Leopardus geoffroyi (Geoffroy's cat): 123598014
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Entry
123598014 CDS
T10761
Symbol
JAK1
Name
(RefSeq) tyrosine-protein kinase JAK1 isoform X1
KO
K11217
Janus kinase 1 [EC:
2.7.10.2
]
Organism
lgf Leopardus geoffroyi (Geoffroy's cat)
Pathway
lgf01521
EGFR tyrosine kinase inhibitor resistance
lgf04151
PI3K-Akt signaling pathway
lgf04217
Necroptosis
lgf04380
Osteoclast differentiation
lgf04550
Signaling pathways regulating pluripotency of stem cells
lgf04620
Toll-like receptor signaling pathway
lgf04621
NOD-like receptor signaling pathway
lgf04630
JAK-STAT signaling pathway
lgf04658
Th1 and Th2 cell differentiation
lgf04659
Th17 cell differentiation
lgf05140
Leishmaniasis
lgf05145
Toxoplasmosis
lgf05152
Tuberculosis
lgf05160
Hepatitis C
lgf05161
Hepatitis B
lgf05162
Measles
lgf05163
Human cytomegalovirus infection
lgf05164
Influenza A
lgf05165
Human papillomavirus infection
lgf05166
Human T-cell leukemia virus 1 infection
lgf05167
Kaposi sarcoma-associated herpesvirus infection
lgf05168
Herpes simplex virus 1 infection
lgf05169
Epstein-Barr virus infection
lgf05171
Coronavirus disease - COVID-19
lgf05200
Pathways in cancer
lgf05203
Viral carcinogenesis
lgf05212
Pancreatic cancer
lgf05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
lgf00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
123598014 (JAK1)
04151 PI3K-Akt signaling pathway
123598014 (JAK1)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
123598014 (JAK1)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
123598014 (JAK1)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
123598014 (JAK1)
04621 NOD-like receptor signaling pathway
123598014 (JAK1)
04658 Th1 and Th2 cell differentiation
123598014 (JAK1)
04659 Th17 cell differentiation
123598014 (JAK1)
09158 Development and regeneration
04380 Osteoclast differentiation
123598014 (JAK1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
123598014 (JAK1)
05203 Viral carcinogenesis
123598014 (JAK1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
123598014 (JAK1)
09162 Cancer: specific types
05212 Pancreatic cancer
123598014 (JAK1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
123598014 (JAK1)
05161 Hepatitis B
123598014 (JAK1)
05160 Hepatitis C
123598014 (JAK1)
05171 Coronavirus disease - COVID-19
123598014 (JAK1)
05164 Influenza A
123598014 (JAK1)
05162 Measles
123598014 (JAK1)
05168 Herpes simplex virus 1 infection
123598014 (JAK1)
05163 Human cytomegalovirus infection
123598014 (JAK1)
05167 Kaposi sarcoma-associated herpesvirus infection
123598014 (JAK1)
05169 Epstein-Barr virus infection
123598014 (JAK1)
05165 Human papillomavirus infection
123598014 (JAK1)
09171 Infectious disease: bacterial
05152 Tuberculosis
123598014 (JAK1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
123598014 (JAK1)
05140 Leishmaniasis
123598014 (JAK1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
123598014 (JAK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
lgf01001
]
123598014 (JAK1)
Enzymes [BR:
lgf01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
123598014 (JAK1)
Protein kinases [BR:
lgf01001
]
Non-receptor tyrosine kinases
JAK family [OT]
123598014 (JAK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
SH2_1
FERM_F1
ABC1
SH2
RIO1
FERM_C_FAK1
Endonuclea_NS_2
Motif
Other DBs
NCBI-GeneID:
123598014
NCBI-ProteinID:
XP_045333641
LinkDB
All DBs
Position
C1:complement(53497322..53744224)
Genome browser
AA seq
1156 aa
AA seq
DB search
MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVLFYLSDREPLRLGSGEYTAEEL
CIRAAQECCISPLCHNLFALYDENTKLWYAPNRTITVDDKTSLRLHYRMRFYFTNWHGTN
DNEQSVWRHSPKKQKNGYEKKKVPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
WFHPDDSGNILYEVMVTGNLGIQWRQKPNVVPVEKEKNKLKWKKLENKHKKDEEKNKIRE
EWNNFSYFPEITHIVIKECVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAHH
YLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVTC
FEKSEVVGSQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMNHLKKQILRTDNISFVLKR
CCQPKPREISNLLVATKKAQEWQPVYSMSQLSFDRILKKDIVQGEHLGRGTRTHIYSGTL
LDYKDDEGTSEEKRIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDVE
NIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLLL
AREGIDSEFGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFGTT
LWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAIM
RDINKLEEQNPDIVSERKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNTG
EQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPSG
SLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGDF
GLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDSDS
SPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPTNRTTF
QNLIKGFEALLEALLK
NT seq
3471 nt
NT seq
+upstream
nt +downstream
nt
atgcagtatctaaatataaaagaggactgcaatgccatggctttctgtgctaaaatgagg
agctccaagaagacggaggtgaatctggaggcccccgaaccaggggtggaagtgctcttc
tatctgtccgatagggagccgctccggctgggcagcggggagtacacggcagaggagctg
tgcatcagggcggcgcaggaatgctgtatctctcctctgtgtcacaacctttttgccctg
tatgatgagaacaccaagctttggtacgctccgaatcgcacgatcacagttgacgacaag
acatcactccggctccactaccggatgaggttctatttcaccaactggcatgggaccaat
gataatgagcagtctgtatggcgacattctccgaagaagcagaaaaatggctatgagaaa
aaaaaagttccagatgcaacccctctccttgacgccagctccctggaatatctgtttgct
cagggacaatacgatttggtcaaatgcctggctcccattcgagaccccaagaccgagcag
gatggacacgatattgagaacgagtgtctgggaatggctgtcctggccatctcccactac
gccatgatgaagaagatgcaattgccagaactgcccaaggacatcagctacaagcgatat
atcccagaaacattgaataagtccatcaggcagaggaatcttctcaccaggatgcggata
aataacgttttcaaggatttcctaaaggaatttaacaacaagaccatctgtgacagcagt
gtatctactcatgacctgaaggtgaaatacctggcgaccttggagactttgacaaaacat
tatggtgctgaaatatttgagacttccatgttactgatttcgtcagaaaatgagatgaat
tggtttcatccagatgacagtggaaacattctctatgaagtgatggtaactggaaatctt
ggaatccagtggagacagaaaccaaatgttgttcctgttgaaaaggaaaaaaacaaactg
aaatggaaaaagctggaaaataaacacaagaaggatgaggagaaaaacaaaatccgggaa
gagtggaacaatttttcttacttccctgaaatcactcacattgtaataaaggagtgtgtg
gtcagcatcaataagcaggacaataaaaaaatggaactgaagctttcgtcccacgaggag
gccttgtcctttgtgtccctggtagacggctacttccggctcacagcagatgcccatcat
tacctctgcactgatgtggctcccccactgattgtccacaacatacagaatggttgtcac
ggtcccatctgcacagaatatgccatcaataagttgcggcaagaaggaagcgaggaggga
atgtatgtgctgaggtggagctgtaccgactttgacaatatcctcatgactgtcacctgc
tttgaaaaatctgaggtggtgggtagccagaaacagttcaagaactttcagatcgaggtg
cagaagggccgttacagcctgcatggctcggaccgcagcttccccagcctgggggacctc
atgaaccacctcaagaaacagatcctgcggacggacaacatcagcttcgtgctgaaacgc
tgctgccagcccaagccccgagagatctccaatttgctggtggctactaagaaagcccag
gagtggcagcccgtctactctatgagccagctgagttttgaccggatcctcaagaaagat
atcgtgcaaggcgagcaccttgggagaggcacgcggacgcacatctactctggaaccctt
ctggattacaaagatgacgaaggaacttccgaagaaaagagaataaaagtgatcctcaaa
gtcttagaccccagccacagggacatttctctggccttctttgaggcagccagcatgatg
aggcaggtctcccacaaacacattgtgtacctctatggtgtctgtgtccgagacgtggaa
aatatcatggtggaagagtttgtggagggggggcccctggatctcttcatgcaccggaaa
agcgatgtcctcaccacaccgtggaagtttaaagttgccaaacaactggccagtgccttg
agttacttggaggataaagacctggtccacggaaatgtgtgcaccaaaaacctcctcttg
gcccgtgagggcatcgacagcgagttcggcccgttcatcaagctcagtgaccccggcatc
cccatcaccgtgctgtccaggcaagagtgcatagagcgaatcccgtggattgctcccgag
tgtgttgaagactccaagaacctgagtgtggccgctgacaaatggagctttggaaccaca
ctctgggaaatctgctacaatggcgagattcctctgaaagacaagacactgattgagaaa
gagcgattctatgaaagccggtgccggccagtgacaccatcttgtaaggagctggctgac
ctcatgacccgctgcatgaactatgaccccaaccagagacccttcttccgagccatcatg
agagacatcaataaactggaggagcagaatccagacattgtttcagaacgaaagccggca
accgaagtggatcccacacattttgaaaagcggttcttgaagagaatccgtgacttggga
gagggccactttgggaaggttgagctctgcagatacgaccctgagggtgacaataccggg
gagcaggtggctgtcaaatccctgaagcctgagagtggaggtaaccacatagctgatctg
aagaaggaaattgaaatcttaaggaacctctatcatgagaacattgtgaagtacaaaggc
atctgtacagaagacggaggaaatggtattaagctcatcatggagtttctaccttcagga
agccttaaggaatatcttccaaagaataagaacaaaattaacctcaaacaacagttaaaa
tatgctgttcagatttgtaaggggatggactacttggggtctcggcagtacgttcaccgg
gacttagcagcaagaaatgtcctcgttgagagtgagcaccaagtgaaaattggagacttc
ggtttaaccaaagccattgaaaccgacaaagagtactacacagtcaaggatgatcgggac
agccctgtgttttggtatgctccagaatgtttaattcagtgtaaattttatatcgcctct
gatgtctggtcgtttggagtgactctgcatgagctgctcacttactgtgattccgattcc
agccccatggcattgttcctgaaaatgataggcccaacgcatggccagatgacagtcaca
agacttgtgaacacgttaaaagaaggaaaacgtttgccctgtccacctaactgcccagat
gaggtttatcaactcatgagaaagtgctgggaattccaaccaactaataggacaactttt
cagaacctaattaaaggatttgaagcacttttagaagcacttttaaaataa
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