Leishmania donovani: LDBPK_220930
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Entry
LDBPK_220930 CDS
T02289
Name
(RefSeq) dynein heavy chain, cytosolic, putative
KO
K10413
dynein cytoplasmic 1 heavy chain
Organism
ldo
Leishmania donovani
Pathway
ldo04145
Phagosome
ldo04814
Motor proteins
Brite
KEGG Orthology (KO) [BR:
ldo00001
]
09140 Cellular Processes
09141 Transport and catabolism
04145 Phagosome
LDBPK_220930
09142 Cell motility
04814 Motor proteins
LDBPK_220930
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
ldo03036
]
LDBPK_220930
09183 Protein families: signaling and cellular processes
04812 Cytoskeleton proteins [BR:
ldo04812
]
LDBPK_220930
04147 Exosome [BR:
ldo04147
]
LDBPK_220930
Chromosome and associated proteins [BR:
ldo03036
]
Eukaryotic type
Centromeric chromatin formation proteins
SAC (spindle assembly checkpoint) factors
Motor proteins
Dynein complex
LDBPK_220930
Cytoskeleton proteins [BR:
ldo04812
]
Eukaryotic cytoskeleton proteins
Microtubules
Tubulin-binding proteins
Dyneins
LDBPK_220930
Exosome [BR:
ldo04147
]
Exosomal proteins
Proteins found in most exosomes
LDBPK_220930
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AAA_6
DHC_N2
AAA_9
AAA_8
AAA_7
MT
AAA_5
DYN_lid
Dynein_heavy
AAA_lid_11
Dynein_C
AAA
AAA_22
AAA_16
nSTAND3
FtsK_SpoIIIE
AAA_25
AAA_30
ABC_tran
Sigma54_activat
Mg_chelatase
AAA_lid_1
Dynein_AAA_lid
NB-ARC
POT1PC
PhoH
Motif
Other DBs
NCBI-GeneID:
13389564
NCBI-ProteinID:
XP_003860841
UniProt:
E9BFW0
LinkDB
All DBs
Position
22:425157..442142
Genome browser
AA seq
5661 aa
AA seq
DB search
MFPFDDDVVQFIVLLTQHGTVEKVRAAIAQSADAMDFASPPASPEGVMHLAAGQRRNIGE
RGRGDDGETGVVSKTALLGAHVPFIAVCEIADDRAAADGSQIIATADPATFFRSVSCMED
ATPEEAVSLGATARGGTGARRSTGGGAGDDSFPSARHKAKALSCILLERRDPHGVGGGTT
GGGGARALSVRDLYIQSMDLQRPLDTLQSILRNIYDPMLRSHKTQSALRTHVQDLLSSIC
SMHNVLPEIDVTRYVHEDLLQLCDANPLLDVPQLIDRLGEVAKDPSFIRRVLQVRNRCKE
ALSMEPLLSGKLEEEELAKELQSTNSKTIGSPAVGPTSLPSGLSGAHSQPSASAAPGKGA
AAGIAYDGDGGDDSAQVVQERIVYWRCVHAWMEDVLRQLRGREWRLVHRLLAQRVETDYV
GEYVGYLKLVQEYITFLNTIPEKRLANVQDMKEFNDVADEIIVAATQPTRFAARLQLSLL
TSLVWQISSRWVSVMETQQVLRLDEDPDAAPVAAAGDANETQHRADVTAGVHADPFVPLQ
ILRIAIHSLRTLQARYVEHSTQLRHQIRVVRNPREHVEHPRVEALLARCLAVRDLIEEHL
LLMRQLGVVFSTKIRLQFAKAKRDAVTAMGAAAAQQQPGEEYALVMQDAFNECVRAVCGW
ADDAEDLQRSRKGSVGESAASSGSPHRGHKGCGNYLWRTSPTAVQRFNAAVQEYQHKRSQ
CDEQIALVVSQLLSNQQHAHNDCRSGMGGAGAAGVAGMAGAGAALKGPQVSANYADNHGL
RLFRTFKSFKMLPLERVQRVVHSYQDAVAEKLSAYVSYVQDCYVNVPLTKQEVSYNMARF
SVSALVAQIMWEQRLAEALTKSMMRFDYVSEHGWHQLLYLRNVEHYWRLNASLAEFIGVP
LDLLVCDELQLDSEVHGCAVALACLSLHYTEEASEWEQDEHLRIAQDLVATRDPGALAVA
RDRMLIGGAPRLYKTTARVRDIRSSRDIIQQRIESHMASWFEEVDRLIGGSGLDQQTLLL
SGPVLWAVNCGPFSAPHNTTGGAVANEADSAVMRLQPSGGAGAMTGGFTANANYFNTGGA
GSMPRASSFSPSSLALLRAQGRSASPSVRRASFLVPVGSGDSESLAPAAATAASWMVEVA
FPWSFPIIAEDLRYLESSHLTSTLLSDGSGEPAATSRSSNSAAVTTPSPRGRCTAVASGL
AFLRDALRGNELRSRLAHTLVELIHVYYVTVKGEDTSLVLLATDEYQEVNRLFQMGIALR
WSDEGLLSYVQQLSDTMQAFTTTVQQLRSKTELVYRKIRAFLVRAFHPEAILQRVKALRR
IVDTLALRCVHAHLWTRQIQPLLEQALLTQMKYLMHSWTEDFLSMRGDVRFLEKGAETDV
FRLTPLRVRMRVVYKEVRLESCCGAWRQHWIGELNRFFSWIDVLPRLYKEEETQADVVGV
SAALGSDMTSTAGRISLTPSHRDNSVPPAAAVTHGSNGTDGAGINAGIGGAGSNGHNAAS
