Leopardus geoffroyi (Geoffroy's cat): 123589548
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Entry
123589548 CDS
T10761
Symbol
ATP2A1
Name
(RefSeq) sarcoplasmic/endoplasmic reticulum calcium ATPase 1 isoform X1
KO
K05853
P-type Ca2+ transporter type 2A [EC:
7.2.2.10
]
Organism
lgf Leopardus geoffroyi (Geoffroy's cat)
Pathway
lgf04020
Calcium signaling pathway
lgf04022
cGMP-PKG signaling pathway
lgf04024
cAMP signaling pathway
lgf04148
Efferocytosis
lgf04260
Cardiac muscle contraction
lgf04261
Adrenergic signaling in cardiomyocytes
lgf04380
Osteoclast differentiation
lgf04919
Thyroid hormone signaling pathway
lgf04972
Pancreatic secretion
lgf05010
Alzheimer disease
lgf05017
Spinocerebellar ataxia
lgf05022
Pathways of neurodegeneration - multiple diseases
lgf05410
Hypertrophic cardiomyopathy
lgf05412
Arrhythmogenic right ventricular cardiomyopathy
lgf05414
Dilated cardiomyopathy
lgf05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
lgf00001
]
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
123589548 (ATP2A1)
04024 cAMP signaling pathway
123589548 (ATP2A1)
04022 cGMP-PKG signaling pathway
123589548 (ATP2A1)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
123589548 (ATP2A1)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
123589548 (ATP2A1)
09153 Circulatory system
04260 Cardiac muscle contraction
123589548 (ATP2A1)
04261 Adrenergic signaling in cardiomyocytes
123589548 (ATP2A1)
09154 Digestive system
04972 Pancreatic secretion
123589548 (ATP2A1)
09158 Development and regeneration
04380 Osteoclast differentiation
123589548 (ATP2A1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
123589548 (ATP2A1)
05017 Spinocerebellar ataxia
123589548 (ATP2A1)
05022 Pathways of neurodegeneration - multiple diseases
123589548 (ATP2A1)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
123589548 (ATP2A1)
05412 Arrhythmogenic right ventricular cardiomyopathy
123589548 (ATP2A1)
05414 Dilated cardiomyopathy
123589548 (ATP2A1)
05415 Diabetic cardiomyopathy
123589548 (ATP2A1)
Enzymes [BR:
lgf01000
]
7. Translocases
7.2 Catalysing the translocation of inorganic cations
7.2.2 Linked to the hydrolysis of a nucleoside triphosphate
7.2.2.10 P-type Ca2+ transporter
123589548 (ATP2A1)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1-E2_ATPase
Cation_ATPase_C
Cation_ATPase
Cation_ATPase_N
Hydrolase
Hydrolase_3
HAD
Motif
Other DBs
NCBI-GeneID:
123589548
NCBI-ProteinID:
XP_045317756
LinkDB
All DBs
Position
E3:19304310..19319927
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AA seq
1000 aa
AA seq
DB search
MEAAHSKTTEECLAYFGVSETTGLTPDQVKRHLEKYGPNELPAEEGKSLWELVIEQFEDL
LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK
EYEPEMGKVYRADRKTVQRIKARDIVPGDIVEVAVGDKVPADIRILSIKSTTLRVDQSIL
TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVSTEIGKIRDQMA
ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWLRGAIYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCKMFIVDKVDGNICVLNEFSITGSTYAPEGEVLKNDKPVRSGQYDGLVELATICALC
NDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFSTDVRSLSKVERANACNSVIRQLMK
KEFTLEFSRDRKSMSVYCSPAKSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPITGPV
KDKILSVIKEWGTGRDTLRCLALATRDTPPKREEMILDDSARFMEYETDLTFVGVVGMLD
PPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDDL
PLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAMG
SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL
GLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAIG
GYVGAATVGAAAWWFLYADDGPHVTYSQLTHFMQCNEENPAFEGLDCEVFEAPQPMTMAL
SVLVTIEMCNALNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLRA
LDCTQWLMVLKISFPVILLDELLKFIARNYLEDPEDERRK
NT seq
3003 nt
NT seq
+upstream
nt +downstream
nt
atggaggctgcacactccaagaccacagaagaatgtctggcctattttggggtgagcgag
actacaggcctgacgccggaccaagtgaagcggcacctagagaaatacggccccaatgag
ctccctgctgaggaagggaagtccctgtgggagttggtgatagagcagtttgaagacctc
ctggtgcggatccttctcctggccgcctgcatttccttcgtgctggcctggttcgaggaa
ggtgaagaaaccatcactgcctttgttgaaccctttgtcatcctcttgatcctcattgcc
aatgccatcgtgggggtttggcaggagcgtaatgcagagaatgccattgaggctctgaag
gaatatgaacccgagatggggaaagtctaccgggctgaccgcaagacagtacagaggatc
aaggctcgggatattgtccccggggacattgtggaggtggctgtgggcgacaaagtgcct
gccgatatccggatcctgtccatcaaatccaccaccctccgggttgaccagtccatcctg
acgggcgagtccgtatctgtcatcaagcacacagaccctgttcctgacccccgagctgtc
aaccaggataagaagaacatgcttttctcgggtaccaacatcgcagctggcaaggcctta
ggcatcgtggccactactggtgtgagcaccgagattgggaagatccgtgaccagatggct
gccacggaacaggacaaaacccctctgcagcagaagctggatgagtttggggagcagctc
tccaaggtcatctccctcatctgtgtggccgtctggctcatcaacatcggccatttcaac
gatcccgtccacggcggctcctggttgcggggtgccatctactactttaagattgccgtg
gccctggctgtggccgcaatcccagaaggccttcctgcggtcatcaccacctgcctggcc
ttgggcacccggcggatggcaaagaaaaatgcaatcgtgaggagtctgccctccgtggag
actctgggctgcacctccgtcatctgttccgacaagacgggcaccctcaccaccaaccag
atgtctgtctgcaagatgtttattgtcgacaaggtggacggaaacatctgtgtcctgaac
gagttctccatcactggttccacttacgctccagaaggagaggtcttgaagaatgataag
ccagtccgctcagggcagtatgatgggctggtggagttggccaccatttgtgccctctgc
aatgactcctccttggacttcaacgaggccaaaggtgtttacgagaaggtgggtgaggca
acagagacggcgctcaccaccctggtggagaagatgaatgtgttcagcacagacgtgagg
agcctctcaaaagtggagcgggccaacgcctgcaactcagtgatccgccagctaatgaag
aaggaatttaccctggagttctcccgagaccggaagtccatgtctgtctattgctccccg
gccaaatcccgggctgccgtgggcaacaagatgttcgtcaagggtgcccctgagggggtc
atcgaccgctgtaactacgtgcgagttggcaccacccgcgtgccgattacagggccggtg
aaggacaagatcctgtccgtgatcaaggagtggggcaccggccgggataccctgcgctgc
ctggccctggccacccgggacacccccccgaagcgagaggagatgatcctggatgactct
gccaggttcatggagtacgagacggacctgacatttgtcggcgtggtgggcatgctggac
ccaccccgcaaggaggtcacgggctctattcagctgtgccgggatgccggaatccgagtc
atcatgatcaccggggacaacaagggcacagccattgccatctgccggcgaatcggcatc
tttggggagaacgaggaggtggccgaccgagcctacaccggccgggagtttgacgacctg
cccctggcggagcagcgggaggcctgccgtcgcgcctgctgcttcgcccgtgtggagccc
tcccataagtcgaagatcgtggagtatctgcagtcctacgatgagatcacggccatgacg
ggtgatggtgtcaacgatgcccctgccctgaagaaggccgagatcggcatcgccatggga
tccggcaccgccgtggccaagaccgcttccgagatggtgctggccgacgacaacttctcc
accatcgtggctgcggtggaggagggccgtgccatctacaacaacatgaagcagttcatc
cgctacctcatctcctccaacgtgggcgaggtggtctgcatcttcctgaccgccgcctta
ggactgcccgaggccctgatccctgtgcagctgctgtgggtgaacttggtgactgacggg
ctcccggccacagccctgggcttcaacccaccagacctggacatcatggaccggcctccc
cggagccccaaggagcccctcatcagtggctggctcttcttccgctacatggcaatcggg
ggctacgtgggtgcggccactgtgggagcggctgcctggtggttcctgtatgcagatgac
gggcctcacgtcacttacagccagctgactcacttcatgcagtgcaacgaggaaaacccc
gcctttgagggcctggactgcgaggtctttgaggccccccagcccatgaccatggccttg
tccgtgctggttaccattgaaatgtgcaacgctctcaacagcctgtctgagaaccagtcc
cttctgcggatgccgccctgggtgaacatctggctgctgggctccatctgcctgtccatg
tccctgcacttcctcatcctctatgtcgaccctctgccgatgatcttcaagctccgggcc
ctggactgcacccagtggctcatggtcctcaagatctcatttccagtcatcctgctcgat
gagctcctcaagttcattgctcggaactacctagaggatccagaagatgaaagaaggaag
taa
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