KEGG   Leopardus geoffroyi (Geoffroy's cat): 123603984
Entry
123603984         CDS       T10761                                 
Symbol
MAP2K6
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6 isoform X1
  KO
K04433  mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
lgf  Leopardus geoffroyi (Geoffroy's cat)
Pathway
lgf04010  MAPK signaling pathway
lgf04015  Rap1 signaling pathway
lgf04218  Cellular senescence
lgf04380  Osteoclast differentiation
lgf04620  Toll-like receptor signaling pathway
lgf04664  Fc epsilon RI signaling pathway
lgf04668  TNF signaling pathway
lgf04750  Inflammatory mediator regulation of TRP channels
lgf04912  GnRH signaling pathway
lgf04935  Growth hormone synthesis, secretion and action
lgf04936  Alcoholic liver disease
lgf05014  Amyotrophic lateral sclerosis
lgf05022  Pathways of neurodegeneration - multiple diseases
lgf05132  Salmonella infection
lgf05135  Yersinia infection
lgf05145  Toxoplasmosis
lgf05161  Hepatitis B
lgf05163  Human cytomegalovirus infection
lgf05167  Kaposi sarcoma-associated herpesvirus infection
lgf05169  Epstein-Barr virus infection
lgf05170  Human immunodeficiency virus 1 infection
lgf05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
lgf05417  Lipid and atherosclerosis
lgf05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:lgf00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    123603984 (MAP2K6)
   04015 Rap1 signaling pathway
    123603984 (MAP2K6)
   04668 TNF signaling pathway
    123603984 (MAP2K6)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    123603984 (MAP2K6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    123603984 (MAP2K6)
   04664 Fc epsilon RI signaling pathway
    123603984 (MAP2K6)
  09152 Endocrine system
   04912 GnRH signaling pathway
    123603984 (MAP2K6)
   04935 Growth hormone synthesis, secretion and action
    123603984 (MAP2K6)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    123603984 (MAP2K6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    123603984 (MAP2K6)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    123603984 (MAP2K6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    123603984 (MAP2K6)
   05161 Hepatitis B
    123603984 (MAP2K6)
   05163 Human cytomegalovirus infection
    123603984 (MAP2K6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    123603984 (MAP2K6)
   05169 Epstein-Barr virus infection
    123603984 (MAP2K6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    123603984 (MAP2K6)
   05135 Yersinia infection
    123603984 (MAP2K6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    123603984 (MAP2K6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    123603984 (MAP2K6)
   05022 Pathways of neurodegeneration - multiple diseases
    123603984 (MAP2K6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    123603984 (MAP2K6)
   05418 Fluid shear stress and atherosclerosis
    123603984 (MAP2K6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    123603984 (MAP2K6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:lgf01001]
    123603984 (MAP2K6)
Enzymes [BR:lgf01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     123603984 (MAP2K6)
Protein kinases [BR:lgf01001]
 Serine/threonine kinases: STE group
  STE7 family
   123603984 (MAP2K6)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_fungal Seadorna_VP7 Choline_kinase Haspin_kinase CLP1_P DUF4344 APH
Other DBs
NCBI-GeneID: 123603984
NCBI-ProteinID: XP_045345515
LinkDB
Position
E1:50455656..50572149
AA seq 334 aa
MSQSKGRKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIMELG
RGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALF
REGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDV
KPSNVLINTLGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDI
WSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPGDKFTEEFVDFTSQCLKKNSK
ERPTYPELMQHPFFTLHESKATDVASFVKLILGD
NT seq 1005 nt   +upstreamnt  +downstreamnt
atgtctcagtcgaaaggcaggaagcgaaaccctggccttaaaattccaaaagaagcattt
gaacaacctcagaccagttccacgccacctcgagacttagactccaaagcttgcatttct
attggaaatcagaactttgaggtgaaggcagatgatctggaaccaataatggaactgggg
cgaggtgcgtacggggtcgtggagaagatgcgacacgtgcccagcgggcagatcatggcg
gtgaagcggatccgggccacagtaaatagccaggagcagaaaaggctactgatggatttg
gatatttccatgaggacagtggactgtcctttcacagtcaccttttatggtgcactcttc
cgggagggtgatgtttggatttgcatggaactcatggatacgtcgctagataaattctac
aaacaagtgattgacaaaggccaaacaattccagaggacatcttagggaaaatagcagtt
tctattgtaaaggcgttagaacatttacacagtaagctctctgtcattcatcgagacgtc
aagccttccaacgtgctgatcaacactctgggccaagtaaagatgtgcgattttggaatc
agtggctaccttgtagactcagtcgctaaaaccattgatgcaggatgcaaaccgtacatg
gcccccgaaagaataaacccagagctcaatcagaagggatatagtgtgaagtctgacatt
tggagtctgggcatcacaatgattgagttggcgatccttcggtttccctatgactcttgg
ggaactcccttccaacagctcaaacaggtggtagaggagccctcaccacagctcccggga
gacaagttcaccgaagagtttgttgactttacctcacagtgcttgaagaagaattccaaa
gaacggccaacatatccagaacttatgcaacatccatttttcaccctacacgaatccaaa
gcaacagacgtggcatcttttgtaaaattgattcttggagactaa

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