Limosilactobacillus fermentum CECT 5716: LC40_0150
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Entry
LC40_0150 CDS
T01958
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
lfr
Limosilactobacillus fermentum CECT 5716
Pathway
lfr00300
Lysine biosynthesis
lfr00550
Peptidoglycan biosynthesis
lfr01100
Metabolic pathways
lfr01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
lfr00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
LC40_0150
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
LC40_0150
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
LC40_0150
Enzymes [BR:
lfr01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
LC40_0150
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ADJ40811
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Position
254293..255672
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AA seq
459 aa
AA seq
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MKMSLAEIAQAIQAHNQVDKWGDIEVRSVAFDSRNLEAGGLFVPLKGEQDGHQYVAKAFE
NGAKATLWAKDHPYDPADGYPRLVVDDPLKALQQLGKYYLNKINPVVVAVTGSNGKTTTK
DMVASILATQMNVIKTYANFNNEIGVPVTLLNMEANTEAVVVEMGMDRFGQLDLLSRLTT
PDIAVVTMIGEAHIEFFGSRDKIADAKMEITHGLAEDGTFVYDGDEPLLRERAAKLSQQT
KTFGRQLDDDLYATSVNPDVDHVSFTVNQWPDEVFTIPLVGEYNVNNALAAMTVGKLMHV
TPANMKQALQNVELTENRSEWVAGANGERILSDVYNSNPTAVKEVLATLATIPVAGKRVA
VLGDMLELGEASARLHAGLCDAIMNGHLDEVYLIGGEMGALKDALLKAGYPAGQLHYYQA
AQRKALTDALQASLTTGDVVLLKASHGLHLEKVLAQLEK
NT seq
1380 nt
NT seq
+upstream
nt +downstream
nt
atgaaaatgagcttagctgaaattgcccaggcaattcaggcccacaatcaggttgataag
tggggagacattgaggtgagaagtgtcgctttcgattcgcggaatttggaagcggggggc
ttgtttgtgcccttaaagggggaacaagatggtcaccaatacgtggccaaggcttttgaa
aacggggcgaaagcgaccctgtgggctaaagatcacccttatgatcccgctgatgggtac
ccacggctcgtggttgatgacccccttaaagctttgcaacaactggggaagtactaccta
aacaagattaaccccgttgtcgtggcggtgacgggaagtaacgggaagacgaccaccaag
gacatggtggcgtcaatcctggcgacccaaatgaacgtcattaagacctacgccaacttc
aacaacgaaattggcgttccggtcaccctcttgaacatggaagccaataccgaagcggtg
gtggttgaaatggggatggaccgctttggtcaattagacctgttaagccggttgacgacg
ccggatattgcggtggtgacgatgattggggaagcccacatcgaattctttggtagccgc
gataagatcgccgacgccaagatggagatcacccacggtttggccgaagacgggaccttt
gtttatgacggtgacgaaccgctattgcgggaacgggccgcgaagttgagccaacagact
aagacctttggccgccagcttgatgacgacctctacgccactagcgttaacccggacgtt
gaccacgtcagcttcacggttaaccaatggccggatgaagtcttcaccattccgctggtc
ggggagtacaacgtcaacaacgccctggccgcaatgacggtcggcaagctgatgcacgtc
acccccgctaacatgaagcaagccctgcaaaacgttgagctaaccgaaaaccgctccgaa
tgggtggccggggctaacggtgaacggatcttgagtgatgtttataactccaaccccacc
gccgttaaagaggttttagccaccctagccacgattccggtcgctggtaagcgggtggcc
gtcttaggggacatgctagaactcggggaggcttccgcacgcttgcacgccggtctttgt
gacgccatcatgaatgggcacttagatgaagtctacttaattggtggcgagatgggcgca
ttaaaagacgccctcttaaaggcgggctacccagcggggcaactgcactactaccaagcg
gcgcaacgcaaggccctgaccgacgctttgcaagctagtttaacgaccggggacgtggtc
ttattaaaggctagccacggtctgcatttagaaaaggtgttggcccaactcgaaaagtag
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