GRTPDDGYQYLLLRLPSSALAEPLHAIEQCVQDAIDTENEWRRGQQFLSMDVALMQQRFG
RDLRRWSHALRLMHTVTSRIMDYTQPNKLLGGIVILAQEAQIELGRKLDQVSQYAHAKFK
DLLQGEQERAFSVITQERTKIDALDVISNAKDAAAFLSEAPRLKSELQKLDGEITLMGNG
EVSLQKLGHVFPENWMYAAALREEYTSLAELVDRKLKAVQVRRPFLIEEAKSAASALEVK
VAEVDARFHNVDSIAVSKEAPVLAKQLVSDIYEEAVAFSVEAKQVTAIQEALGESPHVFA
SLQKLLADVALVKDVWGHVVSAYVELNELGATPFFEMVPRRLHERLQQIDEETDAYQETM
HSYQLYQNLKQKLCRVLSYNRLMQDLRSDAMSPLERSMRHWTALQHKLRAPWVLASLTVA
NIWESDPGANAAVYSEVVETAQGERRIEVQLHNINNYWNMFEFSVVVYKKQVALIRGWDE
VFERLTEDLSTFGGMRASPYFVFPQLVSMVNDAEARLDRLRQVLEVLLEVQKRWVYLDGI
LSENAEVRAQLPHDTVKFDRTSRELLHILPRPRSSGNLPELHVSFFLEDEKLKATLERLL
SQLAAVQRALTSYLDTQRSRFPRFFFAGDDDLLEIMGNSKNPLFLNKHLKKMFTALAALQ
LDGNVKDATTRLRGFSSAEGEELSFQPGPISYGHRPIHEWLGEAEQGMVHTLREATLRAY
NELVSTKDASPYALLWSMDWVRQKPTQVLCLALQLLWTREQESLLTGAHGGSAGAADARR
TSRASSSKLSVLTSSMDDLLARLAGNVLGNAVAPSSRRQCEQLITIAVYQRDVSRTLAAR
KVASRNDFNWLSVLRLYVVPTHHQQQPGGKSMSSLSNIGLAHSTNVSELVLSEYRTAETL
ECRMADASVLHGFEYIGAYERLVQTPLTDKCYLTLMQALHTRLGGSPVGPAGTGKTETVK
ALGMQLGRHVLVFNCDDTFDYQAVSRIFLGLCQVGAWGCFDEFNRLEERILSALSLQIQV
IQQSLRARQREVQLNHRAVPLHSNVAIFITMNPGYAGRSKLPGNLKQLFRTVTMTIPDRE
TIAEVMLFAQGFATAEALSQKVVPLFRLCEEQFTRQAHYDFSLRALKSVLVAAGDRKRQV
AVASRGNHGSHNAAGGAGADAVQETERTLLLESIIATVAPKLVAQDAALFYPLLHDFFPG
CSLPALPMGELREAVECVCAESGLSTAAGWMEKVLQFYHTKMTRHGVMIVGPSGTGKTTA
WKVLMAAMVRLERALQMHAYVLSPKVLSKGELFGTLDVTTREWRDGVFTSILRKIIDAEE
QQQIPDDLELAGNDDTDHKVVAAPSMGVDNKKRVSLKRNLTCGGDASELRAQDLEARKEH
WIIFDGDVDPEWVENLNSVLDDNRLLTLPNGERLPLPRSVRIIFEVQDLLYATPATVSRC
GMLWFSEGVVPLSGVLAHTYYQLQEHPIVDARGRHLHWGTDHMIGVTGARSALYAECLVS
GEYGKVYHEFVLSSTRTSAEEVMAGSLPRHHGRTSSGDEGITALETPKRSSHLCKDATPR
NDKAAELDMGDTLYGTTGHGSHTIFTSTSGGGASTLRRSHPDAERIQELMVSSWAAAFEK
DGAVVRGLQLMKSAAFRGVCVMVPSDLQCIQSMVAFLVQGVWRTFETEQQNNGDVFSDAV
VKKIAMQVLSYAIFWGLASAMSLENRMKLAQQLGLRPTVDGVAQSMLEVEVCYRTGEWRL
IRNRVKEISLLAEQVGANDTVITTVDTCRHEDVLSAWLGAGRSAILCGPPGSGKTMSITA
VLSSLPEYEVVFLNFSSGTTVKTIVKALEQHCRVQDTARGLVMAPTSGKQLLLFCDEVNL
PALDRYGTQVVVQLLRQLIERNGFYRARDNTWITVEDVQVVGACNPPTDPGRVPLSARFL
RWAPVLLVDFPSPESLKTIYTTYCRAILAWNERLSGQVATHLAQAMVKMYRVSQAKFTPI
QQPHYLYSPRELSRWSRALYEGILTWDDTVRRQLDVSQLVRLAVHEGLRVFADRLVTAEE
RAWTGTAIVKAFREFFTDVDDHAFHQPLLYSTLLSRSYTDSPREELREYVQKKLAAFNEE
ESLGNLVIYDAMIDHVVRIDRVLRQPLGHLLIAGSSGVGKTALTKLVAWMRGFSTFTLML
HRGYDLDDFEHDLRGVLRRAGCKRERICFLFDESNILQPSFLEYMNALLASGEVPGLFDG
DEWSKLMQEVRDAVLASQSYYATSRGAGAGAVAAGRAGGGGEAGRDRDSSVLRGGGCKGL
DGNDNGDGVTGCRRASAVTGVGVAASAAADNLVDVHNEAELYHWFLTNVREYLHVVLTIN
PSSGEFTSRTVASPALVNRCTIDWFGDWDTATLQQVCQERICRLALLPACHGVFATEVEA
KEAVVESLCAIHVATQHINQALRVRHANQGTFVTPRHFTDCVSHFVAIFQEKKKVSSDAL
VHLRSGLKKLELTAQEVSAQRATLQDNEAEIEASSRRAQAMLERIVSETDVAKREKAAAQ
DLERQLQDEHAQISEDAHRLSIELAEAEPALREADAALSTVKPEYLREIRAYAMPPPMVK
RTLEAVGALMGEKNCEDWDSLKNCIRRDDFLASVRNFRPDDITEPARERVRGMMRDSKFT
VEAAYRASKAAGPLMQWVFFQVKYSAIYQRVAPVRSKIEKLIKARDVKLKGLEVAQEEVR
EKENSLQQLMGEYQNATAQIAELKQRIAAVSAKCNRAQTILRQLLDERDRWEKEVHSFDS
EARTTLGDCVVSAVFLAYTGFYDEHTRERVLMPRWLACLQRATIPVRKGLSVTEYLSPAT
QQLAWQEAGLPKDRLNIDNAAIMHRCQRYVLLIDPTDVAAHFVLRYYGAQKITKTSFSRP
GYVKQLEMAVRFGYPILMEDAEHLDPAVAPLLNGEVRCHGTRHITRIGPHEVDLAPSFHL
FLHTRNPNFQPPPDLAGQVCMVNFTVTLSSLQSQCLHYTLLHERPDVDAKRSKLLKAQGE
YQLRLRVLEEKLLTRIAEAEGSLLDNDALIESLTELKEEATCIAGDIADSENSMREIWGV
