Leifsonia sp. ZF2019: IT072_12445
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Entry
IT072_12445 CDS
T10186
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
leiz Leifsonia sp. ZF2019
Pathway
leiz00300
Lysine biosynthesis
leiz00550
Peptidoglycan biosynthesis
leiz01100
Metabolic pathways
leiz01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
leiz00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
IT072_12445
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
IT072_12445
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
IT072_12445
Enzymes [BR:
leiz01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
IT072_12445
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
UAJ81562
UniProt:
A0A9E7BQ92
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All DBs
Position
complement(2560387..2561814)
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AA seq
475 aa
AA seq
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MIALTLAEVAAATRGTLLLDGAAVAGVPATAETVVDGLSTTDSREVVPGTIFFAKPGEFT
DGHLFAPQAAEAGAALVVVDHPLDLAVPQLLVEDTVVALGDLATEVIARVRALGRLKIVG
VTGSNGKTTTKNLLREILEQVGPTIAPRASFNNEVGAPVTMLEVTEETQFLVAEMGASGI
GEIARLVRMARPDIGIVLKVGLAHAGEFGGIERTLAAKTEMVSDLLESDVAVLNLDDPRV
ASMADKTVARVLWFGLDDRAAVRATGIVSSAAGTSFTLHLPDGSEREVHFRVLGEHHVMN
ALAAAAAAHTLDVGIDAIVTGLQAVTRAERWRMEVMGGARGVTVINDAYNASPDSMSAAL
KTLAQIAEPGARTVAVLGEMSELGEFSGEEHDRIGLLAVRLGIGQLVVVGPSARRMHISA
INEGSWDGESLYFDTQDDAYAHLAGALREGDTVLVKSSNSAGLRFLGDRLGELFS
NT seq
1428 nt
NT seq
+upstream
nt +downstream
nt
atgatcgcgctcaccctcgccgaggtcgccgcggcgactcgcggcaccctgctgctcgac
ggcgccgccgtcgcgggcgtccccgccactgccgagaccgtggtcgacggcctgtcgacc
accgactcgcgcgaggtcgtccccggaacgatcttcttcgccaagccgggcgagttcacc
gacggacacctgttcgctccgcaggccgcggaggcgggagccgcgctcgtcgtcgtggac
cacccgctcgacctcgcggtgccgcaactgctcgtcgaggacaccgtcgtcgcgctcggc
gacctcgccaccgaggtgatcgcccgggtgcgcgccctcggtcgcctgaagatcgtcggc
gtcaccggctcgaacggcaagacaaccaccaagaacctcctccgcgagatcctggagcag
gtcggtccgaccatcgccccgcgcgcctcgttcaacaacgaggtcggggcgccggtcacg
atgctcgaggtcacggaggagacgcagttcctcgtcgccgagatgggcgcgagcggcatc
ggcgagatcgcccgtctcgtgcgcatggcgcgccccgacatcgggatcgtcctcaaagtc
ggcctcgcgcacgccggggagttcggcggcatcgagcggacgctcgcggcgaagaccgag
atggtcagcgacctgctcgagtccgacgtcgcggtgctcaacctcgacgatccgcgcgtc
gcctccatggccgacaagacggtcgcccgcgtactctggttcggtttggatgaccgggcg
gccgtgcgcgcgaccggcatcgtctcgagcgccgccggcacatcgttcaccctccacctc
ccggacggctccgagcgcgaggtgcacttccgcgtgctcggcgagcatcacgtcatgaac
gcgctcgcggcagccgcggcggcgcacaccctcgacgtgggcatcgacgcgatcgtcacc
ggtctgcaggcggtgacgcgcgccgagcgctggcgcatggaggtcatgggcggtgcgcgc
ggcgtcaccgtcatcaacgacgcctacaacgccagccccgactccatgtccgccgccctc
aagacgctcgcgcagatcgccgagcccggggcgcgcacggtggccgtgctcggcgagatg
agcgagctgggcgagttctcgggggaggagcacgaccgcatcggtctgctggccgtgcgg
ctcggcatcggccagctcgtcgtggtcgggccctccgcccggcggatgcacatctcggcg
atcaacgaaggctcctgggacggcgagtccctctacttcgacacgcaggacgacgcgtac
gcccacctggccggcgcgctccgcgagggcgacaccgtgctcgtgaagtcctccaactcc
gcggggctgcgcttcctcggcgaccgactgggagaattgttctcgtga
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