Leopardus geoffroyi (Geoffroy's cat): 123588483
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Entry
123588483 CDS
T10761
Symbol
LAMA1
Name
(RefSeq) laminin subunit alpha-1 isoform X1
KO
K05637
laminin, alpha 1/2
Organism
lgf Leopardus geoffroyi (Geoffroy's cat)
Pathway
lgf04151
PI3K-Akt signaling pathway
lgf04510
Focal adhesion
lgf04512
ECM-receptor interaction
lgf04820
Cytoskeleton in muscle cells
lgf05145
Toxoplasmosis
lgf05146
Amoebiasis
lgf05165
Human papillomavirus infection
lgf05200
Pathways in cancer
lgf05222
Small cell lung cancer
lgf05410
Hypertrophic cardiomyopathy
lgf05412
Arrhythmogenic right ventricular cardiomyopathy
lgf05414
Dilated cardiomyopathy
lgf05416
Viral myocarditis
Brite
KEGG Orthology (KO) [BR:
lgf00001
]
09130 Environmental Information Processing
09132 Signal transduction
04151 PI3K-Akt signaling pathway
123588483 (LAMA1)
09133 Signaling molecules and interaction
04512 ECM-receptor interaction
123588483 (LAMA1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
123588483 (LAMA1)
09142 Cell motility
04820 Cytoskeleton in muscle cells
123588483 (LAMA1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
123588483 (LAMA1)
09162 Cancer: specific types
05222 Small cell lung cancer
123588483 (LAMA1)
09172 Infectious disease: viral
05165 Human papillomavirus infection
123588483 (LAMA1)
09174 Infectious disease: parasitic
05146 Amoebiasis
123588483 (LAMA1)
05145 Toxoplasmosis
123588483 (LAMA1)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
123588483 (LAMA1)
05412 Arrhythmogenic right ventricular cardiomyopathy
123588483 (LAMA1)
05414 Dilated cardiomyopathy
123588483 (LAMA1)
05416 Viral myocarditis
123588483 (LAMA1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Laminin_G_1
EGF_laminin
Laminin_G_2
Laminin_B
Laminin_N
Laminin_I
EGF_LMN_ATRN
Laminin_II
Laminin_G_3
DUF5994
HAD_2
Motif
Other DBs
NCBI-GeneID:
123588483
NCBI-ProteinID:
XP_045315510
LinkDB
All DBs
Position
D3:36910878..37079355
Genome browser
AA seq
3085 aa
AA seq
DB search
MRGGGAGVALLASLLWVAARCQQRGLFPAILNLASNAHISTNATCGERGPEMSCKLVEHV
PGRPVRNAQCRICDADSANPKERHPISHAIDGTNNWWQSPSIQNGREYHWVTITLDLRQV
FQVAYVIIKAANAPRPGNWILERSLDGTKFSPWQYYAVSDTECLTRYNITPRRGPPTYRA
DDEVICTSYYSRLVPLEHGEIHTSLINGRPSADDLSPKLLDFTSARYIRLRLQRIRTLNA
DLMTLSHRDPKDLDPIVTRRYYYSIKDISVGGMCICYGHASSCPWDETTKKLQCQCEHNT
CGESCNRCCPGYHQQPWRPGTISSGNTCEKCNCHNKAQDCYYDGNVANQRRSLNTAGQFR
GGGVCISCLQNTMGINCETCIDGYFRPHDVSPYDDNPCRPCDCDPFGSLSSVCIKDKPQS
