Leopardus geoffroyi (Geoffroy's cat): 123593754
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Entry
123593754 CDS
T10761
Symbol
CACNA1B
Name
(RefSeq) voltage-dependent N-type calcium channel subunit alpha-1B isoform X1
KO
K04849
voltage-dependent calcium channel N type alpha-1B
Organism
lgf Leopardus geoffroyi (Geoffroy's cat)
Pathway
lgf04010
MAPK signaling pathway
lgf04020
Calcium signaling pathway
lgf04721
Synaptic vesicle cycle
lgf04723
Retrograde endocannabinoid signaling
lgf04725
Cholinergic synapse
lgf04726
Serotonergic synapse
lgf04727
GABAergic synapse
lgf04728
Dopaminergic synapse
lgf04930
Type II diabetes mellitus
lgf05016
Huntington disease
lgf05020
Prion disease
lgf05022
Pathways of neurodegeneration - multiple diseases
lgf05032
Morphine addiction
lgf05033
Nicotine addiction
lgf05207
Chemical carcinogenesis - receptor activation
Brite
KEGG Orthology (KO) [BR:
lgf00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
123593754 (CACNA1B)
04020 Calcium signaling pathway
123593754 (CACNA1B)
09150 Organismal Systems
09156 Nervous system
04727 GABAergic synapse
123593754 (CACNA1B)
04725 Cholinergic synapse
123593754 (CACNA1B)
04728 Dopaminergic synapse
123593754 (CACNA1B)
04726 Serotonergic synapse
123593754 (CACNA1B)
04723 Retrograde endocannabinoid signaling
123593754 (CACNA1B)
04721 Synaptic vesicle cycle
123593754 (CACNA1B)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
123593754 (CACNA1B)
09164 Neurodegenerative disease
05016 Huntington disease
123593754 (CACNA1B)
05020 Prion disease
123593754 (CACNA1B)
05022 Pathways of neurodegeneration - multiple diseases
123593754 (CACNA1B)
09165 Substance dependence
05032 Morphine addiction
123593754 (CACNA1B)
05033 Nicotine addiction
123593754 (CACNA1B)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
123593754 (CACNA1B)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
lgf04040
]
123593754 (CACNA1B)
Ion channels [BR:
lgf04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
123593754 (CACNA1B)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ion_trans
Ca_chan_IQ
GPHH
PKD_channel
Phage_TAC_15
Motif
Other DBs
NCBI-GeneID:
123593754
NCBI-ProteinID:
XP_045326164
LinkDB
All DBs
Position
D4:94241256..94434373
Genome browser
AA seq
2356 aa
AA seq
DB search
MVRFGDELGSRYGGAGGERARGGGAGGAGGPGPGGLQPGQRVLYKQSIAQRARTMALYNP
IPVKQNCFTVNRSLFVFSEDNVVRKYAKRITEWPPFEYMILATIIANCIVLALEQHLPDG
DKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVFHKGSYLRNGWNVMDFVVVLTGILAT
AGTDFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAILMFAIIG
LEFYMGKFHKACFPNSTDPEPVGDFPCGKEAPARLCEGDTECREYWPGPNFGITNFDNIL
FAILTVFQCITMEGWTDILYNTNDAAGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFAK
ERERVENRRAFLKLRRQQQIERELNGYLEWIFKAEEVMLAEEDKNAEEKSPLDAVLKRAA
TKKSRNDLIHAEEGEDRFADLCAVGSPFARASLKSGKTESSSYFRRKEKMFRFFIRRMVK
AQSFYWVVLCVVALNTLCVAMVHYNQPQRLTTALYFAEFVFLGLFLTEMSLKMYGLGPRS
YFRSSFNCFDFGVIVGSIFEVVWAAIKPGTSFGISVLRALRLLRIFKVTKYWSSLRNLVV
SLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFQDETPTTNFDTFPAAILTVFQIL
