Lysobacter enzymogenes M497-1: LEN_4118
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Entry
LEN_4118 CDS
T04598
Symbol
lysC
Name
(GenBank) bifunctional aspartokinase I/homeserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
lem
Lysobacter enzymogenes M497-1
Pathway
lem00260
Glycine, serine and threonine metabolism
lem00261
Monobactam biosynthesis
lem00270
Cysteine and methionine metabolism
lem00300
Lysine biosynthesis
lem01100
Metabolic pathways
lem01110
Biosynthesis of secondary metabolites
lem01120
Microbial metabolism in diverse environments
lem01230
Biosynthesis of amino acids
Module
lem_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
lem_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
lem_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
lem00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
LEN_4118 (lysC)
00270 Cysteine and methionine metabolism
LEN_4118 (lysC)
00300 Lysine biosynthesis
LEN_4118 (lysC)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
LEN_4118 (lysC)
Enzymes [BR:
lem01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
LEN_4118 (lysC)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
LEN_4118 (lysC)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
ACT_9
AA_kinase
NAD_binding_3
ACT_7
ACT
F420_oxidored
Motif
Other DBs
NCBI-ProteinID:
BAV99605
UniProt:
A0AAU9AYW8
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All DBs
Position
5161288..5163849
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AA seq
853 aa
AA seq
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MSSAPPQAAFDAQPDAAAGEDPLADAAAAHAAAAGPPARHAHKFGGSSLADPDRYRVAVG
LLDDGARERIAVVSAMQGVTDALVAIVDARLGGQDWKPAWTTLRKRHLDTALSLDPHRRH
GALEALEAEFVQLRDALESLHSRDEKTPQAIAGLGEVWSSYLIHAALGGDPAGWARLDAR
EVLVVHPSEMGMAVDWAQSRDNLAAWRKRNAAANVVVTGFVARDGYGYATTLGRNGSDYS
AAIFANLFDADALTIWTDVDGVLSADPRLVPDAVCLPSMSYAEACELAYFGAKVLHPQTM
APVQQRGIPLRIRNTRNPHSPGTLISLRAQPGQAPVKGLSLVHDLAVLELVGNGLVGVPG
AAERLFGALRAAGVSVTMISQGSSEHSICCVVRAAEAERGRDAIVAAFAEAMADGQAQHV
QVTPDICVLAAVGDGMVGQPGVAAQLFDGLAKARVNLRAIAQGAGERNISVAIAARDATR
ALRAAHSAFWLSPQCISIGVIGPGKVGRALLAQLAAAQPRFQRESRPQRRLDLRLRALAD
SRRMRLAPRALEFDDAHALEAESEALDLKRFAAHVRAEHIPHALIVDCSGSDAVAARYPE
WLAAGIHVVTPSKHAGAGPLARFEAIREAARHGGQFRYEATVGAGLPVIQTLRSLLDTGD
ELTEVEGILSGTLAWLFNRYDGRTPFSQLVREAHELGYTEPDPRDDLSGTDVARKLVILA
REAGRPLSLEQIEVESLVPESLRSVSKEEFFARLDELDAPLQQRFDAARAAGLSLRYLAR
LDRDGRASVGVVTPQPGHAALHGALTDNLIQFRTRRYADNPLVVQGPGAGPDVTAAGVFG
DLLTIAQTLGARA
NT seq
2562 nt
NT seq
+upstream
nt +downstream
nt
atgtcgtccgccccaccccaagccgctttcgatgcccagcccgatgcggccgcgggcgaa