GLHKGKWPGQCPCKEGYAGEKCDHCQFGFKAYPACVRCECSRAGSVNEDPCSEPCLCKEN
VEGENCDLCKPGFYNLKERNPEGCSECFCFGVSDVCDSLSWSISQVKDMSGWLVTDLISP
SKIPSQQDALGGRHQISINNTVATQRLTSKYYWSAPEAYLGNKLTAFGGFLKYTVSYDIP
VETVDGDLMSHTDVIIKGNGLTLSTQAEGLSLQPYEEYLNVVRLVPENFRDFNNKKEIDR
DQLMTVLANVTHLLIRANYNSAKMALYRLDSVSLDTASPNVIDLALATEVEHCECPQGYA
GISCESCLPGYYRVDGILFGGICQPCECHGHAAECDIHGVCFACKHNTTGDHCEQCAPGF
YGLPSRGTPRDCQQCACPLSTASNNFSPTCHLEDGDEVVCDQCAPGYSGAWCERCADGYY
GNPTVPGESCVPCDCSGNVDPLEAGHCDSVTGECLKCIGNTAGAHCERCADGFYGDAVTA
KNCRACECHGKGSLSGVCHLETGVCDCKPHVTGQQCDRCSHGYYGLDTGLGCLPCNCSTP
GSLSDDCTEEGRCHCVPGVAGEKCDRCARGFYAFQDGGCTPCDCAHTQHTCHPESGQCIC
PPHTRGASCDECEDGYWGRDPELGCQACNCSAVGSASHQCDVLTGRCRCKPAFGGPSCHQ
CSLGYRDFPDCVPCDCDPRGTSADTCDEEQSLCSCAEETGICSCKENVFGLQCSECRAGT
YALRADDPLGCTPCFCFGLSQVCSELEGYVRTPITLGSGQPLLRVVSQSNLRGTTQGVYY
QAPDVLLDAVTVRQHIHTEPFYWRLPERFQGDQLLAYGGRLKYSVAFYSSNGMGTFNLEP
QVLIKGGRTRKQVIYVDVPAPENGVRQDQEVGMKENFWRYFNSVSEKPVTRSDFMSVLSN
IEYILIKASYGQGLQQSRISNISMEVGKKADKLRPGQKAASRLEKCLCPPGTAGFSCQDC
APGYHRGELPQGGGRGPRPLLAPCVPCNCNNHSDACDPETGKCLNCSHSTTGDHCDLCAP
GYFGKVTGSASDCSVCACPRSHPASFSPTCVLEGDHDFRCDACILGYEGQYCERCSSGYH
GNPRALGGTCQRCDCSPSGSVHGDCDRRSGQCVCRPGATGLRCEECEPRHILLESDCVSC
DDECVGVLLNDLDNIGDAILSVNLTGVIPVPSGILSNLENTTKYLREALLKENTRKDLAE
DRLEDVAKQTDHLLRELTRVLTSSQHVTRATEGILDKSQDLMTFTEKLQRTIQEIIEKAA
TLNQTLDEDFQLPSSTLQNMQKNITSLLEVIQKRHFVQLQQKAILELKAAEDLLSQIQNN
YQKPQKELEVLKEAASSLLSKRSSELQAARDLVREAEVKNQESARLLHIVSANLREFNDK
TVRVQQEQNLTSTLIARGRRLLDAVTAPADAVGDALAQLERHRDELLLWTAKIRRHVDDL
VMQMSQRRALDLVYRAEDHAAELQRLAGALDSGLGSVRHVSLNATSATHVHSNIRSMIEE
SEKVAKDALKIVTTASLFSESLAPNGKVALQRSSRFLKEGNSLSRKHQGITLELSKLKNT
ANRFQENAHTITRRTNESLSILRAFPEGVRDKGAKIKELASSANRSAASTLKKVVGLSKE
LLNTSTGLSRVNAALQETNKLLQDSSMTTLLAGRRVKDAETQASLLFDRLKPLKTLEENL
SRNLSEIKLLISQARKQAASIKVAVSADRDCVRAYQPQISSTNYNTLTLNVKTSEPDNLL
FYLGSSTSSDFLAVEMRRGKVAFLWDMGSGSTRLEFPDFRADDNKWHSIYVTRFGNIGSL
SVKEMSATQKPSTKTSKSPGTAKVLDINNSTLMFVGGLGGQIKKSPAVKVTHFKGCMGEA
FLNGQSIGLWNYVEREGKCHGCFGSPQNEDSSFHFDGSGYSVVEKTLRATVTQIIMLFST
FSPNGLLLYLASNGTKDFVSIELVRGRVRVTVDLGSGPLALITDRRYNNGTWYKIAFQRN
RKQGLLAVIDAYNTSYKETKQGETPGASSDLNRLDKDPIYVGGLPRSRVVRKGVTSKSYV
GCIKNLEISRSTFDLLRNSYGVRKGCILEPIRTVSFLKGGYVELSPRSLLPESELLATFA
TKNSSGIILAALGRHGEKQGHRQAHGQPSQPFFSIMLIDGHIEVHVNSGDGANLRRAVLH
APNGTYGDGQEHSISLMRTGSVITVQMDETNPVEMKLGPSAESRTINVSSLYIGGVPEGE
GTSVLKMGRSFHGCIKNLIFNMEHLDFTSAVGYEQVDLDTCLLSERPKLALHGEDSELPP
EPQPLPSLGQCAVDRAPEYIPNAHQFGLMQSSHFVLPFNQLAVRKRLSVQLSIRTFASSG
LIYYMAHQNQVDYATLQLHGGHLHFMFDLGKGRTKVSHPAVISDGRWHTVKTEHFKRKGF
