Leopardus geoffroyi (Geoffroy's cat): 123585836 Help Entry 123585836         CDS       T10761                                  Symbol PKLR Name (RefSeq) pyruvate kinase PKLR isoform X1   KO K12406   pyruvate kinase isozymes R/L [EC:2.7.1.40] Organism lgf  Leopardus geoffroyi (Geoffroy's cat) Pathway lgf00010   Glycolysis / Gluconeogenesis lgf00620   Pyruvate metabolism lgf01100   Metabolic pathways lgf01200   Carbon metabolism lgf01230   Biosynthesis of amino acids lgf04910   Insulin signaling pathway lgf04930   Type II diabetes mellitus lgf04932   Non-alcoholic fatty liver disease lgf04950   Maturity onset diabetes of the young Module lgf_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate lgf_M00002   Glycolysis, core module involving three-carbon compounds Brite KEGG Orthology (KO) [BR:lgf00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     123585836 (PKLR)    00620 Pyruvate metabolism     123585836 (PKLR)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     123585836 (PKLR)  09160 Human Diseases   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     123585836 (PKLR)    04950 Maturity onset diabetes of the young     123585836 (PKLR)    04932 Non-alcoholic fatty liver disease     123585836 (PKLR)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:lgf04147]     123585836 (PKLR) Enzymes [BR:lgf01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.40  pyruvate kinase      123585836 (PKLR) Exosome [BR:lgf04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    123585836 (PKLR) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK PK_C IMPDH HpcH_HpaI Motif Other DBs NCBI-GeneID:  123585836 NCBI-ProteinID:  XP_045310298 LinkDB All DBs Position C3:complement(1371715..1380706) Genome browser AA seq 578 aa AA seqDB search MSWGNVFNLPQPLSPSLESGDTCRARNGTCPTGSLEPGPAGYLRRVGGAQLAHELGTAFF ERQQLSAAMADTFLEHLCLLDIDSEPVAARSTCIIATVGPASQSVERLKEMIKAGMNIAR LNFSHGSHEYHAQSIANIREAVQSFATSPLSYRPVAIALDTKGPEIRTGVLRGGPETEVE LVKGSRVLVTVDPAFRTRGDASTVWVDYPNIVKVVSVGSRIYIDDGLISLQVQKIGPEGL ETHVENGGVLGSRKGVNLPGTQVDLPGLSEQDARDLRFGVEHEVDIVFASFVRKASDVAA IREVLGPEGRNIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPPEKVFLAQKMM IGRCNLAGKPVVCATQMLESMIAKPRPTRAETSDVANAVLDGADCIMLSGETAKGKFPVE AVKMQHAIAREAEAAIYHRQLFEELRRVAPLSRDPTEVTAIGAVEASFKCCAAAIVVLSK SGRSAQLLSRYRPRAMVIAVTRSAQAARQAHLFRGVFPVLYSKPPEAIWADDVDHRVQFG IESGKLHGFLRVGDLVIVVTGWRPGSGYTNIMRVLSVS NT seq 1737 nt NT seq  +upstreamnt  +downstreamnt atgagctggggcaatgtatttaatcttcctcaacccctgtctccttctctggaaagtggg gacacttgtagagcacgtaatggtacttgccccacaggatccttggaaccagggccagcc gggtacctacggcgggtcggcggggcccagctggcccacgagctgggcaccgccttcttc gagcggcagcagctgtcggccgccatggcggacaccttcctggagcacctgtgcctgctg gacatcgactcggagcccgtggccgcccgcagcacctgcatcatcgccaccgtcgggccg gcctcgcagtcggtggagcgcctcaaggagatgatcaaggccgggatgaacattgcgcgc ctcaacttctcgcacggctcccatgagtaccacgctcagtccatcgccaacatccgggag gccgtgcagagctttgcaacttctccgctcagctaccgacccgtggccatcgctctggac accaagggacccgagatacgcaccggggtcctgcgggggggccccgagaccgaagtggag ctagtgaagggctcccgggtgctggtgaccgtggacccggcgttccggacgcggggggac gcgagcaccgtgtgggtagactaccccaatatcgtcaaggtcgtgtcggtggggagccgc atctacatagacgacgggctcatctccctccaggtgcagaaaatcggcccggaggggctg gagacccacgtggagaacggcggcgtcctgggcagccgcaagggcgtgaacctgcccgga acccaggtggacctgccggggctgtccgagcaggatgcccgggacctgcgcttcggggtg gagcatgaggtagacatcgtgtttgcctcctttgtgcggaaagccagtgacgtggctgcc atccgggaagttctggggccggaaggacggaacatcaagatcattagcaaaatcgagaac cacgaaggcgtgaagaggtttgatgagatcctggaggtgagcgacggcatcatggtggct cgaggagacctgggcatcgagatcccacctgagaaggttttcctggctcagaagatgatg atcggacgctgcaacctggcgggcaagcccgttgtgtgtgccacgcagatgctggagagc atgatcgccaagccccggccgactcgggcagagacgagcgatgtagcgaacgctgtgctg gatggggcggactgcatcatgctgtcgggggagaccgccaagggcaaatttcccgtggag gcagtaaagatgcagcacgcgatcgcccgggaggccgaggctgccatctaccaccggcag ctgtttgaggagctgcgccgggtggcgccactgagccgggatcccactgaggtcactgcc atcggcgcggtggaggcctccttcaagtgctgtgctgctgccattgtcgtgctgagcaag tctggccgctcagcacagctgctgtctcggtaccgacctcgggcaatggtcattgccgtc acccgctctgcccaggctgcccggcaggcccacctgttccgaggggtcttccccgtgctc tacagtaaacctccagaggccatctgggcagacgatgtggatcaccgggtccaatttggc attgagagtggaaagctccatggcttcctccgcgttggggacctggtgattgtggtgaca ggctggcgacctggctctggctacaccaacatcatgcgggtgctgagcgtgtcctga

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