Leucoraja erinaceus (little skate): 129700332 Help Entry 129700332         CDS       T09122                                  Symbol ryr3 Name (RefSeq) ryanodine receptor 3 isoform X1   KO K04963   ryanodine receptor 3 Organism leri  Leucoraja erinaceus (little skate) Pathway leri04020   Calcium signaling pathway leri04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:leri00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     129700332 (ryr3)    04020 Calcium signaling pathway     129700332 (ryr3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:leri04040]     129700332 (ryr3) Ion channels [BR:leri04040]  Voltage-gated cation channels   Ryanodine receptor    129700332 (ryr3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR RR_TM4-6 SPRY Ins145_P3_rec MIR RIH_assoc EF-hand_7 EF-hand_1 EF-hand_6 EF-hand_5 Motif Other DBs NCBI-GeneID:  129700332 NCBI-ProteinID:  XP_055496701 LinkDB All DBs Position 9:46519546..46844028 Genome browser AA seq 4729 aa AA seqDB search MYGSVYANTEISSLLTVEGRRVQRVSGAGSSKTMAEGGEGEDDIQFLRTDDEVVLQSVAT IKKEQRKFCLSTEGFGSRLCFLEPTSEAKYVPPDLSICVFVLEQSLSVRALQEMLTSTSE KNNEGGSVKRCHISAKKTKSLRAAQGGGHRTLLYGHAILLRHTYSGMYLSCLTTTRSLTD KLAFDVGLQEDSTGEACWWTIHPASKQRSEGEKVRIGDDLILVSVSSERYLHLSISNGTI QADASFIQTLWNVHPISSGSNVAEGFLNGGHVLRIFHGHDECLTIPFADQREEVHVTVNY ESGEAGIYARSLWRVEPLRISWSGSHVKWGQSFRLRHLTTGLYLGLVQDQGLVLLDPTKS DIKATSFCFRTSKEKLDLPPKRDTDGMGVPEIKYGDSICIIQHVATGLWLTYHAPDAKSA RLGPLKRKVILHQEGHMDDGIILQRCRKEEARASRIIRKTTILFNQFIRGLDCLGKSGLI KLPIKEVLEALQDLIIYFHPPEEDLKHEDKQYKLRSLRNRQNLFKEEAMLRLVLNCIDRL NVYHSAAHFSELAGEEVGEAWKDILNLLYELLAALIRGNRSNCAKFSKNLDWLVSKLDRL ESSSGILEVLHCILIESPEALNVIKECHIKSIISLLDKHGRNHKVLDLLCSLCVCNGVAI RVNQNLICDNLLPRRDLLLQTRMVNNVASIRPNIFLGTSEGSAQYKKWYYELAVDHVNPF LTANPIHLRVGWASAKGYAPYPGGGEGWGGNGVGDDLYSYGFDGLHLWSGRVSRSVSSPN QHILNGDDVVSCCLDLGIPSISFRINGQPVQGMFESFNTDGLFFPVVSFSAGAKVRFLIG GHHGDFRFLPPPGYAPCYEALLPKEKLRLEPIKEYKRDYDGVRDLIGTPCHLSQASFIPK PVDTCQIVLPSHLEKVQSKLAENIHELWATNKIELGWTYGKVRDDNKRQHPCLVNFDKLP EQERNYNLQMSLETLKTLLAFGCHVVHSKPKSEEDFQRMKLPKNYMMSNGYKPAPLDLSN VKLHTAQEVLVDKLAENAHDVWAKDRIRQGWTYGIQQDIKNKRNPRLVPYSFLDERTKKS NRDSLREAIRTLIGYGYNIEPSDQEITDETVEKVTVDKLRFFRVEKTYAVKTGKWYFEFE AVTAGEMRVGWARPTCKPDMELGSDGNAFVFNGYKAQFWHQGSVYFGHTWQPGDVVGCMI DMNDKSMIFTLNGELLITNSGSELAFTDFETEDGLIPICCLGLSQIGRMNFGKDATTFKY YTMCGLQEGFEPFSVNMNRDVAMWFSKRLPQFVPVPKNHNHIEVTRIDGTVDSPPCLKLS HKTFGTQNCITEMTYYRLSMPVEFYSTYKHDSIPHIADDDGAQTADTLSGKTKSRSARLS RDLPGDRAEQEVITKSSTYYYAVRIFAGQDPSFMWIGWVTPDYHYHSKSFDLNKHRTVTI TLGDDKGRVHESVKRSNCYMIWGGDLASSSKGSSGGRADLVIGCLVDLAIGRLSFTANGK