Leishmania donovani: LDBPK_100310
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Entry
LDBPK_100310 CDS
T02289
Name
(RefSeq) isocitrate dehydrogenase [NADP], mitochondrial precursor, putative
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
ldo
Leishmania donovani
Pathway
ldo00020
Citrate cycle (TCA cycle)
ldo00480
Glutathione metabolism
ldo01100
Metabolic pathways
ldo01110
Biosynthesis of secondary metabolites
ldo01200
Carbon metabolism
ldo01210
2-Oxocarboxylic acid metabolism
ldo01230
Biosynthesis of amino acids
ldo04146
Peroxisome
Module
ldo_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
ldo00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
LDBPK_100310
09106 Metabolism of other amino acids
00480 Glutathione metabolism
LDBPK_100310
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
LDBPK_100310
Enzymes [BR:
ldo01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
LDBPK_100310
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GFIT
Motif
Pfam:
Iso_dh
Motif
Other DBs
NCBI-GeneID:
13392208
NCBI-ProteinID:
XP_003858870
UniProt:
A0A3Q8IC24
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Position
10:118381..119688
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AA seq
435 aa
AA seq
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MFRRVSAASASSLVAARSFSSTNVYLDKRIKVKNEVVDMDGDEMTRIIWSFIKEKLILPY
VDVPINYFDLSVTNRDATNDKVTVEAAEAIKKCNVGIKCATITPDEARVKEFNLKKMWKS
PNGTIRNILGGTVFREPIIVSNIPRIVPQWHNPIVVGRHAFGDQYKATDAVLKPGKLQLV
HTPADGSAPTTLDVYDFKGEGVGLAMYNTKESIEGFAKSCFQYALMRKYPLVLTTKNTIL
KKYDGMFLQTFQRMYDEQYKADFEKAGITYNHRLIDDQVAQMIKGEGGFVWACKNYDGDV
QSDIVAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHYRQHQQGKETSTNSVASIYAW
TRGLAHRGKLDGNSDLVKFSETLERVVVKAIEDGHMTKDLALCVYGSSGVKREHYETTEQ
FLDSVDAALKKAMSA
NT seq
1308 nt
NT seq
+upstream
nt +downstream
nt
atgttccgccgtgtttcggctgcttcggcgagctcgctcgtcgccgcacgctccttctcc
agcaccaacgtctacctggacaagcgcatcaaggtaaagaatgaggtggtagacatggac
ggcgacgagatgacgcgcattatctggtcgttcatcaaggaaaagctgatcctgccctac
gtggatgtcccgatcaactactttgacctcagcgtgactaaccgtgacgcgacgaacgac
aaggtcacggttgaagccgccgaagcgatcaagaagtgcaacgttggcatcaagtgcgcc
accatcacccccgatgaggcccgcgtgaaggagttcaacctgaagaagatgtggaagagc
ccaaacggcaccatccggaacatccttggcggcacggtgttccgtgagccgatcatcgtc
tccaacatcccacgtatcgtccctcagtggcacaatcccatcgtggtcggccgccacgcc
ttcggcgaccagtacaaggcgacggatgctgttttgaagcccggcaagctgcagctcgtg
cacacacccgccgacggcagcgcgccgacaacgctggatgtatacgacttcaagggcgag
ggtgtcgggctggccatgtacaacacgaaggagagcattgagggctttgcgaagagctgc
ttccagtacgcgttgatgcgcaagtacccactggttttgacgacgaagaacaccatcctg
aagaagtacgatggcatgttcctgcagaccttccagcgcatgtatgacgagcagtacaag
gccgacttcgagaaggccggcatcacgtacaaccaccgcctcatcgatgaccaggtggcg
cagatgatcaagggcgagggcggcttcgtgtgggcgtgcaagaactacgatggcgacgtg
cagagcgacatcgtggcgcaaggcttcggctcgctgggcctcatgacctctgtgctgatg
tgcccggatggcaagacaatcgaggccgaggccgcccacggcacggtgacgcgtcactac
cgccagcatcagcagggcaaggagacgagcacgaactccgtcgcctccatctacgcctgg
acgcgcggtctcgcccatcgtggcaagcttgacggcaacagcgacctcgtcaagttctcg
gagacgctggagagggtggtcgtcaaggcgattgaggatggccacatgacgaaggacctg
gccctctgcgtctacggctccagcggcgtcaagcgtgaacattacgagacgacggagcag
ttcctcgacagcgtcgatgcagccctgaagaaggcgatgagcgcgtaa
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