Lysobacter enzymogenes M497-1: LEN_1060
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Entry
LEN_1060 CDS
T04598
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
lem
Lysobacter enzymogenes M497-1
Pathway
lem00300
Lysine biosynthesis
lem00550
Peptidoglycan biosynthesis
lem01100
Metabolic pathways
lem01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
lem00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
LEN_1060 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
LEN_1060 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
LEN_1060 (murF)
Enzymes [BR:
lem01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
LEN_1060 (murF)
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
BAV96547
UniProt:
A0AAU9ACG4
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All DBs
Position
1204777..1206162
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AA seq
461 aa
AA seq
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MKRLSLSEIARLTGGRLHGADADVDVVCTDTRVLPAQGAALFVALKGERFDGHDHVAGLA
HTAVAAALVAREIDAPIAQVIVADTQQALADLAAGVQAQRAGNTVVAITGSNGKTSVKAL
TTAILERAGNTYATPGNRNNEIGLPLAVLDAPEDARFSIYEMGAGKPGDIAYLVRVARPQ
VSLVNNIAPAHLERMGSLLGIADTKAAIYDALPESGAAAINADDAFAPYFEQRAAGRRLI
RFGLDASAEVTASNVRVGPEGSTFALVTPLGRVEIALRMVGRHNVRNALAAASLALGAGV
SLQHIADGLNVAQPVDGRLITHRLDNGAVLIDDSYNANPGSTAAAIDTLAEMGGENWLVL
GAMREIGNEEIAMHAEIGRRAKAAGLRRLYALGELPAAAAAAFGDGAQVFASHGELAAAL
SAELAAGVRVLVKGSHSSAMDKIVTALLSAHRPGEGTTHVA
NT seq
1386 nt
NT seq
+upstream
nt +downstream
nt
gtgaagcgcttgagcctgagcgagatcgcgcgcctgaccggcggccgcctgcatggcgcc
gacgcggacgtggacgtcgtgtgcaccgacacccgcgtgctgccggcgcagggcgcggcg
ctgttcgtcgcgctcaagggcgagcggttcgacggccacgaccacgtcgccgggctggcc
cacaccgcggtcgccgcggcgctggtggcgcgcgaaatcgacgcgccgatcgcccaggtg
atcgtcgccgacacccagcaggcactggccgacctcgccgccggcgtgcaggcgcagcgc
gccggcaacaccgtggtggcgatcaccggcagcaacggcaagaccagcgtcaaggcgctg
accacggcgatcctggagcgcgccggcaacacctacgcgaccccgggcaaccgcaacaac
gagatcggcctgccgctggcggtgctcgacgcgccggaagacgcgcgcttctcgatctat
gaaatgggcgcgggcaagccgggcgacatcgcttatctggtgcgcgtggcccggccgcag
gtgtcgctggtcaacaacatcgccccggcgcacctggagcgcatgggcagcctgctcggc
atcgccgacaccaaggcggcgatctacgacgcgctgccggaaagcggtgcggcggcgatc
aacgccgacgatgcgttcgcgccgtacttcgagcagcgcgcggccgggcggcggttgatc
cgcttcgggctggatgccagcgccgaggtgacggcttcgaacgttcgcgtcggacctgaa
ggttctacgttcgccctcgttactccgttgggacgagtggagatcgcgctgaggatggtt
ggccgccacaacgtgcgcaacgccctggccgccgcgtcgctggcgctgggcgcgggcgtg
tcgctgcagcacatcgccgacggcctcaacgtcgcgcagccggtcgacggccgcctgatc
acccaccgcctggacaacggtgcggtgctgatcgacgacagctacaacgccaatcccggt
tcgaccgcggcggccatcgacacgctggcggaaatgggcggcgaaaactggctggtgctc
ggcgcgatgcgcgagatcggcaacgaagaaatcgccatgcacgccgagatcggccgccgc
gccaaggccgccggcctgcgccggctgtatgcgctgggcgagctgccggccgcggccgcg
gccgcgttcggcgacggcgcgcaggtgttcgccagccacggcgagctggccgcggcgttg
agcgcggaactcgccgccggcgtgcgggtgttggtgaaaggttcgcacagcagtgcgatg
gacaagatcgtgacggcgttgttgtcggcacaccggccgggggagggcacgacgcatgtt
gcttga
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