Leopardus geoffroyi (Geoffroy's cat): 123603625
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Entry
123603625 CDS
T10761
Symbol
TOP2A
Name
(RefSeq) DNA topoisomerase 2-alpha
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
lgf Leopardus geoffroyi (Geoffroy's cat)
Pathway
lgf01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
lgf00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
123603625 (TOP2A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
lgf03032
]
123603625 (TOP2A)
03036 Chromosome and associated proteins [BR:
lgf03036
]
123603625 (TOP2A)
Enzymes [BR:
lgf01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
123603625 (TOP2A)
DNA replication proteins [BR:
lgf03032
]
Eukaryotic type
DNA Topoisomerases
123603625 (TOP2A)
Chromosome and associated proteins [BR:
lgf03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
123603625 (TOP2A)
Centrosome formation proteins
Centriole proteins
123603625 (TOP2A)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
HATPase_c
Toprim
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
123603625
NCBI-ProteinID:
XP_045344711
LinkDB
All DBs
Position
E1:complement(39179045..39208157)
Genome browser
AA seq
1534 aa
AA seq
DB search
MEVSPLQPVNENMLINKTKKNEDAKKRLSIERIYQKKTQLEHILLRPDTYIGSVELVTQQ
MWVYDEDIGINYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWN
NGKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVE
TASREYKKMFKQTWMDNMGRAGEMELKPFNGEDYTCITFQPDLSKFKMQSLDKDIVALMV
RRAYDIAGSTKDVKVFLNGNKLPVKGFRSYVDMYLKDKVDETGNPLKIIHEQVNPRWEVC
LTMSEKGFQQISFVNSIATSKGGRHVDYIADQIVTKLVEVVKKKNKGGVAVKAHQVKNHM
WIFVNALIENPTFDSQTKENMTLQVKSFGSTCHLSEKFIKAAIGCGIVESILNWVKFKAQ
VQLNKKCSAVKHNRIKGIPKLDDANDAGGRNSNECTLILTEGDSAKTLAVSGLGVVGRDK
YGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMT
DQDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEMAFYSLPEFEEWKS
STPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQIDD
RKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVD
GLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNN
LNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLKFLYDDNQRVEPEW
YIPIIPMVLINGAEGIGTGWSCKIPNFDIREVVNNIRRLMDGEEPLPMLPSYKNFRGTIE
ELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYREY
HTDTTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILR
DFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQR
GYDSDPVKAWKEAQQKVPDEEENEESDNENEAEKGDSVKDSGPTFNYLLDMPLWYLTKEK
KDELCKLRNEKEQELETLKRKSPSDLWKEDLAAFIEELEAVETKEKQEEQIGLPGKGGKA
KGKKIQMAEVLPSPCGKRVIPRVTIEMKAEAEKKIKKKIKSENTEGSPQEDGMELEGLKQ
RLEKKQKREPGTKTKKQTTLPFKPVKKGKKRNPWSDSESDMSSNESDFDVPPREIEPRRA
ATKTKFTVDLDSDDDFSDFDEKTQDEDFVPSDVSPVKTKTSPPVPTNKELKPQKSATSVM
DLDAGGAKDSVPPSLDSPAADFSAETEIINPVSKKKVAVKKTAAKSQSSTSTTGAKKRAA
PKGTKKEPGLNSDVSQKPDPPKTKNRRKRKPSTSDDSDSNFEKMISKTVTSKKSKGESED
FHLDLDSAVAPRAKSGRAKKPIKYLEESDEDDLF
NT seq
4605 nt
NT seq
+upstream
nt +downstream
nt
atggaggtgtcaccactgcagcctgtaaatgaaaatatgctaatcaacaaaacaaagaaa
aatgaagatgccaagaaaagactgtctattgaaaggatctatcaaaagaaaacccaactg
gaacatattttgctccgcccagacacctatattggctccgtggaattagtgacccagcaa
atgtgggtttacgatgaagatattggcattaactatagggaagtcacctttgtccctggg
ttgtacaaaatctttgatgagattctagtcaatgctgcagacaacaaacaaagggaccca
aaaatgtcttgtattagagtcacaattgacccggaaaacaatttaattagtatatggaat
aatgggaaaggtattcctgttgttgaacacaaagttgagaagatgtatgtcccagctctc
atctttggacagctcctaacttctagtaactatgatgatgatgaaaagaaagtaacaggc
ggtcgaaatggctatggggccaaattgtgtaacatattcagtaccaagtttactgtggaa
acagccagtagagaatacaagaaaatgttcaaacagacgtggatggataacatgggaagg
gctggtgagatggaactcaagcccttcaatggggaagattatacatgtattaccttccaa
cctgatttgtccaagtttaaaatgcaaagcctagacaaagatatcgttgcactaatggtc
agaagagcgtatgatattgctggatccactaaagatgtcaaagtgtttctcaatggaaat
aagctgccagtaaaaggattccgtagctatgtagatatgtatttgaaggataaggtagat
gaaactggcaatccgttgaaaattatccatgaacaagtaaaccccaggtgggaagtatgc
ttaacaatgagtgaaaaaggctttcagcaaattagctttgtcaacagcattgctacttcc