EDMYRPIATVVAQAHFALQRFEELNPYYCYDVRFVLRVLGDALRALPATSTPAADGGLRL
QQLTYGIFVLLHRRVVRGMFHEDHLVWVLRLAQLRSAMSATGAKSASAAPTAAPMMALPT
GSTGGSAVMPEEWEWILSCLRLAGSGVGAAGAGAGPPSTAASRTMTTDSSEDGGASNPIT
LATTAASLPPVVRQACPALGSQSCQALAFLLTKPAFNEVRETLTTRAAAWEAVLTSATPV
ATSESALPAECFPRGASRVRRLLLLALILLNTRRDAFIEAVRQLLASYFSPKEMGTAAAA
GADGAAALFTDDFFAPQTNDLADGIMAELSAATPLLMVTDTMFDPALRVEELAQRTDTNL
NVVAMGSMESIENADAYLAEATKLGGWVLLKNVHLARGYMDKLEKQLHFQRSEGQLHKEF
RLFLTAERDRSAAKSSATATAAAASSKVLPINLIEASVVVVYEAPPGMQSSLLQTYGEYP
AVGTAAFDGAGASSVVPSAGAAAVSSNTSLQRLYLAAAWLHSVITERILYKPLGWSEAYE
YTEVEYQRVVQAVQAWSSAAPAAAATASSSNAGALKVSWDALRTIVATTVYGGKVSNIFD
QHVLNVFCRRLLRPEMLQDAAQFVSEAAAAGVPPPPIRGRSRAELLQWIHALPGGSSHPA
WLALPIGADRMTRARSAIEVVERLSLVQSTLNDELTFADIDGDAQAAAGGAGSTSLRSGA
LRATRWAAKVQSYCTAWYPTLRDALEKLEKHPFVLQAIALHEQETVERASAADVGAAKEI
RVNLSVASHPGGVAAPLVLAMQREVVAAVELVRHLVACVRELREVVMEERTPSSAHRGLV
EELMKDHVPDVWAAHLRGVHGSAAHSLFVGLWIADVQQRVEHLLELATAAHGGQLAKTPV
RLGALFSPGAFLTAFKQHCARAEQVPLEQLVPQVEVAAATGASAGGALRTASSALSAAGI
PGAPATSAASLAPPRDNEMVFTGLTLHSAQVDVEGKCTLSGATTSGAAPALSSAVVLRWR
WVRSTESVATTTALTARLELQTEQQQSILLPFYTTENREALLEVLELPKAPNSGITSGDS
DAGVHAWYERGVCVAAWSASE
NT seq
16986 nt
NT seq
+upstream
nt +downstream
nt
atgttccccttcgatgacgatgtcgtgcagttcattgtgttgctcacacagcacggcacc
gtggagaaggtccgcgcagccattgcgcagagtgccgatgcgatggactttgcctcgcct
cccgcgtcgccggagggtgtgatgcacctggccgccgggcagcgacggaacatcggagag
cgcggccgcggtgacgatggcgaaacgggcgtcgtttcgaaaacggccctcctcggcgcg
cacgttccgttcatcgccgtctgcgagatcgcagacgaccgtgcggccgctgacgggtcg
cagatcatcgcaacagcggacccggcgaccttcttccgaagcgtctcctgcatggaggac
gccacgccggaggaagcggtgagcctcggtgcgactgcgcgcggcggcaccggcgcccgt
cgcagcacaggaggtggtgcgggtgacgacagcttcccgagcgcacgacataaggcgaag
gccctgagttgcattcttctcgagcgacgcgaccctcatggcgtcggaggcggcacaact
ggtggtggtggcgctcgcgcgctctctgtgcgcgacctatacatccagtccatggacctg
cagcgccccctggataccctgcagtccatcttgcgcaacatctacgaccccatgctgcgc
tcccacaagactcagtccgcgttgcgtacgcacgtgcaggacctcctctccagcatctgc
tcgatgcacaacgtgctgccggaaatcgacgtcacccgctacgtgcacgaggacctcctg
cagttgtgcgacgcgaaccctctgcttgatgtgccgcagcttatcgaccggcttggcgag
gtggccaaggaccccagcttcatccgtcgcgtgctgcaggtgcgcaaccgctgcaaagag
gcgctctcgatggagccgcttctgtccgggaagctggaagaggaagagctggcgaaggaa
ctgcagagcaccaacagcaaaaccattggttccccagcggtgggcccgacgagtctcccg
agtggtttgtcgggtgctcattcgcagcccagcgcctccgctgcgcctggcaaaggcgca
gcggccggcatcgcgtatgacggcgacggcggcgacgacagcgcgcaggttgtgcaggag
cgcatcgtgtactggcgatgcgtgcacgcgtggatggaggacgtcctgcggcaattgcgt
gggcgtgagtggcggctggtgcaccgactccttgcccagcgggtagaaacggactacgtc
ggcgagtacgttggctacttgaagctggtgcaggagtacatcaccttcctcaacacgatt
ccggagaagcggcttgccaatgtgcaggacatgaaagagttcaacgacgtggcggacgag
atcatcgtggcggcgacgcagccgacacgatttgcggcgcggctgcagctgagcctactc
acgtcgctcgtgtggcagatctcgtcgcgatgggtcagcgtgatggagacgcagcaggtg
cttcgcctcgacgaagaccccgacgccgccccagtcgcagcggccggtgacgcgaatgag
actcagcacagagccgacgtaactgcaggagtccatgctgatccgttcgtgcccctgcag
atactgcgcatcgccatacactcgctacgcacgctgcaggcccggtacgtggagcacagc
actcagctacggcaccagatccgcgtggtgcgcaaccctcgcgagcacgtagagcacccg
cgtgtggaagcgctgctcgcgcgctgcctcgcggtacgggacctgatcgaagaacacctc
ctcctcatgcggcagcttggcgtcgtgttctctaccaagatacgcctgcagtttgccaag
