Leopardus geoffroyi (Geoffroy's cat): 123593532
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Entry
123593532 CDS
T10761
Symbol
SETX
Name
(RefSeq) probable helicase senataxin isoform X1
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
lgf Leopardus geoffroyi (Geoffroy's cat)
Pathway
lgf05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
lgf00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
123593532 (SETX)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
lgf03021
]
123593532 (SETX)
Enzymes [BR:
lgf01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
123593532 (SETX)
5.6.2.5 RNA 5'-3' helicase
123593532 (SETX)
Transcription machinery [BR:
lgf03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
123593532 (SETX)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AAA_11
AAA_12
AAA_19
UvrD-helicase
AAA_30
AAA_22
nSTAND3
ResIII
SLFN-g3_helicase
NAT10_TcmA_helicase
AAA_16
UvrD_C_2
Motif
Other DBs
NCBI-GeneID:
123593532
NCBI-ProteinID:
XP_045325486
LinkDB
All DBs
Position
D4:complement(90174575..90240569)
Genome browser
AA seq
2669 aa
AA seq
DB search
MSTCCWCTPGGISTADFLKRYASRTHAGEFQTANEDLCYCLECVAEYHKARDDLPFLHEV
LWELETLRLINHFEKSMKAEIGDDDELYIVDNNGEAQLFDFTGQDFENKLRVPLLEILKY
PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK
VDRDDYYDLQEVLTCLFKVIELGLLEDPDIYTCSVLEKGKLILLPSHMYDTTNYKSYWLG
ICMLLTILEEQAMDSLLLGSDKQNDFLQSILHTMERQADDDSVDPFWPALHCFMVILDRL
GSKVWGQRIDPIEAFQTIINNMSYNREIQNIRNSSVRTKSEPESYLGDTVTCSQIVYNYN
PEKTKKDSGWRSAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIPFVQSLMD
LKDLGVAYIVEVIHHLHSEVKDVLNQTDAVCDKVTEFFLLILVSVIELHRNKKCLHLLWV
SSQQWVEAVVKCAKLPTTAFARSSEKSSGNCSKGAAVISSLSLHSMPSNSVQLACVQLIR
SLLKEGYQLGQQTLCKRFWDKLNLFLRGNLSLGWQLTTQETHELQTCLKQIIRNIKIKVP
QCSTFVDLTPICKTPPASYNKEESEQTGKKSKKGLHCLENSSPTFSKGPLKAEAFQMPEN
RLVKASNASGEDSEHNYIKDLKLEGRLSAESCIKQGSKRLFPERAQDAVKTSKGKQKSVK
ENPTDSRNGLERGCDRGVIIAACSLTDSGTDSLEKASTSTEDFSFKDDVLGKTSKGKTKG
QKAEICAKLSHVIKKQHRKGTLIDDVNLEEKLTVSTIDSFFSRKDSGGQKGDGFINHLSL
DPDDVPDDKNGERKSQNSLLLKKKQFKSKELDIFSSHENSCQIQECQADGKDLVSFTEMT
DTCVKKTSPFKDPVTLLESRDKEVGKSTTSQVSSHLREQVPSLSPQSNTLTDSQIDRDLH
NLSLIAQASVIKFPSESTQTSSSQLQRKVKDKRCFAANPNNAGEACQGQVIIISDSDDDD
GDEGILGFEKHIKRDKIGIKKEYPEEHTSVASTNVEQELIKEEEAKSLLEFEESDSQFFE
FESPHEVFSVWQDQEPDNKNSVEEDENNSRLTHINDVTNDWGYDTDYVSEEVIKKVAEGI
EKHTEPQSGSSVGEFCETEVKKRKRKRYEKPVAEDPLRPSPSERNEDQSDNERGLTENDL
KSIELRSSSRSNLQRGTTDSLKKSSPKLRTYSKPVRRVPHSKTQKTHSDTKKGQNKSSNY
ISCRTTPAIVPPKILRQCPEPTSAVEKLGLKKAPRRAFDLSQRSLGYLVQLRDHGKTVGV
