Leucoraja erinaceus (little skate): 129706968 Help Entry 129706968         CDS       T09122                                  Symbol tsc2 Name (RefSeq) tuberin isoform X1   KO K07207   tuberous sclerosis 2 Organism leri  Leucoraja erinaceus (little skate) Pathway leri04115   p53 signaling pathway leri04140   Autophagy - animal leri04150   mTOR signaling pathway leri04218   Cellular senescence leri04910   Insulin signaling pathway leri05168   Herpes simplex virus 1 infection Brite KEGG Orthology (KO) [BR:leri00001]  09130 Environmental Information Processing   09132 Signal transduction    04150 mTOR signaling pathway     129706968 (tsc2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     129706968 (tsc2)   09143 Cell growth and death    04115 p53 signaling pathway     129706968 (tsc2)    04218 Cellular senescence     129706968 (tsc2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     129706968 (tsc2)  09160 Human Diseases   09172 Infectious disease: viral    05168 Herpes simplex virus 1 infection     129706968 (tsc2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:leri01009]     129706968 (tsc2) Protein phosphatases and associated proteins [BR:leri01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      129706968 (tsc2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Tuberin DUF3384 Rap_GAP Cnd1 Motif Other DBs NCBI-GeneID:  129706968 NCBI-ProteinID:  XP_055507633 LinkDB All DBs Position 20:23187465..23279907 Genome browser AA seq 1860 aa AA seqDB search MSKLPSKDSSFRERVKSILGIGPRINTKQTESKPTEFIITFEILKELNIESGLYNRIKTI GHVCELARTRKFEEHAVEAVWQAVADLMSDDQPSEARLTVLQLMKAIIQGQGERLGPMRA HFFRVIKDYPMNSDLHERLDVFKALTENGKDITYLEEDLSSFVLKWMEIGLTVDFLEVLV NLVKFNSCYLDQIVAQIVHKICVLCNLTTVATDIEVSLQVLDAVVCYNSLPSESLPGFII TLCRTVNVKEFCESCWKLMRKVLGTHLGHSAIYTMCRIMEDRMHMDDAALLRGAVFFVGM ALWGAHRLATLKSTPTSVLPSFYKAMTSANAVVSYEIVLSITRLIKKYGKELQVVTWEQL MDIIERLLQQIETLGSNELSVIVHELLTTIEELYELNDYHGPHERLFALIEKCSNKRPEI SVLTLVSYRAQSIHPAKHCWIQNLQKLMDKFFKNENRSTIRKKALDVLLFVLSINRQLYE EELIEAVVIPQLGHVAEDKDHMVRRLAAQLLVDLAVDCHTPQFNSLLDIIEKVINRPLID PSVVEAVESNFLYDSPLEDVKTAVLGLLEILQTKLYSLPASHAGRVYELLISHIQSHYLQ MYSSAIASSIRLKVFNFFLHLRADSLFRIGVPNKDKIVRFSPYCFCGSSDSEKKGQGTVS PPAGSPATAQSATIRLGYLPFSLAFNAILQCLERETDWKVLKLVLDKLQELLKYKGLILT SPCSIDQLCSALCTMVTDRQLAERLRNTPEGFSRTDVQLVVVPVLTVITSYHVYLDQSKQ REFVHCLDTGLIYRCAKQCVVTLTMCIIEMPDIMVKLLPGIILKLTHISATLTMAIPMLE FLSTLVRLPPLYANFVAEQYVSVFAISLPYTNPFKFNQYIVSLAHHVIAMWFIRCRLVFR KDFVRYITKGLRSNALLPFEDTHEPSSFRARSTSLNERPFKSLRGSKPQKPGLNSSQIKD MKDLSAVEAFRSRSISVSEHAVRRMQTSVTSSSLGSSDENSMADAEHSLKTVHLELTETC LDMMARYVFSNFSALPKRSPIAEFLLGAGRSNTWLVGNKLVTVTTSSGMGTRALMGLDSL EQKNTEETSRLDLSMQVKTTQEAPAKLESQASQQIGKAARLRVRSVSGGHALHSDSVQSL SPLVSPSESEISAPSVMAATKGLENRKSLHRDAAPSSGQPLSQKEKANLAEYASVLTQGW AEIYIRRPSGNASWLLCLENPPSPFSSEINNMPLQELSTMLMAVERVTDSHQQAPGRSES MPCPSLTAKPPILQRFNTVASFSSMCQTSCRGELHRSISWADSVAVAEEGDGLGMHLKAC DSPVESHELEDFEAMVSEPIFMPAESQDMITASYSRSSSTSSQEEEKTLQGEDPGIMGIA SDKVVPSSLAIDPLEEEFDFNHAQTLNKSSSSPELQNLQEMAEVNGKEGPAAKPATEAKP RSHAESIEEECPPNGRLETSDGSKQDTLPPAEKKEPPLSPNRYRPRGHTISDSAPSRRGR RSQRNGVQNRASASNAEKISGINPSFVFLQLYHSPFFGSESNKPLLIPKNEITDRAIKVL