Lates calcarifer (barramundi perch): 108891100
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Entry
108891100 CDS
T04895
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
lcf
Lates calcarifer (barramundi perch)
Pathway
lcf00270
Cysteine and methionine metabolism
lcf00480
Glutathione metabolism
lcf01100
Metabolic pathways
lcf01240
Biosynthesis of cofactors
lcf04216
Ferroptosis
Module
lcf_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
lcf00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
108891100
09106 Metabolism of other amino acids
00480 Glutathione metabolism
108891100
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
108891100
Enzymes [BR:
lcf01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
108891100
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Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
108891100
NCBI-ProteinID:
XP_018543746
UniProt:
A0A4W6DZN7
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Position
LG16_LG22:7024818..7033434
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AA seq
630 aa
AA seq
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MGLLSQGSPLNWDESKKYADHVRKHGIIQFLNIYNKVKDRQRDVLKWGDEVEYMLVELDD
KDEKVRLVLNGGDVLDTLQDQGENINPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EGNMGKRRREASSVLNQNETLCTITSFPRLGCPGFTKPEHRPTPVEKGASKSLFFPDEAI
NRHPRFSALTRNIRHRRGEKVAINVPIFKDKCTPFPFVEEFLEDDGEAARAALPDHIYMD
AMGFGMGNCCLQVTFQACSIDEARYLYDQLATFCPIVMALSAASPFYRGYVSDIDCRWGV
ISASVDDRTQEERGLKPLKNNKYRIFKSRYDSIDSYLSSCGEKYNDIDLTIDKEVYEQLL
SAGIDKLLAQHIAHLFIRDPIYVFKERIHLDDENEADHFENLQSTNWQTMRFKPPPPNSD
IGWRVEFRPMEVQLTDFENAAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQMRNAV
QEGMFYFRKDIFKGCNPVLDGTPSAQNGLETDGANEEYTLMSIDTIINGKEGVFQGLIPI
LNCYLENMEVDVDTRCTILNYLKLIKKRASGDLMTMAKWMREFVAKHPQYKQDSVITDKI
NYDLFRKCDRIAKGEEQCPELIGNPVNKFK
NT seq
1893 nt
NT seq
+upstream
nt +downstream
nt
atgggtttactgtcacagggctctccactgaactgggacgaaagcaagaagtatgctgac
cacgtgagaaagcacggcatcattcagtttctcaacatctataacaaggtgaaggatcgt
cagagagatgtgctgaaatggggcgatgaggttgagtacatgttggtggaactggatgac
aaggatgagaaggttcgacttgtgctgaacggtggagatgttttggacacactccaagac
cagggtgaaaatataaaccccaatcaccccacgctctggagaccagaatatggcagctac
atgattgagggaactccagggcagccgtacggcgggacaatgtcagagttcaacaccgtc
gagggcaacatggggaagagacgacgagaggcctcatctgtcctgaaccagaacgaaacc
ctctgcaccatcacctcatttccaaggttaggttgcccaggtttcaccaaaccagagcac
cggccgactcctgttgagaagggagcatcaaagtcactgttcttcccagatgaagccatc
aacagacacccaagattcagcgcccttaccagaaacatacgtcacagaagaggagagaaa
gttgcgattaatgtgccaatcttcaaagacaagtgtactccatttccatttgtggaggag
tttcttgaggacgacggtgaggcagcgagagcggctctgcctgatcatatctacatggac
gccatgggctttggcatgggcaactgctgtctgcaggtaacattccaggcttgcagcatt
gatgaggcaaggtacctttatgaccaactagcaactttctgccccattgtgatggcattg
agtgcagcctcacctttctacagaggctatgtgtcagatattgattgtcgctggggagtt
atttctgcctcggtggatgacagaacacaggaggaacgcgggctgaagcctttgaaaaac
aacaaatacaggatcttcaagtcaagatatgattccattgacagctacctgtctagctgt
ggtgagaagtacaatgacattgatctgacgatagacaaagaggtctacgagcagctgctc
agcgcaggaattgacaagctgctggcccaacacattgcacacctcttcatccgagatcca
atctatgtcttcaaggagagaatacatttggatgatgaaaatgaggctgatcactttgag
aacctccagtcgaccaactggcagacaatgaggtttaaacctccacctccaaactccgac
attggctggagagttgagttccgccccatggaggtgcagctaactgactttgaaaatgct
gcatatgtggtctttgttgtcctgctcaccagagtgatcttgtcctacaagctggacttc
ctaatccctttgtcaaaggttgatgaaaacatgaaggtcgcacagatgagaaatgcagtc
caggagggcatgttttatttccgaaaggacatcttcaaaggctgcaacccggtccttgat
ggtaccccttcggctcagaatggcttggagactgatggtgctaatgaggagtacactctg
atgagcatcgacaccatcatcaatggaaaggagggggtttttcaggggcttatcccaatc
cttaactgctatctggaaaacatggaagttgatgtggacaccagatgcaccattttgaat
tatctgaagctcatcaagaaacgtgcctcaggtgacctgatgaccatggccaagtggatg
agggagtttgtcgcaaagcacccgcagtacaagcaggacagcgtcataaccgacaagatc
aactatgacctgttccgaaagtgcgacaggattgcaaaaggcgaagagcaatgcccggag
ctcatcggaaacccagtaaacaagttcaaataa
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