VDTRKKTKLISPQTLSVKNNKKLLTSQDLQSRRQAKPRSKQKRQGSLGSESRAPTRAGLR
SAQNPDTLVPESDSSDCRAKGGVEVGANSTGKPSIKHASSEPEPVKTKRVSQVAVDPCLS
NQCASVVLNGRKATHEAIVSTSADPLGGGDLTEHRLELPALKEGEPRSNSDSEDEDIFLT
QHDPADMDLCSQMESGNEKLIEIVHGKETALMEEESWSSTKCKYKDCVEAAQNQGEYCSK
HCEAKAVGEDVFRKPGLPPSASRRPSTAKVFSSSSTSRIANLSKSLESTSAPPPALKQKS
NGVPSVLKVPQPASVLSPKPAGEVKSLSDVLRPQTLNNSNRQGYKLTFGESRSFPASSAV
NVLLSSQSISDTFVKEVLKWKYEMFVNFDQCGPPTSLCQSISRPVPVRFQDCGDYFNVFF
PLMILNTFETVAQEWISSPNKEKFYQLHVRKFPADYKKYWEFVVHLEECELTKQLHPKEN
DLVFLVLEKQNGEKKNTERNRMPDLHEYHCGYVHKFRRTSVMRNGKSECSLSIQTQDNLP
LSLNELVKCTVISSLVTTQRKLKAMSLLSGRNQLARAILNPNPMDFCTKDLLTTTSERII
AYLKDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIVGLLYRLLTENQRKG
RSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCGDINLVRLGP
EKSINNEVLRFSLDSQVNHRMKKDLPSHVQEMHRRKEFLDHQLDELSRQRALCRGGKETQ
RQELDEKIAKVSKERQELASKIKEVQGRPQKTQSIIILESHVICCTLSTSGGLLLESAFR
GQGGVPFSCVIVDEAGQSCEVETLTPLIHRCNKLILVGDPKQLPPTVISMKAQEYGYDQS
MMARFCKLLEDSVEHNVISRLPILQLTVQYRMHPDICLFPSNYVYNRSLKTNRLTETNRC
SSDWPFQPYLVFDVGDGSERRDNDSYINVQEIKLVMEIIKLIKDKRRDVTFRNIGIITHY
KAQKTMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANAMQGSIGFLASLQRL
NVTITRAKYSLFILGHLRTLMENQHWNHLIQDAQKRGAIVKTCDKNYRHDAAKILKLKPV
LQRSLTHPPTVAPEVARPQGGLPSSKPDGEFAKTSFPSSLYHVPSGCKESTGAVTTKDPE
RPPIQDRLRDPRLLRRLGIDPEAKGTCPRDPQPLSPQHPGATPPSGEPGFPLSHQDLGGA
QLSTARGTTLSNQNPPVQWEPPAAGTDVSASKRACDWEGGLSRRRETRAFSEGDRETQSP
QRRHPKRRSGWDNRRPEEEDSGSKRRKFL
NT seq
8010 nt
NT seq
+upstream
nt +downstream
nt
atgagcacatgttgttggtgtacgcccggtggtatttccaccgccgacttcctcaagcgc
tatgcgtccaggacccacgccggggaatttcagacagccaacgaagacctgtgctactgc
ctggagtgtgtggccgagtaccacaaagcacgcgacgacctgcccttcctgcatgaggtt
ttgtgggaattagaaaccttacgtctcataaatcattttgaaaaatccatgaaggcagaa
attggagacgatgatgaattgtacatagtagacaacaacggagaggcacagctttttgac
ttcactggccaagactttgaaaataagcttcgggttcctcttcttgaaatcctgaagtat
ccgtatctgcttttacacgagcgtgttaacgaattatgtgttgaagcactttgtcggatg
gaacaagctaactgctcctttcaggtttttgacaaacatccaggcatttatttgtttctg
gtccatcccaatgaaatggttcggcgttgggctatcctgactgcaaggaacttgggaaaa
gtggacagagatgattattatgatctgcaggaggttttgacttgtctttttaaagtcatt
gagttggggcttctggaagatccagacatctatacttgttctgtcctcgagaagggtaaa
ctgattcttctgccttcgcacatgtacgataccaccaactacaagagctattggctaggt
atttgcatgttgctgaccattcttgaggagcaggctatggactccctgttgctgggctca
gacaaacagaatgatttcctgcaatcaatacttcacaccatggagaggcaagcagatgat
gatagcgtggatcctttctggccagcattgcactgtttcatggtgattctggatcgcctc
