Lates calcarifer (barramundi perch): 108881149 Help Entry 108881149         CDS       T04895                                  Name (RefSeq) LOW QUALITY PROTEIN: obscurin   KO K17531   obscurin-RhoGEF [EC:2.7.11.1] Organism lcf  Lates calcarifer (barramundi perch) Pathway lcf04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:lcf00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     108881149  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:lcf01001]     108881149   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:lcf04131]     108881149 Enzymes [BR:lcf01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      108881149 Protein kinases [BR:lcf01001]  Serine/threonine kinases: CAMK group   Trio family [OT]    108881149 Membrane trafficking [BR:lcf04131]  Others   Rho GTPase associated proteins    Rho guanine nucleotide exchange factors (GEFs)     108881149 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  I-set Ig_3 ig Ig_2 V-set Pkinase Ig_5 PK_Tyr_Ser-Thr Ig_4 Izumo-Ig SOS1_NGEF_PH RhoGEF C2-set_2 fn3 ABC1 Kdo IQ_SEC7_PH IQ Kinase-like RIO1 PH APH Lep_receptor_Ig RHG20_PH Motif Other DBs NCBI-GeneID:  108881149 NCBI-ProteinID:  XP_050933200 UniProt:  A0AAJ8BHL7 LinkDB All DBs Position LG17:complement(13798530..13834478) Genome browser AA seq 6203 aa AA seqDB search MSKTHTLFFKSVRPEHAGEIRFTAQRVSSYATLTVKELPVQIVRPLRVKIAMYRHRGLLE CQVSRPNAQVRWYKNGKELLPGKKYQLISQDVYRQLTIDDVSSSDEDTYTCDAGDDETSC QLLVEEQAISIVRGMSSVEVMEPEPALFQVETSLKSGRPPRWTLNGKVLEPCAMVNIDRE GTLHSLCLTSTESSMSGPVVFVAGKSRSTAQLTVKERPLQVVRHMDDVEAKENSSVTLSC QFTPSPRVVRWFKGRTALKTSNKYSMKREGKRAALTIHGLTGMDGGQYRCMAGGSQSSAH VKVEVRTLKLVKYLEAVEIEEDGVASFSCELNYVVANVEWLLNNVRLYSNAISRIQHMGT MHSLTLKKLRPQESRITFKAGLLSDTTTLKVKERPAVFLRSLEDAVGEEQGEVCLQCEIS KETVTPVWRKDGMVLTADDKYEILQFGKSMALVIHSLSKDDTGQYTCDLGTSQTKAKVTV HDLHITIVQRMKTTSVLEGESCTFECLLSHSLDDEPSWTINGQAVVTNSRIQVINNGHKY QMTIRDAVLTDAGDVVFAIKDLSCRTMLFVKEKPVHIFRDLLNVKAVPGEDAELSCEITK PEVTIRWLKDGHLIRQSPKYEMSVEKNLAWLVIKNTTIRDSGEYCCEAEGIASRAKLEIR ELQHTFARELRDTRAEEKAKVTLECETRRPAKRVTWLKGMMELRSGRKYVIRQKGVVLSL TITSLEKLDTDVYTCDVGTMQTRAELTIQGQKVLILDELEDVECLEGDTVTFRCRICPSD YIGVKWYLDETLLYTNELNEIQMLPGGYHTLTFKQLARKDTGTISFAAGDKRSYASLLVR ERRPTIIKALEDCEAIEGGGLVLSCVASKPCHILWYKDGCLMWHSSRYFASRSGCEARLT IREVCNSDAGVYECSAGSVTTRAVVTVKAVPAEFTQPLKTVEAKEGETVTLTCEYSLPGV QFHWRKGYESIRSGDKYVMKQRKTINSLTIKALRPEDSGEYTCQCRDHHTTASLKVHAVP ISFVQQLKNMQVEEGSNVLLRCELSKPGIPVEWRKGNELLRNGVKHQIRKRETTLELLIW KPVPEDSGVYSCVCAEQTTSATVKITALPVTFKQKLRNVLIEEGNTATLRCELSKPGHTV EWRRRGNELIRNGEKYHIRQRDMLIELRIVDVTPEDSDIYTCICGNIETTATLTVNALPI TFKQKLRNLQVEEGHNITLYCEISKPGIPVEWRLGGDSLENGEKYQIKQRDSALELTIRD AVLEDSGVYTCVCREQRTKATVKVIAVPATFKVSLKSQEAEEGSSVTLRCELTKKGVPLQ WQREGQVISEEMPRGKYQMKVEGRAALMTILSVQPEDAGKYSCIAGDEKTTAEIKVKPLP VTFKREIQRLVAKEGHSGVFSCELSKPGAPVEWKKGRVILKPGEKYKMKQEGRLTKLVIN NIEESDAGKYTCKTKDNQSTAELTVQGLPPSFKLPLVNQEVTEGNSVVLRCELNKPAPSV EWRRRGELLKNGDKYQMRKKDLQVEMKIMDLGLDDTGDYTCVCGEQRTTAMITVNERPIK FLQELKNIQVQEGNGVTLCCELSKPGVPVQWKKGDNVLNSGEKYHMRQNDSTLELVIRKS QPEDSGTYSCVCEDVKTTATIIITAIPVTFKQKLKNQEAVEEGSVTLRCELSKPGVPVEW RRDAQLLKEGEKYQMKQEGRMAEMLIRNLTLTDAGEYCCFVGTVVTSADIKVRALPVTFK QEVENLEVKEGDSGVFCCELSKPGAPVDWRKGRVVLKPGYKYEMKQEGHLTKLIINNVEE SDAGKYTCKTKDCQSTAELTVKAPPVTFKMKLRNLQVEEENSVTLSCELSKPVLAVEWRK GEELLKNNFKYQIKNRNSVMELTIKNAQLEDSGLYSCTYGDAKTTANVTITPIPLTFKMG LKNQEAPEGGNVSLRCELSRAGVPVQWWKAEDQLYHGGRYQMTLKGKIAEMQIRNVQPED