TGEDWNAVMYHGIESQGGVSKGMFSSFYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTK
DEEEMEEAANQKLALQKAKEVAEVSPMSAANISIAAAFVKHTRGAASHSSSVSSINSPRP
QNSAKARSVWEQRASQLRLQNLRASCEALYSEMDPEERLRYATTRHLRPDMKTHLDRPLV
VELGRDGPRGPPGGKARPEGAEAGEGTDPPRRHHRHRDKAPAAAPAAAAAAAEQDRADAP
KAEGGESGAREERARPHRSRSKEARSERGRGPGPEGGRRHHRRGSPEEAAEREPRRHRAH
RHAPDQGKESAAPGTKGERRARHRGGPRAGPREAGSGEEPARRHRARHKALPVHEDAEKE
GEVEDRDKEKELRNHQPKEPRCDLEASEMMGVGPVHALPSTCLQKVEEQPEDADNQRNVT
RMGSQPSDLSATVHIPVTLTGPPGETTVVPSGNVDLESQAEGKKEVEADDVMRSGPRPIV
PYSSMFCLSPTNLLRRFCHYIVTMRYFEMVILVVIALSSIALAAEDPVRTDSPRNNALKY
MDYIFTGVFTFEMVIKMIDLGLLLHPGAYFRDLWNILDFIVVSGALVAFAFSSFMGGSKG
KDINTIKSLRVLRVLRPLKTIKRLPKLKAVFDCVVNSLKNVLNILVVYMLFMFIFAVIAV
QLFKGKFFYCTDESKGLERDCRGQYLDYEKEEVEAQPRQWKKYDFHYDNVLWALLTLFTV
STGEGWPMVLKHSVDATYEEQGPSPGYRMELSIFYVVYFVVFPFFFVNIFVALIIITFQE
QGDKVMSECSLEKNERACIDFAISAKPLTRYMPQDKQSFQYKTWTFVVSPPFEYFIMAMI
ALNTVVLMMKFYNAPYEYELMLKCLNIVFTSMFSMECVLKIIAFGVLNYFRDAWNVFDFV
TVLGSITDILVTEIAETNNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPY
VCLLIAMLFFIYAIIGMQVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIM
LSCLSNQACDEHANANECGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSIL
GPHHLDEFIRVWAEYDPAACGRISYNDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMP
ISNEDMTVHFTSTLMALIRTALEIKLAPAGTKQHQCDAELRKEISSVWANLPQKTLDLLV
PPHKPDEMTVGKVYAALMIFDFYKQNKTTRDQIHQATGGLSQMGPVSLFHPLKATLEQTQ
PAVLRGARVFLRQKSSASLSNGGAVQTQESGIKESVSWGTQRTQEVPCEARTPLERGHST
EIPAMHPGKPAVDVQMQSVALRGPDGEPQPGLESQGRAASMPRLAAETQPAPDASPMKRS
ISTLAPQRPHVAHLCNAALDRAPASQAVPHHHHRCHRRRDRKQKSLEKGPSLSADADGAP
SSAAGPGPPPGEGPTGCRRERRQERGRSQERRQPSSSSSEKQRFYSCDRFGGREPLQPKP
SLSSHPTSPTAGQEPGPPRQGGGSVNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSVTY
KTANSSPVHFAGAQTSLPTFSPGRLSRGLSEHNALLQRDPLSQPLAAGSRIGSDPYLGQR
LDSEDTVRAQPEDTLTFEEAVATNSGRSSRTSYVSSLTSQSHPLRRVPNGYHCTLGLSSG
GRVRHSYHHPDQDHWC
NT seq
7071 nt
NT seq
+upstream
nt +downstream
nt
atggtccgcttcggggacgagctgggcagccgctatgggggcgccggtggggagcgggct
cggggcggcggggccggcggggcgggcggcccgggccccggggggctgcagccgggccag
cgggtcctctacaagcagtcgatcgcgcagcgcgcgcggactatggcgctctacaacccc
atcccggtcaagcagaactgcttcaccgtcaaccgctcgctcttcgtcttcagcgaggac
aacgtcgtccgcaaatacgccaagcgcatcaccgagtggcctccatttgaatacatgatc
ctggccaccatcatcgccaactgtattgtgctggcactggagcagcacctgcctgacggg
gacaagacacccatgtctgagcggctggatgacacggagccctacttcattggcatcttc
tgctttgaggcggggatcaagatcatagctctgggcttcgtcttccacaagggctcctac
ttgcggaacggctggaacgtcatggacttcgtggtggttctcacagggatcctggccaca
gcgggcactgacttcgacctgaggaccctgcgggccgtgcgtgtgctcaggcccctgaag
ctggtgtctgggattccgagtctgcaggtggtgctcaagtccataatgaaggccatggtc
ccgcttctgcagattgggttgcttctcttctttgccatcctcatgtttgccatcattggc
ctcgagttctacatgggaaaattccacaaggcctgtttccccaacagcacagatccagag
ccagtgggtgactttccctgtggcaaggaggccccagcccggctgtgtgagggcgacacc
gagtgccgggagtactggccgggacccaactttggcatcaccaactttgacaatatcctg
tttgccatcttgacagtgttccagtgcatcaccatggagggatggactgacatcctttat
aacacaaatgatgcagccggcaacacctggaactggctctacttcatccctctcatcatc
atcggctccttcttcatgctcaacctggtgttgggtgtgctctcaggagagtttgccaag
gagcgtgagagggtcgagaaccgccgggccttcctgaagctccgccggcagcagcagatt
gagcgggagctcaatgggtacctggaatggatcttcaaggctgaggaagtcatgctggct
