Leopardus geoffroyi (Geoffroy's cat): 123595979
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Entry
123595979 CDS
T10761
Symbol
PDGFRA
Name
(RefSeq) platelet-derived growth factor receptor alpha
KO
K04363
platelet-derived growth factor receptor alpha [EC:
2.7.10.1
]
Organism
lgf Leopardus geoffroyi (Geoffroy's cat)
Pathway
lgf01521
EGFR tyrosine kinase inhibitor resistance
lgf04010
MAPK signaling pathway
lgf04014
Ras signaling pathway
lgf04015
Rap1 signaling pathway
lgf04020
Calcium signaling pathway
lgf04072
Phospholipase D signaling pathway
lgf04144
Endocytosis
lgf04151
PI3K-Akt signaling pathway
lgf04510
Focal adhesion
lgf04540
Gap junction
lgf04630
JAK-STAT signaling pathway
lgf04810
Regulation of actin cytoskeleton
lgf05163
Human cytomegalovirus infection
lgf05200
Pathways in cancer
lgf05206
MicroRNAs in cancer
lgf05214
Glioma
lgf05215
Prostate cancer
lgf05218
Melanoma
lgf05230
Central carbon metabolism in cancer
lgf05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
lgf00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
123595979 (PDGFRA)
04014 Ras signaling pathway
123595979 (PDGFRA)
04015 Rap1 signaling pathway
123595979 (PDGFRA)
04630 JAK-STAT signaling pathway
123595979 (PDGFRA)
04020 Calcium signaling pathway
123595979 (PDGFRA)
04072 Phospholipase D signaling pathway
123595979 (PDGFRA)
04151 PI3K-Akt signaling pathway
123595979 (PDGFRA)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
123595979 (PDGFRA)
09144 Cellular community - eukaryotes
04510 Focal adhesion
123595979 (PDGFRA)
04540 Gap junction
123595979 (PDGFRA)
09142 Cell motility
04810 Regulation of actin cytoskeleton
123595979 (PDGFRA)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
123595979 (PDGFRA)
05206 MicroRNAs in cancer
123595979 (PDGFRA)
05230 Central carbon metabolism in cancer
123595979 (PDGFRA)
05231 Choline metabolism in cancer
123595979 (PDGFRA)
09162 Cancer: specific types
05214 Glioma
123595979 (PDGFRA)
05218 Melanoma
123595979 (PDGFRA)
05215 Prostate cancer
123595979 (PDGFRA)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
123595979 (PDGFRA)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
123595979 (PDGFRA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
lgf01001
]
123595979 (PDGFRA)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
lgf04090
]
123595979 (PDGFRA)
Enzymes [BR:
lgf01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
123595979 (PDGFRA)
Protein kinases [BR:
lgf01001
]
Receptor tyrosine kinases (RTK)
PDGFR family [OT]
123595979 (PDGFRA)
CD molecules [BR:
lgf04090
]
Proteins
123595979 (PDGFRA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Ig_PDGFR_d4
Pkinase
Ig_3
I-set
ig
Ig_2
VEGFR1-3_N_Ig-like
V-set
VEGFR-1-like_Ig-like
Herpes_gE
Motif
Other DBs
NCBI-GeneID:
123595979
NCBI-ProteinID:
XP_045329984
LinkDB
All DBs
Position
B1:complement(162103582..162157225)
Genome browser
AA seq
1089 aa
AA seq
DB search
MGTSHLALLVLVCLLTGPSLISCQLSLPSILPNENEKVVQLNSSFSLRCFGESEVSWQYP
MSEEENPNVEVRNEENNSGLFVTVLEVVNASAAHTGLYTCYYNHTQTDENEIEGRRIYIY
VPDPDVAFVPLGMTDYLVIVEDDDSAIIPCRTTDPKTPVTLRSSDGVVHASYDSRQGFNG
TFSVGPYICEATVSGKKFQTIPFNVYALKATSELDLEMEALKTVYKSGETIVVTCAVFNN
EVVDLQWTYPGEVKGKGITMLEEIKVPSIKLVYTLTVPEATVKDSGDYECAARQATKEVK
EMKKVTISVHEKGFIEIKPNFSPLEAVDLHEVKHFVVDVQAYPPPRISWLKDNLTLIENL
TEITTDIEKIQEIRYRSKLKLIRAKEEDSGHYTIVVQNEDDVKSYTFELLTQVPSSILDL
VDDHHGSTGGQTVRCTAEGTPLPDIEWMICKDIKKCNNETSWTVLANNISNIITEVHRRD
RSTVEGRVTFTRVEETIAVRCLAKNLLGAENRELKLVAPTLRSELTVAAAVLVLLVIVII
SLIVLVVIWKQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRILG
SGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVNL
LGACTKSGPIYIITEYCFYGDLVNYLHKNRDSFLSRHPEKPKKELDIFGLNPADESTRSY
VILSFENNGDYMDMKQADTTQYVPMLERKEVSKYSDIQRSLYDRPASYKKKSTSDSEVKN
LLSDDNSEGLTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLA
RDIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMM
VDSTFYNKIKNGYRMAKPDHATSEVYEIMVKCWHSEPEKRPSFYHLSEIVENLLPGQYKK
SYEKIHLDFLKSDHPAVARMRVDSDNAYIGVTYKHEEDKLKDWEGSLDEQRLSADSGYII
PLPDIDPVPEEEDLGKRNRHSSQTSEESAIETGSSSSTFVKREDETIEDIDMMDDIGIDS
SDLVEDSFL
NT seq
3270 nt
NT seq
+upstream
nt +downstream
nt
atggggacttcccacctggcgctcctggtgttagtctgtctcctcacaggaccgagccta
atctcctgccagctttcattaccctctatccttccaaacgaaaatgaaaaggtcgtgcag
ctgaattcttccttttctctgcgatgctttggggagagtgaagtgagctggcagtacccc
atgtctgaagaagagaaccccaatgtggaagtcagaaatgaagaaaacaacagtggcctt
tttgtgacggtgctggaagtggtcaatgcgtcggcggcccacacgggactgtacacttgc
tattacaaccacactcagacggacgaaaacgagatcgaaggcaggcgcatttacatctat
gtcccagacccagacgtagccttcgtacctctaggaatgacagattatttagttatcgtg
gaggacgatgactctgccatcataccttgtcgcacaactgatcccaagactccggttacc
ttacgcagcagtgacggggtggtacacgcctcctatgacagcagacagggctttaatggg
accttcagcgtcgggccctatatctgcgaagccacagtcagcgggaagaagttccagacc
atcccatttaatgtttatgctttaaaagcaacatcagaacttgatctagaaatggaagct
ctcaaaactgtctataagtcaggggagacgattgtggtcacctgcgccgtctttaacaac
gaggtggttgaccttcagtggacttaccctggagaagtgaaaggcaaaggcatcacgatg
ctggaggagatcaaggtcccgtccatcaaactggtttacactctgacggtccccgaggcc
acggtgaaggatagtggagattatgaatgtgctgcccgccaggccaccaaggaggtcaaa
gagatgaagaaagtcaccatttccgtccatgagaaagggttcattgaaatcaaacccaac
ttcagcccgttggaggctgtcgacctgcatgaagtcaaacatttcgtggtggacgtgcag
gcctacccccctcccaggatatcctggctgaaggacaacctgactctgattgaaaatctc
acggagatcaccaccgacatagaaaagattcaggaaataaggtatcgaagcaaattaaag
ctgatccgtgcgaaggaagaagacagtggccattacactattgtcgtccaaaatgaagac
gacgtgaagagctatactttcgaactcctaacgcaagttccctcgtctattctggacttg
gtcgacgaccaccatggctccaccgggggacagactgtgagatgcacagcagaagggaca
cctcttcccgatatcgagtggatgatttgcaaggatattaagaaatgtaataacgaaact
tcatggacggttttggcgaacaacatctcgaacatcatcacggaggtccaccgccgggac
aggagtactgtggagggccgagtgacgttcaccagagtggaggagaccatcgccgttcga
tgcctggccaagaatcttcttggagccgagaaccgagagctgaagctggtggctcccacg
ctgcgttctgaactcacagtggcggctgcagtcctggtcctgctggtgattgtgatcatc
tccctcattgtcctggttgtcatttggaaacagaaaccgaggtatgaaattcgttggagg
gtcattgaatcgatcagccccgatggacatgaatatatttacgtggacccgatgcagctg
ccttatgactctagatgggagtttccaagagatggactagtgcttggtcgtatcctggga
tctggtgcgttcgggaaagtggtcgaaggaactgcctatggattgagccggtcccagcct
gtcatgaaagtagcagtaaagatgctaaaacccacagccagatccagtgaaaaacaagct
ctcatgtcggaactgaagataatgactcacctggggccccatttaaacattgtgaacttg
ctgggggcctgcaccaagtcgggccctatttacatcatcacggagtactgcttctatggg
gatttggtcaactatttgcataagaatagggacagcttcctgagccgacacccagagaag
ccaaagaaagagttggacatttttgggctgaaccctgctgatgaaagcacacggagttac
gttattttatcttttgaaaacaatggtgactacatggacatgaagcaagctgataccaca
cagtacgtccccatgctggaaaggaaagaggtttctaaatactcggacatccagagatcg
ctgtatgatcgcccggcctcgtataagaagaaatctacgtcagactcggaagtcaaaaac
ctcctttcggacgataactcagaaggcctgactctgctggatttgttgagctttacctat
caagtggcgcgagggatggaatttttggcttccaaaaattgtgtccaccgggacctggct
gctcgcaacgtcctcctggcgcaagggaaaatcgtgaagatctgtgacttcggcctggcc
agggacatcatgcacgattcaaactacgtgtccaaaggcagcacctttctccccgtgaag
tggatggctcctgagagcatcttcgacaacctctacaccacgctgagtgacgtctggtct
tacggcattctgctctgggagatcttttcccttgggggcaccccgtaccctggcatgatg
gtggattccactttctacaacaagatcaagaacgggtaccggatggccaagcctgaccac
gccaccagcgaagtctatgaaatcatggtcaagtgctggcacagtgagccggagaagaga
ccctccttttaccacctgagtgagattgtggagaatctgttgccgggacaatataagaag
agctacgaaaagattcacctggacttcttgaagagcgaccaccctgccgtggcgcgcatg
cgcgtggactcggacaacgcctacatcggcgtcacctacaaacacgaggaagacaagctg
aaggactgggaaggcagcctggacgagcagaggctgagtgcagacagcggctacatcatc
cctctgcccgacatcgaccctgttcctgaggaggaggacctgggcaagaggaacagacac
agctcgcagacctcagaagagagcgccattgagacaggttccagcagctctactttcgtc
aagagagaggatgaaaccatcgaggacatcgacatgatggatgacattggcatagactcc
tcagacctggtagaggacagcttcctgtga
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