longevity regulating pathway
lcat04213
Longevity regulating pathway - multiple species
lcat04261
Adrenergic signaling in cardiomyocytes
lcat04270
Vascular smooth muscle contraction
lcat04371
Apelin signaling pathway
lcat04540
Gap junction
lcat04611
Platelet activation
lcat04713
Circadian entrainment
lcat04714
Thermogenesis
lcat04723
Retrograde endocannabinoid signaling
lcat04724
Glutamatergic synapse
lcat04725
Cholinergic synapse
lcat04727
GABAergic synapse
lcat04742
Taste transduction
lcat04750
Inflammatory mediator regulation of TRP channels
lcat04911
Insulin secretion
lcat04912
GnRH signaling pathway
lcat04913
Ovarian steroidogenesis
lcat04914
Progesterone-mediated oocyte maturation
lcat04915
Estrogen signaling pathway
lcat04916
Melanogenesis
lcat04918
Thyroid hormone synthesis
lcat04921
Oxytocin signaling pathway
lcat04923
Regulation of lipolysis in adipocytes
lcat04925
Aldosterone synthesis and secretion
lcat04926
Relaxin signaling pathway
lcat04927
Cortisol synthesis and secretion
lcat04928
Parathyroid hormone synthesis, secretion and action
lcat04934
Cushing syndrome
lcat04935
Growth hormone synthesis, secretion and action
lcat04970
Salivary secretion
lcat04971
Gastric acid secretion
lcat04972
Pancreatic secretion
lcat04976
Bile secretion
lcat05032
Morphine addiction
lcat05163
Human cytomegalovirus infection
lcat05166
Human T-cell leukemia virus 1 infection
lcat05200
Pathways in cancer
lcat05207
Chemical carcinogenesis - receptor activation
lcat05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
lcat00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
123650680 (ADCY4)
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
123650680 (ADCY4)
04072 Phospholipase D signaling pathway
123650680 (ADCY4)
04024 cAMP signaling pathway
123650680 (ADCY4)
04022 cGMP-PKG signaling pathway
123650680 (ADCY4)
09133 Signaling molecules and interaction
04082 Neuroactive ligand signaling
123650680 (ADCY4)
04081 Hormone signaling
123650680 (ADCY4)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
123650680 (ADCY4)
04062 Chemokine signaling pathway
123650680 (ADCY4)
09152 Endocrine system
04911 Insulin secretion
123650680 (ADCY4)
04923 Regulation of lipolysis in adipocytes
123650680 (ADCY4)
04913 Ovarian steroidogenesis
123650680 (ADCY4)
04915 Estrogen signaling pathway
123650680 (ADCY4)
04921 Oxytocin signaling pathway
123650680 (ADCY4)
04926 Relaxin signaling pathway
123650680 (ADCY4)
04935 Growth hormone synthesis, secretion and action
123650680 (ADCY4)
04918 Thyroid hormone synthesis
123650680 (ADCY4)
04928 Parathyroid hormone synthesis, secretion and action
123650680 (ADCY4)
04925 Aldosterone synthesis and secretion
123650680 (ADCY4)
04927 Cortisol synthesis and secretion
123650680 (ADCY4)
09154 Digestive system
04970 Salivary secretion
123650680 (ADCY4)
04971 Gastric acid secretion
123650680 (ADCY4)
04972 Pancreatic secretion
123650680 (ADCY4)
04976 Bile secretion
123650680 (ADCY4)
09156 Nervous system
04724 Glutamatergic synapse
123650680 (ADCY4)
04727 GABAergic synapse
123650680 (ADCY4)
04725 Cholinergic synapse