VGEYSCVFGEQRTTAEVNVRAAASVFFEKELENQAVMEGKSVLLSCEVSSANVPVTWKKD NVVLEEGGRCLLKKKGPTHSLEIKKLLLEDAGEYSCITRGKKTTAKLIVRERVRIVTQLQ DVTVTAGEDAVFVCELSHADVSEGVWWLGSSPLQKNEMNQMTCQGRRHRLVLTMTTPEET GTVAFVIGEERTSARLLVVPKPKVLFEEKPKDVVIMEGETATLSCTISDFTSAVTWRRNH IPLCNGDKYELRKEGKVNLLLIYDVEPMDTGIYSCDTGDVQTSAKLTVTELPPFFQEELQ SVEVEEGGSASLYCELSKLGVPIQWKKSTLLLRASRKYEMKQDGCLLQLHIKDLKPEDSG SYTCQAGSAETTASVTVKELPPFFKKELRSVDAEEEGTASLSCELSKPGVAVQWKRNRLP LRANRKYEMKQDGCLLQLHIKELKPEDSGSYTCQAGSAETSATVTVKEHPPFFKKELQNV KAEEEGSASLCCEVSKPGLSIQWKKNKLPLRPSRKYEMKQDGCILQLHIKELKPEDSGSY TCQAGSAETSATVTVKELPPFFKKDLVSVEAEEEGIASLCCELSKPGVLVQWKKNKLPLR ANRKYEMKQDGCLLQLHIKELKPEDSGSYTCQAGSAETSATVTVKELTPFFNKELQSVEG EEGGTASLYCEASKPGLLVQWKKNKMPLRANRKYEMKQDGCLLQLHIKELKPEDSGSYTC QAGSAETSATVSVKELPAFFKKDLVSVDAEEEGTASLCCELSKPGVSVQWKKNKLPLRAN RKYEMKQDGCLLQLHIKELKPEDSGSYTCQAGSTETSATVTVKEHPPFFKKELQNVKAEE EGSASLCCEVSKPGLSIQWKKNKLPLRPSRKYEMKQDGCILQLHIKELKPEDSGSYTCQA GSAETSATVTVKELAPFFNKELQNVEGEDGETASLYCEVSRPGVSVQWKKNRLPLRASRK YEIKQDGCLLQLHIKDLKPEDSGSYTCQAGSAETTATVTVKELVPFFNKELQSIQTEEGG TVSLSCEVSKPRLSVQWKKNGLPLRANRKYEMKQDGCLLQLHIKELKPEDSGSYTCQAGS AETSATVTVKELAPFFHKNLQNVEAEEGGTASLYCELSKPGLLVQWTKNKLPLRANRKYE MKQDGCLLQLHIKELKPEDSGSYTCQAGSAETSANVSVKELPPFFKKNLQSIDAEEGGTV SLSCEVSKPGLSVQWKKNKLPLRATKKYEMKQDGCLLQLHIKELKPEDSGSYTCQAGSAE TIATVSVKELQPTPPKAEPPTLLPRSKGAASKTTSTPENEKPGLPEAKPVPPEPKKRINR KALPITNSEKDVEPVLDLKQCVVKENNEAQKGIQPVKPVEKDLNVVQNITQLERNKEKDS EEHEKADKSVRLLEKDGRIDMKVEEPGRSLEIDNEVFLEKRQQEMNLEESIEAGLKVNQS ERILGDAVAKQKKQILICPEMENEVEQSLEQPGKPFEKTSEVEKKVKHPGTQTSEDEKGH LKPQEKLIAKETTREQDVKSTVKQSAEDKDYVQQQVPTEAEREKKPFKQVSSVNLRDKQS VEQQEKPSEREADFVPPKPPMRMRSKAKGGMEKQLSRDTETDQEGQELTEVVVKTTDDQP VKELISPVEKEAKEKPIFERKQSITTDSEIDGKIKPVKTAEKDTNTKQLIKQPVKPMRKE PEVDQEIKLAVEPMRREEHKQTVKMAEDVPLLYISEDETFSEALIEIPADHSKVLPVSSY TDRQTQPSSPPPINVLQKRQPSKDVPPETDISIEDEPQMQEAAVKIQAAFKGYKTRKEMR PVFKEVFKNQSADLHGTVTLVCIVEGKPSTVRWLKNGHQVVSDHRCRIETTEHGVCTLVI KNLTTSDGGIYTCEVVNKFGVTSYNGNITVVQPQQPAHTAQKPVHPPLAAITPLQLAPTK PEVQAKTPTQNLPQTQAQIPTSAADTANYVESVTISLWEAYNLTEQDTPMSPQERRGSSL IAASSMSSPSDYDTAPDIMEPVETGPIVPREVPKPEDQVSPKDEKEETAAPHPPKKLLKV KGAHEGRMRTPSPKHHRAHTPLASTVSGSESEGEEDRQETFEMYVARADCSPNSGNKESF ILKEGQFVEVLDSVHPDRWLVRTKPTKTNPARQGWVCPAYLEKKRKDTFPQMRAPQEDLD GIGSTGEEYRRALSQLVQGLIDGEEEFVKEMKMFTSHQLSYLDSSRQIPINILNQKEIIF RNIKDIVSLHERSILPGLKGCATDDDVAMHLVKHTEDFERYLHYMVGQAQAEACITDKAM QQYFKELTESGKPDAPVMDVLTFLQRPVERIQTYQALLKELIKNKARSGQSCCLLEDAFS MVSCLPWRSDNLHQVSLIENYPAPLTALGEPVRQGVFTVWEESPEIKTASRGHQRQVFLF KECIVLCKLKRDTRMNSDTYTFKNKMKLNDVEIKESVGGDEKSWGLWHEHRGSVRRYTLQ GRSTLAKLPWLKDLKELQQRSSLPTNSPPVFESLLSDCTTKIGQTIKLTCKVTGSPKPVV TWLKDGLPLEDDPRHIITADRFGTCSLILDSLTAEDSGQYTCYATSSMGTAGTLAKVVVQ APPRFVSRLESACLIEGEDIQFTCSTLSTPLPRVRWLKDGRELTDKQKYLILNDARSGIL CLTVISATEADIGQYECELWNELGCVKCKAGLCPAYVPPTDIENDQPQDLPPKDADSEGW STAFVKKWLQTDFSPTSIAKMLFPPGYPEQAQCNTEETVLAATSMDNVAQQPLRYLEEEE EEIYTSEAMQEITDAPPSVQVSTEDLCVEPGQTATFTAIITGRPTPTIQWYKDEDELAAN ENVQIVQHGARCSLTIGCCEGEDSSIYTCFAYNDSGHASCQAQLTVEEGPLECQEREVEL GKRRKLFSVYDVHEEIGRGTFGVVKRVVHRRTGEVFAAKFLPLRSSTRTRAFQERDLLSR LAHPRVACLLDFFCTRRTLVLITEICCSHGLLDHLLLRGSVSEKEVQSYIQQILEGVGHI HSMNILHLDIKPDNILMVYPPKDEIKICDFGFCQEIDISRHQYSMFGTPEFIAPEIVHQE PVSVATDIWAVGVIAYLCLVGRCPFVGETDRTTLLRVGEGTLNWDAPDVTYRSPEAQNFL HLVLQPDPEKRPSAFECLSHEWFQDEHAGEDTDEINTRSLKVFISKTKWQRSLTCIGSVL TLRPVPELLDAPLRDTAVTVPRELQEHSSTSLSSGSSSEYDEADSWDFFQHYSPTEEEEE TEEDYDPLMERAQIPEPFAKLHLDEEEEEEMTLGEEEDGEMVGRRSVLERSMSRQSVASS