gccaagcgtgacgcagtgacggcaatgggagctgcagctgcgcagcagcagccaggtgag
gagtatgcactggtgatgcaggacgccttcaacgagtgtgtgcgcgccgtgtgcgggtgg
gcggacgatgcggaagacctgcagcggtcgcgcaagggcagcgtcggcgaatctgcggcg
tcctctggcagcccgcatcgcgggcacaagggctgcggcaattacctgtggcgaaccagc
cccacagccgtccagcgcttcaatgcagccgtgcaagagtaccagcacaagcgcagtcag
tgcgacgagcagatcgccttggtggtgagccagctgctgagtaaccagcagcacgcacat
aatgactgtcgaagcggcatgggcggcgcgggggcggcgggggtggctgggatggccggt
gcaggagcggcgctgaaggggccgcaggtcagcgccaactacgctgacaatcacggcctg
cgcctcttccgcaccttcaaaagctttaagatgctgcccctcgagcgggtgcagcgggtc
gtgcacagctaccaggacgccgttgcggaaaagctcagcgcctatgtcagctacgtccaa
gactgctacgtcaacgtgcccctcacaaagcaggaggtcagctacaacatggcacgcttc
tccgtgtcggcgttggtggcgcagatcatgtgggagcagcgcctggcggaggcgctcaca
aagtcgatgatgcgcttcgactacgtcagcgagcatggatggcatcagctcttgtacctt
cggaacgtcgagcactactggcgccttaacgccagccttgccgagttcatcggcgtccca
ctcgacctgcttgtttgtgatgagctgcagctcgactccgaggtgcacggctgcgcggtg
gcgctggcgtgcttgagtctgcactacacggaggaagcaagcgagtgggagcaggatgaa
cacctccgtatcgcgcaggacctcgtggccacccgcgatccaggcgcccttgccgttgcg
cgggatcgcatgctgatcggtggtgcgccgcgactgtacaagactaccgcacgcgtccgt
gacatccgcagttcgcgcgacattattcagcagcggatcgagagtcacatggcgagttgg
ttcgaggaggtcgataggctgatcggcggcagcggcctcgatcagcagacgctgctgctg
tcgggccccgtgctttgggcggtcaactgcgggcccttcagcgcgccgcacaacacaaca
ggcggcgcggtcgccaatgaggcagactccgccgtgatgcgtctgcagccctctggtggg
gccggcgcgatgacgggcggcttcacggccaacgcgaactacttcaacaccggtggcgcc
ggcagcatgccgcgtgccagcagcttcagtccgtcctctttagcgctgctgcgcgcacaa
ggccgcagcgcgtcgccgtcggtgcgccgggcctcgttcttggtgcctgtcggcagcggt
gacagcgagtccttggcaccggcggcggcgacggcggcgagctggatggtggaggttgcc
ttcccgtggagttttccaatcatagctgaggatctgcgttatctggagtcttcacacctc
acttccaccctgctcagtgacggctctggagagccggcagcgacgagccggagcagtaac
agtgctgcggtcactacgccgtcgcctcgtggacggtgcaccgctgtcgcctctggtctc
gccttcctgcgggacgctctgcgtggaaacgagctgcgatcacgcctggcgcacacgcta
gtggagctcattcacgtctactacgtcaccgtcaagggcgaggacaccagtttggttctg
ctggcgaccgacgagtaccaggaggtaaatcggctcttccagatgggtattgccctgcgc
tggagcgacgagggactgctgagctacgtgcagcagctgtccgacacgatgcaggccttt
accacgacggtgcagcagttgcgatccaagacggagctggtgtaccgcaagattcgcgcc
ttcctcgtacgggcctttcacccagaggcgatcctgcagcgagtgaaggcacttcgccgc
atcgtcgacaccctcgccctgcgctgtgtgcatgcgcatctgtggacacgccagattcag
ccactgctggagcaggcgctgcttactcagatgaagtatctgatgcattcgtggaccgaa
gacttcctgtccatgcgcggcgacgtccgctttctcgagaagggtgcggagacggacgtg
tttcggctgacgccgttgcgggttcgcatgcgggtggtttacaaggaggtccgcctcgag
tcctgctgcggcgcgtggcgtcagcactggatcggcgagcttaaccgcttcttcagctgg
atcgacgtactgccgcggctgtacaaggaggaggagactcaggcggacgtcgtcggcgtc
tcggccgcactcggctctgacatgacgagcacggcgggtcgcatcagtctgacgccaagt
catcgtgacaactctgtgccgccggcagcggcggtgacgcatggcagcaacggtactgac
ggcgctggcatcaacgcaggcatcggtggagccggcagcaatggccacaacgctgccagt
ggccgcacacccgacgatggctaccaatacctacttcttcggctgccgtcgtctgcgctg
gcagagccgctgcacgcgattgagcagtgtgtgcaggacgccatcgacacagagaacgag
tggcgtcgtgggcaacagtttctgagcatggatgtggcgctcatgcagcagcgctttggg
cgcgacctgcgccgctggagccacgccctgcgcctcatgcacacggtgacgtcacgcatc
atggactacacgcagccgaacaagcttctcggcggtattgtaatcctcgcgcaggaagca
cagattgagttgggccgaaagctggaccaggtgagtcagtatgcccatgcgaagtttaag
gacctgctgcagggggagcaggaacgggccttcagcgtcatcactcaggagcggacgaag
