KEGG   Leucoraja erinaceus (little skate): 129710062
Entry
129710062         CDS       T09122                                 
Symbol
erbb2
Name
(RefSeq) LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-2
  KO
K05083  receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
Organism
leri  Leucoraja erinaceus (little skate)
Pathway
leri04010  MAPK signaling pathway
leri04012  ErbB signaling pathway
leri04020  Calcium signaling pathway
leri04510  Focal adhesion
leri04520  Adherens junction
leri04530  Tight junction
Brite
KEGG Orthology (KO) [BR:leri00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    129710062 (erbb2)
   04012 ErbB signaling pathway
    129710062 (erbb2)
   04020 Calcium signaling pathway
    129710062 (erbb2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    129710062 (erbb2)
   04520 Adherens junction
    129710062 (erbb2)
   04530 Tight junction
    129710062 (erbb2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:leri01001]
    129710062 (erbb2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:leri04147]
    129710062 (erbb2)
   04090 CD molecules [BR:leri04090]
    129710062 (erbb2)
Enzymes [BR:leri01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     129710062 (erbb2)
Protein kinases [BR:leri01001]
 Receptor tyrosine kinases (RTK)
  EGFR family [OT]
   129710062 (erbb2)
Exosome [BR:leri04147]
 Exosomal proteins
  Exosomal proteins of breast cancer cells
   129710062 (erbb2)
CD molecules [BR:leri04090]
 Proteins
  129710062 (erbb2)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Recep_L_domain GF_recep_IV Pkinase Furin-like TM_ErbB1 Haspin_kinase ABC1 Tcell_CD4_C Syndecan
Other DBs
NCBI-GeneID: 129710062
NCBI-ProteinID: XP_055512726
LinkDB
Position
27:482998..523715
AA seq 1180 aa
MVALVLTPWAGVAPLLLLLYGALGRDPLPTPQVCPGTDMKLKLAFSLENHYHTLRKLYEN
CREVQGNLEITHLKGNLDLTFLKNIQEVQGYVLLAHNEVDYIPLENLRIIRGSQLYEGRY
ALAVISNLNSSTTGLRELRLRSLTEILIGSILIRNNPWLCYQETIQWDDIQDANNILQFP
FLGTVDSNRTVKCGNCSRGCESCWSSGPEYCQTLTRKICAHECRTRCRGRQPSECCHNEC
AAGCTGPKDTDCLACHRFNNAGMCSRNCPPLSIYDVQTYQMKPNPEATYIFGANCVKKCP
HNYLATNVGSCTLDCPNDTKEVMEGDRYKCEKCSEPCPRVCSGLGVSKLKNVRAVTSRNI
DSFKGCSKIFGSLVFLAETFSGDPATKTEPLDVRKLKVFDVLTEITGYLYIEAWPQNFTS
LKAFENLATIRGRVLYSSAYALLVQNLQIQWLGLRSLKEISNGLVFIHQNPHLCYIKTIP
WRQLYQKEHQEELITANRPQDVCEAEGHSCYALCTAGNCWGPGPTQCLACTHYLRAQRCV
ETCNLYMGQVREYLSESSCIACHAECLPQNDTLSCSDKGADACVACRHYKDGKQCVEKCP
TGVHGHIWKYPDEQGLCQLCPTNCSHSCTTSADGCPEEPSHSQVTSVVAGIVGALLFMVL
IILFIVWWRRKIYLSQKHKRMSLMEQNKLVEPVSPSGVVPNQAQIRILKETEMKKVMVLG
SGAFGTVYKGVWMPEDEDVRIQVAIKVLREGTSPKANKEILDEAYIMAGVSSPYVCRLLG
ICLTSTVQLVTQLMPFGSLLDYVRENKDRIGSQHLLNWCVQIAKGMNYLEDHVRLVHRDL
AARNVLVKSLNHVKITDFGLARLLDTDETEYHADGGKVPIKWMALESILHRRFTHQSDVW
SYGVTVWELMTFGAKPYDGIPAREIHELLEKGDRLPQPPVCTVHVYMIMVKCWMIDSEST
PRFGQLVTEFTRMARDPPRYIVIQGDDRLVPQSPTDSKFYRTLLEDEEMQNLIDAEEYLS
ARSVAEVDGRGTVTAAGPASPDPPGEGDRSAHRGTVSCPTAEHGLVQRYSSQPSLWPDLD
GLEVDAYIALGCQAPGYLNQAGERAGGSGMGVSVPAATLGKTVENPEYLSHHSLEQDHWG
GDHQRAEPMWTPGPAQPNGYIRVAAAENPEDLGLTETSSV
NT seq 3543 nt   +upstreamnt  +downstreamnt
atggtggctctggtgctgactccctgggctggtgttgccccactcttgctgctgctgtac
ggagccctgggccgagacccgctccccaccccacaagtatgtccagggaccgacatgaag
ctcaaactcgccttcagtttggaaaaccattaccacactctgcgcaagctgtacgagaat
tgccgcgaggtgcagggcaacctggagatcacacacctgaaagggaaccttgaccttacc
ttcctgaagaatattcaggaggtgcaaggctatgttcttcttgctcacaacgaggttgac
