KEGG   Latimeria chalumnae (coelacanth): 102345110
Entry
102345110         CDS       T02913                                 
Symbol
PLCE1
Name
(RefSeq) phospholipase C epsilon 1
  KO
K05860  phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
Organism
lcm  Latimeria chalumnae (coelacanth)
Pathway
lcm00562  Inositol phosphate metabolism
lcm01100  Metabolic pathways
lcm04020  Calcium signaling pathway
lcm04070  Phosphatidylinositol signaling system
Module
lcm_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:lcm00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    102345110 (PLCE1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    102345110 (PLCE1)
   04070 Phosphatidylinositol signaling system
    102345110 (PLCE1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:lcm04131]
    102345110 (PLCE1)
Enzymes [BR:lcm01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     102345110 (PLCE1)
Membrane trafficking [BR:lcm04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    102345110 (PLCE1)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    102345110 (PLCE1)
SSDB
Motif
Pfam: PI-PLC-X PI-PLC-Y RasGEF RA C2 EF-hand_like GDPD
Other DBs
NCBI-GeneID: 102345110
NCBI-ProteinID: XP_005991625
Ensembl: ENSLACG00000017509
LinkDB
Position
Un
AA seq 2262 aa
MPNIFSVTNKAEVFDDCNAEESWDRKACISASILDCHNINNCNAKPQNCKDSLSYNQLCQ
PCDSLQDENICFRPAIPSSLHRQEFDENAQKSEMEGFSMEVRSFADQTEREKTVKHLPYC
LHNSTDFSFNHNYARYISKNLCTGQNSLILGSIMPLGQEVHDGATIVCSCKPVDFTKTST
NATGKQHYNSCQGIKTRYPGFERTHQKMKCSIHNSCGDNVSDRQSGKLTISHFEECNNSF
EEGIEDEFARNKKERSTLLIRRFCKNNREVKKSIYSGTRAIMNTLPSGHIGTKAWKGIYL
KRHCLCDFKRCRTTAEHLTIVQILIGRQQGFSHQLAKSIWCQVKYGSVYDISNMVSVPEL
QKIDVVHNVLREEAEKALDYLLHSSRKLLASVVVCRKGDNCSSIKPCAKQALNDYRATLH
RTAISDYITGALLEATTSLGARSSIPNPIGGSAGRMLKERQVYTTMAGSNTLPSNVTGIS
KELTDLRHLIQFPEEIASILTEQEQELYRKVLPLDYLCFLTRDLTNPDNQSTPSSPLSSF
PASALITENGEHNAVEDLVTRFNEVSSWVTWLILTAGSMEEKREVFSYLVHVAKCCWNMG
NYNAVMEFLAGLRSRKVLKMWQFMDQSDIETMRSLKDAMAQHESSSEYRKVVNRALNIPG
CKVVPFCGVFLKELCDVLDGAASLMRLCPRYNSHDEAIEFVSDFNGQDNFLQRVGKDGLS
NPEKESTVNNILQTIRSCNRNLEAEEGEESFSEGSSSRKNSVKDKNKNQFIVGDLSDSEG
DIFEQSREWEVQGVEDQKRAFSHGTELIPWYVLSIRADVHQFLLQGATVIHYDQEAHLSA
RCFLKLQPDNCTLTWTKQTATCFVNPKMKGAVLGSSGELGHNKYQFCGQIVLNGLVEGFL
DLCAVKAVYMGHPGIDMHTVCVQNKLCNMALEENGVTLLYGLHTTDNKLLHFVAPTYTAK
MLYDGLLELASAVRKMKKFPDQRLQWLRKQYVSLYQEDGKYEGPTLAQAVELFGGRRWIT
RNTSTGTLPKSTEKPNVQRNNTLGINTAKKKKKVLMRGDSGDATDDEMATRKSKSYARGR
SGSDPPDLDEQESDQNIVAYSPVSYTLPSRRAHSLTTSGSPSLAPAGSTPTRPASSPILS
ASSKGQASTWSCRSWHGRVKGGLKGFQNFMVSDSNMSFIEFVELFKSFSVRSRKDLKDLF
DVCSVPCNRSGSESAPLYTNLTIDDNISGLQPDLDLLTRNVSDLGMFIGSKQQRSDNQRQ
ISDAIAAASIVTNGTGVESTSLGVFGMGIQQLNDFLVNCQGEHHTYDEILSIIQKFEPSE