atcgacgcgctcgacgtgatcagcaacgcgaaggatgcagccgcgtttctatcggaggca
ccgcgactcaagagcgagctgcagaagctggacggcgaaatcacgctcatgggcaacggc
gaggtgagtctgcagaagctcggccacgtgttcccggaaaactggatgtacgccgcggcg
ctgcgtgaggagtacacgtcgctagcagagcttgtcgaccgcaagctcaaggcggtgcag
gtgcgccggcccttcctgatcgaggaggcgaaatcggcagccagcgccctcgaggtcaag
gtcgcggaggtggatgcgcgcttccacaacgtggactccatcgccgtctccaaggaggcc
cctgtgttggcgaagcagctggtctccgatatctacgaggaggccgttgccttcagcgtg
gaggcgaagcaggtgacggcgatccaggaggcgctcggtgagtcgccgcacgtctttgcc
tctttgcagaagctgctggcagacgtggcgcttgtgaaggatgtgtggggccacgtcgtc
tccgcctacgtggagctcaacgagctcggcgcgacgccgttcttcgagatggtgccgcgc
cgcctacatgagcgcctgcagcaaatcgatgaggaaacagatgcgtaccaggagacgatg
cacagttaccagctctaccaaaacctcaagcagaagctgtgccgcgtgctgagctacaac
cgcctcatgcaggatctccgctcagacgctatgtcgccgctagagcgctccatgcggcac
tggacagcgctccagcacaagctgcgcgcaccgtgggtgctcgcaagcctcacagtggcg
aacatctgggaaagcgacccgggcgccaacgcagccgtttatagcgaagtggttgagacg
gcccagggcgagcgccgcatcgaggtgcagctgcacaacatcaacaactactggaacatg
ttcgagttcagcgtggtggtctacaagaagcaggtcgcgctcatacgcggctgggacgag
gtgttcgagcggctcaccgaggacctgagcaccttcggcggcatgcgcgcgagcccgtac
tttgtcttcccgcagctcgtctccatggtcaacgacgccgaagcacgactggataggctg
cggcaggtgctggaggtcctcctcgaggtgcagaagcgctgggtctaccttgacggcatc
ctgtctgaaaacgcggaagtccgcgcgcagctgccgcatgacaccgtcaagtttgaccgt
accagccgcgaactgctgcacatccttccccggccccggtcctccggcaacctgccagag
ctacacgtctccttctttctcgaagatgagaagctgaaggcaacgctggagcgactcctc
tcacagctggcggccgtgcagcgagcgctgacgagctacctcgacacacagcgcagccgc
ttccctcgcttcttcttcgccggtgacgacgacctgctcgaaatcatgggcaacagcaag
aacccactcttcctcaacaagcacctgaagaagatgttcaccgccttagcagcgctgcag
ctggacggaaatgtaaaagacgccacgacgcggctgcgcggcttctcaagtgccgagggg
gaggagctgtcttttcagccgggccccatctcatacgggcatcggccgatccacgagtgg
ctcggtgaggcggaacagggcatggtccacaccctccgcgaggccacgctgcgcgcgtac
aacgagcttgtcagcacgaaggatgcgtcgccgtacgccttgctgtggtcgatggattgg
gtgcggcagaagccgacgcaggtgttgtgtctggcgctgcagctcttgtggacgcgggag
caggagagtctcttgactggtgcgcacggcggcagtgccggtgccgcggatgcccggcgc
acgtctcgggcctcgtcatcaaagttgtcggtgttgacaagcagcatggacgacctgctg
gctcgcttggctggcaatgtgctgggcaacgccgttgctccgagctcgcgtcgccagtgc
gagcagctgatcactatagccgtgtaccagcgcgacgtctctcgcaccctcgctgcacgc
aaggtggcgtcgcgcaacgatttcaactggctcagcgttttgcgcctgtacgtggtcccc
acacaccaccagcagcagcccggcggcaagagcatgagtagcttgagcaacatcggcctc
gcccacagcacgaacgtgagtgaattagtgctcagcgagtaccggaccgccgagacgctg
gagtgccgcatggcggatgcgtccgtgcttcatggcttcgagtacatcggcgcgtatgag
cgcctggtgcagaccccgctcacggacaagtgctacctgaccctcatgcaggcgctgcac
acccgcctcggcggctcgccggttggcccggccggcaccggcaagacggagacggtgaaa
gcgctcggcatgcagctcggccgccacgtcctcgtcttcaactgtgatgacactttcgac
taccaagccgttagccgaatcttcctcggcttgtgccaggtcggtgcgtggggctgcttc
gacgagttcaatcgccttgaggaacgcatcctctccgcgctgtcgctgcagatccaagtc
atccagcagtcactgcgtgcgcggcagcgggaggtgcagctgaaccaccgcgccgtgccg
ctgcactcgaacgtggccatcttcatcaccatgaatcccggctacgccggccgctccaag
ctgccaggcaacctgaagcagctcttccgcaccgtaacaatgaccatccctgaccgcgag
accattgcagaggtgatgttgtttgcgcagggcttcgccacggccgaggcgctctcacaa
aaagttgtcccgctcttccggctgtgcgaggagcagtttacccggcaggcgcactacgac
ttcagcctgcgcgctttgaagtccgtcctggtagccgcgggtgaccgcaagcggcaggtg