gaggaggacaagaatgcggaggagaagtcccctctggatgcagtgttgaagagagcagcc
accaagaagagccggaatgacctgatccatgccgaggagggggaggaccggtttgcagac
ctctgtgccgttggatcccccttcgcccgcgccagcctcaagagtgggaagacagagagt
tcgtcatacttccgtaggaaggagaagatgttccggttcttcatccgccgcatggtgaag
gcacagagcttctactgggtggtgctgtgtgtggtggccctgaatacgctgtgcgtggcc
atggttcactacaaccagccgcagcggctcaccacggcgctgtactttgcagagtttgtt
ttcctgggtctcttcctcacagagatgtccctgaagatgtatggcctggggcccagaagc
tacttccggtcctcattcaactgcttcgactttggggtcattgtggggagcatctttgaa
gtggtctgggccgccatcaagccgggaacctccttcgggatcagcgtgctgcgggcactc
cggttgctgcggatcttcaaagtcacaaagtactggagctccctgcggaacctggtggtg
tctctgctcaactccatgaagtctatcatcagcctccttttcctgctgttcctgttcatc
gtggtctttgccctgctgggcatgcagctgttcgggggacagttcaactttcaagatgag
accccgacaaccaactttgacaccttccccgcggccatccttaccgtcttccagatccta
acaggagaggactggaatgcagtgatgtatcatgggatcgaatcgcaaggtggagtcagc
aaaggcatgttctcctctttttatttcattgtcctgacgctgtttggaaattacactctg
ctgaatgtcttcctggccatcgccgtggacaacctcgccaacgctcaggagctgaccaag
gatgaagaggagatggaagaagcagccaatcagaagcttgctctgcaaaaggccaaagaa
gtggctgaagtgagccccatgtctgccgcaaacatctctattgctgctgcttttgtaaag
cacacgcgaggtgctgcctctcacagctcatctgtctccagcataaactcacccaggccg
cagaactcggccaaagcacgctcggtctgggagcagagggccagccagctgcggctgcag
aacctgcgggccagctgcgaggcgctgtacagcgagatggaccccgaggagcggctgcgc
tacgccaccacgcgccacctgcggccggacatgaagacgcacctggaccggccgctcgtg
gtggagctgggccgcgacgggccgcggggccccccggggggcaaggcccggcccgagggc
gcagaggccggcgagggcacggacccaccccgcaggcaccaccggcaccgcgacaaggcc
ccggcagcggccccggcggcggcggcggcggcggcggagcaggacagggcagacgccccg
aaggccgagggcggggagtccggggcccgggaggagcgggcgcggccgcaccgcagccgc
agcaaggaggcccggagcgagcgcggccgcggcccgggccccgagggcggccggcgccac
caccggcgcggctccccggaggaggcggccgagcgggagccccggcgccaccgcgcccac
cggcacgcacccgaccagggcaaggagagcgccgcgcccgggaccaagggagagcggcga
gcgcgccaccgcggcggcccccgggccggcccccgggaggccggcagcggcgaggagccg
gcgcggcggcaccgggcccggcacaaggcgctgcccgtgcacgaggacgcggagaaggag
ggcgaggtcgaggacagggacaaggagaaggagctccggaaccatcagcccaaggagcca
cgctgtgacctggaggccagtgagatgatgggtgtgggccctgtacatgcactgcccagc
acctgcctacagaaggtggaggaacagccagaagatgcagacaatcagcggaatgtcaca
cggatgggcagtcaaccctcggacctgagtgccactgtgcatatcccggtgacgctgact
ggccctcctggggagaccacggttgttcccagtggtaatgtggacctggaaagccaagct
gaagggaagaaggaggtagaagccgatgacgtgatgaggagtggcccccgacctatcgtc
ccgtacagctccatgttctgcttaagtcccaccaacctgctccgccgcttctgccattac
atcgtgaccatgcggtactttgagatggtcattcttgtggtcatcgccctgagcagcatt
gccctggcagccgaggatcctgtgcggacagactcgcccaggaacaacgctctgaaatac
atggactacattttcacaggcgtctttacctttgagatggtgataaagatgattgatttg
ggactgctgctgcaccctggggcctacttccgggacctgtggaatattctggacttcatc
gtggtcagtggggccttggtggcatttgccttctcgagcttcatgggaggatccaaaggg
aaagacatcaacaccatcaagtccctgagagtcctgcgtgtcctgcggcccctcaagacc
ataaaacggctgcctaagcttaaggccgtgtttgactgtgtggtgaactccctgaagaac
gtccttaacatcctggttgtctatatgctcttcatgttcatatttgctgtcattgcggtg
cagctcttcaaagggaagtttttctactgcacggatgagtccaaggggctggagagggac
tgccggggtcagtatttggattatgagaaggaggaagtggaagctcaaccacggcagtgg
aagaaatacgattttcactatgacaatgtgctctgggctctgctgacactgttcacagtg
