Leopardus geoffroyi (Geoffroy's cat): 123593688
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Entry
123593688 CDS
T10761
Symbol
JAK2
Name
(RefSeq) tyrosine-protein kinase JAK2 isoform X1
KO
K04447
Janus kinase 2 [EC:
2.7.10.2
]
Organism
lgf Leopardus geoffroyi (Geoffroy's cat)
Pathway
lgf01521
EGFR tyrosine kinase inhibitor resistance
lgf04062
Chemokine signaling pathway
lgf04081
Hormone signaling
lgf04148
Efferocytosis
lgf04151
PI3K-Akt signaling pathway
lgf04217
Necroptosis
lgf04550
Signaling pathways regulating pluripotency of stem cells
lgf04630
JAK-STAT signaling pathway
lgf04658
Th1 and Th2 cell differentiation
lgf04659
Th17 cell differentiation
lgf04725
Cholinergic synapse
lgf04917
Prolactin signaling pathway
lgf04920
Adipocytokine signaling pathway
lgf04933
AGE-RAGE signaling pathway in diabetic complications
lgf04935
Growth hormone synthesis, secretion and action
lgf05140
Leishmaniasis
lgf05145
Toxoplasmosis
lgf05152
Tuberculosis
lgf05161
Hepatitis B
lgf05164
Influenza A
lgf05167
Kaposi sarcoma-associated herpesvirus infection
lgf05168
Herpes simplex virus 1 infection
lgf05200
Pathways in cancer
lgf05207
Chemical carcinogenesis - receptor activation
lgf05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
lgf05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
lgf00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
123593688 (JAK2)
04151 PI3K-Akt signaling pathway
123593688 (JAK2)
09133 Signaling molecules and interaction
04081 Hormone signaling
123593688 (JAK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
123593688 (JAK2)
09143 Cell growth and death
04217 Necroptosis
123593688 (JAK2)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
123593688 (JAK2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
123593688 (JAK2)
04659 Th17 cell differentiation
123593688 (JAK2)
04062 Chemokine signaling pathway
123593688 (JAK2)
09152 Endocrine system
04920 Adipocytokine signaling pathway
123593688 (JAK2)
04917 Prolactin signaling pathway
123593688 (JAK2)
04935 Growth hormone synthesis, secretion and action
123593688 (JAK2)
09156 Nervous system
04725 Cholinergic synapse
123593688 (JAK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
123593688 (JAK2)
05207 Chemical carcinogenesis - receptor activation
123593688 (JAK2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
123593688 (JAK2)
09172 Infectious disease: viral
05161 Hepatitis B
123593688 (JAK2)
05164 Influenza A
123593688 (JAK2)
05168 Herpes simplex virus 1 infection
123593688 (JAK2)
05167 Kaposi sarcoma-associated herpesvirus infection
123593688 (JAK2)
09171 Infectious disease: bacterial
05152 Tuberculosis
123593688 (JAK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
123593688 (JAK2)
05140 Leishmaniasis
123593688 (JAK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
123593688 (JAK2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
123593688 (JAK2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
123593688 (JAK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
lgf01001
]
123593688 (JAK2)
Enzymes [BR:
lgf01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
123593688 (JAK2)
Protein kinases [BR:
lgf01001
]
Non-receptor tyrosine kinases
JAK family [OT]
123593688 (JAK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
SH2_1
Jak1_Phl
ABC1
FERM_C_FAK1
RIO1
Kinase-like
FERM_M
Motif
Other DBs
NCBI-GeneID:
123593688
NCBI-ProteinID:
XP_045325940
LinkDB
All DBs
Position
D4:complement(6571869..6690103)
Genome browser
AA seq
1131 aa
AA seq
DB search
MGMACLTMTEMEGVSVSPVHQNGDIPGNANSVKQIDPLLQVYLYHSLEKADGEYLKFPTG
EYVAEEICVAASKACGITPVYHSMFALMSETERTWYPPNHVFHVDESTRHNVLYRIRFYF
PYWYCNGSNRTYRHGVSRGAEAPLLDDFVMSYLFAQWRHDFLHGWIKIPVTHETQEECLG
MAVLDMMRLAKEKDQTPLDIYSSISYKTFLPKCVRAKIQDYHILTRKRIRYRFRRFIEQF
SHCKATARNLKLKYLINLETLQSAFYTEQFEVKEPGRGPSGEEIFATIVITGNGGIQWSR
GKHKESETLTEQDLQLYCDFPDIIDVTIKQGNQEGSNESRIVTIHKQDGKNLEIELSSLR
EALSFVSLIDGYYRLTADAHHYLCKEVAPPMVLENIQSNCHGPILMDFAISKLKKAGNQT
GLYVLRCSPKDFNKYFLTFAVERDNVIEYKHCLITKNENGEYNLSGTKKNFSNLKDLLNC
YQMETVRSDSIIFQFTKCCPPKLKDKSNLLVFRTNGVSDVPTSPTLQRHNNVNQMVFHKI
RNEDLIFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASM
MSQLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSISILWKLEVAKQLAWA
MHFLEEKALIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVP
PECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWTEL
ANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNRIGTLGFSGAFEDRDP
TQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEI
LKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTSQIC
KGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWY
APESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIEL
LKNNGRLPRPDGCPDEIYLIMTECWNNNVNQRPSFRDLALRVDQIRDNMAG
NT seq
3396 nt
NT seq
+upstream
nt +downstream
nt
atgggaatggcttgccttaccatgacggaaatggaaggagtatctgtatctcctgtacat
cagaatggtgatattcctggaaatgctaattctgtgaagcaaatagatccactcctacag
gtgtatctttatcattctcttgagaaggctgatggagaatatctgaagtttccaactggg
gagtatgttgcagaagaaatttgtgttgctgcttctaaagcttgtggaatcacgcccgtg
tatcatagtatgtttgctttaatgagtgaaaccgaaaggacctggtatccgcccaaccat
gtcttccatgtagatgaatcaaccaggcacaacgtactctacagaataagattttacttt
ccttactggtattgtaatggcagcaacagaacctatcggcatggagtgtctcgaggtgct
gaagctcctcttcttgatgactttgtcatgtcttacctttttgctcagtggcggcatgat
tttttacatggatggataaaaataccggtgactcatgaaacgcaggaagaatgtcttgga
atggcagtgttagatatgatgagactagccaaagagaaggatcaaaccccattggacatc
tatagctctatcagctacaagacattcttaccaaaatgtgttcgagcaaagatccaagac
tatcatattttgacaaggaagagaataaggtatagatttcgcagatttattgagcagttc
agccattgcaaagccactgccagaaacttgaaacttaagtatcttataaatctggaaaca
cttcagtctgccttctacacagagcaatttgaagtaaaagaacctggaagaggtccttca
ggtgaggagatttttgcaaccattgtaataactggaaacggtggaattcagtggtcaaga
gggaaacataaagaaagtgagacactgacagaacaggatttacagttatattgtgacttt
cctgatatcattgatgtgactattaaacaaggaaaccaagaaggctcaaatgaaagtaga
attgtaactatccataagcaagatggtaaaaatctggaaattgaactaagctcattaaga
gaagctttatcctttgtgtcattaattgatggctattacagattaaccgcggatgcacat
cattacctctgtaaagaagtagctcctccgatggtgcttgaaaatatacaaagcaactgt
catggcccgattttaatggattttgccatcagtaaactgaagaaagcaggtaatcagact
ggactctatgtacttcgatgcagtcctaaggactttaataaatattttctgacttttgct
gtcgagcgagataatgtcatcgaatataagcattgtttgattacaaaaaatgagaatgga
gaatacaacctcagtgggaccaagaagaacttcagtaatcttaaagatcttttgaattgc
taccagatggaaactgttcgctcagacagtataattttccagtttactaaatgctgcccc
ccaaagttgaaagataaatcaaatcttctagtctttagaaccaatggcgtttctgatgta
ccaacatcaccaacattacagaggcataataatgtgaaccaaatggtgtttcacaaaatc
agaaatgaagatttgatatttaatgaaagccttgggcaaggcacttttacaaaaattttt
aaaggtgtaagaagagaagtaggagactatggtcaactgcatgaaacagaagttctttta
aaagttctggataaagcacacagaaactattcagagtctttctttgaagcagcaagcatg
atgagccagctttctcacaagcacctggttttaaattatggagtatgtgtctgtggagag
gaaaatattctggttcaggagtttgtaaaatttggatcattagatacatacctgaaaaag
aataaaaattctataagtatattatggaaacttgaagtggctaaacagttggcatgggcc
atgcattttctagaagaaaaagcccttattcatgggaatgtgtgtgccaaaaatattctg
cttatcagagaagaagacagaaagacaggaaatcctcctttcatcaaacttagtgatcct
ggcattagtattacagttttgccaaaggacattcttcaggagagaataccatgggtacca
cctgaatgcattgaaaatcctaaaaatctaaacttggcaacagacaaatggagttttggt
accactttgtgggaaatctgcagtggaggagacaagcctctgagtgctttggattctcaa
agaaagctccagttttatgaagataggcaccagcttcctgcaccaaagtggacagaatta
gcaaatcttattaataattgtatggattatgaaccagattttagaccttctttcagagcc
atcatacgagatcttaatagtttgtttactccagattacgagctattaacagaaaatgac
atgttgccaaataggataggcacccttgggttttctggagcttttgaagaccgagacccg
acacagtttgaagagagacacttgaaatttctacagcagcttggcaagggcaattttggc
agtgtggagatgtgccggtatgaccctctacaagacaacactggggaggtggtggccgtg
aagaagctccagcacagtactgaggagcacctgagagactttgaaagagaaattgaaatc
cttaaatccctgcagcatgacaacattgtcaagtacaagggagtgtgctacagtgctggc
cggcgtaatttaagattaattatggaatatttaccatatggaagtttacgagattatctc
caaaaacataaagaacggatagatcataaaaaacttctgcagtatacatctcagatatgc
aagggcatggagtatcttggtacaaaaaggtatatccacagggatctggcaacaaggaat
atattggtggagaatgaaaacagggttaaaattggagattttggtttaaccaaagtcttg
ccacaagacaaagaatactacaaagtgaaagaacctggtgaaagtcccatattctggtat
gctccagaatcactgacagagagcaagttttctgtggcttcagatgtttggagctttgga
gtggttctgtatgaacttttcacatacatcgagaagagtaaaagtccaccagcggaattt
atgcgtatgattggcaatgacaaacaaggacagatgattgtgtttcatttgatagaactc
ctaaagaataatggaagattaccaagaccagatggatgcccagatgagatttatttgatt
atgactgaatgctggaacaataatgtaaatcagcgcccctcctttagagacctagctctt
cgagttgatcaaataagggacaacatggctggatga
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integrated database retrieval system