gcggtggcgtcgcgcggaaaccacggcagtcacaacgctgctggcggcgcgggtgcggac
gcggtgcaggaaacggagcgaacgctgctgctggagagcatcatcgcgaccgttgccccc
aagctggtcgcgcaggacgcggcattgttttacccactgctgcacgacttcttccccggg
tgctcactgccggcgctgccgatgggcgagctgcgcgaggccgtagagtgcgtgtgcgcg
gaaagcggcctctccactgctgcggggtggatggagaaggtgctgcagttttaccacaca
aagatgacgcgacacggtgtcatgattgtgggccccagcggcacaggtaagacgacggcg
tggaaggtgctgatggcggccatggttcgcctcgagcgggcgctgcagatgcacgcatac
gtcctctctcccaaggtccttagcaagggcgaactcttcggcaccctcgacgtgacgacg
cgcgagtggcgcgatggcgtctttacaagtatcctgcgcaagatcatcgacgcagaggaa
cagcagcagatcccagatgacttggagctggcgggtaacgacgacactgaccacaaagtc
gtggcggcgccgtcgatgggcgtcgacaacaagaagcgcgtttcgctaaagcggaacctc
acttgtggcggcgacgccagcgaactgcgggcccaagacttggaggcgcgaaaggagcac
tggatcatcttcgatggcgacgtggacccagagtgggtggaaaaccttaactcggtgctg
gatgacaaccggctgctcacgctgccaaacggtgagcggctcccgctgccgcgctctgtg
cgcatcatcttcgaagtgcaagacctgctgtacgcgacgccagccaccgtgtcgcgctgc
ggcatgctgtggttcagcgagggcgtagtgccgctctcaggggtgctggcgcacacgtat
taccagctgcaggaacacccgatcgtcgacgcgcgtggtcgtcacctacactggggcacc
gaccacatgatcggcgtcaccggggcgcggagcgccctctacgcggaatgccttgtgagt
ggtgaatacggcaaggtgtatcacgagttcgtcctgtcgagcaccaggaccagcgctgag
gaagtgatggccggcagtctgccgcggcatcatggccgcaccagctccggcgacgaaggc
atcaccgccttagagacgccgaagcgcagcagtcacttgtgcaaggacgcgaccccgcga
aacgacaaggccgccgagctcgacatgggcgacaccctctacggcacgacaggtcacggg
agccacaccatattcacgagcaccagcggcggcggcgccagcacgctccgtcgcagccac
cctgatgcggagcgcatccaggagctcatggtcagctcgtgggcggcggccttcgagaag
gacggcgctgtggtgcgcgggctgcagctgatgaagtcggcggcgttccgcggcgtgtgc
gtgatggtgccaagcgacctacagtgcatccagagcatggtcgcgtttctggtccagggc
gtatggcgcaccttcgaaaccgaacagcaaaacaacggtgacgtcttcagcgacgccgtg
gtgaagaagatcgcgatgcaggtgctctcttacgcgatcttctggggtctggcctcagcc
atgagcctggagaaccgcatgaagctggcgcagcagctagggctgcggccgactgtcgac
ggcgttgcacagtcgatgttggaggtggaggtgtgctaccgtacgggcgagtggcggctg
atccgcaaccgtgtcaaggagatctcactcctggcggagcaggtgggcgcgaacgacacc
gtcataaccactgtggacacgtgccggcacgaggacgtgctgagcgcctggctcggcgcc
ggtcgctccgccattctgtgcgggccgccgggctctggcaagaccatgtcgatcactgca
gtgctgagcagcctgcccgagtacgaggtggtcttcctgaacttctcgagcggcacgacg
gtgaaaacgattgtgaaggcgctggagcagcactgccgtgtgcaggataccgcgcgcggc
ctcgtgatggcgccgacgtccggcaagcagctccttctcttctgcgatgaggtgaacctg
ccggcgctggaccgctacggcacgcaggtcgtcgtgcagctgctgcggcagctcatcgag
cgcaatggcttttaccgcgcgcgtgacaacacctggatcaccgttgaggacgtgcaggtc
gtcggcgcctgcaacccgccaaccgaccctggccgtgtgccgctcagcgcacgcttcctt
cgttgggcgccggtgctgctcgtcgactttccgtctccagagtcgctcaagacgatctac
acaacctactgtcgcgccatcctggcgtggaatgaacgcctcagcggccaagtcgccacc
cacctggcgcaggcgatggtgaagatgtaccgcgtctctcaggccaagttcacgccgata
cagcaacctcactatctctattcgccccgcgagctgtcgcgctggtcgagggcgctgtac
gagggcatcctcacctgggacgacacggtgcggcgccagctcgatgtcagccagctcgtg
cgcctcgccgtgcatgaagggctgcgcgtgtttgccgaccgcctcgtcacggcggaggag
cgggcatggacgggcacggccattgtgaaggcgtttcgcgagttcttcaccgacgtcgac
gaccacgcgttccatcagccgctgctctactccacgcttctctcgcgcagctacacggac
agcccacgggaggaactgcgggagtacgtgcagaagaagctggcagcgttcaacgaggag
gagtcgctgggcaacttggtcatctacgacgcgatgatcgatcatgtcgtgcgcatcgac
cgcgtcctgcgccagcccctgggtcatctgctcatcgccggctcctctggtgtcgggaag
acggccttgacgaagctggtggcgtggatgcgcggcttctcgaccttcacgctgatgttg
