Leopardus geoffroyi (Geoffroy's cat): 123587304
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Entry
123587304 CDS
T10761
Symbol
NOS1
Name
(RefSeq) nitric oxide synthase, brain isoform X1
KO
K13240
nitric-oxide synthase, brain [EC:
1.14.13.39
]
Organism
lgf Leopardus geoffroyi (Geoffroy's cat)
Pathway
lgf00220
Arginine biosynthesis
lgf00330
Arginine and proline metabolism
lgf01100
Metabolic pathways
lgf04020
Calcium signaling pathway
lgf04081
Hormone signaling
lgf04145
Phagosome
lgf04371
Apelin signaling pathway
lgf04713
Circadian entrainment
lgf04730
Long-term depression
lgf04926
Relaxin signaling pathway
lgf04970
Salivary secretion
lgf05010
Alzheimer disease
lgf05014
Amyotrophic lateral sclerosis
lgf05022
Pathways of neurodegeneration - multiple diseases
lgf05410
Hypertrophic cardiomyopathy
lgf05412
Arrhythmogenic right ventricular cardiomyopathy
lgf05414
Dilated cardiomyopathy
lgf05416
Viral myocarditis
Brite
KEGG Orthology (KO) [BR:
lgf00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
123587304 (NOS1)
00330 Arginine and proline metabolism
123587304 (NOS1)
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
123587304 (NOS1)
04020 Calcium signaling pathway
123587304 (NOS1)
09133 Signaling molecules and interaction
04081 Hormone signaling
123587304 (NOS1)
09140 Cellular Processes
09141 Transport and catabolism
04145 Phagosome
123587304 (NOS1)
09150 Organismal Systems
09152 Endocrine system
04926 Relaxin signaling pathway
123587304 (NOS1)
09154 Digestive system
04970 Salivary secretion
123587304 (NOS1)
09156 Nervous system
04730 Long-term depression
123587304 (NOS1)
09159 Environmental adaptation
04713 Circadian entrainment
123587304 (NOS1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
123587304 (NOS1)
05014 Amyotrophic lateral sclerosis
123587304 (NOS1)
05022 Pathways of neurodegeneration - multiple diseases
123587304 (NOS1)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
123587304 (NOS1)
05412 Arrhythmogenic right ventricular cardiomyopathy
123587304 (NOS1)
05414 Dilated cardiomyopathy
123587304 (NOS1)
05416 Viral myocarditis
123587304 (NOS1)
Enzymes [BR:
lgf01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
123587304 (NOS1)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
PDZ
PDZ_6
PDZ_2
Motif
Other DBs
NCBI-GeneID:
123587304
NCBI-ProteinID:
XP_045312880
LinkDB
All DBs
Position
D3:complement(14067979..14252391)
Genome browser
AA seq
1463 aa
AA seq
DB search
MENQVFSVQQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQA
GDIILAVNGQPLVDLSYDSALEVLRGIASETHVVLILRGPEGFTTHLETTFTGDGTPKTI
RVTRPLAPPTTAVDLSHQSSASREHSPAVDRATGPGNGPQHAQDGGQEAGSLPHTKSRAP
GPPGQDSAKKSIQGSQNSDLLKEIEPVLSLLTSGSKGINGGGPSKAETKDAEVQVDRGMD
GKSHKPLPLGVENDRVFSDLWGKGHVPVVLNNPYSEKEQPPASGKQSPTKNGSPSKCPRF
LKVKNWETDVVLTDTLHLKSTLEMGCTEHICMGSIMLPSQQIRRPEDVRTKEQLFPLAKE
FIDQYYSSIKRFGSKAHTERLEEVNKEIETTGTYQLKDTELIYGAKHAWRNASRCVGRIQ