MTVDGQESPTVTAVGDGTMLDVEGKLYLGGLPSEYRARNIGNITHSVPACIGEVILNGKQ
LDKSSPVSAFAVSRCYAVAQEGTFFEGSGYAALVKEGYKVRSDVNITLEFRTTSENGVLL
GISSAKVDAIGLEIVNGKILFHVNNGAGRITATYKPKATSTLCDGRWHTLQAQKSKHRLV
LIVDGNAAHAESPHTQSTSADTNNPIYVGGYPADVKQNCLSSQTSFRGCLRKLTLIKGPQ
VQSYDFSRAFDLQGVFPHSCPGSEP
NT seq
9258 nt
NT seq
+upstream
nt +downstream
nt
atgcgcggcggtggcgcgggggtcgcgctcctggcctcgctgctctgggtcgccgcgcgg
tgccagcagagagggctgtttcctgccattctcaatcttgccagcaacgcgcacatcagc
accaatgccacctgtggggagcgggggcccgagatgtcctgcaagcttgtggagcacgtg
cccggtcgacccgtgcgcaacgcacagtgccggatctgcgacgcggacagcgccaacccc
aaagaacgccacccaatatcccatgcaatcgatgggaccaacaactggtggcaaagcccc
agtattcaaaacgggagagaatatcactgggtcacaatcactctggacttaagacaggtc
tttcaagttgcctacgtcatcatcaaagctgctaatgcccctcgacccggaaactggatt
ttggagcgttctctggatggcaccaagttcagcccctggcagtactatgcagtcagtgac
acggagtgtttgacccgttacaatatcactccaagacgggggccgcccacttacagggct
gatgacgaagtgatctgcacctcctactattccagactggtgccgcttgaacacggagag
attcatacatcgctaatcaacggcagaccgagcgctgatgatctctcacccaagctgttg
gattttacttctgcacgatatatccgccttcgcttacagcgtatcagaaccctcaatgcc
gatcttatgaccctcagccaccgagaccctaaagacctcgatcccatcgttacaagacga
tattactattcaatcaaagacatttctgttggcggaatgtgtatttgttatggccatgcc
agtagctgcccatgggatgaaactacaaagaagcttcagtgtcagtgtgaacataatacc
tgtggagagagctgcaataggtgttgtccgggataccaccagcagccgtggcggcccggc
accatttcttccggtaacacgtgtgaaaagtgtaattgtcacaataaagcccaagactgt
tactatgatggaaatgttgcaaatcagaggagaagcttgaataccgcgggacagttcaga
ggaggcggggtgtgcatcagctgcctgcagaacaccatgggaatcaactgtgaaacctgt
atcgatggatatttcagaccacacgacgtatctccttatgatgacaacccttgtcgtccc
tgtgactgtgacccttttgggtccctcagttcggtctgtattaaggataagcctcaatct
ggcttacacaaagggaagtggccaggtcaatgtccatgcaaggaaggctacgcaggagaa
aaatgtgatcactgccaatttggttttaaggcttacccagcctgtgtccgctgtgagtgt
agccgggctggcagtgtgaacgaggacccatgctcagagccctgtctctgcaaggaaaat
gttgaaggggaaaattgtgacctctgcaagccaggattctataacttgaaggagagaaac
cctgagggctgctcggagtgcttctgctttggcgtttctgatgtctgcgacagcctttct
tggtccatcagtcaggtgaaagacatgtctgggtggcttgtcaccgacctgatcagtccg
agcaagatcccatctcagcaagatgcactgggtgggcgtcatcagattagcatcaacaac
acggtggccacgcagaggctgacttccaagtattactggtcggcaccggaggcctacctc
ggaaataagctgactgctttcggtggattcctgaagtacacagtgtcctatgatattcca
gtggagacagtggatggcgacctcatgtcccacaccgatgtcatcatcaagggaaatgga
ctcactttaagcacccaggccgagggcctgtcattacagccctatgaagagtatttaaac
gtggtcagacttgtgccagagaacttccgagattttaataacaaaaaggagatagatcgt
gaccaactgatgactgtccttgccaatgtgacacatctcctgatcagagccaactataat
tctgcaaaaatggctctttacaggttggattctgtctctttggacacagccagccctaac
