Latimeria chalumnae (coelacanth): 102365542 Help Entry 102365542         CDS       T02913                                  Symbol PLCB3 Name (RefSeq) phospholipase C beta 3   KO K05858   phosphatidylinositol phospholipase C, beta [EC:3.1.4.11] Organism lcm  Latimeria chalumnae (coelacanth) Pathway lcm00562   Inositol phosphate metabolism lcm01100   Metabolic pathways lcm04020   Calcium signaling pathway lcm04070   Phosphatidylinositol signaling system lcm04081   Hormone signaling lcm04082   Neuroactive ligand signaling lcm04261   Adrenergic signaling in cardiomyocytes lcm04270   Vascular smooth muscle contraction lcm04310   Wnt signaling pathway lcm04371   Apelin signaling pathway lcm04540   Gap junction lcm04621   NOD-like receptor signaling pathway lcm04912   GnRH signaling pathway lcm04916   Melanogenesis Module lcm_M00130   Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 Brite KEGG Orthology (KO) [BR:lcm00001]  09100 Metabolism   09101 Carbohydrate metabolism    00562 Inositol phosphate metabolism     102365542 (PLCB3)  09130 Environmental Information Processing   09132 Signal transduction    04310 Wnt signaling pathway     102365542 (PLCB3)    04371 Apelin signaling pathway     102365542 (PLCB3)    04020 Calcium signaling pathway     102365542 (PLCB3)    04070 Phosphatidylinositol signaling system     102365542 (PLCB3)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     102365542 (PLCB3)    04081 Hormone signaling     102365542 (PLCB3)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04540 Gap junction     102365542 (PLCB3)  09150 Organismal Systems   09151 Immune system    04621 NOD-like receptor signaling pathway     102365542 (PLCB3)   09152 Endocrine system    04912 GnRH signaling pathway     102365542 (PLCB3)    04916 Melanogenesis     102365542 (PLCB3)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     102365542 (PLCB3)    04270 Vascular smooth muscle contraction     102365542 (PLCB3)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:lcm04131]     102365542 (PLCB3) Enzymes [BR:lcm01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.4  Phosphoric-diester hydrolases     3.1.4.11  phosphoinositide phospholipase C      102365542 (PLCB3) Membrane trafficking [BR:lcm04131]  Exocytosis   Calcium ion-dependent exocytosis    Phospholipases     102365542 (PLCB3)  Endocytosis   Macropinocytosis    Phospholipase C     102365542 (PLCB3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PI-PLC-X PLC-beta_C PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like Motif Other DBs NCBI-GeneID:  102365542 NCBI-ProteinID:  XP_014354535 Ensembl:  ENSLACG00000013109 