Lactobacillus gasseri ATCC 33323: LGAS_0264
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Entry
LGAS_0264 CDS
T00410
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
lga
Lactobacillus gasseri ATCC 33323
Pathway
lga00300
Lysine biosynthesis
lga00550
Peptidoglycan biosynthesis
lga01100
Metabolic pathways
lga01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
lga00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
LGAS_0264
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
LGAS_0264
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
LGAS_0264
Enzymes [BR:
lga01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
LGAS_0264
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ABJ59672
UniProt:
A0A805YSK0
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Position
296783..298150
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AA seq
455 aa
AA seq
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MKMQLAEIAKALNSSVNMGEDKVITSVVFDSRKATPNSLFIPLAGVRDGHDFVSNAMANG
AEATLWKKGHEGKPTDVPVIEVEDPLTALQSLAKYYLGKVNPTVVGITGSNGKTTTKDMV
AAVLAKRFNVHKTQANFNNEIGVPVTILEMKPSTEILVLEMGMDRPGQLHHLSELVRPDV
CVITMIGEAHIEFFGTRDKIADAKMEITDFLKEDGKFIYNGDEPLLEERAAKIKQDKSTF
GFREEDTVFATTFRSYMHHATFEINDSEQQFKIPMIGKHNVSNALAAISVGRHFGENDEQ
IAQALANFTPTANRMQWKKGDVGEAIMDDVYNSNPTAVKAVTTSFGQVMVQDGGRRIAVL
GDMLELGDESAELHASLANALDPAIINELYLYGPEMKNLYDALVDKYPAANLHYYPQDEM
NHMIDDLKNDIKPADIVMLKGSHGMHLEKVLDRLM
NT seq
1368 nt
NT seq
+upstream
nt +downstream
nt
atgaaaatgcaacttgctgagatcgccaaagcattaaatagttcagttaatatgggagaa
gataaggtcatcacttctgttgtttttgattcaagaaaagcaactcccaattctttattt
atcccattagcaggtgtaagggatggacatgattttgtatctaatgcaatggcaaatgga
gcagaagcaactttatggaaaaaaggccatgaaggtaagccaactgatgtgccagttatt
gaagttgaggatccattaacagcacttcaatctttagctaaatattacttaggtaaagtt
aacccaactgttgttggtattactggttctaacggtaagactacaactaaggatatggtt
gcagctgttttagctaaaagatttaatgttcataagacacaagccaattttaataatgaa
attggtgttcctgtaaccattttagagatgaaaccatccactgagattctagtacttgaa
atggggatggatcgcccaggacaattacatcatttaagtgaattagtaagacccgatgtt
tgtgtaattaccatgattggtgaagctcacatcgaattctttggtactagggataaaatt
gctgatgctaagatggaaattactgatttcttaaaagaagacggtaagtttatttataac
ggtgatgaaccattgttagaagaacgcgcagctaagattaagcaagacaagagtactttt
ggatttagagaagaagatactgtttttgcaactacttttagatcttacatgcaccacgct
acttttgaaataaatgattcagagcagcagttcaaaattccaatgattggtaagcataat
gtgtctaatgctcttgcggcaattagcgtaggacgtcactttggcgaaaatgatgagcaa
attgctcaagcattggctaactttactccaactgcaaacagaatgcagtggaaaaaggga
gacgtaggcgaagcaattatggatgatgtttacaattcaaatccaactgcagttaaggct
gttactacttcatttggccaggtgatggttcaagatggtggacgtagaattgcagtcttg
ggtgacatgttagaacttggggatgaatctgctgaacttcatgcttcacttgctaatgcc
ttagatccagcaattattaacgaattatatttatatggtccagaaatgaagaatttgtat
gatgcacttgttgataaatatccagcagcaaacttgcattattatccacaagatgaaatg
aatcatatgattgatgacttaaagaatgatattaagccagctgatattgtcatgctaaaa
ggatcacatggaatgcatttagaaaaggttttagaccgcctaatgtag
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