DLSIHYQVEPSTKLFPAVFMQATSPNLFQFELGKLKNAMPLSAAIFKSEEENPIPQCPPR LDIQMITPVMWSRMPNDFLHVETARISDHHGWVLQCIEPLQMMALHIPEENRSIDILELI ENQELMKFHFHTLKLYCALCAVGNNRIAHALCSHIDQAQLIFTTEDKYLPGLLRSGFYDL LLSMHLESAKEARLIMNNEFIIPVTDETRSITLFPKNSRSYGCPGVGLSTCLRPRLNFSS PCFVSTIEDRRPYSPKLPFDILKVTAIEMLTEAVTVGGPHIRDPVGGSVQFHLVPILKLI KTMLITGMFDDNDVQKILLLIDSDLFGEHQEEMVDEGKLEKEIDVKNEEKAIEAGEVATQ ASPPPLKGLLEKSLPESVKLQMCELLHYFCDCELRHRVEAIVSFADKFVVKLQRNQRFRY EELMLAFNMSAALTAKKTKEFRSPPQEQINMLLNFRNDDDSTCPEDMREELCDFHDDLQT HCGIPFEDEQTEEKDESLMGKLLYLVHKIKGKPKKVEEPPSEKEVKKPANLSQLISQTIV HWSQESYIQDAELIKTMFSLLRRQYDAIGELLKAMRKAYTISAASVQETVSLLVSLGQIR SLLSVRMGKQEETLMIRGLGDIINNKVFYQHPNLMRVLGMHETVMDIMVSVLGGNKSQVI AFPEMVASCCRFLCYFCRISRQNQKAMFDHLSYLLENSSVGLASPSMRGSTPLDVAAASV MDNNELSLELQEPDLEKVVTYLAACGLQSCPVLVAKGYPDIGWNPIEGERYLLFLRFAVF VNGESVEENSSVVVKLLIRRPECFGPALRGEGGHGLLAAMKEAIETSEDPCRDLPPVEAG KNGAEEDDEEVVHMGNSIMSFYSALIDLLGRCAPEMHLIQAGKGEAIRIRAILRSLVPTE DLVGIISIPLKLPVFNPDGSISEPAMSASFCPDHKAPMVLFLDRVYGIEDQSFLLNLLEI AFLPDLRASASLESASLNTTEIALALNRYVCSTVLPLLTRCAPLFAETEHFAPLIDTTLH TIYRLSKGRCLTKAQRESIEECLLSICRYLHPSMLQPLLRRFVFDVPLLNEYCKMPLKLL SKHYVQCWKYYCLASGWGNYGSASDEELHLTKKLFWGVLDALSTKKYQPDLFKMALACLS ALGGALSPDYVDSSFSVVVDRQTSVDDKGNFEPNPINTSNTSIPEKLEYIVNKYADHLHE KWACEKIQNEWTYSDTINENMKTHPLLRPYKTLTEREKELYRWPTKESFRIMLALNWNIE RTKESEAMMQHLESEKQRKASQSSGGYSPVPADLSNALLSRENQAMAELLAENYYNIWAK KRKIELESKGGGSQTSLMPYDTLTAKEKARDRDKAHELFKFLQVNGYAISRGLKDMELDS SSFEKRFAYKFLVKVLKCVDSAQEFIAHLEAIVSSGKADKSHEREIKFFAKILLPLIDEY FKNHYMYFLSSPTKSLSSSGYASNKEKEMLASIFCKLAALVRHRISLFGTDSGTIVNCLH ILARTLDPRTVMKSGSELVKAGIRSFFENAAEDLEKTLENLKLGKFTHSRSQLKGVTQNI NYTTIVLLPVLTSLFDHIGQHQFGTNIILDDVQVACYRILCSLLALGTGKNAYVERQRPV LGECLATLAAAMPVAFLEPSINVHNVHSVFNTKSPRERIILGLPDTVEEVCPEVPHLDAL IKEINETAESGARYTEMPHIIEVILPMLCNYLSYWWERGPENKPSGDCCTIVTSEHLSAI LGNVLKILNNNLGIDDASWMKRLAVYAQPIISKAKPDLLRNQFIPTLEKLKKKAIKVVQE EEQMKAECKVDFQETELLILDEFAVLCRDLYSFYPILIRFVDYNRARWLKEPNADADELF RMVAEIFILWCKSHNFKREEQNFVIQNEINNMAFLTADNKSKMSKAEGQSQERKTIQRRG DYYSVQTSLIVAAVKKLLPIGLNMCTAGDQELISLAKQRYNLKDTDEEVKEFLANNLHLQ DKFDDPAVRWQLNLYKDIAKPEERMDPQKIVERVQKISAAVFHLEQVEQPLRSKKTGWQK LLSKQRKRAVVACFRMAPLYNLPRHKINIYFLNAYQRLWLEKLYKNTDFENLIVCLTKSA TKSEEEEEEFDKTPDPLHQLILHFSRTALTERSAIEEDPLYLAYADMMAKSCHVDDDDEE DEEKEKTFEEKEMEKQMTLYQQARLHQRAAAEMVIQMISASKGALTPMVTTTLKLGISIL NGGNPDVQRIMLDYLKEKKESGFFRSLSGLMRSCSILDLNAFERQNKAEGLGMVTEDGTL IVRGHGDKVLQNDEFTRDLFRFLQLLCEGHNGDFQNYLRTQTGNTTTVNIIISTVDYLLR LQESISDFYWYYSGKVVMDEQGQRNFSKALAVAKQIFNSLTEYIQGPCIGNQQSLAHSRL WDAVVGFLHVFANMQMKLSQDSSQIELLKELLDLQQDMVVMLLSLLEGNVVNGTIGKQMV DTLVESSSNVEMILKFFDMFLKLKDMTTSDTFKDHDLDGKGVISKKEFQKALESQKKYAQ SEIEFLLSCVEADENDMFNYMEFIDRFHEPAKDIGFNVAVLLTNLSEHMPNDIRLKTFLQ PAQSVLTYFEPYLGRIEIMGAAKRIERVYFEISESSRTQWEKPQVKESKRQFIFDVVNEG GESEKMELFVNFCEDTIFEMQLASEISEPDAAERADDDEEESPPDEEDEEVAQPSNAFTA ACHNFKGALLNFFKIFTLRNIRRQYKTIKRMTTMELIMKIFSFFWMLFIGFVCFIFNIVQ GFFQIVWSAMFGGGLVEGAKSITVTDLLASMPDPTQLGIHGDVSESERSETPELGVVAEH QSIAQDEKSETEVMPDIFGTSMKKGGKAGDEHGGLGDVSEIIGAEGPLSIEKAISQKKKA EIEQKNKNESKTEFEKADTEDGEKMDKAKEEQPDESEEIEQKIKKRRRGQTKKEPEAFLV NFWEGLEIYQTKILNYLARNFYNLRLLALFVAFAINFILLFYKVTEPPADEEEADFSFWN DDKVDFYVLQETTGYMAPTLTFLALIHTIISMLCIIGYYILKVPLVVFKREKEIARTLEF DGLYITEQPSDDDIKGQWDRLVINTPSFPNNYWDKFVKRKVINKYGDLYGVERIGELLGV DKSSLDFSPIEEAPEREATLVSWLSSIDLKYHIWKLGVVFTDNSFLYLAWYTTMSILGHY NNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQVRTIKHKVWLMSYYFQS NT seq 14190 nt NT seq  +upstreamnt  +downstreamnt atgtatggatccgtctatgctaataccgagatcagcagcttgctgacagtagagggacga agggtccagcgtgtgagcggagccggctcttcaaaaaccatggctgaagggggtgaaggg gaagatgacattcagttccttagaactgatgacgaagttgtacttcagtccgttgccacc atcaagaaagaacaacgtaaattttgcttgtcaactgaaggatttggcagtcgtttgtgt tttctcgagcctacttcagaagctaagtatgttcctcctgacctttccatctgtgtgttt gtgctggagcagtcattgtctgtcagagccttgcaggagatgttgaccagtacaagtgaa aagaacaatgaagggggctctgtcaaaagatgtcacatcagtgccaagaagacaaaatct ctgagggcagctcaagggggtggacacagaacccttctttatggccatgctattcttctc cggcacacatatagtggaatgtatttgtcttgtttgacaacaacaagatctttgacagac aaactggcttttgatgttggtctgcaagaagattcaacaggtgaagcatgttggtggact atacatcctgcgtcaaaacaaagatctgaaggagaaaaagtacgaattggtgatgacctt attctggtcagtgtttcatcagagcgttacctgcacctttccatttccaatggcaccata caagcagatgcctccttcatacagacactgtggaatgtccatcccataagttcaggcagt aatgtagcagaagggtttctgaatggtggacatgttctgcgaatttttcatggtcatgat gagtgtttgaccatcccatttgccgaccagagggaggaagtacatgtaacagttaactat gaaagtggggaagcaggaatctatgctagatcactgtggcgtgtggaacctcttaggatc agttggagcggtagtcacgttaaatggggccagtctttccgtctgagacacctcacaacg ggtctgtatctgggtttagttcaggatcagggtttggtgctgctggatcccactaaatct gatatcaaagcaacatcattctgcttcagaacatcaaaggaaaaactggatttaccccca aaacgagatacagatggtatgggagtccctgaaatcaagtacggtgattcgatttgtatt attcaacatgtagctactggcctctggttaacatatcatgctccagatgccaaatcagca cgcctgggacctttgaagcggaaggtaatattacaccaagaaggacatatggatgatggt ataatcttgcaacgttgtcgaaaagaagaggcacgggcatctcgtattatacgaaaaaca acaatcttatttaatcagttcatcaggggtcttgattgtcttggtaaaagtggactcatc aaattacccataaaggaagttctggaagccttgcaagacctgatcatttacttccatcca ccagaggaggatttaaaacatgaagacaagcagtacaaattacgctcgctcagaaacaga cagaacttatttaaagaagaggcaatgctgagactggttctgaattgcattgatcgacta aatgtttaccacagtgcagcacatttttcagaacttgctggcgaagaagttggagaagca tggaaagatatcttgaatttgctctatgaactactagctgctctaatacgtggtaaccga