gttatagacctggcactggccacggaggtggagcactgcgaatgtccccaaggctatgca
gggatctcctgtgagtcctgtctccctggctattatcgtgtggatggaatactctttgga
ggaatttgtcaaccctgtgaatgccatggccatgcagctgaatgcgatatccacggcgtt
tgctttgcgtgcaagcacaacaccaccggggaccactgtgagcagtgcgcgcccggcttc
tacgggctgccttcccgagggactcctagggactgccagcagtgtgcctgccccctctcc
acagcctccaacaatttcagccccacctgccacctagaagatggggacgaagtggtctgt
gaccagtgtgcaccgggatactcgggagcttggtgcgagagatgcgcagacggttactat
ggaaacccaacagtgcccggggaatcctgtgttccctgcgactgcagcggcaatgtggat
cccttagaggccggtcactgtgactccgtcaccggagagtgcctgaaatgcattgggaac
acggctggtgcccactgtgagaggtgtgcggacggcttctatggggatgccgtgactgct
aaaaattgccgcgcctgtgaatgccatggaaaaggctccctttctggtgtctgccatctg
gagactggagtctgtgactgcaaaccgcacgtgactggacagcagtgtgaccggtgctcg
catggctattatgggctggacacagggcttgggtgcttgccctgtaactgcagcacgcca
ggctccctgtcggatgactgcacggaggaaggccgatgtcactgtgtgccaggtgtggct
ggggaaaagtgcgacaggtgtgcacgcggcttctatgcgttccaggacggcggctgtaca
ccctgtgactgcgcccacacgcagcacacttgtcacccggaatcggggcagtgcatctgc
cctcctcatactcggggcgcatcctgtgacgaatgtgaggacggatactggggccgcgac
ccagagctcggatgccaggcctgcaattgcagtgctgttgggtcagccagtcatcagtgc
gatgtgctcactggccgttgccgatgtaagccagcgttcggtggaccgagctgccaccag
tgctccctggggtacagagactttccagactgcgtgccctgtgactgtgacccaagaggg
acctcggcagacacctgtgatgaggaacagagtctttgcagctgtgcagaggaaaccggt
atctgctcttgcaaggaaaatgtgtttggcctgcagtgcagcgagtgtcgagccggcacc
tatgctctccgcgccgacgaccctctggggtgcaccccctgcttctgcttcgggctgtca
caagtctgctcagagctcgagggttatgtgaggaccccgataaccctgggctcgggtcag
ccgctcctgcgtgtggtttctcagagcaacctcaggggcacgacccagggggtgtattac
caggctcctgatgtcctcctggatgccgtgactgtcaggcagcatattcacacggagccg
ttctactggagactgccagagcggttccagggagaccagcttctggcctacggtggcaga
ctgaagtacagcgtggccttctattcttccaatggcatgggcaccttcaaccttgaaccc
caagtgctcatcaaaggaggccggacaagaaagcaagtcatctacgtggatgtgccagcc
ccggagaatggcgtgcgacaagaccaagaagtgggaatgaaagagaatttttggagatat
tttaactctgtttctgaaaaacctgtcacacgctccgattttatgtctgttcttagcaac
attgagtacatcctcatcaaagcatcttatggtcagggattacagcaaagcagaatctca
aatatttccatggaggttggcaaaaaagcggacaagttgcggccgggacagaaggcggca
tcccgtttagagaagtgtctctgtcctcctggcacggctgggttctcctgtcaggactgc
gcacctggttaccacagaggggagctgccgcaaggtggtggccgaggaccccgccctctg
ctcgctccctgtgtgccctgcaattgcaacaaccacagcgatgcctgtgaccccgaaact
gggaagtgcctgaactgcagccatagcaccactggtgaccactgtgacttgtgtgctcct
gggtacttcgggaaggtgactggctcagccagcgactgctctgtgtgcgcctgtcctcgc
agccaccctgccagttttagtcccacttgtgtcttggaaggtgatcacgatttccgctgt
gatgcctgcattctgggctacgaaggacagtactgtgaaaggtgctcctcaggctatcac