DQMPPYDTHKIGVVYVGEGQTNNEVEILSNAYGSSRYAQFLTGLGKLIYLQDCNPEQIFL GGLDTYGDDGQFTYCWHDDIMQAIFHIATLMPNKESDRACCNKKRHIGNDYVVVIYKDTE EEYKLGTIKGQFNFVEIIIKPLDFESNLVTLQARQDMEGLVDTSVARIVSDKNLPLLVRQ MALHANMASLVHHKSAVPSEAYASKWLARLRQIKRIRSKVCEDLQYRQNAGISLIHMHAA NQSKSSHHHHHHHHHHQAQQQHLPHHHYLPQHLSQSQSAGSETGQRKRLMSTVDDFTDFV NT seq 5583 nt NT seq  +upstreamnt  +downstreamnt atgtccaagcttccgagcaaagactcgtcctttcgtgaacgagtcaaaagtattctgggc attggtccccgcattaacaccaagcaaacggaatccaagcccacagagttcatcatcaca ttcgaaatattaaaggaactgaatatagagagcggactctacaatagaataaaaaccatt ggacatgtttgtgagctcgccaggaccaggaagtttgaagagcatgcggtggaggctgtg tggcaggcagtggctgacttgatgtcggatgatcagccctcggaggccagactcacagta ctgcagttaatgaaagctattattcagggacagggggaaagacttggaccaatgcgagca cactttttccgtgttatcaaggattaccctatgaacagtgatctgcatgagagacttgac gttttcaaagcactaacggaaaatggaaaagacatcacctatctggaagaagacctgtcc tcgtttgttctcaaatggatggaaattggtctgacggtggactttctggaggtgcttgtc aacctggtcaaattcaacagttgctacttggaccagattgtggcccaaatagtacataag atctgtgttctctgtaatctgaccacagtggcaacagatatagaggtctccttgcaagtc ctcgatgcagttgtctgctacaactctttgccttctgagtctctcccgggatttattatt acactctgtcgtacagttaatgtcaaggaattctgtgaatcttgttggaagctaatgcgc aaagtcttgggaactcacctgggacacagtgcaatttatacaatgtgtcgtataatggag gacagaatgcacatggatgatgctgctttgctgagaggtgccgtattctttgttggaatg gctctctggggtgcacatcgtctcgctaccctgaagagtaccccaacatctgttttgcct tctttttacaaggctatgacgagtgccaatgctgtggtatcctatgaaattgttctttcc atcactcgactgatcaaaaaatatggaaaagaactgcaggtggttacttgggaacagctt atggatatcattgagcgattgcttcagcaaattgagacactgggtagtaatgagctgtca gttattgtacatgagctgctaaccacaatagaagagttgtatgaactgaacgactatcac ggtcctcacgaacgattatttgcactgattgaaaaatgttccaataaaaggccggagatc tccgtccttacactagtgtcgtaccgggctcagtctattcacccagccaagcactgctgg attcagaatctgcagaaactaatggataagttcttcaagaatgaaaatcgaagcaccatt cgcaagaaagctctggacgtcttgttgtttgttttgagcattaatcgacaattatatgaa gaggagctaattgaagcagtggtgatccctcaacttgggcatgttgcagaggataaggat cacatggtacggagattggctgcacagctgctcgtagacctggcagtggactgccacacg cctcagtttaacagtctcttggacatcatagaaaaggttatcaatcgaccactcattgat ccatctgttgtagaagcagtggaaagcaactttctatatgattcacctctggaggacgtg aagacagcagtcttgggtcttctggaaattctgcagaccaagttgtacagtttgcctgcc agccatgcgggtcgagtctatgaactcctgataagccacatacagtcacattacctgcaa atgtactcctctgctattgccagcagtattcgcctgaaggtgtttaattttttcctgcat ctccgagcagactctctctttcgaatcggagtgccaaacaaggacaagattgtaagattc agtccctattgtttctgtggaagcagtgattctgagaagaaagggcaaggtactgtctct ccaccggcaggaagtccggccacagctcagagtgccaccattaggctgggttacctgcct ttctctctggctttcaatgcaattctccagtgccttgagcgtgagacagactggaaggtg ctgaaactcgtattggataagttgcaagagttgctcaagtacaaaggactgattctaact tctccgtgcagcattgaccaactctgctcagctctctgtaccatggtcaccgaccgtcag ttggcagagaggctgcggaatacgccggagggtttctcccgcacggatgtccagttggtg gtggttcccgtgctgacggtcatcacctcctaccatgtttacttggaccagagcaagcag cgtgagtttgttcattgcctcgatactgggctcatatatcgatgtgcaaagcaatgtgtg gtgaccttgaccatgtgcatcatcgagatgcctgatatcatggttaagctgctaccgggc atcatcctcaaactgacccacatctctgccacgctcaccatggccattcccatgctggag ttcttatcaaccttggtgagacttcctcctctctatgccaactttgtggcagaacagtat gtcagtgtgtttgctatatcgttaccatacactaaccctttcaaattcaaccaatatata