DVSCQQTPQRERRFSKDSSPSLHLSDWDEGSGSDGGRIPRGSVIRSTFYSTSHQLSPMSA RHMTLRDKFQAKKQERGRKPLRRSVSGRLNEPLIEYVEDETETNRGQRRGSVQPTMQKSC SFDSGVGLTHSNIPPHRRSRSLDEYSRRSPSSPKRTKPGEEEGSQSLKEDFTDDEVAGRN LLAIPSPRRPTRRRGSVAPINGTGTSVPSSLLAGDRRHQAGSGADRGRYLCRLPGSLAES SILEHGGSESSSRLGSYEELSHGHLRGRYRSGESEGYDDQGEPLISSSPSSFQEVKPRDS FPQAPPRNRTRSNPNLSSNSRGQLGPSLTPSPSPSLSSLQAPERPPRSRDKKEGHGLQRH ASAPALEVRPPTGKSPKLGLLKIFRRQSWTGHSYSQLENAELGPTLGEIMKPDTPTMSLR KKMRASASSLTKLFSRSSSKEDVSKGGPIVKGAAPVPPDREHGSGLESPKKRTSKILPSF KIPAFKKTKDLPVRPNKAEVLHLDGGGVLLVWRPVQSNDPITYCVQYCTDGGEWTVLSEE VTDSCYVVKDLPRGASYVFRVGCITKKGAGPFSDASAPVVMATHPEETHVSLIQTETLGS KVTGSEGQTTQKNYNFLSEINRGRFSVVTLCRDVETSQVFAAKITPYQAEQRQLVLREYQ LLRRLHHPHLVQLHNAYLTTHYLVLVEELCPGKELLYSLAARDLYAETHVAELLVQILSA VDYLHSRRIIHLDLKSDNMLVDDGNHVKIVDFGSAQSFTPGQPLTIEHIHGLSESKECRT KVYIVLPKAPEILEGQGVGPETDVWAIGVLSFIMLSADSPFHAEHSWEQDRNIKKGKIQF GRCYPGLSEGALTFMKSSLNNKSWGRPTAAECLQNPWLRAHRVPHKTRPSKVCFSTDKLK AYLQQKEEKRDLVHIKLQGPFFQ NT seq 18612 nt NT seq  +upstreamnt  +downstreamnt atgagtaaaactcacaccctgttcttcaagtcagtcaggccagagcatgctggagagatc aggttcaccgcacagcgtgtgtcatcctatgcaactctcacagtgaaagagctcccagtc cagatagtgcgtcctctgagggtcaagatagccatgtatcgccaccggggtctgctggag tgccaggtgtcacgacccaacgcccaggtcaggtggtacaagaacgggaaggagcttctg cccggtaagaagtatcaactaatcagccaagatgtctacaggcagctgactatcgacgac gtaagctcctcagatgaggacacctacacatgtgacgcaggagatgatgaaacctcatgt cagctcctagtggaggagcaggctatcagtatagtgcgggggatgagctcagtggaggtg atggagccagagccagcactgttccaggtggagaccagcctgaagtcagggaggcctccg aggtggacgctgaacggcaaagtgctggagccatgtgcgatggtgaacatcgacagggag ggcaccctccacagtctctgtctcacctccacagaaagctccatgtccggccctgtggtc tttgtagctggcaagagtcgctccactgctcagcttactgtgaaagaacgaccgcttcag gttgttcgccacatggacgatgtggaggcgaaggagaacagctctgtgactctgagctgt cagttcaccccatctcccagggtggtgcggtggtttaaaggtcgcaccgctctgaagacc tcaaacaagtacagcatgaagagagaggggaaacgagcagcgctgaccattcacggcttg acagggatggatggagggcagtaccgctgcatggctggaggctcccagagctcagcacac gtgaaagtagaagtgcgaacacttaagttggtcaaataccttgaggcggtggaaatcgag gaggatggcgtcgcctcgttctcgtgcgagctcaactatgtggtcgccaacgtggagtgg ctcctcaacaatgtccgcctctattccaacgccatcagcaggatccagcacatgggcaca atgcacagcctcacactcaagaagctgcggccgcaggagagcaggatcaccttcaaagca ggccttctctctgacacaacaaccttaaaggtcaaagagcgtccagcagtgttcctaagg tctctggaggatgcagtaggagaagagcaaggggaggtctgcttgcagtgtgaaatttcc aaagagacggtgactcctgtttggagaaaggatggtatggtcctgacagctgatgataaa tatgaaatactccagtttgggaagtccatggctctggtcatccattcactgagcaaggat gacactggacagtacacctgtgacctgggcaccagccagaccaaggctaaagttacagta catgacttacacatcaccattgttcagcgtatgaagacaacctctgtcctagagggtgaa agctgcacttttgagtgtctcctctctcacagtctcgatgatgagccttcctggacgatc aacggccaggcggtggtcaccaatagtcgtatccaggttatcaacaatggccacaagtat cagatgaccattagagatgctgtactcacagacgctggagacgtggtttttgcaattaaa gatctcagctgtagaaccatgctttttgttaaagagaaaccggtgcacatcttcagggac ctgctgaatgtcaaggcggtgccgggcgaggacgcagagctgagctgtgaaatcaccaaa cctgaggttaccatccgttggctgaaagatggccaccttatccgccagagtccaaagtat gagatgagtgtggagaagaacttggcatggctggtgatcaagaataccaccatcagagac tctggggagtactgctgtgaggccgaaggcattgcctctcgtgccaagctggagatcaga gaactccagcacacatttgcaagggagttgagggacacacgagcagaggaaaaggctaaa gtgaccctggagtgcgagaccaggcggcccgccaagcgtgtgacctggctgaaggggatg atggagctgaggtctggtaggaagtacgtcatcaggcagaaaggtgtggtgctgtccctg accatcacttccctggagaaattggacacggatgtttacacgtgtgatgtcgggaccatg cagacccgggcagagctgaccatacagggccagaaggtgttgatcctggacgaactagag