LinkDB All DBs Position Un AA seq 1253 aa AA seqDB search MAGARPGVHALQLKPVAVHETLKRGSKFIKWDEEPANRNLVTLRVDPEGFFLYWTGTSLE VDVLDISFIRDTRTGKYAKIPKDPKMREILGFENSGSPQERKPEDKLVTVIHGPDVVNIT FLNFMAVQEDTAKIWTEELFKLATNILAQNVSRNTFLQKVYIRLKLQVNQDNRIPVKNII NMFSMEKKRVESALEMCGLSFKKNEAIKPDEFTLEIFQQFLRKLCPRQDIDNLVAELGAG IKPYITLEQLRGFVNHKQRDTRLNEILYPPLRDYQIRQLIEKYEPNKSFAENDRMSLDGF CQYLSGEENSIIPSEILDVSDDMTQPLSSYFINSSHNTYLTAGQLTGVSSVEVYRQVLLT GCRCIELDCWPGRLPEEEPFITHGFTMTTEIPFKEVIEAIAESAFKTSPYPVILSFENHV ASSKQQAKMAEYCRTIFGDALLIDPLEKYPLVPGQPLPSPQELMGKILIKNKKRHHPKVL EGSVKRRLVEQSSFSETFSLLEQSSPSLGSPLHDPTELTSNGEERLLEKAQKDMEPRKSF DREAESDEDEEDDQQELKKPTTDEGTASSEVNATEEMSNLVNYIEPVKFKSFDVANKRNK YFEMSSFVETKGLEQLTKSPMDFLAYNKKQLSRIYPKGTRVDSSNYMPQVFWNVGCQMVA LNFQTLDLPMQLNMGVFDYNGRSGYILKPEFMRRMDKQFDPFTESIVDGIVANKLTVKII SGQFLSDRRVGIYVEVDVFGLPVDTKRKYKTKTSQGNSMNPVWDDEAFVFPKIVLPTLAS IRIAVFEEGGKFIGHRILPVSAIRPGYHYISLKNESNQSLMLPALLVYTEASDYIPDAHQ EYADMLTDPIKHMNKRTQQLQVLMAENGTDLENIEKLDDDPKPAQKSSPQIVPPLQKSPA PTELPVSNFGIQVQREDLIASVLADVQPQSVEDLKLQKACVKLQKKHYQELKELKKKHMK KISSLNKEQRSRINEFNIESVRRRSQVEKSLKRSNKKDPNRSSEDIKKELSALEAEVSQK NVELKEWQMQELLEMREKQYKAEKEKKCEHLKQELQKLKEVAMDCQASQLKRLKDQNEKE KKELQKILDRKRHNSITEIKSREKQKGSMVVLAEINTRHIKESVSSIRQLEAAQKKRHER LSLKHGEILQQIEEEELRLQATLEKQCEVEFQTLNQEIRRFLQEEMDGKTEGSNCNNGHF NTNSPVLGTSSAHSTPSSRDKLGRLGKSSFTEDGSVVSGPSSLLISEGDSTDL NT seq 3762 nt NT seq  +upstreamnt  +downstreamnt atggccggggcgcgtccgggagtccacgctctccaactcaagccggtggcggtgcacgaa accctcaagcggggcagcaagttcatcaaatgggacgaggaacctgcgaatcggaacttg gtgacccttcgtgtggacccggaaggcttcttcctctactggaccggaaccagcttggaa gttgacgttctggatatcagcttcatccgagacaccaggacagggaagtatgcgaaaatc cccaaggatccaaagatgcgggagattctggggtttgagaactcggggtctcctcaagaa agaaaaccagaagataaactggtgacggtgatacatgggccagatgtggttaacatcacc ttcctcaacttcatggctgttcaagaagacactgcgaagatttggacagaagagctgttt aaactcgccacaaacatcctggctcagaatgtgtctcgcaacaccttcctacagaaagtt tacattcgtctgaaactgcaggtcaatcaggacaacaggattcccgtcaaaaatattatt aacatgttttcaatggaaaagaagagggtggaatctgccctggagatgtgcggactgagc ttcaaaaagaatgaagccattaagccggatgagttcacgttggaaattttccagcagttt cttcgtaagctttgcccacggcaggacatcgacaaccttgtagcagaactgggggccgga attaaaccttacatcaccttagaacagctgcgggggttcgttaaccacaagcagcgggac acccgtctgaacgagatcctgtaccccccgctgagggactatcagatccgccaactcatc gagaagtatgagcccaacaagagttttgcagagaacgataggatgtcactggatggtttc tgccagtatctgagtggagaggagaatagcatcattccctccgagatcctggatgtgagt gatgacatgacacagccgctcagcagttactttataaactcctcccacaacacctacctc acagctggacagctcactggggtttcctcggtggaggtgtaccgtcaggttctgctcact ggttgccgctgtatcgagctggattgctggcccggtcggctgccagaggaagagcccttc atcacccacggtttcaccatgacgacggagattccatttaaggaggtgattgaagccatt