Leclercia sp. J807: GNG26_03090
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Entry
GNG26_03090 CDS
T06440
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
lea
Leclercia sp. J807
Pathway
lea00260
Glycine, serine and threonine metabolism
lea00261
Monobactam biosynthesis
lea00270
Cysteine and methionine metabolism
lea00300
Lysine biosynthesis
lea01100
Metabolic pathways
lea01110
Biosynthesis of secondary metabolites
lea01120
Microbial metabolism in diverse environments
lea01230
Biosynthesis of amino acids
Module
lea_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
lea_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
lea_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
lea00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
GNG26_03090 (thrA)
00270 Cysteine and methionine metabolism
GNG26_03090 (thrA)
00300 Lysine biosynthesis
GNG26_03090 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
GNG26_03090 (thrA)
Enzymes [BR:
lea01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
GNG26_03090 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
GNG26_03090 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
DUF6247
Motif
Other DBs
NCBI-ProteinID:
QGU09388
LinkDB
All DBs
Position
654602..657064
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AA seq
820 aa
AA seq
DB search
MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKITNHLVAMIEKTIGGQDA
LVNISDAEQIFASLLQGLADAQPGFPHAQLKAFVEQEFAQIKHVLHGISLLGQCPDSINA
ALICRGEKLSIAIMAGLLEARGHNVTVIDPVEKLLAVGHYLESTVDIAESTRRIAAGKIP
ADHMILMAGFTAGNEKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRQV
PDARLLKSMSYQEAMELSYFGAKVLHPRTIAPIAQFQIPCLIKNTGNPQAPGTLIGASSN
EDGLPVKGISNLNNMAMFSVSGPGMKGMVGMAARVFAAMSRNGISVVLITQSSSEYSISF
CVHQADCLRARRALEEEFYLELKEELLEPLSIQERLAVISVVGDGMRTLRGISAKFFAAL
ARANINIVAIAQGSSERSISVVVNNDDATTGVRVTHQMLFNTDQVIEVFLIGVGGVGGAL
LAQLKRQQEWLKKKHIDLRVCGIANSKALLTNVHGLNLENWQAELAEAKEPFNLGRLIRL
VKEYHLLNPVIVDCTSHQAVADQYADFLREGFHVVTPNKKANTSSMDYYHQMRHAAAKSR
RKFLYDTNVGAGLPVIENLQNLLNAGDELQRFSGILSGSLSFIFGKLDEGMSLSEATKMA
RELGYTEPDPRDDLSGMDVARKLLILARETGRELELSDIVIEPVLPESFDHSGDVATFMA
NLPQLDDAFASRVAKARDEGKVLRYVGNIEEDGVCRVKVAAVDGNDPLFKVKNGENALAF
YSHYYQPLPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGV
NT seq
2463 nt
NT seq
+upstream
nt +downstream
nt
atgcgagtgttgaagttcggcggtacatcagtggcaaatgcagaacgatttctgcgtgtt
gccgacatcctggagagtaatgccaggcaggggcaggtggcgacggttctctctgccccg
gctaaaattaccaatcacctggtggcgatgattgaaaaaaccatcgggggtcaggatgca
ctggtgaacatcagcgacgctgagcagatctttgccagcctgctacagggcctggcggat
gcacagcctggctttccccacgcccaactgaaagccttcgttgagcaagagttcgctcag
attaaacacgttctgcatggtatcagcctgttggggcagtgcccggacagcatcaacgcg
gcgctgatctgccgtggtgaaaaactctctatcgccattatggcgggtctgctggaagcc
cgtggtcataacgtcacggtgatcgatcccgtcgaaaaactgctcgctgttggccattac
ctcgaatctaccgtagatattgccgaatctacccgtcgcattgcggcaggcaaaattcct
gctgaccatatgatcctgatggcgggcttcaccgccgggaatgaaaaaggggagctggtg
gtgctgggccgtaacggttccgactactccgccgccgtgctggctgcctgcctgcgggcc
gactgttgtgagatctggactgacgtcgacggcgtgtatacttgcgacccccggcaggtg
cccgatgcccgcctgctgaagtcgatgtcttatcaggaggcgatggagctctcctacttt
ggcgccaaagtgcttcaccctcgtactatcgcccctatcgcccagttccagatcccctgc
ctgattaaaaacaccggtaatccacaggcgccaggcacgctgattggcgccagcagcaat
gaagatggtctgccggtaaaaggtatctccaacctcaataatatggcgatgttcagcgtc
tccgggccaggcatgaaagggatggttggcatggcggcgcgcgtgtttgcggccatgtcg
cgcaacggcatctcggtggtgttaatcacccagtcctcctcggaatacagcatcagcttc
tgcgtacaccaggccgactgcctgcgtgcgcgccgggcgctggaagaggaattttacctg
gagctgaaagaggagctgctggagccgctctccatacaggaacgcctggccgttatctcg
gtggtgggcgacggtatgcgcaccctgcgcggcatctccgcgaagttctttgcggcgctg
gcgcgggcaaacatcaatattgttgccattgcccagggctcctcagagcgctccatctcc
gtggtggtgaataacgacgatgcgaccaccggcgtgcgcgttacccatcagatgctgttt
aacaccgatcaggtaatcgaggtgttcctgattggcgtcggcggtgtcggcggtgcgtta
ctggcgcagctgaagcgccagcaggagtggctgaagaaaaagcatatcgatctgcgcgtc
tgcggcattgcgaactccaaagcgttgctgaccaacgttcacgggctgaacctcgagaac
tggcaggctgagctggcggaggcgaaagagccgtttaatctgggccgcctgatccgtctg
gtgaaggagtatcatctgctgaacccggtgattgtcgactgtacctcccaccaggcggtg
gccgatcagtatgccgacttcctgcgcgaaggtttccacgtggtgacgccaaacaaaaag
gccaacacctcgtcgatggattactaccatcagatgcgtcacgcggcggcgaaatcccgt
cgtaagttcctctacgacaccaacgtcggcgccgggctgccggttatcgaaaacctgcaa
aacctgctcaatgccggggatgaactgcagcgtttctccggcattctgtcgggctcgctc
tcctttatctttggcaagctggatgaaggcatgagcctgtcggaagcgaccaaaatggcg
cgtgagctgggctacaccgagcccgatccgcgtgacgatctctccggcatggatgtggcg
cgcaagctgctgatcctcgcccgcgaaacgggacgtgagctggagctgtcggatatcgtc
attgaaccggttctgccggagagttttgaccactctggcgatgtcgccacctttatggcg
aatctgccgcagctggatgacgctttcgcctcccgggtcgcaaaagcccgtgatgaaggc
aaggtattgcgctatgttggcaacattgaagaagatggcgtctgccgtgtcaaagtggcg
gcggtcgacggtaacgatccgctgttcaaagtgaaaaacggcgaaaacgccctcgcgttt
tacagccactattatcagccactgccgttggtccttcgcggctatggcgcggggaatgat
gtgacggcggcgggcgtgtttgccgatctgctgcgtaccctgtcatggaagttaggagtt
taa
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