gatcctcttgccgacgccgctgccgcgcacgcggccgcagccggcccgcccgcgcgccac
gcgcacaaattcggcggcagcagcctcgccgatcccgaccgctaccgcgtcgcggtcggc
ctgctcgacgacggcgcgcgcgagcgcatcgcggtggtctcggcgatgcagggcgtcacc
gacgcgctggtcgcgatcgtcgacgccagattgggcggccaggactggaagccggcctgg
accacgctgcgcaagcgccacctcgacaccgcgctgtcgctggacccgcaccgccgccac
ggcgcgctggaagcgctggaagccgagttcgtgcagttgcgcgacgccctggagtccctg
cattcgcgcgacgaaaaaaccccgcaggcgatcgccggcctgggcgaggtgtggtcgtcc
tatctgatccacgccgcgctcggcggcgatccggccggctgggcgcggctggacgcgcgc
gaggtgctggtggtgcaccccagcgaaatgggcatggcggtggactgggcgcaaagccgc
gacaacctcgccgcgtggcgaaaacgcaacgccgcggccaacgtggtggtcaccggcttc
gtcgcccgcgacggctacggctacgccaccacgctcggccgcaacggcagcgattactcc
gcggcgatcttcgccaacctgttcgacgccgacgcgctgaccatttggaccgacgtcgac
ggcgtgctctcggccgatccgcggctggtgcccgatgcggtctgcctgccttcgatgtcg
tatgccgaagcctgcgaactggcttatttcggggcgaaagtattgcatccgcagaccatg
gcgccggtgcagcagcgcggcatcccgctgcgcatccgcaacacccgcaacccgcactcg
cccggcacgctgatcagcctgcgcgcgcagcccgggcaggcgccggtgaaggggctcagc
ctggtccacgacctggcggtgctggagttggtcggcaacggcctggtcggcgtacccggc
gcggccgagcgattgttcggcgcgctgcgcgcggccggcgtctcggtgacgatgatttcg
caaggctcctccgaacattcgatctgctgcgtggtgcgcgcggccgaggccgaacgcggc
cgcgacgcgatcgtcgccgccttcgccgaagcgatggccgacggccaggcgcagcacgtg
caggtcaccccggacatctgcgtgctggccgcggtcggcgacggcatggtcggacagccc
ggcgtggccgcgcagttgttcgacggcctggccaaggcgcgggtcaacctgcgcgccatc
gcccagggcgcgggcgagcgcaacatctcggtggcgatcgccgcgcgcgacgccacccgc
gcgctgcgcgcggcgcattcggcgttctggctgtcgccgcagtgcatttccatcggcgtg
atcggcccgggcaaggtcggccgcgcgctgctcgcgcagctggccgccgcgcaaccgcgt
ttccagcgcgaatcgcgcccgcagcggcgcctggacctgcgcctgcgcgcgctcgccgac
agccggcgcatgcgtctggcgccgcgcgcgctcgagttcgacgacgctcacgcgctcgag
gccgagtccgaagcgctggacctgaagcgcttcgccgcgcacgtgcgcgccgagcacatc
ccgcacgcgctgatcgtcgattgcagcggctccgacgcggtcgccgcgcgctatcccgaa
tggctcgccgccggcatccacgtggtcaccccgagcaagcacgccggcgccggcccgctg
gcgcgcttcgaggcgatccgcgaagccgcgcgccacggcggccagttccgctacgaggcc
acggtcggcgccggcctgccggtgatccagaccctgcgctcgctgctcgacaccggcgac
gagctgaccgaggtcgaaggcatcctgtcgggcaccctggcctggctgttcaaccgctac
gacggccgcacgccgttctcgcaactggtgcgcgaggcgcacgagctgggctacaccgag
ccggacccgcgcgacgacctgtccggcaccgacgtcgcgcgcaagctggtgatcctggcg
cgcgaagccgggcggccgttgtcgctggagcagatcgaagtcgagagcctggtgccggag
tcgttgcgcagcgtgtcgaaggaagagttcttcgcccgcctggacgagctcgacgcgccg
ctgcagcagcgcttcgacgccgcgcgcgcggccgggctgagcctgcgctatctcgcgcgc
ctcgaccgcgacggccgcgccagcgtcggcgtggtcaccccgcagccgggccacgcggcc
ttgcacggcgcgctcaccgacaacctgatccagttccgcacgcgccgttacgccgataat
ccgctggtggtgcaaggcccgggcgccggcccggacgtcaccgccgccggcgtgttcggc
gatctgctgaccatcgcccagaccctcggagcccgcgcatga
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