Leopardus geoffroyi (Geoffroy's cat): 123593189
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Entry
123593189 CDS
T10761
Symbol
PDE5A
Name
(RefSeq) cGMP-specific 3',5'-cyclic phosphodiesterase isoform X1
KO
K13762
cGMP-specific 3',5'-cyclic phosphodiesterase [EC:
3.1.4.35
]
Organism
lgf Leopardus geoffroyi (Geoffroy's cat)
Pathway
lgf00230
Purine metabolism
lgf01100
Metabolic pathways
lgf04022
cGMP-PKG signaling pathway
Brite
KEGG Orthology (KO) [BR:
lgf00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
123593189 (PDE5A)
09130 Environmental Information Processing
09132 Signal transduction
04022 cGMP-PKG signaling pathway
123593189 (PDE5A)
Enzymes [BR:
lgf01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.35 3',5'-cyclic-GMP phosphodiesterase
123593189 (PDE5A)
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Motif
Pfam:
PDEase_I
GAF
GAF_2
HD-CE
DUF6970
Motif
Other DBs
NCBI-GeneID:
123593189
NCBI-ProteinID:
XP_045324716
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Position
B1:104382938..104523958
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AA seq
865 aa
AA seq
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MERASPGPGGSQLQRDQDSVEAWLDDHWDFTFSYFVRKATREMVNAWFAERVHTIPVCKE
GIRSHTESCSCPSQQSPRADSSAPGTPTRKISASEFDRPLRPIVVKDSEGTVSFLSDSEK
KEQMPLTPPRFDNDEGDQCSRLLELVKDISSHLDVTALCHKIFLHIHGLISADRYSLFLV
CEDSSNDKFLISRLFDVAEGSTLEEASNNCIRLEWNKGIVGHVAAFGEPLNIKDAYEDPR
FNAEVDQITGYRTQSILCMPIKNHREEVVGVAQAINKRSGNGGTFTEKDEKDFAAYLAFC
GIVLHNAQLYETSLLENKRNQVLLDLASLIFEEQQSLEVILKKIAATIISFMQVQKCTIF
IVDEDCSDSFSSVFHMECEELEKSSDTLTRERDANRINYMYAQYVKNTMEPLNIPDVSKD
KRFPWTNENTGSVSQQFIRSLLCTPIKNGKKNKVIGVCQLVNKMEENTGKVKPFNRNDEQ
FLEAFVIFCGLGIQNTQMYEAVERAMAKQMVTLEVLSYHASAAEEETRELQSLAAAVVPS
AQTLKITDFSFSDFELSDLETALCTIRMFTDLNLVQNFQMKHEVLCRWILSVKKNYRKNV
AYHNWRHAFNTAQCMFAALKAGKIQNKLTDLETLALLIAALSHDLDHRGVNNSYIQRSEH
PLAQLYCHSIMEHHHFDQCLMILNSPGNQILSGLSIEEYKTTLKIIKQAILATDLALYIK
RRGEFFELIRKNQFNLEDPHQKELFLAMLMTACDLSAITKPWPIQQRIAELVATEFFDQG
DRERKELNIEPADLMNREKKNKIPSMQVGFIDAICLQLYEALTHVSEDCFPLLDGCRKNR
QKWQALAEQQEKMLINGESSQAKRN
NT seq
2598 nt
NT seq
+upstream
nt +downstream
nt
atggagcgggccagcccgggccccggggggtcgcagttgcagcgggaccaggattcggtg
gaagcgtggctggatgatcactgggactttaccttctcttactttgttagaaaagccacc
agagaaatggtcaatgcctggtttgctgagagagtccacaccatccctgtgtgcaaagaa
ggtatcagaagccacacagaatcttgctcttgcccctcgcagcagagtccccgtgcagat
agcagtgcgcctggaacaccaaccaggaaaatctctgcctccgaatttgaccggcctctt
agacccattgttgtcaaggattctgagggaaccgtgagcttcctctctgactcagaaaag
aaggaacagatgcctctaacccccccaaggtttgataatgatgaaggggaccagtgctca
agactcttggaattagtgaaagatatctctagtcatttggatgtcacagccttatgtcac
aaaattttcttgcatattcatggacttatctctgccgatcgctattccctgttccttgtc
tgtgaggacagctccaacgacaagtttcttatcagccgcctgtttgatgttgcagaaggt
tcaacactggaagaagcttcaaataactgtatccgcttagaatggaacaaaggcattgtg
ggacacgtggcagcatttggtgagcccttaaacatcaaagatgcttacgaggatcctcgg
ttcaatgcagaagttgaccaaattacaggctacaggacacaaagtattctttgtatgccg
attaagaatcatagggaagaggttgttggtgtagcccaggccatcaacaagagatcggga
aatggtgggacattcactgaaaaagatgaaaaggactttgctgcctatttggcattttgt
ggtattgttcttcataatgctcaactctatgagacttcactgctggagaacaagagaaat
caggtgctgcttgaccttgctagcttaatttttgaagaacagcaatcattagaagtaatt
ctaaagaaaatagctgccactattatctctttcatgcaggtgcagaaatgcaccattttc
atagtggatgaagattgctccgattctttttctagtgtgtttcacatggagtgtgaagaa
ttagaaaaatcatcagatactttaacaagggagcgtgatgcaaacagaatcaattacatg
tatgctcagtatgtaaaaaatactatggaaccacttaatatcccagatgtcagtaaagac
aaaagatttccctggacaaatgaaaacacaggaagcgtaagtcaacagttcattagaagt
ttgctttgtacgcctataaaaaatggaaagaagaataaagtgataggggtttgccaactt
gtaaataagatggaggagaatactggcaaggttaagcctttcaaccgaaatgacgaacag
tttctggaggcttttgtcatcttttgtggcttggggatccagaacacacagatgtatgaa
gcagtggagagagccatggccaagcaaatggtcacactggaggttctgtcgtatcacgct
tcagcagcagaggaagaaacaagagagctccaatccttagcggctgctgttgtaccatct
gctcagacacttaaaattactgacttcagtttcagtgactttgagctgtctgacctagaa
acggcactgtgtacaattcggatgttcactgacctcaaccttgtgcagaacttccagatg
aaacatgaggttctttgcaggtggattttaagtgttaagaagaattaccggaagaatgtg
gcctatcataattggagacacgcctttaatacagctcagtgcatgtttgctgctctaaaa
gcaggcaagattcagaacaagctgaccgacctagagacactcgccctgctgattgctgct
ctcagccacgacttggaccaccgtggtgtgaataactcttacatacagcgaagtgaacac
ccacttgctcagctctactgccattcgatcatggagcatcatcattttgaccagtgcctg
atgattcttaatagtccaggcaatcagattctcagtggcctctccatcgaagaatataag
accacgctgaaaataatcaagcaagctattttagctacagacctagcactgtatattaag
agacgaggagaattttttgaacttataagaaaaaatcaattcaacttggaagatcctcat
caaaaagagttgtttttagcgatgctgatgacagcttgtgatctctctgcaattacaaaa
ccctggcctattcaacaacggatagcagaacttgtagcaactgaattttttgaccaagga
gacagagagagaaaagaactcaacatagagcctgctgatctgatgaacagggagaagaaa
aacaaaatcccaagtatgcaagttggattcatagatgccatctgcttgcaactatatgag
gccttgacccacgtttctgaggactgtttccctttgctggatggctgcaggaagaacagg
caaaaatggcaggctcttgcagaacagcaggagaaaatgctgattaatggggaaagcagc
caggccaagcggaactga
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