KEGG   Leopardus geoffroyi (Geoffroy's cat): 123589226
Entry
123589226         CDS       T10761                                 
Symbol
RAC1
Name
(RefSeq) ras-related C3 botulinum toxin substrate 1 isoform X1
  KO
K04392  Ras-related C3 botulinum toxin substrate 1
Organism
lgf  Leopardus geoffroyi (Geoffroy's cat)
Pathway
lgf04010  MAPK signaling pathway
lgf04014  Ras signaling pathway
lgf04015  Rap1 signaling pathway
lgf04024  cAMP signaling pathway
lgf04062  Chemokine signaling pathway
lgf04071  Sphingolipid signaling pathway
lgf04145  Phagosome
lgf04148  Efferocytosis
lgf04151  PI3K-Akt signaling pathway
lgf04310  Wnt signaling pathway
lgf04360  Axon guidance
lgf04370  VEGF signaling pathway
lgf04380  Osteoclast differentiation
lgf04510  Focal adhesion
lgf04520  Adherens junction
lgf04530  Tight junction
lgf04613  Neutrophil extracellular trap formation
lgf04620  Toll-like receptor signaling pathway
lgf04650  Natural killer cell mediated cytotoxicity
lgf04662  B cell receptor signaling pathway
lgf04664  Fc epsilon RI signaling pathway
lgf04666  Fc gamma R-mediated phagocytosis
lgf04670  Leukocyte transendothelial migration
lgf04722  Neurotrophin signaling pathway
lgf04810  Regulation of actin cytoskeleton
lgf04932  Non-alcoholic fatty liver disease
lgf04933  AGE-RAGE signaling pathway in diabetic complications
lgf04972  Pancreatic secretion
lgf05014  Amyotrophic lateral sclerosis
lgf05020  Prion disease
lgf05022  Pathways of neurodegeneration - multiple diseases
lgf05100  Bacterial invasion of epithelial cells
lgf05132  Salmonella infection
lgf05135  Yersinia infection
lgf05163  Human cytomegalovirus infection
lgf05167  Kaposi sarcoma-associated herpesvirus infection
lgf05169  Epstein-Barr virus infection
lgf05170  Human immunodeficiency virus 1 infection
lgf05200  Pathways in cancer
lgf05203  Viral carcinogenesis
lgf05205  Proteoglycans in cancer
lgf05208  Chemical carcinogenesis - reactive oxygen species
lgf05210  Colorectal cancer
lgf05211  Renal cell carcinoma
lgf05212  Pancreatic cancer
lgf05231  Choline metabolism in cancer
lgf05415  Diabetic cardiomyopathy
lgf05416  Viral myocarditis
lgf05417  Lipid and atherosclerosis
lgf05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:lgf00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    123589226 (RAC1)
   04014 Ras signaling pathway
    123589226 (RAC1)
   04015 Rap1 signaling pathway
    123589226 (RAC1)
   04310 Wnt signaling pathway
    123589226 (RAC1)
   04370 VEGF signaling pathway
    123589226 (RAC1)
   04071 Sphingolipid signaling pathway
    123589226 (RAC1)
   04024 cAMP signaling pathway
    123589226 (RAC1)
   04151 PI3K-Akt signaling pathway
    123589226 (RAC1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    123589226 (RAC1)
   04148 Efferocytosis
    123589226 (RAC1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    123589226 (RAC1)
   04520 Adherens junction
    123589226 (RAC1)
   04530 Tight junction
    123589226 (RAC1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    123589226 (RAC1)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    123589226 (RAC1)
   04620 Toll-like receptor signaling pathway
    123589226 (RAC1)
   04650 Natural killer cell mediated cytotoxicity
    123589226 (RAC1)
   04662 B cell receptor signaling pathway
    123589226 (RAC1)
   04664 Fc epsilon RI signaling pathway
    123589226 (RAC1)
   04666 Fc gamma R-mediated phagocytosis
    123589226 (RAC1)
   04670 Leukocyte transendothelial migration
    123589226 (RAC1)
   04062 Chemokine signaling pathway
    123589226 (RAC1)
  09154 Digestive system
   04972 Pancreatic secretion
    123589226 (RAC1)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    123589226 (RAC1)
  09158 Development and regeneration
   04360 Axon guidance