123650680 (ADCY4)
04723 Retrograde endocannabinoid signaling
123650680 (ADCY4)
09157 Sensory system
04742 Taste transduction
123650680 (ADCY4)
04750 Inflammatory mediator regulation of TRP channels
123650680 (ADCY4)
09149 Aging
04211 Longevity regulating pathway
123650680 (ADCY4)
04213 Longevity regulating pathway - multiple species
123650680 (ADCY4)
09159 Environmental adaptation
04713 Circadian entrainment
123650680 (ADCY4)
04714 Thermogenesis
123650680 (ADCY4)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
123650680 (ADCY4)
05207 Chemical carcinogenesis - receptor activation
123650680 (ADCY4)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
123650680 (ADCY4)
05163 Human cytomegalovirus infection
123650680 (ADCY4)
09165 Substance dependence
05032 Morphine addiction
123650680 (ADCY4)
09166 Cardiovascular disease
05414 Dilated cardiomyopathy
123650680 (ADCY4)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
123650680 (ADCY4)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
123650680 (ADCY4)
Enzymes [BR:
lcat01000
]
4. Lyases
4.6 Phosphorus-oxygen lyases
4.6.1 Phosphorus-oxygen lyases (only sub-subclass identified to date)
4.6.1.1 adenylate cyclase
123650680 (ADCY4)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Guanylate_cyc
Adcy_cons_dom
AC_N
CD52
Motif
Other DBs
NCBI-GeneID:
123650680
NCBI-ProteinID:
XP_045425624
LinkDB
All DBs
Position
1:64869935..64884887
Genome browser
AA seq
1122 aa
AA seq
DB search
MGWKWLGASEKGPVGPPGSQEVTCRPALPSPGDRGGGDHGPPLQPPAAPQRRPFLRDLLQ
PEPAVPAAAAAAGDRSLRAPGAARRHLGHGQGAGRRPQLPDHCTVCTGRLLAAAGPRFPR
AATAALDASPVRPCVGRTARTGPRLPVHRGCGERLGPASRSPLQVSFFLFVIFTVYAMLP
LGMRDAVVAGLASSLSHLLVLGLYLGPQPYFRPALLPQLAANAVLFLCGNVVGAYHKALM
ERALRATFREALSSLHSRRRLDTEKKHQEHLLLSILPAYLAREMKAEIMARLQAGQGSRP
ESTNNFHSLYVKRHQGVSVLYADIVGFTRLASECSPKELVLMLNELFGKFDQIAKEHECM
RIKILGDCYYCVSGLPLSLPDHAINCVRMGLDMCRAIRKLRAATGVDINMRVGVHSGSVL
CGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHITGATLALLAGAYAVEDAGMEHRDPY
LRELGEPTYLVIDPRAEEEDEKGTAGGLLSSLEGPKLRPSLLMTRYLESWGAAKPFAHLS
HVDSPVCTSTPLPEKALASFSPQWSLDRGRSPRGLDDELDTGDAKFFQVIEQLNSQKQWK
QSKDFNPLTLYFREKEMEKEYRLSALPAFKYYAACTFLVFLSNFIIQMLVTNRPPALAIT
YSITFLLFLLLLFVCFSEHLTRCVLKGPKMLHWLPALSGLVATRPGLRVALGTATILLVF
AMAITSLFFLPASSDCPFRTPNVSSMTFNLSWELPGSLPLISIPYSMHCCVLGFLSCSLF
LHMSFELKLLLLLLWLVASCSIFLHSHAWLSDCLIARLSLGPLDSRPGVLKEPKLVGAMS
FFIFFFTLLVLARQNEYYCRLDFLWKKKLRQEREETETMENLTRLLLENVLPAHVAPQFI
GQNRRNEDLYHQSYECVCVLFASVPDFKEFYSESDINHEGLECLRLLNEIIADFDELLSK
PKFSGVEKIKTICSTYMAATGLNATSGQDAQQDGERSCSHLGTMVEFAVALGSKLDIINK
HSFNNFRLRVGLNHGPVVAGVIGAQKPQYDIWGNTVNVASRMESTGVLGKIQVTEETAWA
LQSLGYTCYRRGVIKVKGKGQLCTYFLNTDLTRTGPPSATLG
NT seq
3369 nt
NT seq
+upstream
nt +downstream
nt
atggggtggaagtggcttggagcaagtgagaaaggcccagtggggcctcctgggtcgcag
gaggtaacctgtcgcccggccctccccagccctggggatcggggcgggggagaccatggc
ccgcctcttcagcccccggccgccccccagcgaagaccttttctacgagacctactacag
cctgagccagcagtacccgctgctgctgctgctgctggtgatcgttctctgcgcgctcct
ggcgctgctcgccgtcacctgggccacgggcagggagctggccgcagaccccagcttcct
gaccactgtactgtgtgcactgggcggcttcttgctgctgctgggcctcgcttcccgcga
gcagcgactgcagcgctggacgcgtcccctgtccgcccttgtgtgggccgcactgctcgc
