Latimeria chalumnae (coelacanth): 102354933
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Entry
102354933 CDS
T02913
Symbol
POLE
Name
(RefSeq) DNA polymerase epsilon, catalytic subunit
KO
K02324
DNA polymerase epsilon subunit 1 [EC:
2.7.7.7
]
Organism
lcm
Latimeria chalumnae (coelacanth)
Pathway
lcm03030
DNA replication
lcm03410
Base excision repair
lcm03420
Nucleotide excision repair
Brite
KEGG Orthology (KO) [BR:
lcm00001
]
09120 Genetic Information Processing
09124 Replication and repair
03030 DNA replication
102354933 (POLE)
03410 Base excision repair
102354933 (POLE)
03420 Nucleotide excision repair
102354933 (POLE)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
lcm03032
]
102354933 (POLE)
03400 DNA repair and recombination proteins [BR:
lcm03400
]
102354933 (POLE)
Enzymes [BR:
lcm01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.7 Nucleotidyltransferases
2.7.7.7 DNA-directed DNA polymerase
102354933 (POLE)
DNA replication proteins [BR:
lcm03032
]
Eukaryotic type
DNA Replication Elongation Factors
DNA polymerase epsilon complex
102354933 (POLE)
DNA repair and recombination proteins [BR:
lcm03400
]
Eukaryotic type
SSBR (single strand breaks repair)
BER (base exicision repair)
Long Patch-BER factors
DNA polymerase epsilon complex
102354933 (POLE)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DUF1744
POL2_thumb
DNA_pol_B_exo1
zf_DPOE_2
zf-DPOE
DNA_pol_B_exo2
DNA_pol_B
RNase_H_2
APP_N
Motif
Other DBs
NCBI-GeneID:
102354933
NCBI-ProteinID:
XP_005993379
Ensembl:
ENSLACG00000017229
LinkDB
All DBs
Position
Un
AA seq
2253 aa
AA seq
DB search
MVLQNSGRLKPESKGRWDTENQQDDGANLSALKRLERSQWTDEMDGRFGFERLKEPGEKT
GWLINMHPTEILDEDKRMISAVDYYFLQEDGSRFKVALPYKPYFYVATRKGCEREVSSFL
SKKFQGKISKLETVPKEDLDLPNHLVGLKRNYIKLAFNTVDDLVKVRKDISPAVRRNKER
DNSRDAYTTMLSSALAGTSVTTEEGGTSKKMADQMDNIIDIREYDVPYHVRLSIDLKIHV
AHWYNIRNRGSSYPPEIARRDDLVERPDPVVLAFDIETTKLPLKFPDPESDQIMMMSYMI
DGQGYLITNREIVSEDIEDFEFTPKPEYEGPFCVFNEPDEAKLIQRWFEHVQETKPNIFV
TYNGDFFDWPFVEARAAVHGLNMYREIGFQKDSQGEYKSTQSIHMDCLRWVKRDSYLPVG
SHNLKAAAKAKLGYDPVELDPEEMCRMATEEPQTLATYSVSDAVATYYMYMKYVHPFIFA
LCTIIPMEPDEVLRKGSGTLCEALLMVQAFHANIIFPNKQQQVFNKLTDDGHVLDSETYV
GGHVEALESGVFRSDIPCRFKMNPAAFDFLLQRIEKTLHHAIEEEENIPLEQVTNLQEVC
DEIKKKLTCLKEVPNRIECPLIYHLDVGAMYPNIILTNRLQPSAMVDEATCAACDFNKPG
TTCQRRMAWQWRGEFMPATRSEYHRIQQQLESEKFPPIFPNGPPQAFHALSREEQAKYEK
KRLADYCRKAYKKIHITRIEERVTTICQRENSFYVDTVRAFRDRRYEFKGLHKVWKKKLS
AAMESGDASEVKRCKNMEILYDSLQLAHKCILNSFYGYVMRKGRPLELDTDGIWCVLPNS
FPENFVIKSTNAKKPKVTISYPGAMLNIMVKEGFTNDQYQELVDPTSLTYISRSENSIFF
EVDGPYLAMILPASKEEGKKLKKRYAVFNEDGSLAELKGFEVKRRGELQLIKIFQSSVFE
AFLKGTTLEEVYASVAKVADYWLDVLYSKAANMPDSELFELISENRSMSRKLEDYGEQKS
TSISTAKRLAEFLGDQMVKDAGLSCRYVISKKPEGSPVTERAIPLAIFQAEPSVRKHYLR
