KEGG   Leopardus geoffroyi (Geoffroy's cat): 123590772
Entry
123590772         CDS       T10761                                 
Symbol
IGF1
Name
(RefSeq) insulin-like growth factor I isoform X1
  KO
K05459  insulin-like growth factor 1
Organism
lgf  Leopardus geoffroyi (Geoffroy's cat)
Pathway
lgf01521  EGFR tyrosine kinase inhibitor resistance
lgf01522  Endocrine resistance
lgf04010  MAPK signaling pathway
lgf04014  Ras signaling pathway
lgf04015  Rap1 signaling pathway
lgf04066  HIF-1 signaling pathway
lgf04068  FoxO signaling pathway
lgf04081  Hormone signaling
lgf04114  Oocyte meiosis
lgf04115  p53 signaling pathway
lgf04150  mTOR signaling pathway
lgf04151  PI3K-Akt signaling pathway
lgf04152  AMPK signaling pathway
lgf04211  Longevity regulating pathway
lgf04213  Longevity regulating pathway - multiple species
lgf04510  Focal adhesion
lgf04550  Signaling pathways regulating pluripotency of stem cells
lgf04730  Long-term depression
lgf04750  Inflammatory mediator regulation of TRP channels
lgf04913  Ovarian steroidogenesis
lgf04914  Progesterone-mediated oocyte maturation
lgf04935  Growth hormone synthesis, secretion and action
lgf04960  Aldosterone-regulated sodium reabsorption
lgf05200  Pathways in cancer
lgf05202  Transcriptional misregulation in cancer
lgf05205  Proteoglycans in cancer
lgf05214  Glioma
lgf05215  Prostate cancer
lgf05218  Melanoma
lgf05224  Breast cancer
lgf05410  Hypertrophic cardiomyopathy
lgf05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:lgf00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    123590772 (IGF1)
   04014 Ras signaling pathway
    123590772 (IGF1)
   04015 Rap1 signaling pathway
    123590772 (IGF1)
   04066 HIF-1 signaling pathway
    123590772 (IGF1)
   04068 FoxO signaling pathway
    123590772 (IGF1)
   04151 PI3K-Akt signaling pathway
    123590772 (IGF1)
   04152 AMPK signaling pathway
    123590772 (IGF1)
   04150 mTOR signaling pathway
    123590772 (IGF1)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    123590772 (IGF1)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    123590772 (IGF1)
   04115 p53 signaling pathway
    123590772 (IGF1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    123590772 (IGF1)
   04550 Signaling pathways regulating pluripotency of stem cells
    123590772 (IGF1)
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    123590772 (IGF1)
   04914 Progesterone-mediated oocyte maturation
    123590772 (IGF1)
   04935 Growth hormone synthesis, secretion and action
    123590772 (IGF1)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    123590772 (IGF1)
  09156 Nervous system
   04730 Long-term depression
    123590772 (IGF1)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    123590772 (IGF1)
  09149 Aging
   04211 Longevity regulating pathway
    123590772 (IGF1)
   04213 Longevity regulating pathway - multiple species
    123590772 (IGF1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    123590772 (IGF1)
   05202 Transcriptional misregulation in cancer
    123590772 (IGF1)
   05205 Proteoglycans in cancer
    123590772 (IGF1)
  09162 Cancer: specific types
   05214 Glioma
    123590772 (IGF1)
   05218 Melanoma
    123590772 (IGF1)
   05215 Prostate cancer
    123590772 (IGF1)
   05224 Breast cancer
    123590772 (IGF1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    123590772 (IGF1)
   05414 Dilated cardiomyopathy
    123590772 (IGF1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    123590772 (IGF1)
   01522 Endocrine resistance
    123590772 (IGF1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:lgf04052]
    123590772 (IGF1)
Cytokines and neuropeptides [BR:lgf04052]
 Cytokines
  Growth factors (RTK binding)
   123590772 (IGF1)
SSDB
Motif
Pfam: Insulin DUF2865
Other DBs
NCBI-GeneID: 123590772
NCBI-ProteinID: XP_045320203
LinkDB
Position
B4:complement(123297623..123375578)
AA seq 171 aa
MVTPTVKMHIMSPSHLFYLGLCLLTFTSSATAGPETLCGAELVDALQFVCGDRGFYFNKP
TGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSARSVRAQRHTDMPKAQKYH
PPSTTKKTKSQRRRKGGPKKHPGGEQKVGTEASQQMKGKKKEQRRETGARN
NT seq 516 nt   +upstreamnt  +downstreamnt
atggttacacctacagtaaagatgcacatcatgtccccctctcatctcttctatctgggc
ctgtgcttgctcaccttcaccagctccgccacagctggaccagagacgctctgtggggct
gagttggtggacgctcttcagttcgtgtgtggagacaggggtttttatttcaacaagccc
acggggtatggttccagcagtcggagggcacctcagacaggcatcgtggatgagtgctgc
ttccggagctgtgatctgaggcggctagagatgtactgtgcacccctcaagcctgccaag
tctgcccgctcagtccgtgctcagcgccacactgacatgcccaaggctcagaagtatcat
cccccatctaccaccaagaaaacgaagtctcagaggagaaggaaaggtgggccaaagaaa
cacccaggaggggagcagaaggtggggacggaagcaagtcagcagatgaaaggaaagaag
aaagagcagagaagggagactggagctagaaactga

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