KEGG   Latimeria chalumnae (coelacanth): 102356715
Entry
102356715         CDS       T02913                                 
Symbol
CACNA1S
Name
(RefSeq) calcium voltage-gated channel subunit alpha1 S
  KO
K04857  voltage-dependent calcium channel L type alpha-1S
Organism
lcm  Latimeria chalumnae (coelacanth)
Pathway
lcm04010  MAPK signaling pathway
lcm04020  Calcium signaling pathway
lcm04260  Cardiac muscle contraction
lcm04261  Adrenergic signaling in cardiomyocytes
lcm04270  Vascular smooth muscle contraction
lcm04912  GnRH signaling pathway
Brite
KEGG Orthology (KO) [BR:lcm00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102356715 (CACNA1S)
   04020 Calcium signaling pathway
    102356715 (CACNA1S)
 09150 Organismal Systems
  09152 Endocrine system
   04912 GnRH signaling pathway
    102356715 (CACNA1S)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    102356715 (CACNA1S)
   04261 Adrenergic signaling in cardiomyocytes
    102356715 (CACNA1S)
   04270 Vascular smooth muscle contraction
    102356715 (CACNA1S)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:lcm04040]
    102356715 (CACNA1S)
Ion channels [BR:lcm04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   102356715 (CACNA1S)
SSDB
Motif
Pfam: Ion_trans GPHH Ca_chan_IQ CAC1F_C PKD_channel DUF2670
Other DBs
NCBI-GeneID: 102356715
NCBI-ProteinID: XP_005988501
Ensembl: ENSLACG00000017615
LinkDB
Position
Un
AA seq 1858 aa
MEPNAVPDTNSLQRKKQKEKAKKQMNAGSPRPARALFCLNLQNPIRKACISIVEWKPFEI
IILLTIFANCIALAVFLPMPEDDTNNTNSSLEKVEYIFLIIFTIEATLKIIAYGFLFHPD
AYLRNGWNILDFIIVFVGLCTVALEQISRIQGGTAPVGGKGAGFDVKALRAFRVLRPLRL
VSGVPSLQVVLNSIIKAMVPLLHIALLVLFMIIIYAIIGLELFMGKMHKTCYYVGSDVVA
TVENEKAAPCASAGHGRHCTLNMTECRTGWPGPNNGITHFDNFGFAMLTVYQCITMEGWT
DVLYWVNDAIGNEWPWIYFVSLILLGSFFVLNLVLGVLSGEFTKEREKAKSRGAFQKLRE
RQQLEEDLKGYLDWITHAEVMDPDQERGEGILQSDENGSETDSLYEIEGMNKCILFFRRW
RRWNRLFRRKCRAVVKSKFFYWLVILLVFLNTLTIASEHHNQSDWLTSVQDTANKVLLAL
FTAEMLLKMYALGFQPYFMSLFNRFDCFVVCGGILETILVEANIMSPLGISVLRCIRLLR
IFKITRYWTSLSNLVASLLNSVRSIASLLLLLFLFMIIFSLLGMQVFGGKYNFDDLEVRR
STFDNFPQALISVFQILTGEDWNSVMYNGIIAYGGPSFPGVLVCIYFIILFVCGNYILLN
VFLAIAVDNLADAESLTSAQKAKAEEKKRRKMARSSHPEKSEEEKQLLLKKLEQKAKGEG
IPTTAKLKIDEFESNVNEIKDPYPSADFPGDDEEEEPEIPLSPRPRPLAELQLKEKAVPM
PEASAFFIFSPTNKIRVLCHRIVNATTFTNFILLFILLSSISLAAEDPIRPDSFRNQILN
YFDIVFTVIFTTEIVLKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAISVV
KILRVLRVLRPLRAINRAKGLKHVVQCVFVAIKTIGNIVIVTTLLQFMFACIGVQLFKGK
FYSCTDVSKMTEEECKGYYVMYKEGDVHQLELRERKWVNSDFNFDSVLSAMMALFTVSTF
EGWPQLLYKAIDSHAENMGPIYNYRIEIAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGE
QEYKNCELDKNQRQCVQYALKARPLRRYIPKNPYQYQIWYVVTSSYFEYLMFALILLNTI
CLGMQHYGQSDEISYLSDMLNVVFTGLFTLEMVLKLLAFKVKGYFSDPWNVFDFLIVIGS
IIDVVLSEIDDSEDTSRISITFFRLFRVMRLVKLLSRGEGVRTLLWTFIKSFQALPYVAL
LIVMLFFIYAVIGMQVFGKVAMVDGTQINRNNNFQTFPQAVLLLFRCATGEAWQEILLGC
SYGKLCDPESDYNPGEEYTCGSSFAYFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWS
ILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCPHRVACKRLVSMN
MPLNSDGTVTFNATLFALVRTALKVKTEGNFEQSNEELRAIIKKIWKRTSMKLLDQVIPP
IGDDEVTVGKFYATFLIQDHFRKFMKRQEEYYGYRPKKSAVEIQAGLRSIEEEAAPEIHR