caccgcgggtacgacttggacgacttcgaacacgacctccgcggggtgctgcgccgcgcc
ggatgcaagcgggagcgcatctgcttcctgttcgatgaatccaacatcctgcagccgagc
tttctcgagtacatgaatgccctcctggcgtcgggcgaagtgcccggccttttcgacggc
gacgagtggtcgaaactcatgcaggaggttcgcgatgcggtactggcgagccagagctac
tatgccacatcgcgtggtgccggcgccggcgctgttgcggcaggaagagcaggtggcggc
ggcgaggcaggccgcgacagggactcgtcggtactccgaggaggcggctgcaagggtctg
gacggcaacgacaacggtgacggcgtcaccggttgccggcgcgcctctgcggtcaccggc
gtcggcgtcgcggcgagcgcggcggcggacaacttggttgacgtgcacaacgaagcggaa
ctgtaccattggttcctgacgaacgtgcgcgagtacctgcacgtcgtgctcacaattaac
ccctcctcaggtgagttcacgtcgcgcacggtggcgagtccggcgctggtaaaccgatgc
accatcgactggttcggcgactgggacacggcgacgctgcagcaggtatgccaagagcgg
atttgccgtctcgcgctgctgcccgcctgccacggcgtcttcgcaaccgaggtggaggca
aaggaggcggtcgtggagagcctgtgcgccattcacgtcgccacgcagcacattaaccaa
gctctgcgcgtgcgacacgccaaccagggcaccttcgtcacgccgcgtcactttacggac
tgcgtctcgcacttcgtggccatcttccaggaaaagaagaaggtctccagtgatgccctg
gtgcacctgcgcagcggcctgaagaagctcgagttgacggcgcaagaggtgtcggcgcag
cgggcaacgctgcaggacaacgaggctgagatcgaggcgagcagccggcgagcgcaggcg
atgctagagcgcatcgtcagtgagaccgacgtcgcgaagcgtgagaaggccgcagcgcag
gacttggagcgtcagctacaggatgaacatgcgcagatctctgaggacgcgcatcgcctg
tccatcgaactcgcggaggcggagccggcgctgcgggaggccgatgcagcgctcagcacg
gtgaagccggagtacctgcgcgagattcgcgcatacgcgatgccgccgccgatggtgaag
cgcacgctcgaggctgttggggcgctgatgggtgagaagaactgtgaggactgggattcg
ctgaagaactgcatccgccgcgacgacttcttggccagcgtgcgcaacttccgccccgac
gacatcaccgagccggcccgcgagcgcgtgcggggcatgatgcgagacagcaagttcact
gtcgaggcggcgtaccgtgcctcgaaggcggccgggccgcttatgcagtgggtgttcttt
caggtgaagtactccgccatctaccagcgtgtggcgccggtgcggtcgaagatcgagaag
ctgatcaaggcgcgtgacgtgaaactaaaaggtctggaggtggcgcaggaggaggtgcgt
gagaaggagaactcgttacaacagctcatgggcgagtaccagaacgccactgcacaaata
gcagagctgaagcagcgcattgccgccgtctcagccaagtgcaaccgtgcgcagacgatc
ctgcggcagttgctggacgagcgcgaccggtgggagaaagaggtgcacagcttcgactct
gaggcacgcacgacgctgggcgactgcgtcgtgtccgcggtcttcctcgcttacaccggc
ttctacgacgagcacacacgcgagcgcgtcttgatgccacgctggctggcatgtctgcaa
cgcgccaccatccccgtccgcaagggtctaagcgtgacggagtacctctctcccgccacg
cagcagttggcgtggcaagaggccgggctgcccaaggaccgcctgaacatcgacaacgcg
gccatcatgcaccgctgtcagcggtacgtactgctcatcgacccgaccgacgtggctgcg
cactttgtactccgctactacggagcccagaagatcaccaagacctcgttcagccgacct
ggctatgtgaagcagctcgagatggcggtgcggttcggctacccgattcttatggaggac
gccgagcacctcgaccccgccgtggctccgctgctgaacggcgaggtacgctgccacggc
acacgtcacattacccgcatcggcccgcacgaggtggacctggcgccgtcgttccatctc
ttcctgcacacacgtaacccgaacttccagccgccgccagacctggctgggcaggtgtgc
atggtgaacttcaccgtcacactatcctcgctgcagtcgcagtgcttgcactacaccctt
ctccacgagcgccccgatgtggatgcgaagcgctcgaagctactcaaggcccagggcgag
tatcagctgcggctgcgcgtgttggaggagaaactgctcacccgcatcgccgaagcggag
ggcagcctgctggacaacgacgccctcatcgagagcctgacggagttgaaggaggaagcc
acctgcatcgccggcgacatcgccgacagcgagaactcgatgcgtgagatttggggcgtg
gaagacatgtaccgccccatcgcgacggtggtcgcacaggcgcactttgcgctgcagcgc
ttcgaggagctcaacccgtattactgctacgacgttcgcttcgttctgcgtgttttgggc
gacgcgctgcgggcgctgccggcgacaagcacgccagcagcggatggggggctgcgtctg
cagcagctcacgtacgggatctttgtgctgctgcaccgacgcgtggtgcggggcatgttt
cacgaggaccatctcgtgtgggtgttgcgtctggcgcagctaaggagtgcgatgagcgcg