SMCQQGLMSFEGFARFLLDKDNFASKNEDLQINVEEMQYPLSYYYIESSHNTYLTGHQLK
GESSVELYSQVLLQGCRSVELDCWDGDDGMPIIYHGHTLTTKIPFKDVVEAIDRSAFINT
DMPVILSIENHCSLPQQRKMAEIFKSVFGDKLVTKFLFESDFSDDPMLPSPWQLRRKILL
KNKKLKAHQTPVDILKQKAHQLASMQAQAGNGNPAGCSSTNNEDDDDEEDEYDYDYESLS
DDNILDDRPESKSSSDKLQFEYSEETPKRIKKADSTIHSKGKVYDMELGEEFYLPQNKKE
SRQIEPELSDLVIYCQAVKFPGLSTLNPAGSSRGKERKSRKSIFGTNPGRMSPGETTSLA
KASGKGSFDGTRQNWEEPTSAPFNPTTSLSAIIRTPKCYHISSVNENAAKRLCRRYSQKL
IQHTTCQLLRTYPAATRIDSSNPHPLIFWLHGIQLVALNYQTDDLSLHLNAAMFEANDGC
GYVLKPPVLWDKNCPKYQQFFPLERDVENMGPAIYSLTVISGQNVCPSNSNGSPCIEIDV
LGMPLDSCHFRTKPIHRNTLNPMWNEQFLFHVYFEDLVFIRFAVVENNSSTVTAQRIIPL
KALKRGYRHLQLRSLHNEPLEISSLFIISRRMEENPSGNIVPASVLFSTEERRALNVIKV
TIHGLPGPEPFTVLSITEKTTAWKLLHQILATNKGPEYDVGDYYLLEEKIFLSKEKNDCR
KPPFQRVIGPEEEILKILNSWFPEEGYVGRIIFKTKEENLNAKNSLNDGKEDVNTLTEDD
SFFVQVHDVSPEQPRTVIKALKFSTAQDVIQQALSKAKYSYSILNNPNPSDYVLLEEVTK
EPANKKSSASKPTQRVLSDHESVFQAQSRWKGAGKFILKLKEQIARDDKRKGISFTSELK
KLTKSSKQSRNVSSLLQVTSSESAMSKDEKPACSVSFSEITD
NT seq 6789 nt   +upstreamnt  +downstreamnt
atgcccaatattttttctgtgacaaataaagcagaagtatttgatgactgtaatgctgaa
gagtcttgggacagaaaagcatgtatttcagcgtcaatattagattgtcacaacatcaac
aactgtaatgctaaaccccaaaactgcaaggacagcttatcatataaccagctatgccag
ccatgtgactccctgcaagatgaaaacatatgctttaggcctgcgattccttcttcattg
cacaggcaagagtttgatgaaaatgcacaaaagtctgaaatggaagggttttcaatggaa
gtgaggtcatttgctgatcagacggaaagagaaaaaactgtaaaacatttgccttattgt
cttcataattcaactgacttcagttttaaccataattatgcgaggtatatatcaaaaaat
ttgtgtaccggacagaacagtttaattttgggcagtataatgcctcttggtcaagaggtt
catgatggtgctaccatagtctgtagctgcaagccagtggacttcacaaaaacaagcaca
aatgcaactggaaaacaacattataatagctgtcaagggataaaaactagatatccaggt
tttgaaagaactcatcagaagatgaaatgctcaattcataactcctgtggagacaatgtt
tctgacagacagtcaggaaaactaaccattagccattttgaagaatgcaataatagcttt
gaagaagggatagaagatgagtttgctagaaataaaaaagaacgctccactctgctgatc
agaagattttgtaaaaataatagggaggtgaagaaatccatttactctggcacaagagca
ataatgaataccttgccttctggacacattggaacaaaggcttggaaaggtatttacctt
aaaagacattgcttgtgtgattttaaacgttgcaggactacagctgaacatctcacaata
gttcaaatcctaattggaagacagcaaggtttcagccatcagctagcaaagtccatttgg
tgtcaggtgaaatatggatcagtctatgatatcagtaacatggtcagtgtacctgaatta
caaaaaattgatgtggttcataatgtgctgagagaagaggcagaaaaggctcttgattac
cttctccattcttcgagaaagctcctagcatcagtagtggtctgcagaaaaggtgataac
tgctcttctataaagccatgcgccaaacaggctttgaatgattatcgtgctactctacac
agaactgccatctctgattatatcactggtgctctgctagaagcgaccacatctttgggg
gcaaggagcagcattccaaatcccatcggagggtcagctggaagaatgcttaaagaacga
caagtgtatacgacaatggctggttcaaataccttgccctcaaatgtaactgggatcagc
aaggagttgacagatctgcgtcacctaattcagtttcctgaggagattgccagtattctc
actgaacaagaacaggaactctaccgcaaagtcttacctcttgactacctctgctttttg
accagggatttgacaaacccagacaaccagagcacaccctcgtctcctttaagttctttt