TISGDLTAEEELERAMEEEIYRRSGGLFGNHVDHFPMETSSPLQPHVTSQRPLQFSESRG
EDLESPVFLPNEVEFFPSGSSANVNNANNNAIARMYLEDELNKEIPQACDSTERGLSIKR
RSRPLSMPERKLSFHLDHLKRRLTQQTDDTTIEMTELRGFAQQEPEVIVDPGSEQDGRVS
QSSDPERLRASGQHQQRETVLRTPATDKLIQKVLVSGGLGCLASDPSLVAVTKQEMASAC
HMAIDDLESAAVGLLHDWKSQAGLSHPPQHTPSETSLCNVHELEDTSSDGEVTSVSTL
NT seq 5577 nt   +upstreamnt  +downstreamnt
atggagcccaacgctgttcccgacacaaattcgcttcagcgaaagaagcaaaaggaaaag
gccaaaaaacagatgaatgctggatctcccagaccagccagggctttattctgtttgaat
ttacaaaaccccatccggaaagcctgcatcagcattgtggaatggaaaccctttgagatt
atcatcttgctgaccatcttcgccaactgcatagccctggcagtgttcctccctatgcca
gaggatgataccaacaacaccaactctagtctggaaaaagtcgagtatatcttcctaata
atcttcacaatagaggcaaccttaaagatcatagcgtatggattcctgtttcacccggac
gcatacctccggaatggctggaatatattggacttcataatagtatttgttgggctctgc
acagtggctctggaacagatcagccggattcaaggcgggaccgctccggtgggtggcaaa
ggagcagggtttgatgtgaaggcattgagagctttccgagtcctgaggcctctccgtctt
gtgtcaggagtgccaagcttgcaggttgtgttgaattccattatcaaagccatggttcct
ctgctgcacattgcactgctggtgctcttcatgatcatcatctatgccatcatcgggctg
gagctattcatgggcaagatgcacaaaacctgctattacgttggatcagacgtcgtcgcc
actgtggagaacgagaaagcggcaccctgcgccagtgccggtcacggccgccattgcacc
ttaaacatgacagagtgcaggactggttggcctggaccaaacaatggcattacccacttt
gataacttcggattcgccatgctgacagtgtaccagtgcatcactatggagggatggacc
gatgtcctttattgggtcaatgatgcgattggtaatgaatggccctggatctattttgta
agcctgatcttgctgggctctttcttcgtcttgaacctggtgctgggtgtcctcagcggg
gagtttacgaaggagcgagagaaagcaaaatctcggggtgcatttcagaagctgcgtgag
agacagcagctagaggaggatttgaagggctatttggactggatcactcatgctgaggtt
atggacccagaccaggaaagaggagaagggattttgcagtctgacgagaacggctctgaa
acggacagtctgtacgagattgaggggatgaacaagtgcattctcttcttccggcgttgg
cgccgctggaaccgcctgttccgcaggaagtgccgggctgtggtgaagtccaagttcttc
tactggcttgtgatcctgttggtgttcctcaacaccttgaccattgcgtcggaacaccac
aaccaatccgactggctcaccagcgtgcaagacacagcaaacaaagttctcctggccttg
ttcacggctgagatgttactgaagatgtacgccctgggcttccaaccctacttcatgtct
ctctttaaccgctttgactgctttgtggtatgtgggggcattctggagaccatcctcgtg
gaagcgaacatcatgtctcccctcggcatctctgtgctgaggtgtattcgcctcctgagg
atctttaaaatcaccagatattggacttccctgagtaatctggtggcctctctgttgaac
tcagtccgctccatcgcctccttactgctcctgctctttctcttcatgatcatcttctcc
ctgctggggatgcaggtcttcggagggaaatacaactttgatgacttggaggtcaggagg
agtacctttgataactttccccaggcgctcatcagcgtcttccagatcctgacgggagag
gactggaactcggtgatgtacaatgggatcattgcatatggagggccctccttccccggt
gtcctcgtctgcatttacttcattattctgtttgtctgtgggaactatatcctactgaat
gttttcctggccatcgccgtagataatctcgctgatgcggaaagcctaacctcagctcag
aaagccaaggcagaggagaagaagagaagaaaaatggccaggagtagtcacccagagaaa
tcagaggaggagaagcagctgttgttgaagaaactggagcagaaagccaagggcgaagga
attcccaccactgctaagctcaaaatagatgagtttgaatcaaatgtgaatgaaatcaag
gacccctatccttctgcagacttcccaggtgatgacgaggaggaggaacccgaaatcccc
ctaagtccccgcccacgtccactggcagagctacagctcaaagagaaggcagtgcctatg
cccgaggctagcgctttcttcatctttagtccaacaaacaagatccgagtgttgtgtcac
agaattgtcaatgccaccactttcaccaacttcatcctgctcttcatcctgctcagtagc
atctcattggccgctgaggaccccattcggcctgattctttcagaaaccagatccttaat
tattttgacattgtcttcacggtcatctttactacagaaatcgtcttaaagatgacagca
tatggggctttcctgcacaagggttccttttgccgtaactacttcaacattcttgacttg