gacgttgagtgtctagaaggtgacacagtcacattcagatgtcgaatctgccccagcgac tacatcggggtcaaatggtacctggatgagactctgctgtacaccaatgagctcaatgag atccagatgttgcctggaggttaccacaccctcacatttaaacagcttgcccgcaaagac actggcactatttcatttgcagcaggggacaaaaggtcgtacgcctcgctgctggtcaga gagagacgtcccaccatcattaaggcgctggaggactgtgaggctattgaaggaggtggt ttggttttgtcctgtgtggcatccaagccatgtcacatcctgtggtacaaagatggctgc ctgatgtggcactcctcaagatattttgccagtcgctccggctgtgaagcacgactgaca atccgtgaggtctgcaacagtgatgctggggtgtacgagtgcagtgctggatctgttaca actagagcagttgtaactgtcaaagccgtcccagcagagttcactcagcctctgaaaaca gtggaggccaaagagggagagactgtgaccctgacctgtgagtactctttgcctggggtc cagttccactggaggaaaggctacgagagtatcaggtctggagacaagtatgtgatgaaa caaaggaagacaatcaactctctaaccatcaaagccctgaggcctgaggactcaggagaa tatacctgccagtgccgagatcaccacacaacagcaagcctcaaagtgcatgctgttcct atttcattcgtacaacaactgaagaacatgcaggtggaggagggtagtaatgttttattg cgctgtgagctgtccaaacctggaataccagtagaatggaggaaaggaaatgagttgtta aggaatggggtcaagcaccagataaggaagagggagaccacattggagctcctgatatgg aagcctgtgcctgaggacagcggggtgtacagctgtgtgtgtgctgagcagacgacatct gccactgtcaaaatcactgctctcccggtcaccttcaagcagaagctgaggaatgtgttg attgaggagggtaacactgcaactttacgctgtgagctgtctaaacctggtcacaccgtg gagtggaggaggagggggaatgaactcatcaggaatggagagaaatatcacattcgacag agagacatgctgattgaactgaggatcgttgatgtgacacctgaggacagcgatatctac acctgcatctgtggaaacatagaaaccactgcaactctgactgtaaatgctcttcccatc accttcaagcaaaagctgaggaacctccaagttgaagaaggacacaacatcacattgtat tgtgagatctctaaacctggcatcccagtggagtggaggctcggaggagactcgttggag aatggagagaagtaccagatcaagcagagggactctgccctggagttgaccattagagat gctgtactagaagacagtggcgtctacacgtgtgtgtgtagagagcagaggacaaaagcc actgttaaggttatcgcggttcctgccacatttaaagtgagtctgaagagccaggaggct gaagaagggagcagtgtgacgttacgctgtgagctgacaaagaagggagtcccgctgcag tggcagagagaaggtcaggtgatctctgaggagatgccacgaggaaagtatcagatgaaa gtagagggaagggcagctctaatgactattctcagtgtccaaccagaagatgcagggaag tacagctgcatcgcaggagatgagaaaaccacggctgaaatcaaagtgaaaccacttcct gtgacattcaaacgagagatccagcgcctggtggcaaaggaaggtcacagtggagttttc tcctgtgagctctccaaacccggagctccggttgagtggaagaaaggcagagttatcctg aagcccggggagaaatacaagatgaagcaggagggacgtctcactaaactggttatcaac aacatagaagagagtgacgctgggaaatacacatgcaagactaaagacaaccaatcaact gcagagctcactgtccaaggtttaccaccgagtttcaagctgccactggtcaaccaggaa gtgacggagggcaacagtgtggttctgcgctgtgagctcaacaaacctgctccgtcggtg gagtggaggagaagaggcgagctgctgaagaatggagacaagtatcagatgaggaagaag gaccttcaggtggagatgaagatcatggacctcggtctggatgacaccggagattatacc tgtgtatgtggagaacagaggacaacagctatgatcacggtgaatgaacggcccatcaaa ttcctccaagagctgaaaaatattcaggtgcaggagggcaacggggtgacgctctgctgt gagctctccaaacctggcgttcccgtgcagtggaagaaaggagacaatgtgctgaacagc ggagagaaataccatatgaggcagaatgactcaacactggaactcgtcattaggaaaagc cagcctgaggacagtggcacatacagctgtgtttgtgaagatgtgaaaaccactgccacc atcatcatcactgcgatcccagtgactttcaagcagaagttgaagaaccaggaagctgtg gaggagggcagtgtgacgctgcgctgtgagctctctaaaccaggagtcccagtggagtgg aggagagacgctcaacttctgaaggagggagaaaaataccagatgaagcaagagggcagg atggctgagatgctgattagaaatttaactctcacagacgctggggagtactgctgtttt gttggcactgttgtgacttcagctgacatcaaagtgagagcccttcctgtgacatttaag caagaggttgagaatttggaagtgaaggaaggggacagtggagttttctgctgtgagctc tccaaacccggagcgccggtggactggaggaaaggcagggttgtcctcaaacctggatac aaatacgagatgaaacaggagggacatctcacaaaactgatcatcaacaatgtggaggag agtgatgctgggaaatacacctgcaaaaccaaagactgccagtcgactgcggagctcacc gtcaaggctcctcctgtcacattcaaaatgaagttaaggaatctgcaggtggaggaggag aacagtgtgacactgagctgtgagttatctaagcctgtcctcgctgtggagtggaggaaa