cctgcatctgctcttattacagaaaatggtgagcataatgccgttgaagatctggtaaca
agatttaatgaggtgagttcttgggtgacatggctgatactgactgcaggctctatggaa
gagaagagagaagttttttcatacttggtacacgtggcaaagtgctgctggaacatgggc
aattacaacgctgtaatggaattcctggcaggactcaggtctagaaaagtcctaaagatg
tggcagtttatggaccagtctgacattgaaactatgcgaagtctgaaagatgctatggca
caacacgaatcatcatcagaatacagaaaagtagtgaacagggctctgaatatccccggc
tgtaaggttgttcccttctgtggagtatttttaaaagaactctgtgatgttcttgatgga
gctgccagtctcatgagactctgtccacgatataattcccatgatgaagcaatagagttt
gtttcagattttaacggtcaggacaattttctgcagcgagtaggaaaggatggtttgagc
aaccccgagaaagaatcaacagtaaacaacatcctgcagactattcgaagctgcaatcga
aacctagaagcagaagaaggagaagaaagctttagtgaaggcagcagttcaagaaaaaac
tctgtaaaagacaagaacaaaaaccagttcatagttggagacctgtcagactcggaaggt
gacatatttgaacaatcaagagaatgggaagtacaaggagttgaagaccaaaagagggca
tttagtcatggaactgaactcattccttggtatgttttgtcaatcagagctgatgtccat
cagttccttctccaaggggccacagtaattcattatgaccaagaggcccatctttctgct
cgttgttttcttaaacttcaacctgacaattgcactttgacctggaccaagcaaactgct
acctgttttgtcaatccaaaaatgaaaggtgctgttcttggtagcagtggggagcttggt
cacaacaagtatcaattctgtgggcaaattgtactaaacggacttgtggaaggcttcttg
gatttatgtgccgtaaaggcagtttacatggggcatccaggcatcgacatgcacactgtg
tgtgttcagaataaactttgtaacatggcattggaagagaatggggtgacattactctat
gggcttcatactactgataacaaattgttgcactttgtggctcctacatacactgctaaa
atgctgtatgatgggctgcttgaactggctagtgctgttaggaaaatgaagaaattccct
gaccagaggctgcagtggcttcggaagcagtatgtcagcttatatcaggaagatggtaaa
tatgaaggaccaactttggctcaagctgttgaactttttggaggcaggcggtggattaca
agaaacacaagtacaggaacattgcctaagagtactgagaaacccaatgtacaaaggaat
aatactctgggaataaacactgccaagaaaaagaagaaagttctcatgaggggggacagt
ggggatgctactgatgatgaaatggcaactcgcaagtcgaaaagctatgctcgtggtaga
agtggttctgatcctccagacttggatgagcaggagtcagatcagaatattgttgcatat
tcccctgtctcctacactctgccatctagaagagcccattccctcactacctctgggtct
cctagcttagcacctgcaggatccacaccaactagacctgcctcttctcctatcctgtca
gcatctagcaagggccaagctagtacatggagctgtcgaagttggcatggtcgagtaaag
gggggactgaaaggctttcagaacttcatggtatctgacagtaacatgagctttattgaa
tttgtggaactttttaagtctttcagtgtacgaagtcggaaggacctcaaggacctgttt
gatgtctgttctgtaccatgcaatcgctccggttctgagtctgccccactttatactaat
ttaaccatcgatgacaacatcagtggtctgcagccagatttagacttactgacccgaaat
gtatccgatctgggtatgttcattggaagcaagcagcagagatcagacaaccagagacag
atctcagatgccatcgctgctgccagtattgttactaatgggacaggagttgagagtaca
tcgttaggagtgtttggaatgggcatccagcagcttaatgactttctggtgaactgccaa
ggagagcaccacacctatgatgaaattctcagcatcattcagaagttcgagccatctgag
agcatgtgtcagcagggacttatgtcatttgaaggatttgcgaggtttctactggataag
gacaattttgcatcaaagaatgaagatttacaaataaatgttgaagagatgcagtaccct
ttatcatattattatattgaatcctcacataacacatacctcacagggcatcagcttaaa
ggagagtcttctgtagagctttatagccaggtgctattgcaaggttgcaggagtgtggag
cttgactgctgggatggggatgatggcatgcctatcatttatcatggacacacacttaca