gggaaccctcgagcgctgggtggcacttgccagcggtgtgactgcagccccagtggctct
gtccacggtgactgtgaccgcaggtccgggcagtgtgtctgcaggccaggcgccacaggg
ctccgatgcgaggaatgcgaaccgaggcacattctgctggaaagcgattgtgtttcttgt
gatgatgaatgtgtgggtgtgctgctaaatgacttagataatattggggacgccatcctt
tccgtgaacctcactggcgttatccctgtcccatctggaattttgtcaaacctggaaaat
acaacgaaatatctccgggaagctttattaaaagaaaatacacgtaaggacctggcagaa
gatcggcttgaagatgttgcaaaacaaacagaccacctgctaagggagctcactagagtg
ttaacgagtagccaacatgtaaccagggcgactgaaggaatccttgacaagagccaagac
ctcatgacatttactgagaagctgcagagaactatccaagagattattgaaaaagcagca
actctaaatcagaccttggatgaagacttccaactacccagttctactcttcagaatatg
caaaagaatattacatctttgctagaagtcatacagaaaaggcatttcgtgcagttgcaa
cagaaagccatactggaactcaaggctgctgaagatttattgtcacagattcagaataat
taccagaagccacagaaagagttggaggtattaaaagaagcagcaagcagccttctttca
aaacgcagcagtgaactgcaggcagcgagggaccttgtgagggaagcagaggtgaagaac
caggagagcgcccgcctgctgcacattgtcagcgccaacctgcgagaatttaacgataag
acggtgcgtgttcagcaagagcaaaacttgacctccacgctgattgccagagggagaaga
ttgctagacgctgtcactgcacctgcagatgctgtaggagatgctctagcacagttagag
cgtcaccgagatgagctacttttatggactgccaaaatcaggcgccatgtagatgatctg
gtcatgcagatgtcccaaaggagagctcttgaccttgtctacagagcagaggaccacgca
gctgaactccagagactagcaggtgctctggacagtggccttggcagtgttagacatgtg
tccctgaatgccaccagtgcaacccacgtccattccaacattcggagcatgattgaagaa
tcagagaaagtggcaaaagatgctctcaagatcgtgacaacggcgagtctgttctcagaa
tcccttgctcccaatgggaaagtggctctccagcgcagttccagatttctaaaagaaggc
aacagcctgagcagaaagcatcaaggtatcacattggaactgagtaaattgaaaaataca
gcaaacagatttcaagagaatgctcatacaattactaggcggaccaatgaatcactctcc
atccttagagcattccctgaaggtgtcagagacaaaggagccaaaatcaaagagctggcc
tcatctgcaaatcggagcgctgcaagcaccctaaagaaggttgtaggattgagcaaggag
ctgttgaatacatcaactggcttgtccagggttaatgccgccttacaagaaacaaacaaa
cttctgcaggactcttcaatgaccactctgctagctggaagaagagttaaagatgcagaa
acacaagccagccttttatttgatcggttgaagcctttgaagacattagaagagaacctg
agcagaaacctatcagaaatcaaactgctgatcagccaggcccggaaacaagcagcttct
attaaagtcgctgtgtctgcagacagagattgtgtccgggcctaccagcctcagatttct
tctactaactataacaccttaacactaaatgttaagacaagtgaacccgataaccttctc
ttctacctcgggagcagcaccagttctgatttcctggcagtggagatgcggcgagggaag
gtggcctttctctgggatatgggctccgggtctacacggttggaatttccagacttccga
gctgatgacaacaaatggcacagtatctatgtaaccagatttggaaacattggttcattg
agtgtaaaggaaatgagtgcaactcaaaagccatcaacaaaaacaagtaaatcccctgga
acagctaaagttctggatataaacaattcaacactaatgtttgttggagggcttggagga
cagatcaagaagtctcctgctgtgaaggttactcattttaaaggctgcatgggagaggcc
ttcttgaacggacagtccatcggcctgtggaactatgttgaacgggagggcaagtgccac