ggagaagagcttctgaagaacaacttcaagtaccagattaagaatcgaaacagcgtcatg gagctgaccatcaaaaacgcacaactagaggacagtgggctctatagctgtacctatggt gatgcaaagaccacagccaatgtcaccatcacacctattcccctcaccttcaaaatgggt ctgaagaaccaggaggcccctgagggaggcaacgtgtcccttcgctgcgaactgtccagg gccggggtgcctgtgcagtggtggaaagcagaggaccagctctatcacggagggaggtat cagatgacgctgaaggggaagatagcggagatgcagatcagaaacgtccagccagaggac gtcggggagtacagctgtgtctttggagagcagaggacgacggctgaagtgaacgtgaga gcggcagcatcggtgttctttgagaaggaactggagaaccaagcagtaatggaggggaaa tctgtgctgctgtcctgcgaagtgtccagtgctaatgtccccgtcacttggaagaaggac aacgttgtgttggaagaaggaggacgatgccttttaaagaaaaaaggccccacccactct ttggagatcaagaaattgcttctggaggatgctggagagtacagctgcatcaccagaggc aagaagaccactgccaagctgatcgtgagggagcgtgtgcggatcgttacacagcttcag gatgtgacagtgacagcgggagaggacgcagtgtttgtgtgcgagctgagccatgcagac gtgagtgaaggtgtgtggtggctcggttccagccctctgcagaagaacgagatgaaccag atgacgtgccagggtcgccggcaccgactggtcctcaccatgacgacacccgaggagacg ggtaccgtggcatttgtgatcggagaggagaggacctctgcacgtctgctagtggtaccc aagcccaaagttttgtttgaggagaagccgaaagacgttgtgattatggaaggagagaca gccactttgtcctgcacaatctctgactttacctcagcggttacctggagacgcaaccac attcctctttgcaatggtgataaatatgagctgcgcaaggagggaaaagtcaacctgctg cttatctacgatgtggagcccatggatactggcatatactcctgtgatacaggagatgtg caaaccagtgccaaactaaccgtaacagagctccctccattctttcaggaagaattgcag agcgtggaagttgaggagggaggttcagcctctctgtactgtgagctgtctaagctcgga gtgccgattcagtggaagaagagcacactgctgctaagagccagcagaaagtatgagatg aaacaagatggctgcctcctccagctccacatcaaggatctcaaacctgaggacagtggc agctacacatgccaagcaggcagcgcagagaccactgcgtctgtgacagtgaaagagctc cctccattcttcaagaaagaattaagaagtgtggatgctgaggaagaaggtacagcctcc ctgtcctgtgagctgtctaaacctggagtagcagtgcaatggaagaggaacagactacct ctgagagcaaacaggaagtacgagatgaaacaagatggctgccttctccagctccacatc aaggagctcaaacctgaggacagtggcagctacacatgtcaagcaggaagtgcagagacc agtgcaactgtgacagtaaaagagcacccaccatttttcaagaaggaattgcagaatgtg aaggctgaggaagaaggttcagcctctctgtgctgtgaggtgtccaaacctgggctgtca atacaatggaagaagaacaagctgccattaagaccaagcaggaagtatgagatgaaacaa gatggctgcatcctccagctccacatcaaggagctcaaacctgaggacagtggcagctac acatgtcaagcaggaagtgcagagaccagtgcaactgtgacagtgaaagagcttcctcca ttcttcaagaaagacttggtaagtgtggaggctgaggaagaaggtatagcctccctgtgc tgtgagctgtctaaacctggagtgttggtgcaatggaagaagaacaagctgccactaaga gcaaacaggaagtatgagatgaaacaagatggctgcctcctccagctccacatcaaggag ctcaaaccagaggacagtggcagctacacatgccaagctggaagtgcagagaccagtgcg actgtgacagtgaaagagctcacgccattcttcaacaaagaattacaaagtgtagagggt gaggagggagggacagcctctctgtattgtgaggcgtctaaacctggattgctggtgcag tggaagaagaataagatgccactgagagcaaacaggaagtatgagatgaaacaagatggc tgcctccttcagctccacatcaaggagctcaaaccagaggacagtggcagctacacatgc caagcaggaagtgcagagaccagtgcaactgtgtcagtgaaagagctccctgcattcttc aagaaagacttggtaagtgtggatgctgaggaagaaggtacagcctccctgtgctgtgag ctgtctaagcctggagtgtcagtgcaatggaagaagaacaagctgccactgagagcaaac aggaagtatgagatgaaacaagatggctgcctcctccagctgcacattaaggagctcaaa cctgaggacagtggcagctacacatgccaagctggaagtacagagaccagtgcgactgtg acagtaaaagaacatccaccatttttcaagaaggaattgcagaatgtgaaggctgaggaa gaaggttcagcctctctgtgctgtgaggtgtccaaacctgggctgtcaatacaatggaag aagaacaagctgccattaagaccaagcaggaagtatgagatgaaacaagatggctgcatc ctccagctccacatcaaggagctcaaacctgaggacagtggcagctacacatgtcaagca ggaagtgcagagaccagtgcaactgtgacagtgaaagagctcgctccattcttcaacaaa gaattacaaaacgtggagggtgaagatggagagacggcctctctgtactgtgaggtgtcc agacctggagtgtcagttcagtggaagaagaatagattgccattgagagccagcaggaag