KEGG   Leclercia sp. W17: DVA44_15515
Entry
DVA44_15515       CDS       T05987                                 
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
lee  Leclercia sp. W17
Pathway
lee00290  Valine, leucine and isoleucine biosynthesis
lee00620  Pyruvate metabolism
lee01100  Metabolic pathways
lee01110  Biosynthesis of secondary metabolites
lee01210  2-Oxocarboxylic acid metabolism
lee01230  Biosynthesis of amino acids
Module
lee_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:lee00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    DVA44_15515 (leuA)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    DVA44_15515 (leuA)
Enzymes [BR:lee01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     DVA44_15515 (leuA)
SSDB
Motif
Pfam: HMGL-like IPMS_D2 LeuA_dimer
Other DBs
NCBI-ProteinID: AXF65407
LinkDB
Position
3107698..3109374
AA seq 558 aa
MLRNPSQKYVAYAPISLPDRQWPDKILTHAPRWLSTDLRDGNQALAEPMDIPRKLRFWEQ
LLKCGFKEIEVAFPSASETDFQFVRQLIEEQRIPDDVTIQVLTQARSDLIERTFASLDGA
KRATVHLYNATAPLFRQLVFRQSQEEIVQLAVSATRQIRALCEANPQTRWTYEYSPETFC
FTEPEFALHICEAVADVWEPSAERPMIVNLPATVEVNTPNVYADQIEYFCRHFSRRSEVC
ISVHPHNDRGSGVASAELALLAGADRVEGCLFGNGERTGNVCLVTLAMNLYSQGVSPQLD
FSDMKQVVELVEQCNQLPVHPRHPYAGKLAFTAFSGSHQDAIKKGFHAREQSASPRWEMP
YLPVDPEDIGCSYEAVIRVNSQSGKSGAAWMLEQNHGLALPRALQQDFSRHVQAHTDREG
TEMTLSALWQLYRELYGPHQHAPRQLLDYRTESQADGGLLLWARVQTADGIVILEGNGNG
LLSAAASAIKASFHLAFAIEDYHEHTLGRCSESRSAAYIRCSFKQCASRWGTGIDNDVSR
ASLQALLNALPESASGGK
NT seq 1677 nt   +upstreamnt  +downstreamnt
atgttgcgcaacccttcgcaaaagtacgtggcctatgcccccatttcgttacccgaccgc
cagtggccggataagatcctgacccacgccccgcgctggctatcaaccgacctgcgcgac
ggcaaccaggcgctggcggaaccgatggatatcccccgcaagctgcgcttctgggagcag
ctgctcaaatgcggcttcaaggagattgaggtggcgttcccctccgcctcagagacagat
tttcaatttgtccgccagctgattgaggagcagcgcatcccggatgatgtcaccattcag
gtgcttacccaggcccgcagcgatctgattgagcgcaccttcgcttccctcgatggggca
aaacgcgccacggtgcatctctataacgccaccgcgccgctgttccgccagttggtcttt
cgccagagccaggaggagattgtgcagctggcggtcagcgccacgcggcagatacgtgcg
ctgtgcgaggccaacccgcagacgcgctggacctatgagtattcgccggaaaccttctgc
tttaccgaaccggagtttgccctgcacatctgcgaggcggtggcggatgtctgggaaccc
tctgccgaacggccgatgatcgtcaacctgcctgctacggtggaggtcaacacccccaac
gtctatgccgatcagatcgagtatttctgccgccacttctcccgtcggagcgaggtctgc
atcagcgtccatccccataacgatcgcggcagcggcgttgccagcgccgagctcgccctg
ctggcgggtgccgaccgggtggaaggttgcctgttcggtaacggggagcgcaccgggaac
gtctgtctggtgaccctggcgatgaacctctacagccagggggtctcgccgcagctcgat
ttcagcgatatgaagcaggtggtggaacttgtggagcagtgcaaccaactgccggtgcat
ccccgccatccttacgccggtaagctggcttttactgccttctctggctcacatcaggac
gccatcaaaaaggggtttcacgcccgggaacagtccgcctccccgcgctgggagatgccc
tatctcccggtggacccggaagatatcggctgtagttatgaggcggtgatccgcgttaac
agccagtccggcaaaagcggcgcggcgtggatgctggagcaaaatcatggcctggcgctg
ccccgggccctgcaacaggactttagccgccacgttcaggcgcacaccgatcgggaaggt
accgagatgacgctgagtgcgttgtggcagctttatcgcgagctgtatgggccacatcag
cacgccccacggcagctgctggattaccgcaccgaaagccaggccgacggcgggctgctg
ctgtgggcccgcgtccagaccgccgacgggattgtgatcctggaggggaacggtaacggc
ctgctctctgccgccgccagcgcgataaaagccagttttcatctggccttcgccattgag
gattatcacgagcataccctcgggaggtgcagcgaaagccgctcagcggcctatatccgc
tgcagctttaagcagtgcgccagccgctggggaacgggcatcgacaacgatgtttcccgg
gcgtcgcttcaggctttgctgaatgcgttgccggagagcgcctcaggcgggaagtag

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