Leishmania donovani: LDBPK_140020
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Entry
LDBPK_140020 CDS
T02289
Name
(RefSeq) phosphatidylinositol 3-kinase 2, putative
KO
K00922
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:
2.7.1.153
]
Organism
ldo
Leishmania donovani
Pathway
ldo00562
Inositol phosphate metabolism
ldo01100
Metabolic pathways
ldo04070
Phosphatidylinositol signaling system
ldo04081
Hormone signaling
ldo04620
Toll-like receptor signaling pathway
ldo05100
Bacterial invasion of epithelial cells
Brite
KEGG Orthology (KO) [BR:
ldo00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
LDBPK_140020
09130 Environmental Information Processing
09132 Signal transduction
04070 Phosphatidylinositol signaling system
LDBPK_140020
09133 Signaling molecules and interaction
04081 Hormone signaling
LDBPK_140020
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
LDBPK_140020
09160 Human Diseases
09171 Infectious disease: bacterial
05100 Bacterial invasion of epithelial cells
LDBPK_140020
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
ldo04131
]
LDBPK_140020
Enzymes [BR:
ldo01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.153 phosphatidylinositol-4,5-bisphosphate 3-kinase
LDBPK_140020
Membrane trafficking [BR:
ldo04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
LDBPK_140020
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI3_PI4_kinase
PI3Ka
PI3K_rbd
PI3K_C2
Motif
Other DBs
NCBI-GeneID:
13391077
NCBI-ProteinID:
XP_003859374
UniProt:
E9BBN7
LinkDB
All DBs
Position
14:4127..7270
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AA seq
1047 aa
AA seq
DB search
MSLRVRLRVPKQWDRFQVNIDEELQQEELSRTLTEREIDDFNRRNLHSVSELSDHLRLLV
FGSDECVTCSEDICAAVEYIVGPQRRWNSSCDEVCEFRRAISRAYLNEWKAFQSVHPSVP
ERLATRSLPQVFSVPPLQKAQMDLLMQMCPRNAETGDGSISMRLWYLDSAGSRCSTRRRF
PFDTAADDAIRLTMSSAREFASMREKTDDTPLIFVFRVKGRNEYIYGSQPLINYRYIRHC
VSKRAEIDLVVEPKEATLFAVPLFRPSYPSRTLASPSDADASKSSTSEICLWDLTSKLSI
RIVGGFEKLAISASRMKDENVRDSSSLYFAVLVEAYVGTWRCCEPQITGWQLCENAKNSH
SLAARVYWKDGGTVTFSIDLSNVPRELKLCFTLVASSTDRIVGARAATAEEVIAAVEENT
KKTDDQGHSVFFLGTAATQLFDYAAKMRMGMWRIYLWEGKTRANPIGLNSINPDSNACTF
EVEFPCFDKPVFFPSGRPPKRKEEDARRNFADREAALSSYLINNEVEQLRQLKRVLMYDP
LVHLSSDDKTILWKYREMLLGQPKAMAKVMSAVNWLMPFDVYEAHCLLRRWSPLAAFDAL
ELLDAHYADLAVREQAVEYIDKMSDYELRGCILQLVQVLKYEPYHYSALARFLLRRSLRS
NHIIGHYVFWYLAAEVKNLTICERHGLLLEELIKRSPHRLDYVRQVYVCNELLKCALRVQ
RAPKKDRVKCLRASLAKVRFPHRFTLALNPSVECCAVDIDECKVMESKKFPLWLAFRNHL
DQDEHFFIIFKSGDDLRQDLLTLQLLEFMDSLWKASGLDLHLIPYGCISTGEGVGMIEVV
LNSDTIANITRREGGAQAAFNVDPIINWLRQFNHDRGEAERCLWNFVLSVAGYTVATYVL
GIGDRHNDNIMLRQDGTLFHIDFGHFLGNFKTKFGIKRETAPFIFTPMYLYAMGGSSSPI
FKYFVDVACRAYNALRRHSSALMMLFMLMLSTGIPELQTLEDIEWLRTVLLLNRTDEEAS
EHYKGLINDALGNFRTLLNDYIHIMVH
NT seq
3144 nt
NT seq
+upstream
nt +downstream
nt
atgtcgttacgcgtacgactacgggtgcccaagcagtgggataggtttcaggtgaacatc
gacgaggaacttcagcaagaagagctctcaaggactctgacagagagggagatcgatgat
ttcaaccgacggaacctccacagcgtctcggagctcagtgatcatttgcgcttgctcgtc
tttgggagtgatgagtgtgttacctgctctgaggatatttgtgcagctgtcgagtatatt