ggatcaaaggtctggggtcaacgcatcgatcctattgaggcgtttcagaccattatcaac
aacatgagctacaatagagagatccaaaatatacggaacagctctgtaaggaccaagtcg
gaaccggagtcgtatttgggtgatacagtgacttgtagccagatcgtgtacaattataac
cctgaaaagaccaaaaaggattccgggtggagatcagccatttgcccagattactgtcct
aacatgtacgaagagatggaaacgttagccagtgtgcttcagtcagatattggtcaagac
atgcgtgttcacaatagcacgtttctgtggttcatcccctttgttcagtccctcatggat
cttaaggatttgggtgtggcttacatagtagaggtgattcaccatctgcactctgaagtc
aaagatgtcctcaaccaaacagatgctgtgtgtgacaaagttactgagtttttccttctg
attttggtgtccgtgattgaactgcacagaaataaaaaatgtttgcacttgctgtgggtt
agttcccagcagtgggtggaggctgttgtaaaatgcgccaagcttcccaccaccgcgttt
gcacggagttctgagaagtcatctggaaattgctccaaaggagcagcagtgatatcgtct
ctgtcactgcattcgatgccgtctaattctgtccagctggcttgtgtgcagctgatcaga
agtctccttaaagaggggtatcagcttgggcagcagactctgtgcaagcgattctgggac
aagctcaacttatttctgcgtgggaatttatctctaggttggcagttgactactcaggaa
acccatgagttacaaacttgtttaaagcaaattattagaaacataaaaatcaaagtacct
cagtgtagcacttttgtggatctgactcccatatgtaaaacccctcctgcgtcttacaat
aaagaagaaagtgaacagacagggaagaaatctaaaaaaggcctgcactgtctggaaaac
tccagcccaacattttcgaaaggaccgttgaaagctgaggcatttcaaatgccagagaat
agattggtcaaagcaagtaacgctagcggagaggatagtgagcacaattacataaaagat
ttaaaactagaaggccgtctctcagcagagtcatgcataaagcagggtagcaaaaggctt
ttcccggaaagagctcaagatgcagttaaaacaagtaaagggaagcagaagtctgtgaag
gagaatcctacggattccagaaatggtctggaaaggggatgtgacagaggggtgataata
gccgcatgttcattgactgattctggcaccgactccctggagaaggcgtccacatcaact
gaggatttctctttcaaggatgatgttcttggcaaaacctcaaaaggaaaaactaaggga
cagaaagctgaaatctgtgctaagttatcacatgtaataaagaagcaacacaggaaaggt
actttgatcgatgatgtcaacttagaggaaaaactgactgtgtctaccattgacagtttc
ttttcaaggaaagattcaggaggtcagaaaggggatggcttcataaaccatctctcttta
gaccctgatgacgttcccgatgataaaaacggggagcgaaaatctcaaaacagtttattg
ctgaagaagaaacaattcaagagcaaagagttagatattttctcttcccatgaaaatagc
tgtcaaatacaggaatgccaggcagatggtaaagatttggtctcgtttacggaaatgacc
gatacttgtgtgaagaaaacctctcccttcaaagaccccgtgactcttcttgaatcgaga
gataaggaagttggcaagagtaccaccagtcaggtgtcttctcacttgagggaacaggtt
cctagcctcagtccacagtccaacaccttgacagattcccagatagaccgagacctccac
aacttatctttgatagcccaagccagtgttattaagtttccatcagagtcaactcaaaca
agctcatcccagctacaaagaaaagtaaaagataaaagatgtttcgcagctaacccgaat
aatgctggagaagcctgccagggccaggtgattattatttcagattctgatgatgatgat
ggtgatgaagggattctgggttttgagaaacacattaaacgagataaaataggcatcaag
aaagaatatccagaggagcatacttcagtagctagtacaaatgtggaacaggagctaata
aaggaagaagaggcaaagtccctattggagtttgaggaatcggattctcagttttttgag
tttgaaagtccacatgaggtgttttcagtttggcaagatcaggaaccagacaacaagaat