gtgtccctagcacaccacgtcatagccatgtggtttattcggtgtcggcttgtgttcagg aaggactttgtgcgatacattacaaaaggtctccgatcaaatgccttgctaccatttgag gatacacatgaacccagcagctttcgagctcgtagcacaagcttaaacgaaagaccattc aaaagcttgcgaggctcaaagccccaaaagccaggcttgaatagttcacaaattaaagat atgaaagacctatcggcagttgaggccttccggtcccgaagcatcagtgtctcagaacac gcagtccgaagaatgcaaacctctgttacgagttctagtttgggatcgtcagacgagaat tcaatggcagatgcggaacacagtctaaaaactgtgcaccttgaacttaccgaaacgtgc ttggatatgatggctcgatacgttttctccaacttctctgctctgcccaagaggtcccct atagcagaatttctccttggcgcaggaaggagtaatacgtggctggttggaaacaagctg gtcacagttaccactagcagtggtatgggaacaagagcactgatgggtttggattccttg gagcagaagaacactgaagaaacatccaggttggatttgtcgatgcaagtaaagacaaca caagaagcccctgccaagttggagtctcaagccagccagcagattggaaaggcagctcgc ttgcgagtgagatccgtatcaggtggtcatgctctccacagcgattcagttcagagttta agtcctctggtgtcgccctcggagtccgagatctctgctccctctgtgatggcagctaca aaaggattggaaaaccgcaaatcactgcatcgggatgcagccccctctagtggccagcct ctctcacagaaggaaaaggccaacctggctgaatatgcctcagtcctgactcagggatgg gcagaaatatacattcgccgaccctcgggtaatgcaagctggcttctgtgtctggagaat ccaccaagcccattttcttcagagataaacaacatgcccttgcaagagctgtccactatg ctgatggctgtagagagagtgacggactcacaccagcaagcacctggtcgatcagaatcc atgccctgccccagcttaacagccaagccaccaatacttcagcgtttcaatacagtggct tctttctcttctatgtgccagacaagctgtcgaggagaattgcacaggagcatttcctgg gcagattcggtggctgtagcggaggaaggtgatggactgggcatgcacttgaaggcctgt gattctcctgtggagtctcacgaactcgaggactttgaggcaatggtttccgagccgatc ttcatgccagcagagagccaggacatgattacagcatcatacagcagatcgtcatcaacg tccagtcaggaggaggaaaagactcttcagggagaagatccagggataatgggcattgcc tctgataaggttgtgccatcttctttggccattgatccattggaggaagaatttgatttc aaccacgctcaaactctcaacaagtccagctcttccccagagcttcagaacctccaagaa atggcggaggtaaatgggaaagagggacccgctgcgaagccagcgactgaggcaaagcct aggagtcatgctgagagtattgaagaggaatgtcctcccaatggcagattggaaaccagc gacggtagcaagcaggacacactacctccggcagaaaagaaggaaccccctctgtctcca aaccgctacaggcccaggggccacaccatttctgactctgcaccgtcaaggagaggccgg aggtcacagcgcaatggggttcagaacagagcgtcggcctcgaatgcggagaagattagt ggaataaacccaagttttgtgtttcttcagttatatcattcgcctttctttggtagtgag tcaaacaagccacttctcattcctaagaatgagattacagaccgcgccattaaagtcctt gatcagatgccaccttacgatacacacaagattggagtggtgtatgttggggaaggacag actaataatgaagttgaaattctgtccaatgcatatggatcgtcgaggtatgcacagttc ctcactggccttggtaaattgatctatcttcaagactgcaacccagaacaaatattcctt ggtgggcttgacacttacggtgatgatgggcagtttacttactgctggcatgacgacatc atgcaagcaatctttcacatcgcgaccctgatgccgaacaaagaatcagatcgagcctgt tgcaacaagaaaaggcacattggaaatgactatgtggtggttatatacaaggacactgaa gaggagtacaaactgggaactataaagggccagtttaactttgtggaaataataattaaa cctctggactttgaaagcaacctggtaacactacaagcacgccaagatatggaggggcta gttgacacaagtgtggctaggattgtgtccgacaagaacctccctctcttggtgcgtcaa atggctttacatgcaaatatggcttctcttgtacaccacaaaagtgcagttccttcagaa gcctacgcaagcaagtggctagcgaggctacgccagatcaaacgtattcgatccaaggta tgcgaggatctgcagtatcgtcagaacgccgggatctctctgatacacatgcacgctgcg aaccagagtaagagctcccaccaccaccatcaccaccaccaccaccaccaagcacagcag cagcatctccctcaccaccattacctcccacagcacctgtcgcagtcacagtctgctggg agcgagactggccagaggaagcggctgatgtccaccgtggacgatttcacagactttgtt tag

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