Lacticaseibacillus casei 12A: LCA12A_0234
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Entry
LCA12A_0234 CDS
T03665
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
lcx
Lacticaseibacillus casei 12A
Pathway
lcx00300
Lysine biosynthesis
lcx00550
Peptidoglycan biosynthesis
lcx01100
Metabolic pathways
lcx01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
lcx00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
LCA12A_0234
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
LCA12A_0234
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
LCA12A_0234
Enzymes [BR:
lcx01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
LCA12A_0234
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
EKP96100
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Position
complement(2507817..2509205)
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AA seq
462 aa
AA seq
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MKMTLAEIARVVKAQPLSEADGSHVVTGLAFDSRKLKPGMLFVPLRGERDGHEFIPAAAT
AGAVATFVAADHLPVTTKLITLVVPDPLKAMQQLAQYYLLMKVNPKVVAITGSNGKTTTK
DMTAAILATQYHVVKTPDNYNNEIGVPMTILSMEPNTEVLVLEMGMDRPGQLHALSTLAE
PDVAVITMIGEAHIEFFKTRDKIADAKMEITDGLKDDGTFIFNGDEPLLQERAKKITQER
ETFGLHPENTIFAHSISGHRNHTEFTVEAWPDLTFSIPIMGEYNVVNALAALLVGRKFHV
KPEIMQKALAHFQVTANRTQWLIGDVGEQILSDVYNANPTAMKAVIHDFSEFTATGRHIA
VLGDMLELGEQSPALHAGLAEALDPKEVQVVYLYGSDMKALADALAAKYPADQLHYYPLD
DKEQMTRDLQNDVNHDDMVLLKASHGLHLETVLSALVAGGRA
NT seq
1389 nt
NT seq
+upstream
nt +downstream
nt
atgaagatgacattggcagagattgcgcgagttgtgaaagctcaaccgctctctgaagca
gacgggtcgcatgtggtgaccggactggcttttgattcacgcaaattgaagccgggtatg
ctgtttgtgccgttacgcggtgaacgtgatggtcacgaatttattccggcggctgctacg
gctggcgcagtggcgacatttgttgcagctgatcatttacctgtcaccaccaagctgatt
acgctggtggtgccggatccgttgaaagcgatgcaacaattggcacaatattatctgttg
atgaaagtgaatcccaaagtggtggcgatcaccggcagcaatggcaaaacgacaacgaag
gacatgaccgctgcgatcttggccacacaatatcacgtcgttaaaacccctgataactat
aataatgaaatcggcgtgccaatgactattctcagcatggaacccaataccgaagtcttg
gttcttgagatggggatggatcggccagggcaattacatgcactgtcaaccttagctgaa
ccggatgtggccgtgattacgatgatcggggaagcacatattgaatttttcaagacccgg
gataaaattgccgatgccaaaatggaaatcactgatggcctaaaggatgatggtacgttt
atttttaatggtgacgaaccattgttgcaggaacgggcgaagaagatcacgcaggagcgc
gaaacttttggcttgcatcctgaaaatacgatatttgcccattcaatcagcgggcatcgt
aaccacactgagttcacagttgaagcttggcctgatctgacgttctcgattccgattatg
ggtgaatataatgttgtcaatgcgttagcagccttgttagttggccgcaaattccatgtc
aaacccgaaatcatgcaaaaggcattggctcattttcaggtgacggctaaccggacacag
tggttgatcggggatgtgggtgaacagattctaagcgatgtttataacgccaacccgacc
gcgatgaaagccgtcattcatgattttagcgaatttacggcaactggccgtcacattgca
gtgctaggggacatgctggagcttggtgaacaaagtcccgcgttgcatgcaggtctggca
gaggcactcgatcctaaggaagtgcaggttgtttatctatacggtagcgatatgaaagca
cttgccgatgcattggcagcaaaatatccagccgatcagttgcactattatccgcttgat
gacaaggaacagatgacgcgcgacttacaaaacgatgttaaccatgacgatatggttttg
ttgaaagcgagtcacggattgcatctggaaaccgttttgtcagctttggtcgctggtggt
cgtgcttaa
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