Leishmania donovani: LDBPK_251790
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Entry
LDBPK_251790 CDS
T02289
Name
(RefSeq) pyruvate dehydrogenase E1 beta subunit, putative
KO
K00162
pyruvate dehydrogenase E1 component subunit beta [EC:
1.2.4.1
]
Organism
ldo
Leishmania donovani
Pathway
ldo00010
Glycolysis / Gluconeogenesis
ldo00020
Citrate cycle (TCA cycle)
ldo00620
Pyruvate metabolism
ldo00785
Lipoic acid metabolism
ldo01100
Metabolic pathways
ldo01110
Biosynthesis of secondary metabolites
ldo01200
Carbon metabolism
ldo01210
2-Oxocarboxylic acid metabolism
Module
ldo_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
ldo00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
LDBPK_251790
00020 Citrate cycle (TCA cycle)
LDBPK_251790
00620 Pyruvate metabolism
LDBPK_251790
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
LDBPK_251790
Enzymes [BR:
ldo01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
LDBPK_251790
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Motif
Pfam:
Transket_pyr
Transketolase_C
Transketolase_C_1
PFOR_II
Motif
Other DBs
NCBI-GeneID:
13388755
NCBI-ProteinID:
XP_003861509
UniProt:
A0A3S7WZ91
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Position
25:complement(671174..672226)
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AA seq
350 aa
AA seq
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MRRFASRALFSASAAMAARCATTNMTVRDAIHSALDEELAREEKVFVIGEEVGQYQGAYK
VTKGLVDKYGKDRIIDMPITEHGFAGMAVGAALSGLRPVCEFMTFNFAMQAIDQIVNSAG
KSLYMSGGQMKCPIVFRGPNGASAGVGAQHSQCFGPWYASVPGLKVIAPYNCEDARGMIK
AAIRDDNAVVVLEHELLYSESFPVTDEVADKNFVIPFGKAKIEREGKDITLIGFSRGVDL
CLKAAEKLAAEGVQAEVINLRSLRPLDRHTILSSIKKTHRAVTVDESFPVCNIGAEICAC
VMESDTFDYLDAPIERVSCADCPTPYSKDIEMASQPQVADVMAAAKRVLS
NT seq
1053 nt
NT seq
+upstream
nt +downstream
nt
atgcgccgcttcgcctccagagctctgttctctgcgtccgccgccatggcggcgcgctgc
gccacaaccaacatgacggtgcgcgatgcgatccactcggccctcgacgaggagctcgcc
cgcgaagagaaggtcttcgtgattggtgaggaggtcggtcaataccagggtgcctacaag
gtgaccaagggccttgtggacaagtatggcaaggaccgcatcatcgacatgcccatcaca
gagcacggcttcgccggcatggccgttggcgccgctctcagtggcctgcgccccgtgtgc
gagttcatgaccttcaacttcgccatgcaggctattgatcagattgtcaactcggccggc
aagagcctgtatatgtctggtggccagatgaagtgccccatagtctttcgcggtcccaac
ggtgcgtcggctggtgtaggtgcccagcatagtcagtgcttcggcccgtggtacgcgtcc
gtgcccggcctgaaggtaattgcgccgtacaactgcgaggatgcccgcggcatgatcaag
gcggccatccgcgacgacaacgccgtggtggtgctcgagcacgagctgctgtacagcgag
tcctttcccgtcacagacgaggtagcggacaagaactttgtgatcccgttcggcaaggcg
aagattgagcgcgagggcaaggacattaccctcatcggcttctctcgcggtgtggatctg
tgcttgaaggcggctgagaagctcgccgcagagggtgtgcaggcggaggtgatcaacctt
cgctccctgcgcccgctcgaccgtcacaccatcctcagctccatcaagaagacgcaccgt
gcagtcacagtcgatgagtccttccctgtgtgcaacattggtgctgagatctgcgcctgt
gtcatggagagcgacacgttcgactacctcgatgccccgatcgagcgcgtgtcgtgcgcc
gactgtccgacaccgtacagcaaggatatcgagatggcctcgcagccgcaggtggccgac
gtcatggccgctgccaagcgcgtactcagctaa
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