ggctgcttcggaagcccccagaacgaagactcgtccttccattttgatgggagtggttat
tcggttgtggagaagacgctccgggctaccgtgactcagataattatgctttttagtacc
ttttcacccaacgggcttcttctctaccttgcttcaaatggcactaaagactttgtatcc
atcgagctggtgcgtggcagagttagagttacagttgacctgggttcagggcctcttgct
cttattacagacagacgctataacaacggaacctggtataaaattgccttccagagaaac
cgaaagcaaggactcctagcagttattgatgcatataacaccagttataaagaaacgaag
caaggtgaaactccgggagcatcttctgacctcaatcgtctagataaagatccaatttat
gtgggtggattacctaggtcaagagttgtaaggaaaggtgtcaccagcaaaagctatgtg
ggctgtatcaaaaacctggaaatatccagatcaacctttgatttactcagaaattcctat
ggagtgagaaaaggctgtatactggagcctatccgaactgttagcttcttgaaaggtggc
tacgttgaattgtcacccaggtctttgttgccagaatcggaactgttggcaacatttgcc
accaagaacagcagtggcatcatcctggctgccctgggcaggcatggggagaagcagggt
catcggcaggcccacgggcaaccttcccagcccttcttttccatcatgctgattgacggc
cacattgaagtgcacgttaactctggggacggagcaaacctgagaagagctgtcctgcat
gctcccaacggcacatatggtgacgggcaagagcattccatctctctgatgaggactggg
agcgttatcactgtccaaatggatgagacaaatcctgtagaaatgaagttgggcccatca
gcagaaagcaggacaataaatgtatccagcctgtacatagggggagttccagagggtgag
gggacatcagtgctcaagatgggaagatcatttcacggctgtatcaaaaacctgatcttt
aacatggaacatttggatttcacgagtgcggttggttatgaacaagtagatttggacacc
tgcttgctttcagaaaggccgaagctggctcttcatggagaggacagcgagctcccgcca
gagcctcagcctttaccaagtctagggcagtgtgccgtggacagagccccagagtacatc
cccaacgctcaccagtttggcctcatgcaaagcagccattttgtgttgcccttcaatcag
ctggctgtcagaaagaggctctcagttcagctaagtatccggacatttgcctccagcggt
ctgatttactacatggctcatcagaaccaagttgattatgccacgctccagctgcatggg
ggccaccttcacttcatgtttgatcttgggaaaggcagaacaaaggtctcccaccctgca
gtgatcagtgatggcaggtggcacacggtcaagacagagcactttaaaagaaagggcttc
atgacagttgatggccaggaatcccccacggtgacagctgtgggagatggtaccatgttg
gatgtggaaggaaagctgtacctaggaggtcttccctctgagtacagagccaggaacatt
ggaaacatcacccacagtgtccccgcctgcattggggaggtgatactgaatggcaaacag
ctggacaaaagcagcccagtgtctgcatttgcagtaagcaggtgctatgcagtggcccag
gaaggaacgttctttgaaggcagtggatacgcagctcttgtcaaggaaggctacaaagtc
cgatcagatgtaaatataacactggaatttcgtaccacctctgagaatggtgtcctcctg
gggatcagcagcgccaaagtagatgccatcggattagagattgtgaatggcaagatcttg
tttcatgttaacaatggtgctggtcggataacggccacatataaacccaaagctaccagt
actctgtgcgatggaagatggcacacacttcaagctcagaaaagcaaacaccgcttggtt
ctgattgttgatgggaatgcagctcacgctgaaagtccacacacccagtccacctcagca
gacaccaacaatcccatttatgtgggcggctaccctgctgacgtaaagcaaaactgcctg
agcagccagacctccttccgggggtgcttgagaaagctcactctgattaagggcccacaa
gtgcaatcctatgacttcagcagagcttttgatctacaaggagttttccctcattcctgt
cctgggtctgaaccctga
DBGET
integrated database retrieval system