agtaactgtgccaaattttcaaaaaacctagactggttggtcagtaaattagacagactg gaatcttcatcaggtatcctcgaagtactacattgcatcttgatcgaaagtcctgaagca ctaaatgtgattaaagaatgccacatcaaatctattatttcattactggataaacatgga cgcaatcacaaggtgctggacctgctatgctctctgtgtgtgtgcaatggtgttgctata cgagttaatcagaacctgatatgtgacaatctgctaccccgtcgtgatttacttctgcaa actcgcatggttaacaatgtagcaagcatcaggcccaacatattcctgggaactagtgaa ggttcagcgcagtacaagaaatggtattatgaactggccgttgatcatgtcaatcccttt ttgactgcgaatcctattcacttgcgtgttggttgggcatccgcaaagggttacgctccc tatcctggaggtggagagggatggggaggaaatggtgtgggtgatgatctttattcttat ggatttgatggacttcatttgtggtcaggtcgagtatcaaggtctgtgtcatcacctaat caacatatactgaatggcgatgatgtagttagttgttgcctggatttaggtattccaagt atttccttccgcattaatggacagccagtacaaggaatgtttgagagcttcaataccgat gggctgttcttcccggtggtcagcttttctgcgggtgccaaagtacgttttttgattggt ggtcatcatggagattttaggtttttgcctcctcctggatatgcaccctgctatgaggca ctactaccaaaggaaaaactgagattggaaccaatcaaagagtacaagcgagattatgat ggcgttcgagatttaataggaactccatgtcatctttcccaagcctccttcatcccaaaa ccagtagatacctgccagattgttttaccttcacaccttgagaaagtccagagcaaattg gccgaaaacattcatgaactttgggcaacaaacaagattgagcttggctggacatatggg aaggtacgagatgacaacaagagacagcacccttgtttggttaattttgataagctacca gaacaagagagaaactataatttacaaatgtcccttgaaactttaaagaccctcctggcc tttggttgtcacgttgttcacagtaaaccaaaatctgaggaagatttccaaagaatgaaa cttccaaaaaattacatgatgtcaaacggctataagcctgcaccgctggacctttcaaat gtcaagttacatacagcccaggaagtattggttgacaagctagcagaaaatgcacatgat gtctgggctaaagacagaattagacaagggtggacctatggaatccaacaggacatcaag aacaaaagaaaccctcgactagtgccgtatagttttctggatgagcgaaccaaaaaatca aatagagacagtttacgtgaagcaattcgcacattaattggatatggctacaacattgaa ccatcagaccaggaaattactgatgaaactgtggaaaaggttactgtcgacaaactccgt ttctttcgggtggagaagacctatgcagtaaagactggaaagtggtactttgagtttgag gcagtcactgcaggagaaatgcgagttggctgggcaaggccaacatgcaaacctgatatg gagctgggttctgacggaaatgcctttgttttcaatggctataaggctcagttctggcac caaggcagtgtttactttggccatacttggcagccaggtgatgtggttggttgcatgatt gatatgaatgacaaatcaatgatatttactctaaacggagaactcctcatcactaatagc ggctcagaactcgcctttaccgattttgaaactgaagatggtttaatcccaatttgttgt ctgggcttgtctcagataggtcgaatgaattttggaaaggatgcaaccactttcaagtat tatactatgtgtggtttacaagagggctttgagcctttttcagtaaacatgaaccgtgat gtagccatgtggttcagtaaacgcctacctcagtttgtccctgtaccaaaaaatcacaac catattgaggtaacaagaattgatggaactgtagacagtccaccctgtttaaaactgtct cataaaacctttggcactcaaaactgcattactgaaatgacatattaccgtttgagtatg cctgtagagttttattcaacgtataaacatgatagtattccacatattgctgatgatgat ggagctcagactgccgatacattgtcgggaaagactaaatcaaggagtgcaagattgagc cgtgatttacctggagatagagctgaacaagaagttattacgaagtcttcaacgtattac tacgcagtgagaatatttgcaggccaggatccgtcttttatgtggattggctgggtaact