WSKLQVFDARDCTTAHGMFNYICNHIKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLI
RYAGYKQPDGSILGDPANVEFTEICVQQGWKPPRGRFDILPLLLQANGNDPELFQIPPEL
VLEVPIRHPRFEWFKDLGLKWYGLPAVSNMLLEIGGLEFTACPFSGWYMGTEIGVRDYCD
NSRYNILEEVAKNMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIK
HMENEYRCRGGCPADWVWIVPPMSGSVTPVFHQEMLNYRLTPSFEYQPEPWNTHVWKGTN
GTPTKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLCEIFKHA
FDAKVMSMEEYDIVHLEHEALVLVVTSTFGNGDPPENGEKFGCALMEMRHPNSVQEERKY
PEPLRFFPRKGPPLPQGDTEVHGLAAARDSQQRSYKVRFNSVSSYSDSHKSSGDGPDLRD
NFESAGPLANVRFSVFGLGSRAYPHFCAFGHAVDTLLEELGGERILKMREGDELCGQEEA
FRTWAKKVFKAACDVFCVGDDVNIEKANNSLISNDRSWKRDKFRLTYVAEAPELTQGLSN
VHKKRVSAARLLSRQNLQSPKSSRSTIFVRLHTNGNQELQYQPGDHLGVFPGNREDLVNA
LMERLEDAPPVNQLVKVELLVERNTALGVISNWTDEHRLPPCTIFQAFKYYLDITTPPTP
LQLQQFASLATSEKEKQRLLVLSKGLQEYEEWKWGKNPTIVEVLEEFPSIQMPTTLLLTQ
LSLLQPRYYSISSSPDMYPDEVHLTVAVVSYHTRDGEGPIHHGVCSSWLNRIPTDEVVPC
FVRGAPSFHLPRNPQVPCILIGPGTGIAPFRSFWQQRQFDIQHKGMSPCPMVLVFGCRQS
KIDHIYREETLQAKNKGVFRELYTAYSREPDKPKKYVQDILEEHLAEPVYRALKEQGGHI
YVCGDVTMAADVLKAIQRIMTQQGKLSAEDAGVFISRLRDDNRYHEDIFGVTLRTYEVTN
RLRSESIAFIEESKKDTDEVFSS
NT seq
4392 nt
NT seq
+upstream
nt +downstream
nt
atggagaatcaggtgttcagcgttcagcagatccaacccaacgtcatctccgtccgcctc
ttcaagcgcaaggtggggggcctggggttcctggtgaaggagcgggtgagcaagccgccc
gtgatcatctccgacctgattcgggggggtgccgcggagcagagcggcctcatccaggcc
ggtgacatcatccttgcagtcaacggccagcccctggtggacctgagctatgacagcgcc
ctggaggtgctcaggggcatcgcctctgagacccacgtggtcctcattctgaggggcccc
gagggcttcaccactcacctggagaccaccttcaccggggacgggacccccaagaccatc
cgcgtgacgcggcctctggctccccccaccaccgctgtcgatctgtctcaccagtcatcg
gccagcagagagcactcaccggcagtggacagggccacgggtcctggcaatgggccgcag
cacgcccaagacggtgggcaggaagccggctctctcccccataccaagagccgggctccc
gggcccccgggccaggactctgccaagaagagcatccagggcagccagaacagtgatttg
ctcaaagagatagaacctgtactgagccttctcaccagtgggagcaaagggatcaatggc
gggggaccttccaaggcagagacgaaggatgcagaagtccaggtggacagaggtatggat
ggcaagtcacacaagccactgcccttgggcgtggagaatgaccgagtcttcagtgacctg
tgggggaagggccacgtgcctgtcgtcctcaacaacccgtattcggagaaggagcagccc
cctgcctcgggaaaacagtctcctacaaagaacggcagcccctccaagtgcccccgcttc
ctcaaggtcaagaactgggagaccgacgtggtcctcactgacacccttcaccttaagagc
acattggaaatgggctgcaccgagcacatctgtatgggctccatcatgctcccctctcag
cagatacgaaggcctgaagacgtccgcacaaaagaacagctcttccctctcgccaaagag
ttcattgaccagtactactcatcaattaaaaggtttggctccaaagcccacacggagagg
ctggaagaggtgaacaaagagatcgaaaccaccggcacctaccagctcaaagacacggag
ctcatctacggggccaagcatgcctggcggaacgcctcccgctgcgtgggcaggatccag
tggtccaagctgcaggtgttcgatgcccgcgactgcaccacggctcacgggatgttcaac
tacatctgcaaccacatcaagtatgccaccaacaaagggaacctcagatccgccatcacc
atattcccccagaggacggacggcaagcacgatttccgagtctggaactctcagctcatc
cgctatgccggctacaagcagcctgatggctccatcctgggggacccagccaatgtggaa
ttcacagagatctgtgtgcagcagggctggaaacccccaagaggccgcttcgatatcctg
ccactcctgctccaggccaacggcaacgatcccgagctcttccagatccccccagagctg