acgggcgccaagtccgcgtctgccgccccaacggcggcgccaatgatggcgcttcccacc
ggcagcaccggcggctccgctgtgatgccggaggagtgggagtggatcttgtcgtgcctg
cgtctcgcgggaagcggtgttggggctgcgggcgccggcgccggccccccatcgacagcg
gcatcccgcacgatgacgaccgactcctccgaagatggtggggccagcaaccccataaca
ttagcgacgacagcggcaagtcttccaccggtagtgcggcaggcctgtccagccttgggg
tcgcaaagctgccaggcgctcgccttcctgctcacgaagcccgccttcaacgaggttcgc
gagacgctgacgacgcgggcggctgcgtgggaggcggtgctcacgtctgccacgccagtg
gccaccagcgagtccgccctgccagcggagtgctttcctcgcggcgccagtcgcgtgcgc
cggcttttattgctggctctcatactgctcaacacgcgccgtgacgccttcatcgaggcg
gtgcgccagctcttggcgtcgtacttctcaccaaaggagatgggcacagccgccgcggct
ggagctgacggtgctgccgccctcttcacggacgatttcttcgctccgcagacgaacgat
ctcgctgacggcatcatggctgagctctccgccgcgacgccgctgctgatggtgaccgac
accatgttcgatcccgccctgcgcgtggaggagctggcgcagcgcacggacacgaacctc
aacgtcgtggcgatgggcagcatggaaagcattgagaacgcggacgcctacctggcggag
gcgacgaagttggggggctgggtgttgctgaagaacgttcacttggcgcgtggctacatg
gacaagctcgagaagcagctgcacttccagcggagcgagggtcagctgcacaaggagttc
cgtctttttctcacggctgagcgagacaggagcgcggcaaagtcttccgcaacagccaca
gcggcagcagcctcatccaaggtgctgcccatcaatctcatagaggcctctgtggtcgtg
gtctacgaggccccgccaggcatgcagtcatctctcctgcaaacctacggtgagtatccc
gcggtcgggacggcggccttcgacggcgccggcgcatcctcggtcgttccgagcgccggg
gccgccgccgtgagcagcaacacctccctgcagcgcctctacctggccgcggcttggctg
cactccgtcatcaccgagcgcatcctctacaagcccctcggctggagcgaggcgtacgag
tacacggaggtggagtatcagcgtgtcgtgcaagcggtgcaggcatggagctcagccgca
ccagcagcagcagcgacagcgtcgagcagcaatgccggcgccctaaaggtctcctgggac
gccctgcgcaccatcgttgcgactaccgtctacggcggcaaagtgagcaacatcttcgac
cagcacgttctcaacgtcttctgccgcaggctgcttcgtcccgagatgctgcaagacgcg
gctcagttcgtctctgaggcggcggcggccggtgtgccaccgccacccatccgcggacgc
tcccgcgcggagctgcttcagtggattcacgcgcttcccggcggcagcagtcatccagca
tggctggcgctgccgatcggcgcggaccgcatgacgcgcgcgcgcagcgccatcgaagtg
gtggagcgcctgtccctcgtgcagagtaccctgaacgacgagctcacattcgccgacatc
gacggcgatgcacaggccgcggcaggcggcgcgggttccacctcgctgaggagcggcgca
ctccgggctacgcggtgggcagccaaggtgcagtcctactgcactgcctggtaccccacc
ctgcgcgatgcgctggaaaagctggagaagcacccctttgttctacaagccatcgcgctg
cacgagcaggagaccgttgagcgtgccagcgccgccgacgtcggtgccgcaaaggaaatc
cgagtcaacctcagcgtggccagtcatcccggtggtgtggcggcgccgcttgtgctcgcg
atgcagcgagaggtggtggctgcggtggagctcgtgcggcacctcgtggcgtgcgtgcgc
gagctacgcgaggtggtgatggaggagcggaccccgagctccgcgcaccgcggcctcgtg
gaggagctgatgaaggaccacgtgccagacgtgtgggccgcgcacctgcgtggtgttcat
ggctcggctgcccattccctgttcgtcggtctctggattgccgacgtccaacagcgtgtc
gaacatcttcttgagctggcaacggccgcgcacggcgggcagctggcgaagacgccggtg
cgtctcggtgcactcttctctcctggcgcgttcttgaccgccttcaagcagcactgcgcg
cgggcagagcaggtgcctctagagcaactggtgccgcaggtggaggtggccgcagcgacc
ggcgccagcgcaggaggggcgctccgcacggcatcctccgccttgtcggccgcgggcatc
cctggtgcgcccgcaacctcggctgccagcctggcgccaccgagggataacgagatggtc
ttcaccgggctcactctgcactcggcacaggtagatgttgaaggcaagtgcacgctgagc
ggcgccacgactagcggtgctgcccccgcgctctcttccgccgtcgtgctgcgctggaga
tgggtaaggagcaccgaaagtgtcgccacgacaacggcactgacggcgcgcctcgaactg
cagacggagcaacagcagagcattctcctgcccttctacacgacggagaaccgcgaggca
ctgctggaggtgctggagctgcctaaagcgccaaatagcggcatcaccagcggtgacagt
gatgccggcgtccacgcgtggtacgagcggggtgtgtgtgtagccgcgtggtcggcatct
gagtaa
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