gcagaaagtgcattcaagacgtccccataccctgtcatcctctccttcgagaaccacgtg gcatcctccaagcagcaggcaaagatggcggaatattgccggacaatctttggagatgca ctcctcatcgacccgctggagaaataccctctggttccagggcagccactgccaagtccg caagagctgatggggaagatcctgattaagaataagaagagacaccaccccaaagtgttg gaggggagcgtgaaacgccgtctggttgaacagagctcattcagcgaaacctttagcctg ctggaacaatcctcccccagtctcggatctcccctgcacgatccgactgagctgacgtcc aacggagaggagagactgctggaaaaagcgcagaaggacatggagcccaggaaatcgttc gatcgggaggctgagagtgatgaagatgaggaagatgaccagcaagagctcaaaaagccc acaacagacgagggaacagccagcagtgaggtgaacgcaaccgaagagatgtccaacctg gtgaactacatcgaacctgtgaagtttaagtcgtttgacgtagccaataagagaaataag tactttgagatgtcgtcctttgtagagacaaaaggcctggagcagctgaccaagagcccc atggattttttagcgtacaacaaaaagcagctgagtcggatctatccgaagggaacgcgg gtcgattcctccaattacatgcctcaggtcttctggaacgtcggatgtcagatggtggcc ctgaacttccagacgctggatctgccaatgcaactgaacatgggagtgtttgattataac ggacggagcggatacatcctgaagccagagttcatgaggcggatggataagcagtttgac ccctttactgaaagcattgtggacggtatcgtggctaacaagctcacagtgaagataatc tcaggtcagttcctctctgatcggagggttgggatttatgtggaggtggacgtgttcgga cttcctgtcgataccaagcggaaatacaagaccaaaacctcccaggggaattccatgaac cctgtatgggatgacgaggctttcgtctttccgaagattgtcttacccacgctggcaagc atcagaattgctgtctttgaggagggaggcaagttcattggtcatcggatcctgccagtg tccgctatccgaccgggttaccattatatcagtctgaagaatgagagtaaccagtcgctg atgcttccggctctgctggtttatacggaggcttcagattatattcctgacgcgcatcaa gaatatgccgacatgttgactgaccccatcaaacacatgaacaaaagaacccaacagctg caggtcttaatggcggagaacgggacagatttagagaacattgaaaagctggatgacgat cccaaaccagcgcagaagtcttcgccacagatcgtaccgccgttacagaaatccccggca ccaactgaacttccagtatcaaactttgggattcaagtgcaaagggaggatcttattgcc agcgtgttggcagatgtgcagccccagtcagtagaggacttgaaactgcagaaggcatgc gtcaaacttcagaagaagcactaccaggagctcaaggagctaaagaagaagcacatgaaa aagatctccagtctgaacaaggagcaaaggagccggatcaacgagttcaacatagagagt gtccggcggcgttcccaagtagagaagagtctcaaacgcagcaataagaaagatcccaac agatcatctgaagatataaagaaggaactgagcgctctggaagctgaggtatcccagaag aacgtggagttgaaagagtggcagatgcaggagttgttggagatgcgggagaagcaatac aaggcagagaaggaaaagaagtgtgaacacctgaagcaagagttgcagaagctgaaggag gtggcgatggactgtcaagcgtctcagctgaagagattaaaggaccagaatgaaaaggag aagaaggagttgcagaagatactggaccggaaacgccacaacagcatcacagagatcaaa tccagggagaagcagaaggggagcatggtggtgctggcggagataaacactcgacacatc aaagaatcggtgagctcaatacgccagctggaggcggctcagaagaagcggcacgaaagg ctgagtctgaagcacggagagattttgcagcagattgaggaggaggaactgcggctacaa gcaactctggagaagcaatgtgaggtggagtttcagacacttaatcaggagatcaggagg ttcctgcaggaggaaatggacgggaagacagaagggtcaaactgcaacaacgggcacttc aacaccaacagcccagtgctggggacctcttcggctcacagcaccccatcttcccgggac aaactgggccgtctggggaaaagcagcttcactgaagatgggagtgtggtttctggtccc agcagtctgctaatctcggagggggacagtacagacttgtga

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