tatgaaataaaacaagatggctgcctccttcagcttcacatcaaggatctcaaacctgag gacagtggcagctacacatgccaagcaggaagtgcagagaccactgcaactgtgacagtg aaagagcttgttccattcttcaacaaagaattacaaagcatacagactgaggagggaggt acagtctccctgtcctgtgaggtgtccaaacctaggctgtcagtgcaatggaagaagaat ggactaccactaagagccaacagaaagtacgagatgaaacaagatggctgcctcctccag ctccacatcaaggagctcaaaccagaggacagtggcagctacacatgccaagcaggaagt gcagagaccagtgcaactgtgacagtgaaagagctcgctccatttttccacaagaactta caaaatgtggaggctgaggaaggaggtacagcttccctgtactgtgagctgtcaaaacct gggctgttggtgcaatggacgaagaacaagttgccactgagagcaaacaggaagtatgag atgaagcaggacggctgcctcctccagctgcacattaaggagctcaaacctgaggacagt ggcagctacacatgccaagctggaagtgcagagaccagtgcaaatgtgtcagtgaaagag cttcccccattcttcaagaagaacttacaaagtatagatgctgaggagggaggtacagtc tccctgtcttgtgaggtgtccaaacctgggctgtcagtgcaatggaagaagaacaagctg ccgctgagagcaaccaagaagtatgagatgaaacaagatggctgccttctccagctccac atcaaggagctcaaaccagaggacagtggcagctacacatgccaagcaggaagtgcagag accattgcgactgtgtcagtgaaagaactacaacctactccaccaaaggcagaaccgcca acattattacctcgatcgaagggcgctgcttccaaaacaacttctactccagagaacgag aagcctggcctcccagaggccaaacctgtgccaccagagcccaaaaagagaattaacagg aaagcattacctattacaaattcagaaaaagatgtggagccagtgttagatctaaaacag tgtgtggtgaaggagaataatgaagcccaaaaaggaatccaacctgtaaagcctgtggag aaagacttaaatgttgtacagaatataacacaactggagaggaataaagagaaagacagc gaggaacacgagaaagctgataaatcagtgagattactggagaaggatggcaggattgac atgaaggtcgaagagccaggtaggtctctggaaatcgacaatgaagttttcctggagaaa agacaacaagaaatgaatttggaggaatcaattgaagctggccttaaagtaaatcagtca gagaggattctgggtgacgctgtggctaaacaaaagaaacaaatattgatttgtccggaa atggaaaatgaagttgaacagagcttagaacaaccaggaaagcccttcgagaaaacaagt gaagttgagaagaaggtgaaacatccaggaacacagaccagtgaggatgaaaaggggcat ttgaaaccacaagaaaagttaattgcaaaagaaacaacaagggaacaagatgtaaagtct acagtaaagcaaagtgcagaagacaaggactatgtgcaacaacaagtgcccacagaggca gagagagagaaaaagccatttaaacaagtgtcatctgtaaatctcagggacaaacagtca gtggaacaacaagaaaagccttcagagagagaggctgattttgtccctccaaaaccacct atgaggatgaggagcaaagcaaaggggggaatggaaaagcaattatcaagggacacagag acggatcaagaaggacaagagctgactgaagttgtggtgaaaacaacagatgatcagcca gtgaaagagttgataagccctgtggaaaaagaggctaaagagaaacccatatttgagagg aaacagtcaataacaacagacagtgagatagatgggaaaataaaacctgtgaaaactgca gagaaagacacaaacaccaaacagctgatcaaacaaccagtaaaacccatgagaaaagaa cctgaagttgaccaggaaattaaactggcagttgagccaatgagaagggaggaacataaa cagacagtaaaaatggcagaagatgttccccttctctatatttctgaagatgaaactttc tcagaggctttgatcgagataccagcagaccacagcaaggtcctgcccgtcagctcttat actgacaggcaaactcaaccctctagtcctcctccaattaatgtgctccagaagagacaa ccgtccaaggatgttcctccggagactgacatcagcattgaggatgaaccacaaatgcaa gaggctgctgtcaagatccaggctgcctttaaaggctacaaaacccgcaaagaaatgcga cctgtctttaaagaggtgtttaagaaccagagtgcagatcttcatggtacagtcacttta gtgtgtattgtagagggaaaacccagcacagtgcgctggctgaaaaatggccatcaagtt gtcagtgaccaccgctgccgtattgagaccacagagcatggtgtgtgcacactggtgatc aaaaacctgaccaccagtgacggtggaatctatacctgtgaggtggtgaataagtttggt gtgacctcctacaacggaaacataacagtggtgcagcctcagcagcctgctcacactgcc cagaaacctgtacacccgccccttgcagcaataactcctctgcaacttgccccgacaaag cctgaggttcaggccaaaacaccaactcagaatctgcctcagactcaagcacagataccc acttcagctgcagatactgcgaactacgtagaaagtgtgaccatctccctgtgggaggcc tacaacctgacagagcaagatacaccaatgagtccacaagagaggagaggatcatcactc attgctgccagctccatgtcaagtccctctgattacgatacagctcctgacattatggaa ccagttgaaactggccccattgtaccaagggaagtaccaaaaccagaagaccaagtgtct ccaaaggatgaaaaagaagagacagctgctccacatccacctaagaaactactgaaggtc aaaggggctcatgaaggcaggatgaggacgccatctccaaagcaccatcgggcccacacg