Limosilactobacillus frumenti: LF145_01255
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Entry
LF145_01255 CDS
T06870
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
lfn
Limosilactobacillus frumenti
Pathway
lfn00300
Lysine biosynthesis
lfn00550
Peptidoglycan biosynthesis
lfn01100
Metabolic pathways
lfn01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
lfn00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
LF145_01255
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
LF145_01255
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
LF145_01255
Enzymes [BR:
lfn01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
LF145_01255
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
RecA-like_ORC2
Motif
Other DBs
NCBI-ProteinID:
QFG72086
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Position
289570..290952
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AA seq
460 aa
AA seq
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MKMKLAEIASAIGVQNEISQWQDVEITSVAFDSRELEAGALFVPLQGAQDGHQFVQSAFD
NGAAATLWASDHDVTTNPDQPVLVVADPLKALQKLSKYYLHKINPIVVAVTGSNGKTTTK
DMTASILSTQLNVTKTHANFNNEIGVPVTLLNMESNTEVVVVEMGMDRFGQLDFLSRLVS
PDIAVITMIGEAHIEFFGTRDKIADAKMEIVHGLKEDGALVYNGDEPLLQERTRDLAQDR
ITFGRHLDDDFYATSVHLHERSIDFKVNQWPDMDFTIPMVGEYNVNNALAAIAVGQRLHI
SPQHMKQALKDVELTENRAEWVKGSNGEQILSDVYNSNPTAARQVLKTIAETPTSGHRIA
VLGDMLELGDAAPRLHASLAANIDHDHIQQVYLIGSNMKYLQDKLIQDGYPAVDVHYYPD
DGLAQLTTDLQRALTADDMVLLKASHGIHLEEVLRALTNK
NT seq
1383 nt
NT seq
+upstream
nt +downstream
nt
atgaagatgaaattagccgaaattgcttcagcaatcggcgttcaaaatgaaataagtcag
tggcaagacgtggaaataaccagcgttgcctttgacagtcgtgaattggaagctggtgca
ctgtttgttccactacaaggggcacaagacggtcaccagtttgttcagagtgcctttgat
aatggtgcagcagcaaccttgtgggctagtgaccatgatgtcactacgaaccctgatcaa
ccagttttagtggtggctgatccgttgaaggcattgcaaaagctcagtaaatattattta
cataagattaacccgatcgtggttgcggtgacggggagcaatggtaaaaccacgactaaa
gatatgacggcctctattttgagtacgcaactgaatgtaacgaagacgcacgctaacttt
aataatgaaattggcgttcccgtgacattattaaacatggaatcgaatactgaagttgtg
gttgttgaaatggggatggaccgttttggtcaactagacttcttaagtcggttggtttct
ccagatatcgctgtaattacgatgatcggcgaagcccatattgaattcttcggcacccgg
gataagattgcggacgccaagatggaaattgttcatggtctcaaggaagatggggccctg
gtctacaatggtgatgaaccattactccaggagagaacacgtgacctggctcaggatcgg
attacctttggtcgtcaccttgatgatgacttctacgctactagtgttcacctgcatgag
cggtcaattgactttaaggttaaccagtggccagacatggacttcacgattccgatggtc
ggtgaatataatgttaataacgcattggcagcaattgcggttggccagcggttgcatatt
agtccccaacacatgaaacaggcgttaaaagatgttgagttaaccgaaaatcgtgctgag
tgggttaaggggagtaatggcgaacagatcttgtctgatgtttacaactccaatccaacc
gctgctcgccaggttttaaagacgattgcggaaacaccaaccagcgggcaccggatcgca
gtgttaggcgatatgttggaactcggagacgctgctccgcgtttgcacgctagtctagct
gctaatatcgatcatgaccatattcagcaggtttacctgatcggtagtaatatgaagtac
ctgcaagataaattgattcaggatggttatccagcagtggatgtccattattatccagat
gatggtttagctcaactaacaacggacctccagcgagcattgaccgctgacgacatggtc
ttgttgaaagctagtcacggtattcaccttgaggaagttttgcgggcattaacaaataaa
taa
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