aagggtggcagacatgttgattatatagctgatcagattgtgactaaacttgttgaggtt
gttaaaaagaagaacaagggtggtgttgcagtaaaagcacatcaggtgaaaaatcacatg
tggatttttgtgaatgccttaattgaaaacccaacctttgattctcagacaaaagagaac
atgactttacaagtcaagagctttggatcaacctgccatttaagtgaaaaattcatcaaa
gctgcaattggttgtggtattgtagaaagcatactaaactgggtgaagtttaaggcccaa
gtccagttaaacaagaagtgttcagctgtaaaacataacaggatcaagggaattcccaaa
ctcgatgatgccaatgatgcagggggtcgaaactccaatgagtgtacacttatcctgact
gagggagactcagctaaaactttggctgtttcaggccttggtgtggttgggagagacaaa
tatggggttttcccgcttagaggaaaaatactcaatgttcgagaagcttctcataaacag
atcatggaaaatgctgaaattaacaatatcatcaagattgtgggtcttcagtacaagaaa
aactatgaagatgaagattcattgaagactcttcgttatgggaagataatgattatgaca
gatcaggaccaagatggttcccatatcaaaggcttgctgattaattttatccatcacaac
tggccctctcttctgcgacaccgctttctggaagaatttatcactcctattgtaaaggtg
tctaaaaacaagcaagaaatggcattctatagccttcctgaatttgaagaatggaagagt
tctacaccaaatcataaaaaatggaaagtcaagtactacaaaggtttgggcacgagcaca
tcaaaagaggctaaggaatactttgcagatatgaaaagacatcgtattcaattcaaatat
tccggtcctgaagatgatgccgccatcagcctggcctttagcaagaaacagatagatgat
cgaaaggaatggttaactcatttcatggaggacagaaggcaacggaagttacttggcctt
cctgaggattacttgtatgggcaaactaccacatatctgacatacaatgacttcataaac
aaggaacttatcctgttctcaaattctgataacgagagatctattccatctatggtagat
ggtttgaaaccaggtcaaagaaaggttttgtttacctgtttcaaacggaatgacaagcga
gaggtgaaggttgctcagttagctgggtcagtggctgagatgtcctcttatcatcatggt
gagatgtcactaatgatgaccattatcaatttggctcagaattttgtgggtagcaataat
ctgaatctcttgcaacccattggtcagtttggtaccaggctgcatggtggtaaggattct
gctagtcctcgatacatcttcacaatgctcagccctttggctcggttgttatttccacca
aaagatgatcatacattaaagtttttatatgatgacaatcaacgtgttgaacctgaatgg
tacattcctattatacccatggtgctgataaatggtgctgaaggaatcggtactgggtgg
tcctgcaaaatcccgaactttgatattcgtgaagttgtaaataatatcaggcgtctgatg
gatggagaagaacctttgccaatgcttccgagttacaagaacttcaggggtacgattgaa
gagctggctccaaatcaatatgtgattagtggtgaagtggctattcttaattccacaacc
attgaaatctcagaacttcccatcagaacatggacccagacatataaagaacaggttcta
gaacccatgttgaatggcactgagaagacaccacctctcataaccgattatagggaatac
catacagacaccactgtgaagtttgttgtgaagatgactgaagagaaattggcagaggca
gagagagtgggactacacaaagtcttcaaactccaaactagtctcacatgcaactctatg
gtgctttttgaccatgtaggatgtttaaagaaatatgacacagtgttggatattctaaga
gacttctttgaactcaggcttaaatattatggattaagaaaagaatggctactaggaatg
cttggtgctgaatctgctaaactgaacaatcaggctcgctttatcttagagaaaatagat
ggcaaaataatcattgaaaataagccaaagaaggaattaattaaagttctgattcagagg
ggttatgattctgatcctgtgaaggcttggaaagaagcccagcaaaaggtaccagatgaa
gaagaaaatgaagagagtgacaatgaaaatgaagctgaaaagggtgactctgtaaaagat
tctggaccaaccttcaactaccttcttgatatgcctctttggtatctcaccaaggaaaag
aaggatgaactgtgcaagctgagaaatgaaaaagaacaagagctagaaacattaaagaga
aagagtccatcagatttgtggaaagaagacctagctgcttttattgaagagctggaggct
gttgaaacaaaggaaaaacaagaagaacaaataggtctccctgggaaaggggggaaagca
aaggggaaaaaaatacagatggctgaagttttgccttctccatgtgggaaaagagtcatc
ccccgagtgaccatagagatgaaagcagaggcagaaaagaaaattaaaaagaaaattaag
agtgaaaacactgaagggagccctcaagaggatggtatggaactagaaggtctgaaacaa
aggttggagaagaaacagaaaagagaaccaggtaccaagacaaagaagcaaactacgttg
ccatttaaaccagtcaaaaaaggaaagaagagaaacccctggtctgattcagaatcagat
atgagcagtaatgaaagtgactttgatgttcccccacgagagatagagccacggagagca
gcaacaaaaaccaaatttacagtggatttggattcagatgatgatttctcagattttgat
gaaaaaactcaagatgaggattttgtcccatcagatgttagcccagttaagaccaaaact
tccccaccagtacctactaacaaagaactgaagccacagaagagtgccacatcagtaatg
gaccttgatgctggtggtgccaaggacagtgtaccaccttctctagattctccggccgct
gatttctcagctgaaactgaaatcataaaccctgtttctaaaaagaaggtagcggtgaag
aagacagcagcaaaaagtcagtcttccacctccactacaggtgccaaaaaaagggctgca
ccaaaaggaaccaaaaaggagccaggcttgaattctgatgtctctcaaaagcctgatcct
cccaaaaccaaaaatcgccgcaaaaggaagccatccacttctgatgattctgactctaat
tttgagaaaatgatttctaagacagtcacaagcaagaaatccaagggggagagtgaggat
ttccatctggacttagactcagctgtggctcctcgggccaaatctggacgggcaaagaaa
cctataaagtacctcgaagaatcagatgaagatgatctgttctaa
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integrated database retrieval system