cccttagctagtactgtctctggatcagagtcagagggggaagaggatagacaagagaca tttgaaatgtatgtggctcgagctgactgcagtcctaacagtggaaataaggaaagtttt attctgaaggagggccagtttgtagaggtcctggactctgttcatcctgacagatggctg gtgaggaccaaacccaccaaaaccaaccctgctcgacagggctgggtatgtccagcctac ctggagaagaagagaaaggacactttcccacaaatgagagcacctcaagaagatcttgat ggaatagggtctacaggagaagagtacaggagagctctaagccaactggtccaaggcctg attgatggagaggaggagtttgtgaaggagatgaagatgttcacctctcaccagctgagt tatctggactccagtcgccagatccccatcaacatcctcaaccagaaagagatcattttc aggaatattaaggacattgtttctctgcatgagaggtccattcttcctggtctgaaaggc tgtgccacagatgatgatgtggccatgcacctggtcaagcacactgaagactttgagagg tatcttcactacatggtgggacaagcacaagcagaagcctgcatcactgacaaggccatg cagcagtatttcaaagaattaacagaatctggtaagccagatgcacctgtaatggatgtc ctcaccttcctccaacggccagtggagaggattcaaacctaccaggctttactaaaggag ttaatcaagaacaaagccagaagtggtcagagctgctgtctgttagaggatgccttctcc atggtgtcctgtctaccctggaggtcggacaacctgcaccaggtgtccctcatcgagaac tacccagctcctctgactgccctgggcgagcctgtgcgacagggagtcttcacagtgtgg gaggaatctccagaaattaaaacggcctctagagggcatcagagacaagtctttctcttc aaggagtgtattgtgctgtgtaaactgaaaagagacacccgcatgaacagtgacacctac accttcaagaacaaaatgaagctgaatgatgtggaaataaaggagtctgtgggtggagat gagaagtcttgggggttgtggcatgagcataggggctcggtgcggaggtacacactgcag ggccgctccacactggctaaactcccctggctcaaggacctgaaggagctccagcaacgc tccagcctgcccactaacagcccaccagtgttcgagtcactgttgtctgactgcaccaca aagataggacagacaattaaactgacatgcaaagtcacaggatcccccaaaccagtggtc acatggctaaaagatggtctccctctggaggatgacccccgtcacatcatcacagcagac cggttcggcacctgcagtctcatcctggacagtctcactgcagaggactctggacagtac acgtgctatgctacgagctccatgggcactgctggtactctggctaaggttgtggtccag gctccacccagatttgtgagtcgacttgaaagtgcttgtctgatagaaggagaggatatc cagttcacttgttccacactcagtactcctttaccacgagtcaggtggttgaaagatggt agagagctgactgacaagcaaaagtatttgatcttgaatgatgctcgaagtggaatcttg tgtctgacggtcatcagtgccacagaggcagatattggacagtatgagtgtgagctttgg aatgagcttggctgcgttaagtgcaaggcaggcttgtgccctgcttacgtaccaccgact gacatcgagaacgaccaaccacaggacttacctcctaaagatgcagactcagagggctgg tccactgcgtttgtgaagaaatggttacagactgacttcagccccacctctattgccaag atgcttttccctcctggataccctgaacaagcacagtgtaacactgaagagactgttctt gccgccacatccatggataacgtagctcagcagcctctgcgttacctggaggaagaggag gaggagatttacacctcagaagcaatgcaagagatcacagatgctcctccttcagtccag gtgtccactgaggacctgtgtgtagaacccggccaaacagccacatttactgccatcatc acaggaagacctactcctacgatacagtggtacaaggacgaagacgagcttgcagccaat gagaatgtgcagatagttcagcacggtgcccgttgctcactgaccatagggtgctgtgag ggtgaagacagcagcatatacacctgcttcgcctacaacgactctggccatgcctcatgc caggctcagcttacagtcgaggaaggcccactggagtgtcaggagagggaggtggaactg gggaagagaaggaagttattctctgtctatgatgtccacgaggaaattggaaggggaacg tttggggtagtgaagcgtgtagtccacagaaggacaggtgaagtctttgctgccaagttc ctgcctctgcggagcagcactcggacgagggccttccaggagagagacctgctctcccgc ctggctcatcccagagtggcctgtctgctggacttcttttgcaccagacgcactctggtg ctgattacagaaatctgctgttctcatggacttctggatcatttattactaagaggatca gtctcagagaaagaggttcagtcatacatccaacaaatcctcgagggtgttggtcacatt cacagcatgaacatcctgcatctggacattaaacctgataatatcctaatggtgtatccg cccaaagatgagattaagatctgcgacttcgggttttgccaagaaatagacatatccaga caccagtacagcatgtttggtacaccagagttcattgcaccggagattgttcaccaagaa ccggtcagtgtggccactgatatttgggctgtgggtgttatagcctatctgtgtctcgtg ggtcgatgcccttttgtaggagagacggaccgcacaacactgctgcgagtgggggagggg accctgaactgggatgcccctgatgtcacatacaggagcccagaggcccagaactttctc cacttggtccttcaaccagatccagagaagcgaccgtctgccttcgagtgcttgagccat