KWLKSPSLQEFEIRSILDWDYYIERLGSAIQKIITIPAALQQVKNPVPRVRHPDWLHKKL
LEKNDVYKQKKINELFSSEGKRQITSNQPVESSQQSEIADMEDLGAPKRLQPSIPIASKR
KRVVAGGQSQEESQDLELTQSWREILGPPPPIGSTKDERLVWLRYHKKKWELQARQRKER
RKKRRLEDGEAVTGGGGIIRDTLTTGLGSFLRRTARTILDMPWQLVQIAETNQPGLFKLW
AVIGSDLHSIKLNIPRVFHVNQRIPKLEESTAYRKVNRILPRSNVVYNLYEYSVPEDMYQ
EHINEINADLSAPDIEGVYETQIPLLFRALVQLGCVCMVNKQLIRHLAGREAETFELEHL
EMRSLAQFAYLEPGSIRHIYLYHNSQGNKALFGLFIPSQRKVSVFVVDTVRSNQMPNLNN
MYSVERTAMLEKVDEELLPPDKHSFEIRAETDLKTVYRAIQRLLLNYKDERRGPTLIAIQ
SNWDLKRLSNGMPVFEEFPLVPVHIIDEISYNVLDWQRHGARRMIKHYLNLDSCLTQAFE
MARYYHIPVGNLPEDISTFGSDLFFSRHLRRHNHLLWLSPNSRPDLGGKEMDDNRLVMEF
DEKVSVEINNPGCYSTVCVELDIQSLAVNTILQSHHINDMEGASSVGISFDVIQQASLED
MVTGNQTNTLASYDETALCSNTFRILKSMVVGWVKEITQYHNVYADNQVMHFYRWLRSPS
SLLYDPALHRMLHNMMKKLFLQLVAEFKRLGSSIVYGNFNRIILCTKKRRIEDAIGYVEY
ITNSIHTREIFHSLTISFSRCWEFILWMDPANYGGIKGKLPSSIMYGETEKKKGEEGSED
EEEEAVDPDEDSAGEDDVEELLENNWNIMQFLPQEASCQSYFLMIVSAYIVAVYHSMKEE
MRRNAPGSTPVKRRGASSQVSQESEGDAGALPGMITFSQDYVSNELTQNFFTITQKIQKK
VTGTRRATEPSEMFPVLPGSYLPLNNPALEFIKYVCRALSLDMNITNQVNKLKRDLLRLV
DVGEFSEEAQFKDPCQSYILPEVICRHCNFCRDLDLCKDPSMAQDGTVLPSWLCTNCQAE
YDSGSIEMALVEAVQKKLMAYTLQDLVCTKCKGIKEANMPIYCSCAGDFDLTISKKGFSE
QMKVFRKIAHHYGMPFLLETIEWLVQMNPPICT
NT seq
6762 nt
NT seq
+upstream
nt +downstream
nt
atggttctgcagaacagcgggcggctgaagcccgagtccaagggccgctgggacactgaa
aatcagcaggatgatggtgctaacctatcggctctcaaacgccttgagcgcagtcaatgg
acagatgagatggatggccgttttggatttgagaggctgaaagaacctggagaaaagaca
ggatggcttatcaacatgcatccaactgagatcctggatgaggataagcgaatgatcagt
gcagtggattattattttcttcaggaagatgggagcaggtttaaggttgcattaccctat
aaaccatatttttatgtggccacaagaaagggatgtgagagggaggtgtcctcttttctc
tctaagaagtttcaggggaagattagcaaattggagactgttcccaaagaagacctagat
ctgcccaatcacctggtgggcctgaagagaaattatatcaaactggcctttaacactgtg
gatgatctggtgaaggtgaggaaggacatttcccctgctgtcaggaggaacaaagagagg
gacaactcaagggatgcctatactaccatgctctccagtgctctggctggcaccagtgtc
acaactgaagaaggaggtacctccaagaagatggctgatcagatggacaatatcattgat
attcgggagtatgatgttccttaccatgtcagactgtcgattgaccttaagatacatgtg
gcccattggtacaacatccgcaatcgtgggagttcctaccctcctgagatcgctcgcagg
gatgatctcgtagagcggccggatccggtagttttggcatttgatattgaaaccactaag
cttcctctgaaattccccgatccagaatctgatcagattatgatgatgtcatatatgatt
gatggacagggttacttaatcacaaaccgtgaaattgtatctgaggatattgaagatttt
gaatttactcccaagccggagtatgaagggccattctgtgtctttaatgagccagatgag
gcaaaattaattcagaggtggtttgagcatgttcaggagacaaaacccaacatctttgtg
acttacaacggtgatttttttgactggccatttgtggaggctcgtgcagcagttcatggg
ttaaacatgtacagagaaattggatttcagaaggacagccaaggggagtacaaatctact
caaagtattcacatggactgtctcaggtgggttaagagagacagctacctgcctgttgga
agccataatctaaaagcagcagccaaagctaaactgggttacgatccagttgaactggac
ccggaggagatgtgtcgaatggctacagaggaaccacagactttagcaacctactccgtg
tctgatgctgttgctacttactacatgtacatgaagtatgtgcaccctttcatctttgct