cctgactatcattaccacagcaaatcgtttgacttgaataaacaccggactgtaactatt actctgggtgatgacaaaggcagagttcatgaaagtgtcaagcgcagtaattgttatatg atttggggaggagatcttgccagcagttcaaagggatcaagcggtggccgtgctgaccta gtaattggttgtttggttgatcttgcaattggccggttatcattcacggcaaatggaaaa gatctcagtatacattaccaggttgagccaagcacaaagctatttcctgcagttttcatg caggccacaagtcctaatctcttccagtttgaacttggaaaattaaagaatgcaatgcct ctgtctgcagctatatttaaaagtgaagaggagaatcctattccacagtgccctcctcga cttgacatacagatgatcactcctgttatgtggagcagaatgcccaatgacttcctccat gtagagacagcaagaattagtgatcaccatggttgggttttacagtgtattgaaccattg cagatgatggcattgcatattccagaggagaataggtctatagatattcttgagctaatt gaaaatcaagagctgatgaagttccattttcatacattgaaattgtactgtgccctttgt gctgtgggcaataatcgtatagcccatgctctttgtagccacattgatcaagctcaacta atattcacaactgaggataaatatctcccaggacttctacgcagtggattctatgatctc ctcttaagtatgcacttagaatcagcaaaagaagccagattaattatgaacaatgaattc attattcctgtaactgatgaaaccaggagcataacattgtttccaaaaaatagtcggtct tatggatgtcccggtgttgggctcagcacctgcttacgacctcgattaaacttctcatca ccatgttttgtcagcaccattgaagatagacgcccatatagcccaaaattgccattcgat attcttaaggtcacagcaattgaaatgctcacagaggctgtgacagttggtgggccgcac atccgagatccagtgggtggaagtgtgcagtttcatctagttcctatactcaaacttatt aaaaccatgctgatcacaggcatgtttgatgataatgatgtccaaaaaattctgctactg atcgattctgacctatttggtgaacaccaagaagagatggtggatgaaggtaaactagag aaagagattgacgtgaaaaatgaagaaaaggcaatagaagctggagaagtagcaacacaa gcatctccgccgcctttaaagggactgctggaaaaaagtttgccagagtctgttaaactt cagatgtgtgaactgcttcactacttctgcgactgtgaactccgacatcgagtcgaagcc attgtttcttttgcagacaagtttgttgtaaaactgcaaaggaaccagaggttccggtat gaagagcttatgctggccttcaacatgtctgcagcattgactgccaagaagacgaaggag ttccggtcaccacctcaagagcagattaatatgttactgaacttcaggaatgatgatgat tccacttgccctgaagacatgcgtgaagaactgtgtgacttccatgatgaccttcaaacg cattgcggtattccatttgaagatgaacagacagaagaaaaagatgaatctctgatggga aagttgctttatttagtgcataaaatcaaagggaagccaaagaaagtggaagagccacca agtgaaaaagaagtaaaaaagcctgccaacctgtcacaattaatctcacagactattgtc cactggtcccaagagtcatacattcaggatgcagagctgattaaaactatgtttagcctt ttgcgccgacagtatgatgcaattggtgagctcctaaaagctatgcggaaagcatacacc atcagcgctgcatctgtccaggaaacggtcagtctgttggtctcgcttggacagattcga tccctcctgagtgttagaatgggaaaacaagaagaaacactaatgattcgcggattaggg gatatcataaataataaggtattctatcagcatccaaacctgatgagagtgctgggtatg catgagactgtcatggacatcatggtgagcgtccttggaggaaataaatcacaggtgatt gcgttccctgaaatggtggcgagctgctgtcgattcctttgctacttctgccgtatcagc cgccagaatcagaaggccatgtttgatcatctcagttacttgttggaaaatagcagtgtt ggactggcatcacccagcatgcgaggttctactcctctggatgtggcagcagcctctgta atggacaacaatgagctttctctggagttgcaggaacctgacttggaaaaggtggtgacc