gaatggttccaggacgaacatgcaggagaagacactgacgaaatcaacacaaggagtttg aaagtatttatctcaaagacaaaatggcagcgttctttgacctgcattgggtcagttctc acgttgaggcctgtccccgagctgttggacgctcccctcagagacactgcagtgacagtg cctcgggaactccaggagcacagcagcacctctctgagcagcggctcatcatctgagtac gatgaagctgactcttgggactttttccagcactacagcccgactgaggaggaggaggag acggaggaagattatgatcctttaatggagagagcacagatccctgagccttttgccaaa cttcacctggatgaagaagaagaggaggaaatgacactaggggaggaagaggacggggag atggtgggtagaaggagtgtactggagcggagtatgagcaggcagtcagtggcgtcgtca gatgtgtcatgccaacagacacctcagagggagcgtaggttcagtaaagacagcagtccg tctctccacctttctgactgggatgagggttcaggaagcgatggaggccgtatccctcgg ggcagcgtcatccgaagcactttctatagcacctctcatcagctctcacccatgtctgcc agacacatgacgctacgggacaaattccaggccaaaaagcaggagagaggccgcaaacca ctcaggagaagcgtttcaggacgcctcaacgagcctcttattgaatacgtggaggacgag acagaaactaaccgcggccagagacggggatctgtccagcccacgatgcagaagtcctgt tcctttgacagcggagttggcctcacccacagcaacataccccctcacaggagaagcagg tcccttgatgagtactcacgtcgctctcccagctcgcccaagcgcacgaaaccgggtgaa gaagaaggctctcaaagtctgaaagaagatttcacagatgacgaagtggcagggagaaac ttgttggccatcccgagcccgcggcgacccacaagaaggagaggctctgttgctcccata aatgggactggcacatctgttccctcaagcttactcgctggagacagaaggcaccaggct ggctcgggagccgacagagggagatacctttgccggctcccagggtctcttgctgagtcg tctattttggagcatggtggctcagagtcctcaagcagactcggttcctatgaggaactg agtcacggtcatctcagaggaagatacagatcaggagagagcgaagggtacgatgatcag ggtgagcctctgatctcatcatccccttcttcattccaggaagttaaacctagagactct tttccccaggcaccaccgcgaaaccgcacccgctccaaccccaacttatcctcaaacagc agagggcagctggggccatcgctaacgccgagccccagtcccagcctgtcctctctccag gctccagagagacctcccaggtccagggacaagaaggaaggccacggcctccagaggcac gcatccgctccggccctggaagtccgaccgcctacgggaaagtcacccaaactgggactg ttgaagatcttccgcaggcagtcttggactggccattcgtactctcagctggagaatgca gagttaggacccacattaggagagatcatgaagcctgatacacccaccatgtctctgagg aagaagatgagagcttcagcctctagcctgaccaagctgttttccaggtcttccagtaag gaggatgtgagtaaaggagggccaatagtaaagggagcagctcctgtcccacctgacaga gagcatggctctggtcttgagagtccaaaaaagaggacctccaaaatcctgccctctttc aaaatacctgcattcaaaaagacaaaagatctgccagtccgtcccaacaaagctgaggtg ctccacttagatgggggtggagtcttgctggtttggagaccagtccagtctaatgacccc atcacctactgtgtgcagtactgcacagatggtggggagtggacggtcctgtcagaggag gtgacagacagctgttatgtagtgaaggacttaccaagaggagcatcgtatgtgttcagg gtgggctgtatcaccaagaaaggagcaggacctttcagtgatgcttcagcacctgttgtt atggccactcaccctgaagagactcacgtttctctcatccagactgagaccttggggtca aaggtcactggatcagaaggacaaacaacacaaaagaactacaacttcctctctgagatc aacaggggtcgtttcagcgtagtaaccctgtgtagagatgttgaaacaagccaagtgttt gctgccaagatcaccccctaccaggcagagcagaggcagttagtgctgagggagtaccag ctgctgaggaggcttcatcacccgcacctggtgcagctgcacaacgcctacctcaccacc cactacctggtgttagtggaggagctttgccctggcaaagagctgctctacagtctggct gcgagagatctgtacgcagagactcacgtcgcagagctgctggttcagattctgagcgca gtcgactacctccacagtcgtcgaatcatccacctggacctgaagtctgacaacatgctg gtggatgatggcaaccacgtgaagattgtagactttggttcggctcagtccttcacacct ggacagcccctcaccatcgagcacatccacggcctgtcagagagcaaagagtgccgcacc aaagtttatattgtccttcctaaagctccggaaatcctggagggtcagggagtcgggcct gaaactgatgtttgggctattggagttctgtcattcatcatgttgagtgccgacagcccg ttccacgcggagcacagctgggagcaagacagaaacatcaagaaggggaagatccagttt ggacgctgttaccctggtctgtcagagggagccttaaccttcatgaagagcagcctcaat aacaaatcctgggggagacccactgcagctgagtgtctccagaacccgtggctgcgtgct catcgtgtcccacacaaaacccgaccctccaaggtgtgtttctccacagacaagcttaaa gcttacctccagcagaaggaggagaaacgagacctggtccacatcaaacttcagggtccc ttcttccagtga

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