acaaaaattccatttaaggatgtggtagaagctattgaccgcagtgcctttatcaacact
gacatgccagttatcttatcaatagaaaaccactgttccctacctcaacagcgcaaaatg
gctgagatttttaagagtgtatttggggacaagcttgtaactaagtttttgtttgaaagt
gacttctctgatgacccaatgctcccctctccctggcaacttagaagaaaaatattgttg
aaaaacaagaaacttaaagcacaccaaactccagttgatatactgaaacaaaaagctcac
caactagctagcatgcaagcacaggccggcaatggcaaccctgctggttgcagctcaact
aataatgaagatgatgatgacgaagaagatgaatatgattatgactatgaatctctgtct
gatgacaatattcttgatgatcgacctgagagcaagtcatcaagtgacaagttgcaattt
gaatatagtgaggaaactccaaagagaattaagaaagcagacagcactatccacagtaaa
ggaaaggtatatgacatggaattgggcgaagaattctaccttccacagaacaagaaggaa
agtaggcaaatagaaccagaactatctgacctggtcatctactgccaagctgtcaaattt
ccaggcctgtcaactctaaacccagctggatctagcagaggaaaagaaagaaaaagtaga
aagtctatctttggcaccaatcctggcagaatgagccctggggaaactacatcactcgcc
aaagcatctggaaagggttcatttgatggtacgcggcaaaactgggaggagcccacctct
gctccttttaatcccactacctctctgagtgctatcattaggacgcctaaatgttatcac
atctcatcagtgaatgagaatgctgcaaagcgcctctgcaggaggtattcccagaaactg
attcagcacaccacttgccagctgttgagaacctaccctgcagctactcgcattgactct
tcgaaccctcatcctcttatcttctggcttcatgggatacaactggttgctctcaattac
cagacagatgatctttctttacatttaaatgcagctatgtttgaagctaatgatggttgt
ggctatgttttgaaacctccagttctatgggataagaactgcccaaagtatcagcaattt
tttcctctagaacgagatgtagaaaatatgggaccagcaatctattctctaacggtaatt
tctggtcagaatgtatgtcccagtaacagtaatgggagcccatgtattgaaattgatgtg
ctgggaatgcccctggacagttgtcacttccgcactaaaccaattcatcgtaataccttg
aatcctatgtggaatgagcagttcctgtttcatgtttactttgaagatcttgtcttcata
cgatttgcagtagtggaaaataacagctcgacggtaactgctcagagaatcataccatta
aaggcactgaaaagagggtacaggcacctgcagctaagaagcctccataatgaaccttta
gagatttccagtctgtttataattagtagaagaatggaggaaaatccaagtgggaacatt
gtacctgcctcggtgctgtttagtacagaggagagaagagctctcaatgtgattaaagtt
acaatccatggacttcctggacctgaaccctttactgttctcagtatcactgaaaagacc
acagcatggaagcttcttcaccagatcttagccacaaataaaggccctgaatatgatgtt
ggagattactatttactggaagagaagatattcctatctaaagagaagaatgattgcagg
aagcctccattccagagggtgattggtccagaagaggagatcttaaaaattcttaacagc
tggttcccagaagaaggctatgtgggaagaattatctttaaaaccaaagaggaaaatttg
aatgcaaaaaactctctgaatgatggaaaagaggatgtgaatactttaactgaagatgat
agcttctttgttcaggtgcatgatgtttctccagaacaacctcgcactgtaattaaagct
ctcaaattcagcacagctcaagatgtcattcaacaggctctcagcaaagccaaatactcc
tacagcattcttaacaatcctaatcccagtgactatgtccttttggaagaggtcactaag
gaaccagcaaacaaaaaatcttcagcatccaaaccaactcagcgggttctctcagaccat
gaaagtgtgtttcaggcgcagagcagatggaaaggagcggggaagtttatcctgaagcta
aaggagcagattgcacgagatgacaagaggaaaggtatatctttcaccagtgagctaaag
aagttaaccaaatcaagtaaacaaagtagaaacgtctcctcactgctccaagtgacatct
tcagaaagtgccatgagtaaggatgagaaacctgcatgtagtgtgtccttcagtgaaatc
actgattaa

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