Lactobacillus delbrueckii subsp. bulgaricus 2038: LBU_0287
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Entry
LBU_0287 CDS
T01957
Name
(GenBank) D-ala-d-ala adding enzyme
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
ldl
Lactobacillus delbrueckii subsp. bulgaricus 2038
Pathway
ldl00300
Lysine biosynthesis
ldl00550
Peptidoglycan biosynthesis
ldl01100
Metabolic pathways
ldl01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
ldl00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
LBU_0287
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
LBU_0287
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
LBU_0287
Enzymes [BR:
ldl01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
LBU_0287
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ADY84472
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All DBs
Position
296138..297505
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AA seq
455 aa
AA seq
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MKMQLAEIAQALNTSCEGDAETVITSVAFDSRKISQGALFVPIKGERDGHDFVGSAIEAG
ASATLWEAGNPNKPEGIAVLEVADTLKAMQDLARYYLQKVNPTVVSITGSNGKTTTKDMV
AAVLAKRFNVYKTQANFNNEIGVPMTILEMKPITEILVLEMGMDRAGQLHELSQLVRPDV
AVITMIGEAHIEFFGSRDKIADAKMEITDFLQEDGEFIYNGDEPLLAERAAKLPQDKSTF
GFADSDSIHASDLRSTMHHSFFKINGTDREFSIPMIGRHNVANAMAAILVGRHFGESDEE
IAAGLANFVPTANRMEWEKGDCGEDIMSDIYNSNPTAVKAVTASFGQVPVSEDGRRIAVL
ADMLELGSRSADLHKGLAACLDPDKINVLYLYGPEMNHLYQALLDKYGQQNLHYYPEDEM
SHLIDDLKSDIHSQDIVLLKGSHGMHLERVLDRLK
NT seq
1368 nt
NT seq
+upstream
nt +downstream
nt
atgaaaatgcagttggcagaaatcgcccaagccttaaataccagttgtgaaggggacgca
gaaacggtcattacctcagtggcctttgactcaagaaagatcagccagggcgccctcttt
gtcccgatcaagggggaaagagacggccacgattttgtgggttcagccattgaagccggc
gccagcgccactttgtgggaagctggcaacccaaacaagccggaaggcatcgcggtttta
gaagttgccgacaccttgaaggccatgcaggatctggcccgctactacctgcagaaggtc
aacccaaccgtggtcagcatcaccggctcaaacggcaagaccacgaccaaggacatggtg
gcggcggttttggccaagcgcttcaacgtttacaagacccaggccaacttcaacaatgaa
atcggcgtgccgatgaccattttggaaatgaagccgatcactgaaatcctggttttggaa
atggggatggaccgagctggccaactgcatgaactgagccagctggtccggccggatgtg
gcggtcatcaccatgatcggggaagcccatatcgaattcttcggcagccgggacaagatc
gccgacgccaagatggaaatcacggactttttgcaagaagacggcgaatttatctacaac
ggtgatgaacccctcctggcggaaagagccgcaaagcttccccaggacaagtccaccttc
ggtttcgcggactctgacagcattcatgccagtgacctccgcagcaccatgcaccattcc
ttcttcaagattaacgggactgaccgggaattctcaattccaatgatcggccgccacaat
gtggctaacgccatggccgctattctggttggccgccacttcggggaaagcgacgaggaa
atcgccgctggcctggccaacttcgtgccaacggccaaccggatggaatgggaaaagggt
gactgcggtgaagacatcatgagcgatatctacaactccaacccaacggcagttaaggcc
gtgactgcctcctttggccaggttccagtcagtgaagacggccgccggatcgcggttttg
gccgacatgctggaactgggcagccggtcagccgacctgcacaagggtctggctgcctgc
ctggacccggacaagatcaacgtcctttacctttacgggccggagatgaaccacctttac
caggccctgctggacaagtacggccagcagaatctgcactactacccagaagacgagatg
agccatttaatcgatgatttaaagagcgacatccacagccaggacatcgttttgctgaag
gggtcccacgggatgcacctggaacgagtcctcgacagactgaaatag
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