tacattccactggagaatctgcgcatcattcggggaagccagctgtacgagggccgctat
gcactggccgtcatctccaacctcaactctagcaccactggcctccgggagctacggctc
aggagcctgacagagatcctgattgggagtatcttgattcgcaacaacccctggctgtgt
taccaggagactatccaatgggatgacattcaagatgccaacaacatcttgcagttcccg
tttctgggcacggtagacagcaacaggaccgttaaatgtgggaactgcagtcgtgggtgt
gagtcgtgctggagctcggggcccgagtattgccaaacactgactcggaagatctgtgcc
catgagtgtcggacccgctgcagagggaggcaacccagcgagtgctgccacaatgaatgt
gctgctggctgtactgggcccaaggacaccgactgccttgcctgccaccgtttcaacaac
gcggggatgtgcagtaggaactgtccccctctcagcatctatgatgtgcagacctatcag
atgaagcccaaccctgaggcaacgtacatctttggagccaactgcgtcaaaaagtgtccg
cataattacctggccacgaatgtgggctcgtgtacgctggactgtcccaacgacaccaag
gaggtgatggaaggagatcgatacaaatgtgagaagtgcagtgaaccgtgtcctagagtg
tgcagcggcttaggggtgagtaagctgaagaatgtgcgggcagtgacctccagaaatatt
gattccttcaaaggctgcagcaagatctttggcagcttggtcttcctggctgagaccttc
tctggtgacccggctacaaagactgagcccctggatgtgaggaagctgaaggtattcgac
gttctgactgagatcacagggtatttatacatcgaggcttggccacagaatttcaccagc
ctgaaggcctttgagaaccttgccacgatccgggggcgagtgctatacagcagtgcttat
gcattgttagtgcagaatctacagatacagtggctcggactacgctctctaaaagagatc
agtaatgggctggtgttcattcaccaaaatcctcacctctgttatatcaagactattccc
tggagacagctgtatcagaaggagcaccaggaggagctgataacagccaacaggccacaa
gatgtttgtgaggccgaagggcattcgtgttacgccctgtgtacggcgggcaattgctgg
ggtcctgggcccacacagtgcctggcctgtactcactacctgcgtgcgcagaggtgtgtg
gagacgtgcaacctgtacatggggcaggttcgggagtatctgagtgaatcgtcgtgtatc
gcatgtcatgcagagtgtctccctcagaacgacaccctgagctgcagcgacaagggcgct
gatgcctgcgtggcatgcaggcattacaaggatggcaagcaatgtgtggagaaatgcccg
actggggtacatgggcacatctggaaataccctgacgaacaaggcctctgccaactctgc
cccactaactgcagccactcatgtacaaccagtgctgacggatgccccgaggagcccagt
cacagccaggtgacgtcggtggtggccggcattgtgggcgctctgctcttcatggtactc
atcatcctcttcatcgtctggtggagacgcaagatctacctcagccagaagcacaagagg
atgagcctcatggaacagaacaagctcgtcgaacctgtgagcccaagtggggtcgtacca
aaccaggcgcagatacgaatcctaaaggaaacggaaatgaagaaagtcatggttctggga
tctggagcctttggaacagtttacaagggagtctggatgccagaggatgaagacgtcagg
atacaagtggccattaaagttctacgcgagggaacttcccccaaagcaaacaaagagatc
ctggatgaggcatacatcatggcgggagtgagcagcccctacgtgtgccgactgctgggc
atctgcctgacctccaccgtacagctggtcactcagctcatgcctttcggctcactgctg
gattacgtgcgtgagaacaaggaccgcatcggctcacagcatctcctcaactggtgcgtg
cagatcgccaaggggatgaattaccttgaagaccatgttcgattggttcaccgtgacctg
gctgccaggaacgtgctggtgaagagtttgaaccacgtgaagatcaccgactttggcctg
gcccgtctgctggacacggatgagacggagtaccatgcggacggtgggaaggtccccatc
aaatggatggccctggagtccatcttgcaccggagattcacgcaccagagtgacgtctgg
agttacggcgtgaccgtgtgggagttgatgacgttcggggccaagccgtacgatgggatc
ccagcgcgggaaatccatgagctgctggagaagggggaccgtctgccccaaccgcccgtc
tgcaccgtccacgtctacatgattatggtcaagtgctggatgatcgactcggagtcaacg
ccccggttcgggcagctggtgacggagttcacgcggatggcacgggacccaccgcgatac
atcgtcatccagggcgacgaccgtctggtcccacagagcccgactgacagcaagttctac
cggacgctgctggaggacgaagaaatgcagaacctcatcgacgcggaggaatacctgagt
gcgcggagtgttgctgaggtggacggtcgagggacagtgaccgctgcgggccccgccagc
ccagacccccctggcgagggggaccgctcggcccacagggggacggtttcctgcccgacc
gctgagcacgggctagtccagcgctatagctcacagcccagtctgtggccggacttggac
gggctggaggtggacgcctacattgccctgggctgccaggccccaggctacttgaaccag
gcgggtgagcgtgcggggggatcggggatgggagtgtctgtaccggcagctacgttgggg
aagacggtggaaaacccggagtacttgtcccaccacagcctggagcaggaccattggggc
ggggaccaccagcgggcagagccaatgtggaccccgggccccgcacagcccaacggatac
atccgtgtagctgccgcagagaacccagaggacctgggcctgacggagaccagcagcgtg
tag

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