tcagttgaagaggatgaaaacaattcacgtctgactcacataaacgatgtcacgaatgat
tggggttacgatacagattatgtatctgaagaggttattaagaaagtagcagagggcatt
gaaaaacacacagaaccacagagtggtagttctgtcggggaattttgtgaaactgaagtg
aaaaaacgtaagagaaaacgatatgaaaaacctgtagctgaagatcctctgaggccttca
ccttctgagagaaatgaggaccagtctgataatgagagaggtctgactgaaaatgatctt
aaaagtatagagctgaggtcaagttccaggtcgaatcttcaaagaggcactacagattca
ctaaagaagtcttctccaaagcttcgtacttactccaaacccgttaggagagtcccgcat
tctaaaactcagaaaacacattcagataccaaaaaagggcagaataaaagttcgaattac
ataagttgtaggacgactcctgctatagtcccaccaaagatacttcgccagtgccctgaa
ccaacttcagctgttgaaaaacttggtctgaaaaaggctcctcgtagggcattcgattta
tctcagcgatctctagggtatttagttcagttacgggaccatggcaagaccgtgggagtg
gttgataccagaaaaaagaccaaattaatttctcctcagactctctctgtcaaaaataat
aagaaactgttgacaagtcaagatcttcagtcgcgaaggcaggcgaaacccagatcaaag
cagaagaggcaagggtccctgggttctgaaagcagagctcctacaagagcagggctgcgt
tcagcacagaatcctgacactctcgtcccagaatccgatagctcagattgtcgtgctaaa
ggaggcgtcgaggtgggtgctaacagtactggaaagccatcaataaaacacgcgtcttct
gaaccagaacccgtgaaaacgaaacgtgtttctcaggtggctgttgatccttgcctttcg
aaccagtgcgcttctgttgtgttaaatggaagaaaagcaacacatgaagccattgtctct
acgtcagctgaccctttaggcggaggcgacctaacagaacatcgtttagagttgcccgct
ctgaaagagggagagcccagatccaacagtgactcggaagatgaggatatatttctaacc
cagcacgatcccgcagatatggatttatgttcacaaatggaaagtggtaacgagaaactc
attgaaatagttcatggaaaagaaacagctctgatggaagaagaatcttggagcagcaca
aaatgtaagtacaaggattgtgtcgaagccgcgcaaaaccagggtgaatactgctccaaa
cactgcgaagctaaagcagtgggtgaagatgtgtttcgtaagccgggcttgcccccctct
gcgtccaggagaccctccactgccaaggtctttagctcaagtagtacttcacgaattgct
aatctttcgaagtctttggaaagtacctccgcaccgccaccggctctcaaacagaagtca
aacggggtaccatctgttttgaaagtcccacagccagcctctgtgttgtctccaaagcca
gcgggtgaggtgaagagtttgtctgatgttctccgtcctcagactctgaataattccaac
aggcaaggttacaagcttacctttggtgaaagcagatcttttccagcttcctctgcggta
aacgttctcttgtcctcacagtctatctcggacacctttgttaaggaggtcttaaagtgg
aagtatgaaatgtttgtgaactttgatcagtgtgggccccccaccagcctttgtcagtcc
atctcaagacctgtgcctgtcagatttcaagattgtggagattatttcaatgtttttttc
cctttgatgatactgaatacttttgaaacggtggcacaggagtggatcagctctccaaac
aaagagaagttctatcagttgcatgtacggaagtttcctgctgattataaaaagtactgg
gagtttgtggttcatcttgaggaatgtgaactaactaaacagctgcatccaaaggaaaat
gatttggtgtttttggttcttgaaaaacaaaatggagagaagaagaacacagagagaaat
cgcatgccggatctccacgaatatcactgcggttatgttcataaatttcgccgcacttca
gtcatgcgtaatgggaaatctgagtgttccctttccatccagactcaagataatttgcca
ctcagtttaaatgaactcgtgaaatgcactgtaatcagttctctggtaactacacaaagg
aagttgaaagccatgtctttgttgagtggacggaaccaactagccagagctattctgaac