tatcttgctgcatgtggcttacagagctgcccagtgctagtggccaaaggttatcctgat attggctggaatcccattgaaggggaacgttatctactcttcttacgatttgcagttttt gtcaatggtgaaagtgttgaagaaaattcaagtgttgtcgtgaagttactaattcgccgt ccggagtgctttggcccagctctgagaggtgaaggaggacatggcttgctagcagcgatg aaagaggccattgaaacttcagaagatccttgccgtgatcttccacctgttgaagccggg aaaaatggtgctgaagaggatgatgaagaagttgtgcacatgggtaattctatcatgtcc ttctattcggctttgattgatcttctcggccgatgtgctccagagatgcatctaatccaa gcaggcaaaggtgaagctatccgaattcgagctattcttcgttccctcgtgccaactgag gacctggtgggcattattagtattccactgaaattgcctgtttttaatccagatggatct atttctgagccagcaatgtctgcaagtttctgtcctgaccacaaagcacccatggtactg tttctggatcgtgtttatggtattgaggaccaaagtttcctacttaatttgctggaaatc gcatttttacctgatttaagagcatcagcctcccttgaatcagcttccttaaatacaaca gagatagcacttgcacttaacagatatgtctgttcaacagtgcttccactactcacgaga tgtgcacctctttttgctgagacagagcactttgctcctttgatcgataccacgttgcac acaatctacagattatccaaaggacgttgtcttaccaaagcacagagagagtcgattgag gaatgtttgctgtccatatgccgatatcttcatccttccatgctgcagccacttctgcgt cgatttgtttttgatgttccccttcttaatgagtactgtaaaatgccattaaagcttctg agtaaacattatgtacaatgctggaaatactattgtttggcatctgggtggggcaattat ggaagtgcctctgatgaagagttacatcttaccaaaaaattattctggggagttttggat gcactctctacaaaaaaatatcagcccgatctctttaaaatggccttggcttgtctaagt gctttaggaggggccctgtcccccgactatgtagattccagcttttcagtcgtggtggac agacagacatcagtggatgacaaaggcaactttgaaccaaaccccatcaacacttccaat acttcaattccagagaagttagagtacattgtgaacaaatatgcagaccatctacatgag aagtgggcttgtgagaagattcaaaatgaatggacatatagtgatacaatcaatgaaaac atgaagactcatccattattgagaccctataaaaccttaacagaaagggaaaaggaattg tatcgttggccaaccaaggaatctttccggatcatgctggctttgaactggaacattgaa aggactaaagagagtgaggctatgatgcagcaccttgaaagtgagaaacagcgtaaggct tctcagagttcaggggggtactcccctgttccagctgacttgtcaaatgctttgctctcc agagagaatcaggcaatggcagagctcttggcagagaactattataatatttgggcaaaa aagaggaaaatcgaattagaaagcaaaggtggaggcagccaaacctctctgatgccttat gataccttgactgccaaggagaaggcccgggatcgtgataaggctcatgagttattcaag ttcctccaagtgaatggttatgcaatctctagaggcctgaaggacatggaattagattcc tcgtcttttgagaagcgatttgcttacaaattcctggtaaaagtgcttaaatgtgttgac tcggcacaggaatttatagcacatttagaggccattgttagtagtggtaaagcagacaaa tctcacgagcgagagataaagttttttgccaagattctacttccactgattgacgagtat ttcaagaatcactatatgtacttcttatcttctccgaccaagagtctcagcagcagtgga tatgcatccaacaaagaaaaggaaatgttggcaagtattttctgcaaacttgcagccctg gtcagacacaggatctcactctttggcactgattctggaacaatcgtgaactgtttacat atcttggcacgtacacttgaccccaggactgttatgaagtctggctcggagctggtaaaa gctggcatacgttcgttctttgaaaatgcagcagaagatctagaaaaaacactggaaaat ctgaaactggggaaattcacacattcaagatctcaactgaagggagtcacacagaatatc aattacacaaccatagttctactgcctgtactaacttcattatttgaccacattggtcag