gtgggtccgcagcgcagatggaacagtagctgcgatgaagtttgcgagtttcggcgcgca
atcagcagagcgtacctgaatgaatggaaggcttttcagtctgtccatccatcggtgcca
gagcgcctcgcgacacgcagcctgccgcaggtgttttctgtacctcctcttcaaaaggca
caaatggatcttctgatgcagatgtgcccgaggaatgcggagacgggagatggcagcatt
tcgatgcgtctatggtatttagatagtgcagggtccagatgctctacgaggcgaaggttt
ccattcgacactgccgccgatgacgccatccggctcacgatgagcagcgcacgggagttt
gcaagcatgagggaaaaaactgatgatacgccgctcatctttgtcttccgtgttaagggg
cgaaacgagtacatttacggttcgcagcctctgataaattatcgttacattcgtcactgt
gtgagcaagcgggctgagatagatttggttgtggagcctaaagaagcgacccttttcgca
gtaccactgtttcgcccgtcctacccgtctcggacccttgcaagtccttctgacgcagat
gcgtcgaagtccagtacctctgaaatctgtttgtgggacctgaccagcaagctctctatc
aggattgtcggcggttttgaaaagcttgccatctccgcgtcgcgcatgaaggatgaaaac
gtgcgcgactcttcgagcctgtactttgcagttcttgtggaggcgtatgttggcacctgg
cgttgctgcgaaccccaaatcactggctggcagctgtgcgagaatgcaaagaacagccac
agcttagctgcaagagtgtactggaaggacgggggaacggtgaccttcagcatcgatctg
tcgaatgtgccaagagagctaaagctgtgttttacgctggtggcttcctcgaccgacaga
atcgtcggtgctcgggcagccactgcagaggaggtgattgccgctgtggaagagaacacg
aagaaaaccgacgatcagggtcactcggtttttttcttgggtacggccgccacgcagctt
ttcgattacgctgcaaaaatgcggatgggtatgtggcgcatctatctatgggagggcaag
acccgcgcgaacccgattggcttgaactctatcaaccccgattccaacgcgtgcacgttc
gaggtggagttcccgtgtttcgacaagcctgtttttttccccagtggtcgacctccaaag
agaaaagaggaggatgctcgacgaaactttgctgaccgtgaggccgccctgagcagctat
ctgatcaacaacgaagtagaacaactgcgccagctgaagcgggtgctgatgtacgatccc
ctggtgcacctctcgagtgacgacaagactattctgtggaagtacagggagatgctccta
ggccaaccaaaggcaatggccaaggtgatgagtgcggtgaactggctgatgccgttcgat
gtgtacgaggcacactgccttttgcgccgatggtccccgctggctgcgttcgatgcgctg
gagctgcttgacgcgcattatgctgacttggcggttcgtgagcaggcggtggagtacatt
gataaaatgtcggactatgagctgcgcggttgtattctgcaactcgtgcaggtactcaag
tacgagccgtatcactactctgccttggcgcgttttctccttaggcggtcgcttcgctcg
aaccacataattggccactacgttttttggtatctagctgccgaagtcaagaatctgacc
atttgcgagcgacacggactccttttggaggaactgatcaagcgatctccgcaccggttg
gactacgtgcggcaagtgtacgtttgcaacgagctgctgaagtgtgcactgagggtgcaa
cgggcgccgaagaaagatcgtgtcaagtgtctgcgcgcgagtctcgctaaggtgcgattt
cctcaccgctttactctcgctctgaacccctcagtggagtgctgcgcggtcgatatcgat
gagtgcaaggtcatggagtcgaagaagttcccgctatggcttgcttttcgaaatcatctc
gatcaagacgagcactttttcatcatattcaagtctggcgacgacctcaggcaagacctg
cttactctgcagctgctggagttcatggacagcctgtggaaagcgtccggtctggacctt
cacctcatcccatacggttgcatctctaccggagaaggcgttggcatgatcgaagtggtg
ttgaacagtgacacgatcgccaacatcacgagacgcgagggtggggcacaggctgcgttc
aacgttgacccgatcataaattggttacgtcagttcaaccatgaccgaggtgaagcggag
cggtgtctgtggaatttcgtgcttagtgtcgccggctacacggtggccacctacgtcctg
ggcatcggtgacagacataatgataacatcatgctccgccaggatggcaccctctttcac
atcgattttggccactttctgggcaacttcaagacgaagttcggcatcaagcgtgagaca
gcgcctttcatttttactcccatgtacctgtatgcgatgggtgggtcaagtagcccgatc
tttaagtactttgtggacgtagcatgccgagcgtacaacgcgctgcggcggcacagcagc
gcacttatgatgctctttatgctgatgctctctacgggcataccggagctacaaaccctg
gaagatatcgagtggctgcgcacagtacttcttcttaaccgaaccgatgaggaagcctcc
gagcactacaaaggcctcatcaacgacgcactgggcaattttcgcacactgctgaacgac
tacatccatattatggtgcactga
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