tccacgggagaagggtggcccatggtcctgaaacactctgtggatgccacctatgaggag
cagggcccaagccccgggtaccgcatggagctatccatcttctatgtggtctactttgtg
gtcttccccttcttcttcgtcaatatctttgtggccttgattatcatcaccttccaggag
cagggggacaaggtgatgtctgagtgcagcctggagaagaacgagagggcttgcattgac
tttgccatcagcgccaagcccctgacacggtacatgccccaggacaagcagtcgttccag
tacaagacgtggacgtttgtcgtgtctccgccctttgagtacttcatcatggccatgatt
gccctcaacacggtggtgctgatgatgaagttctacaatgcaccctatgaatacgagctg
atgttgaaatgcctgaacattgtgttcacatccatgttctccatggaatgcgtgctgaag
atcatcgcctttggggtgctgaactatttcagagatgcctggaatgtctttgactttgtc
actgtgttgggaagtattactgatattttagtaacagagattgcggaaacgaacaacttc
atcaacctcagcttcctacgcctcttccgtgctgcccggctcatcaagctgctccgccaa
ggctacaccatccgcatcctgctgtggaccttcgtccagtccttcaaggccctgccttac
gtgtgtctgctcatcgccatgcttttcttcatctatgccatcattggcatgcaggtattt
ggaaatattgccctggatgatgacaccagcatcaaccggcacaacaactttcgaacattt
ttacaagccttgatgctgttgttcaggagtgccactggggaggcctggcacgagatcatg
ctgtcttgtctcagcaaccaggcctgtgatgagcacgccaatgccaatgagtgtgggagc
gactttgcctacttttacttcgtctccttcatcttcctttgctcctttctgatgttgaac
ctctttgtggccgtgatcatggacaattttgagtaccttacacgggactcttccatctta
gggcctcaccatctggacgagttcatccgggtctgggctgagtacgacccggccgcgtgt
gggcgcatcagttacaatgacatgtttgagatgctgaaacacatgtccccgcccctgggg
ctggggaagaaatgccctgctcgagttgcatacaagcgcctggttcgcatgaacatgccc
atctccaatgaggacatgactgtccacttcacgtccacgctgatggccctcattcggacc
gcactggagatcaagctggctccagctggcacaaagcagcatcagtgtgatgcagagttg
aggaaggagatttcctccgtgtgggccaatctgccccagaagaccctggatttactggtg
ccacctcataaacctgacgagatgacagtggggaaagtctatgcagctctgatgatattt
gacttctacaaacagaacaagaccaccagagaccagattcaccaggccactggaggccta
tcccagatgggccctgtgtccctcttccaccctctgaaggccaccctggagcagacacag
ccggccgtgctccgaggagcccgggtgttccttcggcagaagagctctgcgtccctcagc
aacggtggggcagtacaaacccaagagagtggcatcaaggagtctgtctcctggggcact
cagaggacccaggaggtaccctgtgaggcaaggacacccctggagcgtggccactctaca
gagatcccggcgatgcatccaggaaaaccggctgttgatgtccagatgcagagcgtggcc
ctgagaggtcctgacggggagccccaacctgggctggagagtcagggacgagcggcctcc
atgccccgcctggctgcagagacccagccggcccctgacgccagccccatgaagcgctcc
atctccacgctggcgccccagcgcccccatgtggctcatctctgcaacgctgccctggac
cgcgccccagccagccaggctgtgccccaccaccaccaccgctgccaccgccgcagggac
aggaagcagaagtccctggagaaggggcccagcctgtccgcagacgcagatggcgcaccc
agcagtgctgcagggccggggccacccccgggagaggggcccacaggctgccggcgggag
cgtaggcaggagcgtggccggtcccaagagcggaggcagccctcttcctcctcctcggag
aagcagcgcttctactcctgtgaccgctttgggggccgtgagcccctgcagcccaagccc
tccctcagcagccaccccacatcaccgacagccgggcaggagccaggacccccgagacag
ggtggtggttcagtgaatgggagtcccttgttgtcaacatcaggtgctagcacccctggc
cgcggtgggcggaggcagctcccccagactccgctgaccccccgtcccagtgtcacctac
aagacggccaactcttcccctgtccacttcgctggggcgcagaccagcctccccaccttc
tcccctggccggcttagccgtggcctttctgaacacaacgccctgctccagagagacccc
ctcagccagcctctggctgctggctctcggatcggctccgacccttacctggggcagcgt
ctggacagtgaggacactgtccgcgcccagcctgaggacacgctcaccttcgaggaggct
gtggccaccaactcggggcgctcctcccggacttcctatgtgtcctctctgacctcccag
tcccaccccctccgtcgcgtgcccaatggctaccactgcactctgggactcagctcgggc
ggccgggttcggcacagctaccaccaccccgaccaagaccactggtgctag
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integrated database retrieval system