catcagtttggcactaacataatcttggatgatgtccaagtagcatgctacaggatccta tgcagcttgcttgccttaggaacagggaagaatgcctatgtggaaagacagcgacctgtc cttggagaatgtcttgccacacttgcagctgccatgccggtagctttccttgagccttct atcaacgtacacaatgtacactcagttttcaatacaaaatcgcctcgagaacgtatcatt ctaggtttacctgacacggtcgaggaagtgtgtccagaggtacctcatttagatgcatta ataaaggagatcaatgaaacagcagagtctggagcaagatacacagaaatgcctcatata attgaggtgattttgcccatgttgtgtaattatctgtcttattggtgggagcgaggccca gagaacaaacccagtggggactgctgcactatcgtcacctctgaacatcttagtgcaatt ttgggcaatgtcctgaaaatcttaaacaataacctgggcattgatgatgcttcctggatg aagagacttgcagtgtatgctcagccaattatcagcaaagctaagcctgatttgctgaga aaccaattcattccaacattggaaaagctgaaaaagaaagcaataaaggttgtacaggag gaagaacaaatgaaagcagagtgcaaggtggatttccaggaaactgagttactaatcctt gatgaatttgctgttctctgccgagatctctattccttctatccaatattgatccgcttt gtggattataacagggcaagatggttaaaggagccaaatgcagatgctgatgaactgttc cgtatggtggctgaaatttttatcttgtggtgtaaatcgcacaatttcaaacgagaggag cagaattttgtgattcagaatgaaatcaacaacatggctttcctgactgcagataataaa agcaagatgtctaaggcagaaggacaaagccaagaacggaaaacaattcagcgtagaggg gattattactcggtacagacatcactgattgtggctgctgttaaaaagttacttcctatt ggtttaaatatgtgcactgcgggagaccaagaattaatctcattggccaagcagagatac aatctgaaagacacagatgaagaagttaaagaattcctcgcaaataacttacatttacag gataagtttgatgacccagcagttcgatggcagcttaacttgtataaagatattgccaag cctgaagagagaatggatcctcagaagattgtggaacgtgtgcaaaagatttcagctgct gtttttcacttggaacaggtggagcagccactgcggtcaaagaagacaggctggcaaaag ctcttgtccaaacaacgcaaaagagcagtggttgcctgcttccggatggcaccactttat aacctgcccagacacaaaattaacatttacttcctgaacgcctatcaacgtctgtggctg gaaaagctatataagaacactgactttgagaatcttatcgtctgtttgacgaaatctgca actaagtcagaagaggaggaggaagaatttgacaagactcctgatccacttcatcagctt atactacacttcagtcgaactgccctcactgagcgaagtgcaattgaagaggacccctta taccttgcatatgcagacatgatggcaaaaagttgccatgttgatgatgatgatgaagaa gatgaagaaaaagaaaaaacttttgaagaaaaggaaatggagaaacaaatgacactctac cagcaagcaaggcttcaccagcgtgcagcagctgagatggttatacaaatgattagtgca agcaaaggtgcattaacacccatggtgaccacaacattaaagcttggtatctccattctg aatggtggtaaccctgatgtccagcggataatgttggactatttgaaggagaagaaagaa agtggttttttcaggagcctgtctggattgatgcgatcctgcagcatccttgacttgaat gcctttgagagacaaaacaaagcagaaggtctgggaatggtgactgaagatggaacactc attgttcgcggacatggtgacaaggtgttacagaatgatgaatttactcgggatttgttt cgtttcttgcaattgctgtgtgagggacataacggtgatttccagaattacctaagaact caaacaggaaacacaactacagtgaatatcattatcagcacagttgactatttgctgcgt cttcaggagtcaatcagtgatttctattggtattactcaggaaaagttgttatggatgaa caaggtcagcgcaatttctcaaaagcgttagctgtggctaaacaaatcttcaactcgctg acagagtatatccagggcccttgcattgggaaccagcagagtcttgcccacagcaggctc tgggatgcagtggttggtttcctgcatgtttttgctaatatgcaaatgaagctttctcag