gtgttggaagtgcccatcaggcaccccaggtttgagtggttcaaggatctgggcctgaag
tggtatggcctccccgctgtgtccaacatgctgctggagattggcggcctggagttcacc
gcctgtcccttcagcggctggtacatgggcacagagattggcgtccgcgactattgtgac
aactctcgatacaacatcctggaggaagtggccaagaacatgaacttggacatgaggaag
acgtcctccctgtggaaggaccaagcactggtggaaatcaacattgctgttctctacagc
ttccagagtgacaaagtgaccattgttgaccaccactctgccaccgagtccttcatcaag
cacatggagaatgaataccgctgccgggggggctgccccgccgactgggtgtggattgtg
ccccccatgtctggcagtgtcacccctgtcttccaccaggagatgctcaactaccgactc
accccgtccttcgaataccagcctgagccttggaacacccacgtctggaaaggcaccaat
ggaacccccacaaagcggcgagccatcggcttcaagaagctggcagaagccgtcaagttc
tcagccaagcttatggggcaggcaatggccaagagggtcaaggcgaccatcctttatgcc
acagagacgggcaagtcgcaggcctatgctaaaaccttgtgtgagatcttcaaacatgcc
tttgatgccaaggtgatgtccatggaagaatatgacattgtacacctggaacatgaagct
ctggtcctagtggttaccagcacttttggcaatggcgaccccccagagaatggggagaaa
ttcggctgtgctttgatggaaatgaggcaccccaactccgtgcaggaggaaaggaagtac
ccggaacccttgcgtttctttccccgtaaagggcctcccctcccccaaggtgacacagaa
gtccatggtctggctgcagcccgtgacagccagcagaggagctacaaggtccgattcaat
agtgtttcctcgtattctgactcccataaatcatcaggcgacgggccagacctcagagac
aactttgagagtgctggacccctggccaacgtgaggttctccgtctttggccttggctcc
cgggcttaccctcatttctgcgcctttggacatgccgtggacaccctcttggaggagctg
ggaggagagaggatcctgaagatgagggagggagacgagctctgtgggcaggaagaggct
ttcaggacctgggccaagaaggtcttcaaggcagcctgcgatgtgttctgcgtgggagat
gacgtcaacattgagaaggcaaacaactccctcatcagcaacgaccgcagctggaagaga
gacaagttccgcctcacctacgtggccgaagctccggaacttacacaaggtctatccaat
gtccacaaaaagcgggtctcggccgctcgactcctcagccgccaaaaccttcagagccct
aaatccagccgatcaacgatcttcgtgcgtctccacaccaatgggaatcaggaactgcag
taccagcctggggaccacctgggcgtcttccctggcaaccgcgaggacctcgtgaacgcc
ctgatggagcggctggaagatgctcccccagtcaaccagctggtgaaggtggaactgctg
gtggagaggaacacggctttgggcgtcatcagtaactggacagatgagcaccgcctcccg
ccctgcaccatcttccaggccttcaagtactacctggacatcaccacgccgcccacgcca
ctgcagctgcagcagtttgcgtccctggccaccagcgagaaagagaagcagcgactgctg
gtcctcagcaagggcttgcaggagtacgaggaatggaaatggggcaagaaccccaccatc
gtggaggtgctggaagagttcccgtccatccagatgcccaccaccctgctcctgacccag
ctgtccctgctgcagcctcgatactattcaatcagttcttccccagacatgtaccctgac
gaggtgcacctcaccgtggccgttgtctcctaccacacccgagatggagaaggaccaatt
caccacggcgtgtgctcctcctggctcaaccggataccgactgacgaagtggtcccctgt
ttcgtgagaggagcacccagcttccacctgccccgaaatccccaagtgccctgtatcctc
attggcccaggcactggcattgcccctttccgaagcttctggcagcagcgacaatttgat
atccagcacaaaggaatgagcccctgccccatggtcctggtgtttgggtgccggcaatcc
aagatagaccacatctacagggaggaaactctacaggccaagaacaagggggtcttcaga
gaactctacacggcctactcgcgggagccagacaaaccaaagaagtacgttcaggacatc
ctggaggagcatttggcagaacctgtgtaccgagccctgaaggagcaagggggccacatt
tacgtctgcggggacgtcaccatggccgccgatgtcctcaaagccatccagcgcatcatg
acccagcaagggaagctctcagcggaggatgctggcgtgttcatcagcaggctgagggat
gacaaccggtaccatgaggatattttcggggtcaccctgcgaacatatgaagtgaccaac
cgccttagatctgaatccattgccttcattgaggagagcaaaaaagacactgatgaagtt
ttcagctcctaa
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