actgggccacggcttcctgttcaccgggggtgtggtgagcgcctgggaccagcttcccgc
tccccgctccaggtgtccttttttctcttcgtcatcttcaccgtgtatgccatgctgccc
ttgggcatgcgggacgctgtggtcgcgggcctcgcctcctcgctctcgcacctgctggtc
ctcgggctgtacctcgggccccagccgtacttccggcctgcgctgctaccgcagctggca
gcaaacgcggtgctgttcctgtgcgggaacgtggtgggagcgtaccacaaggcgttgatg
gagcgcgcgctgcgcgccacgttccgggaggcgcttagctccctgcactcacgccggcgc
ctggacactgagaagaagcaccaggaacacctactcctgtccatccttcctgcttacctg
gcccgagagatgaaggcagagatcatggcacggctgcaggctggacaggggtcacggccg
gagagcaccaacaatttccacagcctctacgtcaagaggcaccagggagtcagtgtgttg
tatgctgacatcgttggcttcacgcggctggccagtgagtgctcccctaaggaactggtg
ctcatgctcaacgagctctttggcaagtttgaccagatcgccaaggagcatgaatgcatg
cggatcaagatcctgggggactgttactactgtgtctccgggctgccgctctcgctgcca
gatcacgccatcaactgcgtgcgcatggggctggacatgtgccgagccatcaggaaactg
cgggcagccactggtgtggacatcaacatgcgtgtgggcgtgcactccggcagtgtgctc
tgcggagtcattgggctgcagaagtggcaatatgatgtatggtcccatgacgtcacactg
gccaatcacatggaggcaggcggcgtaccaggacgagtgcacatcacaggggccacactg
gccctgctggcaggggcttatgccgtggaggatgcaggcatggaacaccgggacccatac
cttcgggaactaggggagccaacatacctggtcatcgatccccgggccgaagaggaggat
gagaagggcactgcaggagggttgctgtcctctctggagggccccaagctgcgcccatca
ctattgatgactcgctacctggagtcctggggtgccgccaagccttttgcccacctgagc
cacgtagacagccctgtgtgcacctccacccctctcccggagaaggccctggcttccttc
agcccccagtggagcctggaccggggccgcagcccccggggactggacgatgagctggac
accggggatgccaagttcttccaggtcatcgaacagctcaactctcagaaacagtggaag
cagtcgaaggacttcaacccgctgacactgtacttcagagagaaggagatggagaaagag
tatcgactgtctgcacttcctgccttcaaatactatgcagcctgcaccttcctggttttt
ctctccaacttcatcatccagatgctggtgacaaacaggcccccggctctggccatcacc
tatagcatcaccttcctcctcttcctcctcctcctcttcgtctgcttctcagagcacctg
acgaggtgtgtcctgaaaggccccaagatgctgcactggctgcctgcactctctggcctg
gtggccacacgaccgggattgcgagtagccctgggcactgccaccatcctcctcgtcttt
gccatggccattaccagcctgttcttcctcccagcatcatcggactgccctttccggact
cccaatgtgtcctccatgactttcaacctctcctgggagctcccggggtccctgcctctc
atcagcatcccatactccatgcactgctgcgtgctgggcttcctctcctgctccctcttc
ctgcacatgagcttcgaactgaagctgctgctgctcctgctctggctggtggcctcctgc
tccatcttcctgcactcccacgcctggctgtccgactgcctcatcgcccgcctctctctg
ggccccttggactccaggccgggagtgctgaaggagcccaaactggtgggagctatgtcc
ttcttcatcttcttcttcaccctccttgtcctggctcggcagaatgagtattactgccgc
ctggacttcctgtggaagaagaagctgaggcaggagcgggaggagacagagacaatggag
aacctgactcggctgctcttggagaatgtgctccctgcacacgtggccccccaattcatt
ggccagaaccggcgcaacgaggacctctaccaccagtcctacgagtgtgtctgtgtcctc
ttcgcctcagtcccggacttcaaggagttttactctgaatccgacatcaaccatgagggg
ctagagtgtttgcggctgctcaatgagataattgctgattttgatgagctgctctccaag
cccaaattcagcggagtggagaagatcaaaaccatctgcagcacctacatggcagccaca
ggcttaaatgccacctcgggacaggatgcacaacaggatggtgagcgaagctgtagccac
cttggcaccatggtggaatttgctgtggccctgggctctaagctggacatcatcaacaag
cactcattcaacaacttccgcctgcgtgtggggttgaaccatggaccagtagtggccgga
gtgattggggcccagaagccacaatatgatatttggggcaacacagtgaacgtggccagc
cgcatggagagtacaggagtccttggcaagatccaagtaactgaggagacagcctgggcc
ctgcagtccctgggctacacctgctacaggcggggtgtcatcaaggtcaaaggcaaaggg
cagctctgcacctacttcctgaacacagacttgacacgaactggacctccctcagccacc
ctaggctga
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