ccaaaccccatggacttctgtacgaaagatttactgactacgacgtctgagagaatcatc
gcctacttgaaagatttcaacgaagaccaaaagaaagcgatagaaactgcatacgccatg
gtcaaacactccccatcagttgccaagatctgtttgattcatggaccacctggaacagga
aaatcaaaaactatcgttggcctcctgtaccgcctgctgacagagaaccagaggaagggg
cgttcagatgaaaactccaatgccaaaatcaaacaaaaccgtgtccttgtgtgtgcacct
tccaacgcggctgttgacgaactcatgaaaaaaatcatcctcgaatttaaagagaagtgt
aaagacaagaagaatcctttgggaaactgtggagatataaatttagtacgtctgggtcca
gaaaagtctattaataatgaggtcctaagatttagtttggacagccaagttaaccacaga
atgaaaaaagacttaccttctcatgttcaggagatgcatagaagaaaggaatttctggat
catcagctagatgaactttcccgccagcgtgctttatgccgaggtggaaaggaaacacag
aggcaagaattagatgaaaaaattgcaaaagtttcaaaagagaggcaggaactagcttct
aaaattaaagaggttcaaggacgcccgcaaaaaacacagagcatcatcatcttagagtcc
cacgtcatctgctgcacactgagcacgagtggcggtttactgctcgagtctgcttttcgt
gggcaagggggtgtccccttcagttgtgtcatcgtcgatgaggctgggcagtcttgtgaa
gtggagactcttaccccgctcatccatcgatgtaacaagctgatcctcgtcggagaccca
aaacagctccctcccacggtcatttccatgaaagcacaggagtatggctatgaccagtca
atgatggctcgcttctgcaagctgctggaagacagcgtagagcacaatgtgatcagcagg
ctgcccatcttacagcttactgttcagtacaggatgcacccagacatatgtctcttcccc
tctaattacgtttataacagaagcttgaaaacaaatagactgactgaaaccaatcggtgt
tcatcagactggccatttcaaccttacctcgtgtttgatgttggagacggttcagaaaga
cgggataatgactcatatataaatgttcaagaaataaaactggtaatggaaataattaaa
cttattaaagacaaaagaagggatgttactttccggaacattggcataataacccattac
aaggctcagaagacgatgattcagaaggatttggacaaagagtttgatagaaaagggccg
gcagaagtagataccgtggacgcgttccagggccgccagaaagattgtgttatcgtcacg
tgtgtcagagcaaatgccatgcaaggctccattggatttctggcaagtttgcaaagattg
aatgtcaccattacacgagccaagtacagcctcttcatcctcggacatttaaggaccttg
atggaaaatcagcactggaatcacctgattcaggacgcgcagaagcggggtgccattgtc
aagacgtgcgacaaaaactacaggcacgacgcagccaagattctgaaactcaagcccgtc
ctgcagagaagtctgactcacccgcccaccgtggccccggaggtggccagaccccagggt
ggcttgcccagcagcaagccagacggtgaatttgccaagacgtctttcccttcctccctg
tatcacgtgccttcgggctgcaaggaatccactggtgccgttaccaccaaggatcctgaa
agacctcctattcaggaccggcttcgggacccacgactgctcaggaggctgggcatagac
cccgaagccaaagggacgtgcccgagggatccgcagcccctgagcccccagcatcctggg
gccacgcctccctcgggggagccaggcttccctctgagtcaccaggacctgggtggtgcc
cagctgtccaccgccagagggaccacgctgagcaaccagaaccctcccgtgcagtgggag
cctccagctgccggtacggatgtctccgcgagtaaaagagcatgtgactgggaaggaggg
ctcagccgcaggagagagaccagggctttcagcgaaggggaccgggagacgcagagccct
cagcgccggcacccgaagaggcgctccggctgggacaacaggagaccggaggaggaagac
agtggttccaagagaagaaagtttttatag
DBGET
integrated database retrieval system