    123589226 (RAC1)
   04380 Osteoclast differentiation
    123589226 (RAC1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    123589226 (RAC1)
   05205 Proteoglycans in cancer
    123589226 (RAC1)
   05208 Chemical carcinogenesis - reactive oxygen species
    123589226 (RAC1)
   05203 Viral carcinogenesis
    123589226 (RAC1)
   05231 Choline metabolism in cancer
    123589226 (RAC1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    123589226 (RAC1)
   05212 Pancreatic cancer
    123589226 (RAC1)
   05211 Renal cell carcinoma
    123589226 (RAC1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    123589226 (RAC1)
   05163 Human cytomegalovirus infection
    123589226 (RAC1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    123589226 (RAC1)
   05169 Epstein-Barr virus infection
    123589226 (RAC1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    123589226 (RAC1)
   05135 Yersinia infection
    123589226 (RAC1)
   05100 Bacterial invasion of epithelial cells
    123589226 (RAC1)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    123589226 (RAC1)
   05020 Prion disease
    123589226 (RAC1)
   05022 Pathways of neurodegeneration - multiple diseases
    123589226 (RAC1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    123589226 (RAC1)
   05418 Fluid shear stress and atherosclerosis
    123589226 (RAC1)
   05415 Diabetic cardiomyopathy
    123589226 (RAC1)
   05416 Viral myocarditis
    123589226 (RAC1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    123589226 (RAC1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    123589226 (RAC1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:lgf04131]
    123589226 (RAC1)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:lgf04147]
    123589226 (RAC1)
   04031 GTP-binding proteins [BR:lgf04031]
    123589226 (RAC1)
Membrane trafficking [BR:lgf04131]
 Exocytosis
  Small GTPases and associated proteins
   Rho GTPases
    123589226 (RAC1)
 Endocytosis
  Lipid raft mediated endocytosis
   Arf6-dependent endocytosis
    123589226 (RAC1)
  Macropinocytosis
   Ras GTPases
    123589226 (RAC1)
 Others
  NADPH oxidases (Nox) and associated proteins
   Nox associated proteins
    123589226 (RAC1)
Exosome [BR:lgf04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   123589226 (RAC1)
  Exosomal proteins of other body fluids (saliva and urine)
   123589226 (RAC1)
  Exosomal proteins of colorectal cancer cells
   123589226 (RAC1)
  Exosomal proteins of bladder cancer cells
   123589226 (RAC1)
GTP-binding proteins [BR:lgf04031]
 Small (monomeric) G-proteins
  Rho Family
   Rac/Cdc42 [OT]
    123589226 (RAC1)
SSDB
Motif
Pfam: Ras Roc Arf CagD
Other DBs
NCBI-GeneID: 123589226
NCBI-ProteinID: XP_045316965
LinkDB
Position
E3:complement(4775778..4800783)
AA seq 211 aa
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG
QEDYDRLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEV
RHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALT
QRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL
NT seq 636 nt   +upstreamnt  +downstreamnt
atgcaggccatcaagtgtgtggtggtgggagacggagccgtaggtaaaacgtgcctactg
atcagttacacaaccaatgcgtttcctggagaatatatccccactgtctttgacaactac
tctgccaatgttatggtggatggaaaaccggtgaatctgggcttatgggatacagctgga
caagaagattatgacagattacgtcccttatcctatccgcaaacagttggagaaacgtat
ggtaaggatataacctccaggggcaaagacaagccgattgccgatgtattcttaatttgc
ttttctcttgtgagtcctgcgtcatttgaaaatgttcgagcaaagtggtaccctgaagtg
cgacaccactgtcccaacacccccatcatcttggtgggaactaaacttgacctcagggac
gacaaagacacgattgagaaactgaaggagaaaaagctgactcccatcacctacccgcag
ggtttggccatggcgaaggagatcggtgctgtaaaatacctggagtgctcggcgctcacg
cagcgaggcctcaagacagtgtttgatgaagctattcgagcggttctctgcccccctccc
gtcaagaagaggaagagaaaatgcctgctgttgtaa

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