Leishmania donovani: LDBPK_211670
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Entry
LDBPK_211670 CDS
T02289
Name
(RefSeq) 2-oxoisovalerate dehydrogenase alpha subunit, putative
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
ldo
Leishmania donovani
Pathway
ldo00280
Valine, leucine and isoleucine degradation
ldo00640
Propanoate metabolism
ldo00785
Lipoic acid metabolism
ldo01100
Metabolic pathways
ldo01110
Biosynthesis of secondary metabolites
ldo01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
ldo00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
LDBPK_211670
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
LDBPK_211670
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
LDBPK_211670
Enzymes [BR:
ldo01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
LDBPK_211670
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Motif
Pfam:
E1_dh
DUF4440
Motif
Other DBs
NCBI-GeneID:
13386457
NCBI-ProteinID:
XP_003860684
UniProt:
E9BFF3
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Position
21:complement(581390..582829)
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AA seq
479 aa
AA seq
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MFHISRAVRCNALATAIAGRTSLSDAIRQVQKVWNLDFKDGPVTTSTLTFNDEPDPAAPI
FHVLDLQGGVFVEEKADSGAAAATPSTVNEAGKTELQSAELGQVFRYHAKDETSVITREV
AERMMSAMLTHNTIDKIMLEAQRQGRISFYMTMFGEEAAVIGAAAGLASNDELFAQYREA
GILTYRGYTIPEFIAQCMGNCECDLKGRQMPIHYGSKRLNAQMVSSPLATQIPHGAGAGY
AFRLENQALERRLPTGTLLSTIPEARICATFFGEGAASEGDFHAGLNFASTVGSHTLFFV
RNNGYAISTPTHSQYMGDGILSRAVGYGMPAARVDGLDALAVYHTVRKARELILNNHRPV
LVEALTYRLSHHSTSDDSTAYRSRDEIEHFAETFSPIERFERFMAERGWWTPEQSTEVVE
RTRREVLSELRRQEKLPAWPVSTLCDDVFEHLTPELERQRAQLVEHYQAHRSIYDQEKL
NT seq
1440 nt
NT seq
+upstream
nt +downstream
nt
atgttccacatctctcgtgcagtgcgctgcaacgcactcgccaccgccatcgctggccgt
acctcgctaagtgatgcgatacgccaggtgcagaaggtgtggaaccttgacttcaaggat
ggaccggtgaccacgagcacgctgacgttcaatgacgagcctgacccggctgcgccgatc
ttccatgtgctcgatttgcaaggcggcgtctttgtggaggaaaaggcagacagcggagct
gctgcagcaacgccttcaaccgtcaatgaggctggcaaaactgagctgcagagcgccgag
cttgggcaggtatttcgctaccatgcaaaggatgagacgagcgtcatcactcgcgaggtg
gcggagcgcatgatgtcggcgatgctgacgcacaacaccatagacaagataatgctagag
gcgcagcggcaaggccgcatctccttctacatgacgatgtttggcgaggaggctgccgtg
atcggcgcggcggctgggctggccagcaacgacgagctcttcgcgcaatacagagaggcg
ggtattctgacgtaccgcggctacactatacccgagtttatcgcgcagtgcatgggcaac
tgtgagtgcgatttgaagggccgtcagatgcctatccactacggcagcaagcgtctgaat
gcgcagatggtcagctccccgctcgccacgcagatccctcacggcgccggcgccggctac
gcgtttcggctagaaaaccaggcgctggagaggaggctgccgactggcacgctgctgtcg
acgattccggaggcgcgcatctgtgccaccttcttcggcgagggagccgcgagcgagggc
gacttccacgctgggctgaacttcgctagcaccgtcggctcgcacaccctcttctttgtg
cgcaacaatggttacgccatctcgaccccgacccacagccagtacatgggcgacggcatc
ttgagccgtgcggtaggctacggcatgccggccgccagagtcgacggcctcgacgcgctg
gcggtttaccataccgtgcgcaaggcacgtgaactgatcctgaacaaccaccggcccgtc
ctggtggaggcactgacgtaccgcctctcgcaccactcaacctccgacgacagtaccgcg
taccgctcgcgggacgagatcgagcacttcgcagagacctttagccccatcgagcgcttt
gagcgcttcatggcagagcgtggctggtggacgcccgagcagtcgacggaggttgtcgag
aggacccgcagagaggtgcttagcgagctgcgtcggcaggagaagctgcctgcatggcca
gtatcgaccctgtgcgatgacgtctttgagcacctgacgccagagctggagcggcagagg
gcgcagctggtggagcactaccaggcgcaccggtctatctacgatcaggagaagctttag
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