gattcaagccagattgagttgctcaaagagttattggatttacagcaagatatggtggtg atgctgttgtcattgttggaagggaatgttgtaaatggaaccattggcaaacagatggtg gacacactggttgaatcttccagcaatgtggaaatgatactcaagttctttgatatgttt cttaagttaaaggatatgactacgtctgataccttcaaagatcatgatctagatggtaaa ggagtgatttcaaagaaagaattccaaaaggctttggaaagtcagaagaaatatgcacaa tcagaaattgagttcctactatcttgtgttgaagcagacgaaaatgatatgtttaactat atggaatttattgaccgctttcatgaaccagccaaagacatcggttttaatgtagctgta ttactgactaatttatctgaacacatgcccaatgatatccgtctaaagacattcttgcag ccagctcaaagtgtcctcacatactttgagccctatttaggacgcattgagattatgggt gcagcaaagcgcatagaaagagtctactttgaaatcagcgaatcaagcagaacacagtgg gagaagcctcaggtcaaggaatccaagagacaatttatctttgacgttgtgaatgaaggc ggggaatcggaaaaaatggaactctttgtgaatttttgtgaggacaccatatttgaaatg cagttagcatctgaaatctctgaaccagatgcagctgagagagctgatgatgatgaagag gagtctcctccagatgaagaagatgaggaggtggctcagccctcaaatgcatttacggca gcgtgtcacaatttcaaaggtgccttattgaactttttcaagattttcacacttagaaat atcagaaggcagtacaaaaccattaagaggatgacgaccatggagttaattatgaaaatt ttctccttcttctggatgttgttcattggctttgtttgctttattttcaacatagtacaa ggatttttccagatcgtgtggagtgccatgtttggaggtgggctagttgaaggtgccaaa agcatcactgtcacagaccttttagccagcatgccagatccaacacaacttggaattcat ggagatgtgagcgaatcagaaagatcagaaactccagagctgggggttgttgcagaacat cagtctatagcacaagatgagaaaagtgaaactgaggtgatgcctgatatattcggtacg agtatgaaaaaaggaggcaaagcaggtgacgaacacggaggtcttggtgatgtgtcggaa attatcggagcagaaggccccctaagtattgaaaaagcaatatctcagaaaaagaaagca gagattgaacagaagaataaaaatgagagtaaaaccgagtttgagaaggctgacacagag gatggcgagaagatggacaaagccaaagaagaacaaccagatgaaagtgaagaaatagag caaaaaataaagaagaggcgacgtggacagacaaagaaggaaccagaagcattcttagtt aacttctgggaaggtcttgaaatttaccaaaccaagattctgaattatctagccaggaat ttctacaatttgaggttactagctctatttgtggcatttgcgatcaatttcattctactc ttctacaaggtgaccgagcctccagctgatgaagaagaagcggatttcagtttctggaat gatgacaaggtggatttctacgtgttgcaggagactacaggatacatggccccaacgcta acatttcttgcacttattcacacaatcatctcaatgctttgtatcattggctactacata ttgaaggtccctcttgtagttttcaagcgtgaaaaggaaattgccagaacgctggagttt gatggtctgtacataacagagcagccgtctgatgatgacattaaaggacagtgggatcgt cttgtcatcaacacgccatctttccctaataattactgggacaagtttgtcaaaagaaag gttattaataagtatggcgacctttatggagttgaacgtattggtgagctcctgggtgtg gacaaaagttctttagattttagtcccattgaagaggccccagagcgagaagcgacactg gtgtcctggttgagttccattgatttaaaataccatatttggaaacttggagttgtgttc actgataattcatttttgtatctggcttggtacacaaccatgtctattttgggtcattac aacaacttcttctttgctgcccacttgctggatattgctatgggttttaagacgttgcgt acgatattgtcatctgtaacacacaatgggaagcaggtgagaactattaaacacaaggtg tggttaatgtcttattattttcaatcttga

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