ctggtggtcagtgtgtctctaatatcctttggaatacagtccagtgctatctctgttgtg
aagattttgagggtgttgagggtcctgagaccactaagagccattaacagagcaaagggg
ttgaagcacgtggttcagtgtgtctttgtagccatcaaaacgatagggaacattgtgatt
gtcaccactctactacagttcatgtttgcctgcatcggagttcagctgttcaaggggaaa
ttctacagctgcacagatgtctctaagatgacagaagaagaatgcaaggggtactatgta
atgtacaaggagggggatgtacaccagttggagctgcgggagaggaagtgggtgaacagc
gattttaatttcgatagtgtcctctcggccatgatggcactcttcactgtttccaccttt
gagggctggcctcagctcctgtacaaagctattgactcccacgcagagaacatgggtccc
atttacaactatcgcatcgagatcgccatcttcttcatcatctacatcatcctcatcgcc
ttcttcatgatgaacatctttgtggggttcgttattgtcaccttccaggagcagggtgag
caggagtataagaactgtgagctggacaagaaccagcgccagtgcgtccagtatgcgcta
aaagctcggccgctgaggcgctacatcccgaagaacccttatcaatatcagatctggtat
gtggtaacgtcatcctactttgagtatctcatgttcgccttgatccttctgaataccatc
tgtcttggtatgcagcactatgggcaatctgatgagatcagctacctctctgacatgtta
aatgtggtcttcactgggctctttactctggaaatggttctcaaactgctcgcctttaaa
gtaaaaggttacttcagtgacccctggaacgtgtttgatttcctcattgtgattggcagc
atcattgatgtcgttctcagtgagattgatgattctgaggacacgtcccgcatttctatc
accttcttccgtctgttccgtgtgatgaggctggtgaaactgctgagccgaggggaagga
gttcggacccttctgtggacttttatcaagtccttccaggctctgccgtatgtagctctg
ctgattgtcatgctgttctttatttatgctgtcatcggcatgcaggtgtttggcaaagtt
gctatggtggatgggacccaaatcaaccggaacaacaatttccaaacgttccctcaggcc
gtgttgctgctgtttaggtgtgcaactggagaggcctggcaggagatcttactgggctgc
tcctatgggaagctctgtgaccccgaatcagactacaacccaggggaagagtacacctgc
ggatccagcttcgcctatttctacttcatcagcttctatatgctctgtgcattcctgata
attaacctgtttgtagctgtcatcatggacaactttgactacttgacccgggattggtct
attttgggtccccatcacctggatgagtttaaacgaatctgggcagagtatgacccagaa
gccaagggaagaattaaacacctggatgtggtgacactgttgagacgcattcagccacca
cttggattcggtaaattctgtccccaccgcgtggcctgtaagaggctggtaagcatgaac
atgcctttaaatagtgacggcacggtcaccttcaatgccaccctcttcgcccttgttaga
acagccctcaaagttaaaactgaaggtaattttgagcaatccaatgaagaactgagggcc
attattaagaagatttggaaaaggaccagtatgaaactacttgaccaggttattcctcca
attggagatgacgaggtgaccgtgggtaagttctatgccaccttcctcatccaggatcac
tttaggaagttcatgaagcgtcaggaggagtactatggttatcgaccaaagaagagtgct
gttgagatccaggctggtttgaggagcattgaagaggaagcagccccagagatccatcgt
accatttctggggacctaactgctgaggaggagctggagagagcaatggaggaggaaata
tacaggcggtcaggtggtttgtttggtaaccatgtcgaccatttccccatggagacgagc
agccccttgcagccccacgtgacaagccagcgccccctgcagttctccgaatccagagga
gaagatttggagtcccctgtattcttaccaaatgaggttgaattcttcccttcaggctcc
agtgctaacgtgaacaatgccaacaataatgccatagccaggatgtacttagaagatgag
ctaaacaaagaaattccgcaggcatgtgattccactgagagaggcttgtccatcaagaga
cgatcacgtcccctttccatgccagaaaggaaactctcatttcacttggaccacttgaag
aggcgactgacccaacagacagatgacacaacaatagaaatgacagagctacgtggcttt
gcacagcaggagccagaggtgattgttgacccgggaagcgaacaagacggtagagtgtca
cagagttcagatcccgagaggctccgtgccagcgggcagcaccagcagagggagacagtc
ttacgcacgccggccacagacaaactcatacagaaggttttggtttcaggaggtcttgga
tgcttagccagtgatccatccttggttgctgtgacaaagcaggaaatggccagtgcctgc
cacatggctatagatgacctggagagtgcagctgttgggctactacatgactggaagagc
caagctgggctttcccatcctccgcagcataccccctctgaaacatccttgtgcaatgtc
catgagcttgaagataccagctctgatggagaggtcacctcagtcagcacattgtag

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