ttgtgtaccatcatccctatggaaccagatgaggtgttgaggaagggttctgggacactc
tgtgaggcactgctgatggtccaggcatttcatgccaatatcatcttcccaaacaagcag
cagcaggtcttcaacaagctaaccgacgatggacatgtgcttgactcggagacctatgtc
ggaggacatgttgaggcactggaatccggggtctttcgtagtgacatcccttgtcgcttc
aaaatgaatccggcagcttttgacttcttgctgcagagaattgagaagacgctgcaccat
gcgattgaagaggaagagaacatcccactagagcaggtcaccaacttgcaggaggtctgt
gatgaaattaagaaaaagctaacctgtctcaaggaggtgccaaatagaattgagtgccct
ctcatttatcacttggacgtaggggccatgtaccctaatatcatcctaaccaatcgatta
cagccttcagctatggtagatgaagccacgtgcgctgcctgtgattttaacaagccaggg
accacttgtcagcggagaatggcatggcagtggagaggagagtttatgccagctacccgc
agcgagtaccaccgcattcagcaacaactggagtcagaaaagtttccacctatttttcca
aatggcccccctcaggcattccatgcgctgtcccgggaagagcaggccaaatatgagaag
aaacgcctggcagattactgtcggaaagcatataagaaaatccacatcacccggattgag
gagcgagtgacaactatttgccagcgggaaaactccttctatgttgacacagtgcgagcg
ttcagagatcgcagatatgagttcaaagggctgcacaaggtttggaagaagaagctgtcg
gcagccatggagagtggagacgcatcagaagtgaaacgctgtaaaaacatggagatccta
tatgactcccttcagctggcacacaagtgtatcctcaactctttttatggctacgtcatg
agaaaagggagacccctggagttggacactgatggtatttggtgtgtccttccaaactct
tttccagaaaactttgtaatcaagtcaaccaatgccaaaaaacctaaggttacaatctcc
tacccaggtgccatgctcaacattatggtaaaggaaggcttcactaatgatcagtatcag
gagctggtggacccaacctcacttacctacatctcccgctctgaaaacagcattttcttt
gaagtcgatggcccataccttgccatgattctccctgcctctaaggaggaaggaaagaag
ctaaagaaaaggtatgccgttttcaatgaggatggctccctggcagagctgaaaggtttt
gaggtaaagcgccgaggtgaattgcagctgattaagatttttcagtcttccgtgtttgag
gccttcctcaagggcactacgctggaggaagtgtatgcatcagtggctaaagtggcggat
tactggcttgatgttctatacagcaaggctgccaacatgccagactccgagctgtttgaa
ctgatctctgaaaaccgatcgatgtcccgtaagctagaggactacggagagcagaagtcc
acctcgatcagcactgccaagagactggccgagttccttggggatcagatggtgaaagat
gctggtctcagctgtcgatatgtcatctccaagaagcctgaagggtcccccgtcactgag
cgagctatcccgctggcaatctttcaagctgagcctagcgttaggaagcattatcttcgt
aagtggctgaagagcccttccttgcaggagtttgagatcagatcaattcttgactgggat
tactacattgaaagacttggtagtgccatacagaaaatcatcaccatcccagcagctctg
cagcaggttaagaatccagtgcctcgagtacgccaccctgactggctgcataagaaactg
ctggagaaaaacgatgtgtacaagcagaagaaaatcaatgagctgttcagcagtgaggga
aagagacagatcacttcaaatcagcctgtggaaagcagccagcagtcggagattgctgac
atggaggacttgggcgctcccaagcggctccagccatcaattccaatcgccagcaaacga
aagagagttgtggcagggggacagagccaggaggagtcccaagatctggagctcacccag
tcatggagagagattctagggccacctcctcccattggaagtacaaaggatgagcgttta
gtttggctgagataccacaagaagaaatgggaactgcaagccagacagcggaaggagcgc
aggaagaagcgacggcttgaagatggggaggcagtcaccggtgggggagggatcattcgg
gacacactaaccactggccttggcagcttcttacgtagaactgcaaggactattttggat
atgccctggcagttagtgcagattgcagagacaaaccagcctggtctgtttaagctatgg
gcagttatcggcagtgatttacactcaatcaaactgaatatccctcgggtcttccatgta
aaccagagaatacccaagttggaagaaagcacggcttacaggaaggtgaacaggatcctc
cctcgctccaacgttgtctataacctgtatgaatactctgtgccagaggacatgtaccaa
gaacatatcaatgagatcaacgcagacctctctgcccctgacatagagggagtgtatgaa
actcagatacctctgctgtttcgtgccttggtgcagctaggctgcgtatgtatggtgaat
aaacaattaattcgccatcttgccgggagggaggctgagacctttgaactggagcacctg
gaaatgagatctctggcacagtttgcttacctggagccaggaagcattcggcacatttac
ctttaccacaactcgcaggggaataaagctctgtttggactctttatcccttcccagcga
aaggtgtctgtgtttgttgttgatacggttcgaagcaaccagatgccaaacttgaacaac
atgtattctgtggagcgcacggccatgctggagaaggtggatgaagagctgcttccacct
gataaacacagctttgagattcgagccgaaacagacctgaaaactgtttacagggccatt
cagagactgctgttaaactacaaggatgaacgaaggggacctaccctgatagcaatccag
tctaattgggacctaaagaggctgtctaatggaatgcctgtctttgaagagtttccctta
gttcctgtccatattattgatgagatcagctataatgtcctggattggcaacgccacgga
gcccggcgaatgattaagcactaccttaacctggacagctgcctgacccaagcgtttgaa
atggcaagatattatcacattccggttgggaatctcccggaagatatctcgacatttggt
tcagatctgttcttttcccggcacctgcgacgccacaaccacttgctgtggctgtctcca
aactctcgaccagatctgggtggcaaagaaatggacgataaccgactggtgatggagttt
gatgaaaaagtgtcggtggaaatcaacaaccctggttgctactcaacagtttgtgtggaa
ttggatatccaaagtttggctgtgaataccatcctacagtcccaccacattaatgacatg
gagggagcgtcaagtgtggggatcagctttgacgtcattcagcaagcatctctcgaagac
atggtgactggaaaccagacaaatacactggccagttatgatgagacagccctgtgttcc
aatacatttaggattctgaagagtatggtggttggttgggtgaaggagatcactcagtac
cacaatgtctatgctgataatcaggtgatgcatttttaccgctggttgagatccccttcg
tcactgctgtatgacccagcgctgcaccggatgctgcataacatgatgaaaaagctgttc
cttcagttagtagcagaattcaaacgtttaggctcctccatagtttatggaaacttcaat
cgtatcattctgtgtacaaagaagcgaagaattgaggatgcgataggctatgttgaatac
atcacaaacagtattcatactcgtgagattttccactccttaaccatctccttttcccgg
tgttgggaattcattttgtggatggatccagcaaattatggaggaattaaagggaaactc
ccttctagtattatgtatggagaaacggagaagaagaaaggggaagagggaagtgaggat
gaagaggaggaggcagttgaccccgatgaggacagtgctggggaagatgacgttgaggag
ctgctggagaataactggaatattatgcagttcctgccccaggaggcatcctgtcaaagc
tatttcctgatgattgtatctgcttatattgtagcggtataccatagtatgaaagaggaa
atgaggcgaaatgccccaggaagtactcctgtcaagaggagaggagcatcaagccaagta
tcccaggaatctgaaggagatgcaggagctctgccaggtatgatcacattctctcaagat
tatgtgtccaacgagctcacccagaacttcttcaccatcactcagaagattcagaagaag
gtgactggcactcgccgtgccacggaaccctctgagatgttccctgttttaccggggtct
tacctgccacttaacaaccctgcactggaatttatcaaatatgtctgcagggccctatcc
ctggacatgaacataaccaatcaggttaacaaactcaaacgggatctcctacgcctagtt
gatgttggtgagttttcagaagaagcccagttcaaggatccctgccagtcctacatactg
ccagaagtcatctgcaggcactgtaacttctgcagagatttggacctttgcaaggacccc
tccatggcacaggatgggacggtgctgcccagttggctctgtactaactgccaggcagaa
tatgactctggttctattgagatggcacttgttgaagcagtacagaagaagcttatggcc
tacaccttgcaagacttggtttgcacaaaatgtaaagggatcaaagaagccaatatgcca
atttactgtagctgtgctggagatttcgatctgaccatctctaaaaagggattttctgag
cagatgaaggttttcagaaagattgctcatcactacggtatgcctttcctcttggagacc
attgagtggcttgtacagatgaatccacctatctgtacataa
DBGET
integrated database retrieval system
